Nitric oxide modulates endothelin 1-induced Ca2+ mobilization and cytoskeletal F-actin filaments in human cerebromicrovascular endothelial cells

Journal of Cerebral Blood Flow and Metabolism

Volumn 19, Issue 2, 1999, Pages 133-138

  Chen, Ye ^a   McCarron, Richard M ^b   Bembry, Joliet ^a   Ruetzler, Christi ^a   Azzam, Nabil ^a   Lenz, Fred A ^c   Spatz, Maria ^a  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^b NAVAL MEDICAL RESEARCH INSTITUTE   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Actin; Brain endothelial cells; Ca2+ Mobilization; cGMP Endothelin; Nitric oxide

Indexed keywords

CALCIUM; ENDOTHELIN 1; ENDOTHELIUM DERIVED CONSTRICTING FACTOR; F ACTIN; NITRIC OXIDE;

ACTIN FILAMENT; ARTICLE; BLOOD BRAIN BARRIER; BLOOD VESSEL TONE; BRAIN BLOOD VESSEL; BRAIN MICROCIRCULATION; CALCIUM MOBILIZATION; CELL CULTURE; ENDOTHELIUM CELL; FLUORESCENCE; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

EID: 0033029273     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004647-199902000-00003     Document Type: Article

References (28)

1. Bacic F, Uematsu S, McCarron RM, Spatz M (1992) Secretion of immunoreactive endothelin-1 by capillary and microvascular endothelium of human brain. Neurochem Res 17:699-702
2. Bakker ENTP, van der Linden PJW, Sipkema P (1997) Endothelin-1-induced constriction inhibits nitric-oxide-mediated dilation in isolated rat resistance arteries. J Vasc Res 34:418-424
3. Boulanger C, Luscher T (1990) Release of endothelin from the porcine aorta: inhibition by endothelin-derived nitric oxide. J Clin Invest 85:587-590
4. 2+ by atriopeptin and 8-bromo-cyclic GMP is mediated by cyclic GMP-dependent protein kinase. J Biol Chem 264:1146-1155
5. Durieu-Trautmann O, Federici C, Creminon C, Foignant-Cnaverot N, Roux F, Claire M, et al. (1993) Nitric oxide and endothelin secretion by brain microvessel endothelial cells: regulation by cyclic nucleotides. J Cell Physiol 155:104-111
6. Faire AL, Riesco A, Moliz M, Egido J, Casado S, Hemando L, et al. (1991) Inhibition by L-arginine of the endothelin-mediated in-crease in cytosolic calcium in human neutrophils. Biochem Biophys Res Commun 178:884-891
7. Gellai M, De Wolf R, Fletcher T, Nambi P (1997) Contribution of endogenous endothelin-1 to the maintenance of vascular tone: role of nitric oxide. Pharmacology 55:299-308
8. Goligorsky MA, Tsukahara H, Magazine H, Andersen TT, Malik AB, Bahou WF (1994) Termination of endothelin signaling: role of nitric oxide. J Cell Physiol 158:485-494
9. Hall A (1998) G proteins and small GTPases: distant relatives keep in touch. Science 280:2074-2075
10. MacCumber MW, Ross AC, Snyder SH (1990) Endothelin in the brain: receptors, mitogenesis, and biosynthesis in glial cells. Proc Natl Acad Sci USA 87:2359-2363
11. MacMillan-Crow LA, Lincoln TM (1994) High-affinity binding and localization of the cyclic GMP-dependent protein kinase with the intermediate filament protein vimentin. Biochemistry 33:8035-8043
12. Masaki T (1994) Endothelin in vascular biology. Ann NY Acad Sci 714:101-108
13. Molitoris B A, Leiser J, Wagner MC (1997) Role of the actin cytoskeleton in ischemia-induced cell and repair. Pediatr Nephrol 11:761-767
14. Moncada S, Palmer RM, Higgs EA (1991) Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol Rev 43:109-142
15. 2+ mobilization in rat vascular smooth muscle cells. Biochem Biophys Res Commun 183:849-855
16. Pryzwansky KB, Wyatt TA, Lincoln TM (1995) Cyclic guanosine monophosphate-dependent protein kinase is targeted to intermediate filaments and phosphorylates vimentin in A23187-stimulated human neutrophils. Blood 85:222-230
17. Rasmussen H (1983) Cellular calcium metabolism. Ann Intern Med 98:809-816
18. Reinhard M, Halbrugge M, Scheer U, Wiegand C, Jockusch BM, Walter U (1992) The 46/50 kDa phosphoprotein VASP purified from human platelets is a novel protein associated with actin filaments and focal contacts. EMBO J 11:2063-2070
19. Riesco A, Caramelo C, Blum G, Monton M, Gallego MJ, Casado S, et al. (1993) Nitric oxide-generating system as an autocrine mechanism in human polymorphonuclear leucocytes. Biochem J 292:791-796
20. Saijonmaa O, Ristimaki A, Fyhrquist F (1990) Atrial natriuretic peptide, nitroglycerine, and nitroprusside reduce basal and stimulated endothelin production from cultured endothelial cells. Biochem Biophys Res Commun 173:514-520
21. Schmidt HHHW, Lohmann SM, Walter U (1993) The nitric oxide and cGMP signal transduction system: regulation and mechanism of action. Biochem Biophys Acta 1178:153-175
22. Spatz M, Yasuma Y, Strasser A, McCarron RM (1996) Cerebral postischemic hypoperfusion is mediated by ETA receptors. Brain Res 726:242-246
23. Spatz M, Kawai N, Merkel N, Bembry J, McCarron RM (1997a) Functional properties of cultured endothelial cells derived from large microvessels of human brain. Am J Physiol 272:C231-C239
24. Spatz M, Yamamoto H, Yamamoto T, McCarron RM ( 19976) Effect of nitric oxide donors on ET-1 binding sites in human cerebrovascular endothelium. J Cereb Blood Flow Metab 17:5397
25. Thorin E, Cernacek P, Dupuis J (1998) Endothelin-1 regulates tone of isolated small arteries in the rat: effect of hyperendothelinmia. Hypertension 31:1035-1041
26. Vane JR, Bolting RM (1994) Mediators from the endothelial cell and their participation in inflammation. Int J Tissue Reac 16:19-49
27. Walsh MP, Kargacin GJ, Kendrick-Jones J, Lincoln TM (1995) Intracellular mechanisms involved in the regulation of vascular smooth muscle tone. Can J Physiol Pharmacol 73:565-573
28. Yanagisawa M, Kurihara H, Kimura S, Tomobe Y, Kobayashi M, Mitsui Y, et al. (1988) A novel potent vasoconstrictive peptide produced by endothelial cells. Nature 332:411-415