Macrophage deficiency of p38α MAPK promotes apoptosis and plaque necrosis in advanced atherosclerotic lesions in mice

Journal of Clinical Investigation

Volumn 119, Issue 4, 2009, Pages 886-898

  Seimon, Tracie A ^a   Wang, Yibin ^b   Han, Seongah ^a   Senokuchi, Takafumi ^a   Schrijvers, Dorien M ^a   Kuriakose, George ^a   Tall, Alan R ^a   Tabas, Ira A ^a,c  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c NewYork Presbyterian Hospital   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E; COLLAGEN; MITOGEN ACTIVATED PROTEIN KINASE 14; PROTEIN KINASE B; SYNAPTOPHYSIN;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ATHEROSCLEROTIC PLAQUE; CELL CULTURE; CELL DEATH; CELL SURVIVAL; CONTROLLED STUDY; DISEASE COURSE; ENDOPLASMIC RETICULUM STRESS; ENZYME INHIBITION; FEMALE; GENE REPRESSION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IN VITRO STUDY; IN VIVO STUDY; MACROPHAGE; MOUSE; MYRISTYLATION; NECROSIS; NONHUMAN; PLAQUE NECROSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; ATHEROSCLEROSIS; BIOLOGICAL MODEL; C57BL MOUSE; DRUG ANTAGONISM; ENDOPLASMIC RETICULUM; ENZYMOLOGY; GENETICS; METABOLISM; MOUSE MUTANT; PATHOLOGY; PERITONEUM MACROPHAGE; PHYSIOLOGICAL STRESS;

ANIMALS; APOLIPOPROTEINS E; APOPTOSIS; ATHEROSCLEROSIS; ENDOPLASMIC RETICULUM; FEMALE; HUMANS; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASE 14; MODELS, BIOLOGICAL; NECROSIS; PROTO-ONCOGENE PROTEINS C-AKT; STRESS, PHYSIOLOGICAL;

EID: 65249123061     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI37262     Document Type: Article

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