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Volumn 163, Issue 7, 2011, Pages 1402-1410

Endocannabinoids and traumatic brain injury

Author keywords

2 arachidonoyl glycerol; brain injury; N arachidonoyl L serine; neuroprotection

Indexed keywords

1 (2,4 DICHLOROPHENYL) 5 (4 IODOPHENYL) 4 METHYL N (1 PIPERIDYL) 1H PYRAZOLE 3 CARBOXAMIDE; 2 ARACHIDONOYLGLYCEROL; 2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; ALPHA DIACYLGLYCEROL LIPASE; BETA DIACYLGLYCEROL LIPASE; CANNABINOID 1 RECEPTOR; CANNABINOID 1 RECEPTOR AGONIST; CANNABINOID 2 RECEPTOR; ENDOCANNABINOID; HU 910; LIPOPROTEIN LIPASE; N ARACHIDONOYL L SERINE; SERINE; UNCLASSIFIED DRUG; ANANDAMIDE; CANNABINOID RECEPTOR; CENTRAL NERVOUS SYSTEM AGENTS; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPROTEIN LIPASE ALPHA; LIPOPROTEIN LIPASE BETA; N ARACHIDONOYL LEVO SERINE; NEUROPROTECTIVE AGENT; TUMOR NECROSIS FACTOR ALPHA; VANILLOID RECEPTOR 1;

EID: 79960333360     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2011.01343.x     Document Type: Review
Times cited : (136)

References (93)
  • 3
    • 0034638450 scopus 로고    scopus 로고
    • Cannabinoid 1 receptors are expressed in nociceptive primary sensory neurons
    • Ahluwalia J, Urban L, Capogna M, Bevan S, Nagy I, (2000). Cannabinoid 1 receptors are expressed in nociceptive primary sensory neurons. Neurosci 100: 685-688.
    • (2000) Neurosci , vol.100 , pp. 685-688
    • Ahluwalia, J.1    Urban, L.2    Capogna, M.3    Bevan, S.4    Nagy, I.5
  • 5
    • 72149097863 scopus 로고    scopus 로고
    • Guide to Receptors and Channels (GRAC), 4th edition
    • Alexander SPH, Mathie A, Peters JA, (2009). Guide to Receptors and Channels (GRAC), 4th edition. Br J Pharmacol 158 (Suppl. 1): S1-S254.
    • (2009) Br J Pharmacol , vol.158 , Issue.SUPPL. 1
    • Alexander, S.P.H.1    Mathie, A.2    Peters, J.A.3
  • 6
    • 34347397535 scopus 로고    scopus 로고
    • The cannabinoid CB2 receptor as a target for inflammation-dependent neurodegeneration
    • DOI 10.2174/157015907780866884
    • Ashton JC, Glass M, (2007). The cannabinoid CB2 receptor as a target for inflammation-dependent neurodegeneration. Curr Neuropharmacol 5: 73-80. (Pubitemid 47019422)
    • (2007) Current Neuropharmacology , vol.5 , Issue.2 , pp. 73-80
    • Ashton, J.C.1    Glass, M.2
  • 10
    • 34347375273 scopus 로고    scopus 로고
    • Neuropharmacology of the endocannabinoid signaling system-molecular mechanisms, biological actions and synaptic plasticity
    • DOI 10.2174/157015907780866910
    • Basavarajappa BS, (2007). Neuropharmacology of the endocannabinoid signaling system-molecular mechanisms, biological actions and synaptic plasticity. Curr Neuropharmacol 5: 81-97. (Pubitemid 47019423)
    • (2007) Current Neuropharmacology , vol.5 , Issue.2 , pp. 81-97
    • Basavarajappa, B.S.1
  • 11
    • 55749111251 scopus 로고    scopus 로고
    • Pharmacology of traumatic brain injury - Where is the 'golden bullet'?
    • Beauchamp K, Mutlak H, Smith WR, Shohami E, Stahel PF, (2008). Pharmacology of traumatic brain injury-where is the 'golden bullet'? Mol Med 14: 731-740.
    • (2008) Mol Med , vol.14 , pp. 731-740
    • Beauchamp, K.1    Mutlak, H.2    Smith, W.R.3    Shohami, E.4    Stahel, P.F.5
  • 12
    • 0030934088 scopus 로고    scopus 로고
    • Changes of biological reducing activity in rat brain following closed head injury: A cyclic voltammetry study in normal and heat-acclimated rats
    • Beit-Yannai E, Kohen R, Horowitz M, Trembovler V, Shohami E, (1997). Changes in biological reducing activity in rat brain following closed head injury: a cyclic voltammetry study in normal and acclimated rats. J Cereb Blood Flow & Metabol 17: 273-279. (Pubitemid 27161370)
    • (1997) Journal of Cerebral Blood Flow and Metabolism , vol.17 , Issue.3 , pp. 273-279
    • Beit-Yannai, E.1    Kohen, R.2    Horowitz, M.3    Trembovler, V.4    Shohami, E.5
  • 13
    • 1342268351 scopus 로고    scopus 로고
    • Melatonin-induced neuroprotection after closed head injury is associated with increased brain antioxidants and attenuated late-phase activation of NF-κB and AP-1
    • Beni SM, Kohen R, Reiter RJ, Tan D-X, Shohami E, (2004). Melatonin-induced neuroprotection after closed head injury is associated with increased brain antioxidants and attenuated late-phase activation of NF-κB and AP-1. FASEB J 18: 149-151.
