메뉴 건너뛰기




Volumn 7, Issue 1, 2010, Pages 22-30

Involvement of Pro- and Anti-Inflammatory Cytokines and Chemokines in the Pathophysiology of Traumatic Brain Injury

Author keywords

chemokines; cytokines; human TBI; Inflammation; traumatic brain injury

Indexed keywords

CHEMOKINE; CORTICOSTEROID; CYTOKINE; DEXANABINOL; ERYTHROPOIETIN; FAS LIGAND; GRANULOCYTE COLONY STIMULATING FACTOR; IBUPROFEN; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 10; INTERLEUKIN 6; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 2; MINOCYCLINE; MONOCYTE CHEMOTACTIC PROTEIN 1; NONSTEROID ANTIINFLAMMATORY AGENT; PENTOXIFYLLINE; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR BINDING PROTEIN;

EID: 72949092495     PISSN: 19337213     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nurt.2009.10.016     Document Type: Article
Times cited : (560)

References (100)
  • 1
    • 2442687858 scopus 로고    scopus 로고
    • Cell death mechanisms following traumatic brain injury
    • Raghupathi R. Cell death mechanisms following traumatic brain injury. Brain Pathol 14 (2004) 215-222
    • (2004) Brain Pathol , vol.14 , pp. 215-222
    • Raghupathi, R.1
  • 2
    • 0035462607 scopus 로고    scopus 로고
    • Role of cerebral inflammation after traumatic brain injury: a revisited concept
    • Morganti-Kossmann M.C., Rancan M., Otto V.I., Stahel P.F., and Kossmann T. Role of cerebral inflammation after traumatic brain injury: a revisited concept. Shock 16 (2001) 165-177
    • (2001) Shock , vol.16 , pp. 165-177
    • Morganti-Kossmann, M.C.1    Rancan, M.2    Otto, V.I.3    Stahel, P.F.4    Kossmann, T.5
  • 3
    • 12744260011 scopus 로고    scopus 로고
    • The neuroprotective role of inflammation in nervous system injuries
    • Correale J., and Villa A. The neuroprotective role of inflammation in nervous system injuries. J Neurol 251 (2004) 1304-1316
    • (2004) J Neurol , vol.251 , pp. 1304-1316
    • Correale, J.1    Villa, A.2
  • 4
    • 33847261481 scopus 로고    scopus 로고
    • Transient neuroprotection by minocycline following traumatic brain injury is associated with attenuated microglial activation but no changes in cell apoptosis or neutrophil infiltration
    • Bye N., Habgood M.D., Callaway J.K., et al. Transient neuroprotection by minocycline following traumatic brain injury is associated with attenuated microglial activation but no changes in cell apoptosis or neutrophil infiltration. Exp Neurol 204 (2007) 220-233
    • (2007) Exp Neurol , vol.204 , pp. 220-233
    • Bye, N.1    Habgood, M.D.2    Callaway, J.K.3
  • 5
    • 0031814850 scopus 로고    scopus 로고
    • The Dorothy Russell Memorial Lecture. The molecular and cellular sequelae of experimental traumatic brain injury: pathogenetic mechanisms
    • McIntosh T.K., Saatman K.E., Raghupathi R., et al. The Dorothy Russell Memorial Lecture. The molecular and cellular sequelae of experimental traumatic brain injury: pathogenetic mechanisms. Neuropathol Appl Neurobiol 24 (1998) 251-267
    • (1998) Neuropathol Appl Neurobiol , vol.24 , pp. 251-267
    • McIntosh, T.K.1    Saatman, K.E.2    Raghupathi, R.3
  • 6
    • 0027945338 scopus 로고
    • Neutrophil accumulation after traumatic brain injury in rats: comparison of weight drop and controlled cortical impact models
    • Clark R.S., Schiding J.K., Kaczorowski S.L., Marion D.W., and Kochanek P.M. Neutrophil accumulation after traumatic brain injury in rats: comparison of weight drop and controlled cortical impact models. J Neurotrauma 11 (1994) 499-506
    • (1994) J Neurotrauma , vol.11 , pp. 499-506
    • Clark, R.S.1    Schiding, J.K.2    Kaczorowski, S.L.3    Marion, D.W.4    Kochanek, P.M.5
  • 7
    • 0033977381 scopus 로고    scopus 로고
    • The initiation of the microglial response
    • Kato H., and Walz W. The initiation of the microglial response. Brain Pathol 10 (2000) 137-143
    • (2000) Brain Pathol , vol.10 , pp. 137-143
    • Kato, H.1    Walz, W.2
  • 8
    • 0033977380 scopus 로고    scopus 로고
    • Leukocyte recruitment and the acute inflammatory response
    • Kubes P., and Ward P.A. Leukocyte recruitment and the acute inflammatory response. Brain Pathol 10 (2000) 127-135
    • (2000) Brain Pathol , vol.10 , pp. 127-135
    • Kubes, P.1    Ward, P.A.2
  • 10
    • 34447527791 scopus 로고    scopus 로고
    • Pathophysiology of traumatic brain injury
    • Werner C., and Engelhard K. Pathophysiology of traumatic brain injury. Br J Anaesth 99 (2007) 4-9
    • (2007) Br J Anaesth , vol.99 , pp. 4-9
    • Werner, C.1    Engelhard, K.2
  • 11
    • 30444459031 scopus 로고    scopus 로고
    • The role of inflammation in CNS injury and disease