    • (2004) FASEB J , vol.18 , pp. 149-151
    • Beni, S.M.1    Kohen, R.2    Reiter, R.J.3    Tan, D.-X.4    Shohami, E.5
  • 14
    • 14944367009 scopus 로고    scopus 로고
    • A glial endogenous cannabinoid system is upregulated in the brains of macaques with simian immunodeficiency virus-induced encephalitis
    • DOI 10.1523/JNEUROSCI.3923-04.2005
    • Benito C, Kim WK, Chavarria I, Hillard CJ, Mackie K, Tolon RM, et al,. (2005). A glial endogenous cannabinoid system is upregulated in the brains of macaques with simian immunodeficiency virus-induced encephalitis. J Neurosci 25: 2530-2536. (Pubitemid 40365164)
    • (2005) Journal of Neuroscience , vol.25 , Issue.10 , pp. 2530-2536
    • Benito, C.1    Kim, W.-K.2    Chavarria, I.3    Hillard, C.J.4    Mackie, K.5    Tolon, R.M.6    Williams, K.7    Romero, J.8
  • 16
    • 0033198288 scopus 로고    scopus 로고
    • Analysis of cannabinoid receptor binding and mRNA expression and endogenous cannabinoid contents in the developing rat brain during late gestation and early postnatal period
    • DOI 10.1002/(SICI)1098-2396(19990901)33:3<181::AID-SYN3>3.0.CO;2-R
    • Berrendero F, Sepe N, Ramos JA, Di Marzo V, Fernández-Ruiz JJ, (1999). Analysis of cannabinoid receptor binding and mRNA expression and endogenous cannabinoid contents in the developing rat brain during late gestation and early postnatal period. Synapse 33: 181-191. (Pubitemid 29372845)
    • (1999) Synapse , vol.33 , Issue.3 , pp. 181-191
    • Berrendero, F.1    Sepe, N.2    Ramos, J.A.3    Di Marzo, V.4    Fernandez-Ruiz, J.J.5
  • 18
    • 85009295914 scopus 로고    scopus 로고
    • Clinical significance of CSF glutamate concentrations following severe traumatic brain injury in humans
    • Brown JI, Baker AJ, Konasiewicz SJ, Moulton RJ, (1998). Clinical significance of CSF glutamate concentrations following severe traumatic brain injury in humans. J Neurotrauma 15: 253-263. (Pubitemid 28166577)
    • (1998) Journal of Neurotrauma , vol.15 , Issue.4 , pp. 253-263
    • Brown, J.I.M.1    Baker, A.J.2    Konasiewicz, S.J.3    Moulton, R.J.4
  • 19
    • 28844487137 scopus 로고    scopus 로고
    • Cannabinoid receptors in microglia of the central nervous system: Immune functional relevance
    • DOI 10.1189/jlb.0405216
    • Cabral GA, Marciano-Cabral F, (2005). Cannabinoid receptors in microglia of the central nervous system: immune functional relevance. J Leukoc Biol 78: 1192-1197. (Pubitemid 41779223)
    • (2005) Journal of Leukocyte Biology , vol.78 , Issue.6 , pp. 1192-1197
    • Cabral, G.A.1    Marciano-Cabral, F.2
  • 21
    • 0030777012 scopus 로고    scopus 로고
    • The capsaicin receptor: A heat-activated ion channel in the pain pathway
    • DOI 10.1038/39807
    • Caterina MJ, Schumacher MA, Tominaga M, Rosen TA, Levine JD, Julius D, (1997). The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 389: 816-824. (Pubitemid 27462969)
    • (1997) Nature , vol.389 , Issue.6653 , pp. 816-824
    • Caterina, M.J.1    Schumacher, M.A.2    Tominaga, M.3    Rosen, T.A.4    Levine, J.D.5    Julius, D.6
  • 23
    • 0035149749 scopus 로고    scopus 로고
    • Reactive oxygen radicals in signaling and damage in the ischemic brain
    • Chan PH, (2001). Reactive oxygen radicals in signaling and damage in the ischemic brain. J Cereb Blood Flow Metab 21: 2-14. (Pubitemid 32036708)
    • (2001) Journal of Cerebral Blood Flow and Metabolism , vol.21 , Issue.1 , pp. 2-14
    • Chan, P.H.1
  • 26
    • 0028789274 scopus 로고
    • Endothelium-dependent hyperpolarization beyond nitric oxide and cyclic GMP
    • Cohen RA, Vanhoutte PM, (1995). Endothelium-dependent hyperpolarization beyond nitric oxide and cyclic GMP. Circulation 92: 3337-3349.
    • (1995) Circulation , vol.92 , pp. 3337-3349
    • Cohen, R.A.1    Vanhoutte, P.M.2
  • 29
    • 50249101147 scopus 로고    scopus 로고
    • Inhibition of endocannabinoid metabolism attenuates enhanced hippocampal neuronal activity induced by kainic acid
    • Coomber B, O'Donoghue MF, Mason R, (2008). Inhibition of endocannabinoid metabolism attenuates enhanced hippocampal neuronal activity induced by kainic acid. Synapse 62: 746-755.
    • (2008) Synapse , vol.62 , pp. 746-755
    • Coomber, B.1    O'Donoghue, M.F.2    Mason, R.3
  • 33
    • 29244478635 scopus 로고    scopus 로고
    • Stimulation of cannabinoid receptor 2 (CB2) suppresses microglial activation
    • Ehrhart J, Obregon D, Mori T, Hou H, Sun N, Bai Y, et al,. (2005). Stimulation of cannabinoid receptor 2 (CB2) suppresses microglial activation. J Neuroinflammation 12: 2-29.
    • (2005) J Neuroinflammation , vol.12 , pp. 2-29
    • Ehrhart, J.1    Obregon, D.2    Mori, T.3    Hou, H.4    Sun, N.5    Bai, Y.6
  • 35
    • 0024365739 scopus 로고
    • The role of excitatory amino acids and NMDA receptors in traumatic brain injury
    • Faden AI, Demediuk P, Panter SS, Vink R, (1989). The role of excitatory amino acids and NMDA receptors in traumatic brain injury. Science 244: 798-800. (Pubitemid 19163864)
    • (1989) Science , vol.244 , Issue.4906 , pp. 798-800
    • Faden, A.I.1    Demediuk, P.2    Panter, S.S.3    Vink, R.4
  • 36
    • 0035142863 scopus 로고    scopus 로고
    • Severe traumatic brain injury
    • DOI 10.1016/S0300-9572(00)00321-X, PII S030095720000321X
    • Finfer SR, Cohen J, (2001). Severe traumatic brain injury. Resuscitation 48: 77-90. (Pubitemid 32121667)
    • (2001) Resuscitation , vol.48 , Issue.1 , pp. 77-90
    • Finfer, S.R.1    Cohen, J.2
  • 37
    • 0142038864 scopus 로고    scopus 로고
    • 2 and abnormal-cannabidiol-sensitive receptors
    • DOI 10.1016/S0014-2999(03)02074-0
    • Franklin A, Stella N, (2003). Arachidonylcyclopropylamide increases microglial cell migration through cannabinoid CB2 and abnormal-cannabidiol- sensitive receptors. Eur J Pharmacol 474: 195-198. (Pubitemid 37281448)
    • (2003) European Journal of Pharmacology , vol.474 , Issue.2-3 , pp. 195-198
    • Franklin, A.1    Stella, N.2
  • 38
    • 0034613209 scopus 로고    scopus 로고
    • 2-Arachidonylglycerol, an endogenous cannabinoid, inhibits tumor necrosis factor-alpha production in murine macrophages, and in mice
    • Gallily R, Breuer A, Mechoulam R, (2000). 2-Arachidonylglycerol, an endogenous cannabinoid, inhibits tumor necrosis factor-alpha production in murine macrophages, and in mice. Eur J Pharmacol 406: R5-R7.
    • (2000) Eur J Pharmacol , vol.406
    • Gallily, R.1    Breuer, A.2    Mechoulam, R.3
  • 40
    • 34047156445 scopus 로고    scopus 로고
    • The endocannabinoid system and neurogenesis in health and disease
    • DOI 10.1177/1073858406296407
    • Galve-Roperh I, Aguado T, Palazuelos J, Guzmán M, (2007). The endocannabinoid system and neurogenesis in health and disease. Neuroscientist 13: 109-114. (Pubitemid 46524315)
    • (2007) Neuroscientist , vol.13 , Issue.2 , pp. 109-114
    • Galve-Roperh, I.1    Aguado, T.2    Palazuelos, J.3    Guzman, M.4
  • 41
    • 76649137560 scopus 로고    scopus 로고
    • Loss of retrograde endocannabinoid signaling and reduced adult neurogenesis in diacylglycerol lipase knock-out mice
    • Gao Y, Vasilyev DV, Goncalves MB, Howell FV, Hobbs C, Reisenberg M, et al,. (2010). Loss of retrograde endocannabinoid signaling and reduced adult neurogenesis in diacylglycerol lipase knock-out mice. J Neurosci 30: 2017-2024.
    • (2010) J Neurosci , vol.30 , pp. 2017-2024
    • Gao, Y.1    Vasilyev, D.V.2    Goncalves, M.B.3    Howell, F.V.4    Hobbs, C.5    Reisenberg, M.6
  • 42
    • 33846066404 scopus 로고    scopus 로고
    • 9-Tetrahydrocannabinol protects hippocampal neurons from excitotoxicity
    • DOI 10.1016/j.brainres.2006.03.011, PII S0006899306007256
    • Gilbert GL, Kim HJ, Waataja JJ, Thayer SA, (2007). Delta9- tetrahydrocannabinol protects hippocampal neurons from excitotoxicity. Brain Res 1128: 61-69. (Pubitemid 46055239)
    • (2007) Brain Research , vol.1128 , Issue.1 , pp. 61-69
    • Gilbert, G.L.1    Kim, H.J.2    Waataja, J.J.3    Thayer, S.A.4
  • 43
    • 8844260491 scopus 로고    scopus 로고
    • Human brain endothelium: Coexpression and function of vanilloid and endocannabinoid receptors
    • DOI 10.1016/j.molbrainres.2004.08.025, PII S0169328X04004024
    • Golech SA, McCarron RM, Chen Y, Bembry J, Lenz F, Mechoulam R, et al,. (2004). Human brain endothelium: coexpression and function of vanilloid and endocannabinoid receptors. Brain Res Mol Brain Res 132: 87-92. (Pubitemid 39531355)
    • (2004) Molecular Brain Research , vol.132 , Issue.1 , pp. 87-92
    • Golech, S.A.1    McCarron, R.M.2    Chen, Y.3    Bembry, J.4    Lenz, F.5    Mechoulam, R.6    Shohami, E.7    Spatz, M.8
  • 44
    • 0033802583 scopus 로고    scopus 로고
    • Cannabinoids inhibit hippocampal GABAergic transmission and network oscillations
    • Hajos N, Katona I, Naiem SS, MacKie K, Ledent C, Mody I, et al,. (2000). Cannabinoids inhibit hippocampal GABAergic transmission and network oscillations. Eur J Neurosci 12: 3239-3249.
    • (2000) Eur J Neurosci , vol.12 , pp. 3239-3249
    • Hajos, N.1    Katona, I.2    Naiem, S.S.3    MacKie, K.4    Ledent, C.5    Mody, I.6
  • 45
    • 0035801320 scopus 로고    scopus 로고
    • Novel cannabinoid-sensitive receptor mediates inhibition of glutamatergic synaptic transmission in the hippocampus
    • DOI 10.1016/S0306-4522(01)00287-1, PII S0306452201002871
    • Hajos N, Ledent C, Freund TF, (2001). Novel cannabinoid-sensitive receptor mediates inhibition of glutamatergic synaptic transmission in the hippocampus. Neurosci 106: 1-4. (Pubitemid 32831068)
    • (2001) Neuroscience , vol.106 , Issue.1 , pp. 1-4
    • Hajos, N.1    Ledent, C.2    Freund, T.F.3
  • 46
    • 0024146867 scopus 로고
    • Pretreatment with phencyclidine, an N-methyl-D-aspartate antagonist, attenuates long-term behavioral deficits in the rat produced by traumatic brain injury
    • Hayes RL, Jenkins LW, Lyeth BG, Balster RL, Robinson SE, Clifton GL, et al,. (1988). Pretreatment with phencyclidine, an N-methyl-D-aspartate antagonist, attenuates long-term behavioral deficits in the rat produced by traumatic brain injury. J Neurotrauma 5: 259-274. (Pubitemid 19137963)
    • (1988) Journal of Neurotrauma , vol.5 , Issue.4 , pp. 259-274
    • Hayes, R.L.1    Jenkins, L.W.2    Lyeth, B.G.3    Balster, R.L.4    Robinson, S.E.5    Clifton, G.L.6    Stubbins, J.F.7    Young, H.F.8
  • 47
    • 77950692040 scopus 로고    scopus 로고
    • Enhancement of endocannabinoid signaling by fatty acid amide hydrolase inhibition: A neuroprotective therapeutic modality
    • Hwang J, Adamson C, Butler D, Janero DR, Makriyannis A, Bahr BA, (2010). Enhancement of endocannabinoid signaling by fatty acid amide hydrolase inhibition: a neuroprotective therapeutic modality. Life Sciences 86: 615-623.
    • (2010) Life Sciences , vol.86 , pp. 615-623
    • Hwang, J.1    Adamson, C.2    Butler, D.3    Janero, D.R.4    Makriyannis, A.5    Bahr, B.A.6
  • 48
    • 46849097142 scopus 로고    scopus 로고
    • NMDA receptors in clinical neurology: Excitatory times ahead
    • DOI 10.1016/S1474-4422(08)70165-0, PII S1474442208701650
    • Kalia LV, Kalia SK, Salter MW, (2008). NMDA receptors in clinical neurology: excitatory times ahead. Lancet Neurol 7: 742-755. (Pubitemid 351957932)
    • (2008) The Lancet Neurology , vol.7 , Issue.8 , pp. 742-755
    • Kalia, L.V.1    Kalia, S.K.2    Salter, M.W.3
  • 49
    • 23944432405 scopus 로고    scopus 로고
    • Dual modulation of endocannabinoid transport and fatty acid amide hydrolase protects against excitotoxicity
    • DOI 10.1523/JNEUROSCI.2347-05.2005
    • Karanian DA, Brown QB, Makriyannis A, Kosten TA, Bahr BA, (2005). Dual modulation of endocannabinoid transport and fatty acid amide hydrolase protects against excitotoxicity. J Neurosci 25: 7813-7820. (Pubitemid 41208653)
    • (2005) Journal of Neuroscience , vol.25 , Issue.34 , pp. 7813-7820
    • Karanian, D.A.1    Brown, Q.B.2    Makriyannis, A.3    Kosten, T.A.4    Bahr, B.A.5
  • 50
    • 0034084163 scopus 로고    scopus 로고
    • Phosphorylation meets ubiquitination: The control of NF-κB activity
    • DOI 10.1146/annurev.immunol.18.1.621
    • Karin M, Ben-Neriah Y, (2000). Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity. Annu Rev Immunol 18: 621-663. (Pubitemid 30365393)
    • (2000) Annual Review of Immunology , vol.18 , pp. 621-663
    • Karin, M.1    Ben-Neriah, Y.2
  • 52
    • 0035576023 scopus 로고    scopus 로고
    • Distribution of CB1 cannabinoid receptors in the amygdala and their role in the control of GABAergic transmission
    • Katona I, Rancz EA, Acsady L, Ledent C, Mackie K, Hajos N, et al,. (2001). Distribution of CB1 cannabinoid receptors in the amygdala and their role in the control of GABAergic transmission. J Neurosci 21: 9506-9518. (Pubitemid 33096895)
    • (2001) Journal of Neuroscience , vol.21 , Issue.23 , pp. 9506-9518
    • Katona, I.1    Rancz, E.A.2    Acsady, L.3    Ledent, C.4    Mackie, K.5    Hajos, N.6    Freund, T.F.7
  • 53
    • 79751524298 scopus 로고    scopus 로고
    • The cannabinoid WIN 55,212-2-mediated protection of dentate gyrus granule cells is driven by CB1 receptors and modulated by TRPA1 and Cav2.2 channels
    • [Epub ahead of print]
    • Koch M, Kreutz S, Böttger C, Grabiec U, Ghadban C, Korf HW, et al,. (2010). The cannabinoid WIN 55,212-2-mediated protection of dentate gyrus granule cells is driven by CB1 receptors and modulated by TRPA1 and Cav2.2 channels. Hippocampus [Epub ahead of print].
    • (2010) Hippocampus
    • Koch, M.1    Kreutz, S.2    Böttger, C.3    Grabiec, U.4    Ghadban, C.5    Korf, H.W.6
  • 54
    • 0036089438 scopus 로고    scopus 로고
    • Cerebral ischemia and trauma - Different etiologies yet similar mechanisms: Neuroprotective opportunities
    • DOI 10.1016/S0165-0173(02)00157-1, PII S0165017302001571
    • Leker RR, Shohami E, (2002). Cerebral ischemia and trauma-different etiologies yet similar mechanisms: neuroprotective opportunities. Brain Res Rev 39: 55-73. (Pubitemid 34666986)
    • (2002) Brain Research Reviews , vol.39 , Issue.1 , pp. 55-73
    • Leker, R.R.1    Shohami, E.2
  • 55
    • 0028004643 scopus 로고
    • Secondary mechanisms in neuronal trauma
    • Lynch DR, Dawson TM, (1994). Secondary mechanisms in neuronal trauma. Curr Opin Neurol 7: 510-516. (Pubitemid 24365662)
    • (1994) Current Opinion in Neurology , vol.7 , Issue.6 , pp. 510-516
    • Lynch, D.R.1    Dawson, T.M.2
  • 56
    • 33144480327 scopus 로고    scopus 로고
    • Cannabinoid receptors as therapeutic targets
    • Mackie K, (2006). Cannabinoid receptors as therapeutic targets. Annu Rev Pharmacol Toxicol 46: 101-122.
    • (2006) Annu Rev Pharmacol Toxicol , vol.46 , pp. 101-122
    • MacKie, K.1
  • 57
    • 77952731052 scopus 로고    scopus 로고
    • N-arachidonoyl glycine, an abundant endogenous lipid, potently drives directed cellular migration through GPR18, the putative abnormal cannabidiol receptor
    • McHugh D, Hu SS, Rimmerman N, Juknat A, Vogel Z, Walker JM, et al,. (2010). N-arachidonoyl glycine, an abundant endogenous lipid, potently drives directed cellular migration through GPR18, the putative abnormal cannabidiol receptor. BMC Neurosci 11: 44-58.
    • (2010) BMC Neurosci , vol.11 , pp. 44-58
    • McHugh, D.1    Hu, S.S.2    Rimmerman, N.3    Juknat, A.4    Vogel, Z.5    Walker, J.M.6
  • 59
    • 26844448746 scopus 로고    scopus 로고
    • 2 receptor in microglial cells in response to inflammatory stimuli
    • DOI 10.1111/j.1471-4159.2005.03380.x
    • Maresz K, Carrier EJ, Ponomarev ED, Hillard CJ, Dittel BN, (2005). Modulation of the cannabinoid CB2 receptor in microglial cells in response to inflammatory stimuli. J Neurochem 95: 437-445. (Pubitemid 41457512)
    • (2005) Journal of Neurochemistry , vol.95 , Issue.2 , pp. 437-445
    • Maresz, K.1    Carrier, E.J.2    Ponomarev, E.D.3    Hillard, C.J.4    Dittel, B.N.5
  • 61
    • 0029012014 scopus 로고
    • Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors
    • Mechoulam R, Ben-Shabat S, Hanus L, Ligumsky M, Kaminski NE, Schatz AR, et al,. (1995). Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors. Biochem Pharmacol 50: 83-90.
    • (1995) Biochem Pharmacol , vol.50 , pp. 83-90
    • Mechoulam, R.1    Ben-Shabat, S.2    Hanus, L.3    Ligumsky, M.4    Kaminski, N.E.5    Schatz, A.R.6
  • 62
    • 0032407065 scopus 로고    scopus 로고
    • Carbachol, an acetylcholine receptor agonist, enhances production in rat aorta of 2-arachidonoyl glycerol, a hypotensive endocannabinoid
    • DOI 10.1016/S0014-2999(98)00777-8, PII S0014299998007778
    • Mechoulam R, Fride E, Ben-Shabat S, Meiri U, Horowitz M, (1998). Carbachol, an acetylcholine receptor agonist, enhances production in rat aorta of 2-arachidonoyl glycerol, a hypotensive endocannabinoid. Eur J Pharmacol 362: R1-R3. (Pubitemid 29001003)
    • (1998) European Journal of Pharmacology , vol.362 , Issue.1
    • Mechoulam, R.1    Fride, E.2    Ben-Shabat, S.3    Meiri, U.4    Horowitz, M.5
  • 66
    • 71749104726 scopus 로고    scopus 로고
    • Cannabinoid receptors in brain: Pharmacogenetics, neuropharmacology, neurotoxicology, and potential therapeutic applications
    • Review
    • Onaivi ES, (2009). Cannabinoid receptors in brain: pharmacogenetics, neuropharmacology, neurotoxicology, and potential therapeutic applications. Int Rev Neurobiol 88: 335-369. Review.
    • (2009) Int Rev Neurobiol , vol.88 , pp. 335-369
    • Onaivi, E.S.1
  • 67
    • 34547484379 scopus 로고    scopus 로고
    • Regulation of PI3K/Akt/GSK-3 pathway by cannabinoids in the brain
    • DOI 10.1111/j.1471-4159.2007.04642.x
    • Ozaita A, Puighermanal E, Maldonado R, (2007). Regulation of PI3K/Akt/GSK-3 pathway by cannabinoids in the brain. J Neurochem 102: 1105-1114. (Pubitemid 47174245)
    • (2007) Journal of Neurochemistry , vol.102 , Issue.4 , pp. 1105-1114
    • Ozaita, A.1    Puighermanal, E.2    Maldonado, R.3
  • 68
    • 38349144914 scopus 로고    scopus 로고
    • Endocannabinoids and cannabinoid receptors in ischaemia reperfusion injury and preconditioning
    • Pacher P, Hasko G, (2008). Endocannabinoids and cannabinoid receptors in ischaemia reperfusion injury and preconditioning. Br J Pharmacol 153: 252-262.
    • (2008) Br J Pharmacol , vol.153 , pp. 252-262
    • Pacher, P.1    Hasko, G.2
  • 69
    • 33845603466 scopus 로고    scopus 로고
    • Non-psychoactive CB2 cannabinoid agonists stimulate neural progenitor proliferation
    • Palazuelos J, Aguado T, Egia A, Mechoulam R, Guzmán M, Galve-Roperh I, (2006). Non-psychoactive CB2 cannabinoid agonists stimulate neural progenitor proliferation. FASEB J 20: 2405-2407.
    • (2006) FASEB J , vol.20 , pp. 2405-2407
    • Palazuelos, J.1    Aguado, T.2    Egia, A.3    Mechoulam, R.4    Guzmán, M.5    Galve-Roperh, I.6
  • 70
    • 45149123400 scopus 로고    scopus 로고
    • The CB(2) cannabinoid receptor controls myeloid progenitor trafficking: Involvement in the pathogenesis of an animal model of multiple sclerosis
    • Palazuelos J, Davoust N, Julien B, Hatterer E, Aguado T, Mechoulam R, et al,. (2008). The CB(2) cannabinoid receptor controls myeloid progenitor trafficking: involvement in the pathogenesis of an animal model of multiple sclerosis. J Biol Chem 283: 13320-13329.
    • (2008) J Biol Chem , vol.283 , pp. 13320-13329
    • Palazuelos, J.1    Davoust, N.2    Julien, B.3    Hatterer, E.4    Aguado, T.5    Mechoulam, R.6
  • 73
    • 33646142292 scopus 로고    scopus 로고
    • The endocannabinoid 2-AG protects the blood brain barrier after closed head injury and inhibits expression of proinflammatory cytokines
    • Panikashvili D, Shein NA, Mechoulam R, Trembovler V, Kohen R, Alexandrovich A, et al,. (2006). The endocannabinoid 2-AG protects the blood brain barrier after closed head injury and inhibits expression of proinflammatory cytokines. Neurobiol Dis 22: 257-264.
    • (2006) Neurobiol Dis , vol.22 , pp. 257-264
    • Panikashvili, D.1    Shein, N.A.2    Mechoulam, R.3    Trembovler, V.4    Kohen, R.5    Alexandrovich, A.6
  • 74
    • 43949121784 scopus 로고    scopus 로고
    • Ligands that target cannabinoid receptors in the brain: From THC to anandamide and beyond
    • DOI 10.1111/j.1369-1600.2008.00108.x
    • Pertwee RG, (2008). Ligands that target cannabinoid receptors in the brain: from THC to anandamide and beyond. Addict Biol 13: 147-159. (Pubitemid 351698890)
    • (2008) Addiction Biology , vol.13 , Issue.2 , pp. 147-159
    • Pertwee, R.G.1
  • 75
    • 0242268553 scopus 로고    scopus 로고
    • The molecular logic of endocannabinoid signalling
    • DOI 10.1038/nrn1247
    • Piomelli D, (2003). The molecular logic of endocannabinoid signalling. Nat Rev Neurosci 4: 873-884. (Pubitemid 37351427)
    • (2003) Nature Reviews Neuroscience , vol.4 , Issue.11 , pp. 873-884
    • Piomelli, D.1
  • 77
    • 0031907160 scopus 로고    scopus 로고
    • Endocannabinoids: A new class of vasoactive substances
    • DOI 10.1016/S0165-6147(97)01161-9
    • Randall MD, Kendall DA, (1998). Endocannabinoids: a new class of vasoactive substances. J Trends Pharmacol Sci 19: 55-58. (Pubitemid 28137714)
    • (1998) Trends in Pharmacological Sciences , vol.19 , Issue.2 , pp. 55-58
    • Randall, M.D.1    Kendall, D.A.2
  • 78
    • 0035499974 scopus 로고    scopus 로고
    • Modulation of transmitter release via presynaptic cannabinoid receptors
    • DOI 10.1016/S0165-6147(00)01805-8, PII S0165614700018058
    • Schlicker E, Kathmann M, (2001). Modulation of transmitter release via presynaptic cannabinoid receptors. Trends Pharmacol Sci 22: 565-572. (Pubitemid 33042646)
    • (2001) Trends in Pharmacological Sciences , vol.22 , Issue.11 , pp. 565-572
    • Schlicker, E.1    Kathmann, M.2
  • 79
    • 0033995148 scopus 로고    scopus 로고
    • + M-current in hippocampal CA1 neurons
    • Schweitzer P, (2000). Cannabinoids decrease the K(+) M-current in hippocampal CA1 neurons. J Neurosci 20: 51-58. (Pubitemid 30220490)
    • (2000) Journal of Neuroscience , vol.20 , Issue.1 , pp. 51-58
    • Schweitzer, P.1
  • 80
    • 0031706164 scopus 로고    scopus 로고
    • Cannabinoid receptor agonists protect cultured rat hippocampal neurons from excitotoxicity
    • Shen M, Thayer SA, (1998). Cannabinoid receptor agonists protect cultured rat hippocampal neurons from excitotoxicity. Mol Pharmacol 54: 459-462. (Pubitemid 28442938)
    • (1998) Molecular Pharmacology , vol.54 , Issue.3 , pp. 459-462
    • Shen, M.1    Thayer, S.A.2
  • 81
    • 0029937282 scopus 로고    scopus 로고
    • Cannabinoid receptor agonists inhibit glutamatergic synaptic transmission in rat hippocampal cultures
    • Shen M, Piser TM, Seybold VS, Thayer SA, (1996). Cannabinoid receptor agonists inhibit glutamatergic synaptic transmission in rat hippocampal cultures. J Neurosci 16: 4322-4334. (Pubitemid 26243028)
    • (1996) Journal of Neuroscience , vol.16 , Issue.14 , pp. 4322-4334
    • Shen, M.1    Piser, T.M.2    Seybold, V.S.3    Thayer, S.A.4
  • 82
    • 0031047431 scopus 로고    scopus 로고
    • Cytokine production in the brain following closed head injury: Dexanabinol (HU-211) is a novel TNF-α inhibitor and an effective neuroprotectant
    • DOI 10.1016/S0165-5728(96)00181-6, PII S0165572896001816
    • Shohami E, Gallily R, Mechoulam R, Bass R, Ben-Hur T, (1997). Cytokine productionin the brain following closed head injury: Dexanabinol (HU-211) is a novel TNFα inhibitor and an effective neuroprotectant. J Neuroimmunol 72: 169-177. (Pubitemid 27062773)
    • (1997) Journal of Neuroimmunology , vol.72 , Issue.2 , pp. 169-177
    • Shohami, E.1    Gallily, R.2    Mechoulam, R.3    Bass, R.4    Ben-Hur, T.5
  • 83
    • 0032830106 scopus 로고    scopus 로고
    • Dual role of tumor necrosis factor alpha in brain injury
    • DOI 10.1016/S1359-6101(99)00008-8, PII S1359610199000088
    • Shohami E, Ginis I, Hallenbeck JM, (1999). Dual role of tumor necrosis factor alpha in brain injury. Cytokine Growth Factor Rev 10: 119-130. (Pubitemid 29446376)
    • (1999) Cytokine and Growth Factor Reviews , vol.10 , Issue.2 , pp. 119-130
    • Shohami, E.1    Ginis, I.2    Hallenbeck, J.M.3
  • 84
    • 0033988703 scopus 로고    scopus 로고
    • Endocannabinoids protect cerebral cortical neurons from in vitro ischemia in rats
    • DOI 10.1016/S0304-3940(99)00922-2, PII S0304394099009222
    • Sinor AD, Irvin SM, Greenberg DA, (2000). Endocannabinoids protect cerebral cortical neurons from in vitro ischemia in rats. Neurosci Lett 278: 157-160. (Pubitemid 30009481)
    • (2000) Neuroscience Letters , vol.278 , Issue.3 , pp. 157-160
    • Sinor, A.D.1    Irvin, S.M.2    Greenberg, D.A.3
  • 85
    • 43949146665 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors: 'Key' regulators of neuroinflammation after traumatic brain injury
    • Stahel PF, Smith WR, Bruchis J, Rabb CH, (2008). Peroxisome proliferator-activated receptors: 'key' regulators of neuroinflammation after traumatic brain injury. PPAR Res 2008: 538141.
    • (2008) PPAR Res , vol.2008 , pp. 538141
    • Stahel, P.F.1    Smith, W.R.2    Bruchis, J.3    Rabb, C.H.4
  • 86
    • 77954406421 scopus 로고    scopus 로고
    • Cannabinoid and cannabinoid-like receptors in microglia, astrocytes. and astrocytomas
    • Stella N, (2010). Cannabinoid and cannabinoid-like receptors in microglia, astrocytes. and astrocytomas. Glia 58: 1017-1030.
    • (2010) Glia , vol.58 , pp. 1017-1030
    • Stella, N.1
  • 88
    • 5444245546 scopus 로고    scopus 로고
    • Critical Appraisal of Neuroprotection Trials in Head Injury: What Have We Learned?
    • DOI 10.1602/neurorx.1.1.71, PII S1545534306700086
    • Tolias CM, Bullock MR, (2004). Critical appraisal of neuroprotection trials in head injury: what have we learned? NeuroRx 1: 71-79. (Pubitemid 46589341)
    • (2004) NeuroRx , vol.1 , Issue.1 , pp. 71-79
    • Tolias, C.M.1    Bullock, M.R.2
  • 89
    • 0031823187 scopus 로고    scopus 로고
    • Platelet- and macrophage-derived endogenous cannabinoids are involved in endotoxin-induced hypotension
    • Varga K, Wagner JA, Bridgen DT, Kunos G, (1998). Platelet- and macrophage-derived endogenous cannabinoids are involved in endotoxin-induced hypotension. FASEB J 12: 1035-1044. (Pubitemid 28359585)
    • (1998) FASEB Journal , vol.12 , Issue.11 , pp. 1035-1044
    • Varga, K.1    Wagner, J.A.2    Bridgen, D.T.3    Kunos, G.4
  • 90
    • 57849136110 scopus 로고    scopus 로고
    • Multifunctional drugs for head injury
    • Vink R, Nimmo AJ, (2009). Multifunctional drugs for head injury. Neurotherapeutics 6: 28-42.
    • (2009) Neurotherapeutics , vol.6 , pp. 28-42
    • Vink, R.1    Nimmo, A.J.2
  • 91
  • 92
    • 67649101330 scopus 로고    scopus 로고
    • Modulation of cannabinoid receptor activation as a neuroprotective strategy for EAE and stroke
    • Zhang M, Martin BR, Adler MW, Razdan RJ, Kong W, et al,. (2009). Modulation of cannabinoid receptor activation as a neuroprotective strategy for EAE and stroke. J Neuroimmine Pharmacol 4: 249-259.
    • (2009) J Neuroimmine Pharmacol , vol.4 , pp. 249-259
    • Zhang, M.1    Martin, B.R.2    Adler, M.W.3    Razdan, R.J.4    Kong, W.5
  • 93
    • 72949092495 scopus 로고    scopus 로고
    • Involvement of pro- and anti-inflammatory cytokines and chemokines in the pathophysiology of traumatic brain injury
    • Ziebell JM, Morganti-Kossmann MC, (2010). Involvement of pro- and anti-inflammatory cytokines and chemokines in the pathophysiology of traumatic brain injury. Neurotherap 7: 22-30.
    • (2010) Neurotherap , vol.7 , pp. 22-30
    • Ziebell, J.M.1    Morganti-Kossmann, M.C.2


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