    • Lucas S.M., Rothwell N.J., and Gibson R.M. The role of inflammation in CNS injury and disease. Br J Pharmacol 147 Suppl 1 (2006) S232-S240
    • (2006) Br J Pharmacol , vol.147 , Issue.SUPPL. 1
    • Lucas, S.M.1    Rothwell, N.J.2    Gibson, R.M.3
  • 12
    • 0030222037 scopus 로고    scopus 로고
    • Microglia: a sensor for pathological events in the CNS
    • Kreutzberg G.W. Microglia: a sensor for pathological events in the CNS. Trends Neurosci 19 (1996) 312-318
    • (1996) Trends Neurosci , vol.19 , pp. 312-318
    • Kreutzberg, G.W.1
  • 13
    • 0033152442 scopus 로고    scopus 로고
    • Leukocyte infiltration, neuronal degeneration, and neurite outgrowth after ablation of scar-forming, reactive astrocytes in adult transgenic mice
    • Bush T.G., Puvanachandra N., Horner C.H., et al. Leukocyte infiltration, neuronal degeneration, and neurite outgrowth after ablation of scar-forming, reactive astrocytes in adult transgenic mice. Neuron 23 (1999) 297-308
    • (1999) Neuron , vol.23 , pp. 297-308
    • Bush, T.G.1    Puvanachandra, N.2    Horner, C.H.3
  • 14
    • 0026568658 scopus 로고
    • Breakdown of the blood-brain barrier after fluid percussive brain injury in the rat. Part 1: Distribution and time course of protein extravasation
    • Tanno H., Nockels R.P., Pitts L.H., and Noble L.J. Breakdown of the blood-brain barrier after fluid percussive brain injury in the rat. Part 1: Distribution and time course of protein extravasation. J Neurotrauma 9 (1992) 21-32
    • (1992) J Neurotrauma , vol.9 , pp. 21-32
    • Tanno, H.1    Nockels, R.P.2    Pitts, L.H.3    Noble, L.J.4
  • 15
    • 33846216899 scopus 로고    scopus 로고
    • Changes in blood-brain barrier permeability to large and small molecules following traumatic brain injury in mice
    • Habgood M.D., Bye N., Dziegielewska K.M., et al. Changes in blood-brain barrier permeability to large and small molecules following traumatic brain injury in mice. Eur J Neurosci 25 (2007) 231-238
    • (2007) Eur J Neurosci , vol.25 , pp. 231-238
    • Habgood, M.D.1    Bye, N.2    Dziegielewska, K.M.3
  • 16
    • 0032950857 scopus 로고    scopus 로고
    • Annual review prize lecture. Cytokines: killers in the brain?
    • Rothwell N.J. Annual review prize lecture. Cytokines: killers in the brain?. J Physiol 514 (1999) 3-17
    • (1999) J Physiol , vol.514 , pp. 3-17
    • Rothwell, N.J.1
  • 17
    • 0036063103 scopus 로고    scopus 로고
    • Involvement of inflammatory cytokines in central nervous system injury
    • Wang C.X., and Shuaib A. Involvement of inflammatory cytokines in central nervous system injury. Prog Neurobiol 67 (2002) 161-172
    • (2002) Prog Neurobiol , vol.67 , pp. 161-172
    • Wang, C.X.1    Shuaib, A.2
  • 19
    • 0033870421 scopus 로고    scopus 로고
    • Proinflammatory cytokine, chemokine, and cellular adhesion molecule expression during the acute phase of experimental brain abscess development
    • Kielian T., and Hickey W.F. Proinflammatory cytokine, chemokine, and cellular adhesion molecule expression during the acute phase of experimental brain abscess development. Am J Pathol 157 (2000) 647-658
    • (2000) Am J Pathol , vol.157 , pp. 647-658
    • Kielian, T.1    Hickey, W.F.2
  • 20
    • 77649272361 scopus 로고    scopus 로고
    • Role of chemokines in CNS health and pathology: a focus on the CCL2/CCR2 and CXCL8/CXCR2 networks
    • [Epub ahead of print]
    • Semple B.D., Kossmann T., and Morganti-Kossmann M.C. Role of chemokines in CNS health and pathology: a focus on the CCL2/CCR2 and CXCL8/CXCR2 networks. J Cereb Blood Flow Metab (2009 Nov 11) [Epub ahead of print]
    • (2009) J Cereb Blood Flow Metab
    • Semple, B.D.1    Kossmann, T.2    Morganti-Kossmann, M.C.3
  • 22
    • 0028788688 scopus 로고
    • Mapping of receptor binding sites on IL-1β by reconstruction of IL-1ra-like domains
    • Boraschi D., Bossù P., Ruggiero P., et al. Mapping of receptor binding sites on IL-1β by reconstruction of IL-1ra-like domains. J Immunol 155 (1995) 4719-4725
    • (1995) J Immunol , vol.155 , pp. 4719-4725
    • Boraschi, D.1    Bossù, P.2    Ruggiero, P.3
  • 23
    • 0037107017 scopus 로고    scopus 로고
    • A microdialysis method for the recovery of IL-1β, IL-6 and nerve growth factor from human brain in vivo
    • Winter C.D., Iannotti F., Pringle A.K., Trikkas C., Clough G.F., and Church M.K. A microdialysis method for the recovery of IL-1β, IL-6 and nerve growth factor from human brain in vivo. J Neurosci Methods 119 (2002) 45-50
    • (2002) J Neurosci Methods , vol.119 , pp. 45-50
    • Winter, C.D.1    Iannotti, F.2    Pringle, A.K.3    Trikkas, C.4    Clough, G.F.5    Church, M.K.6
  • 24
    • 0025820808 scopus 로고
    • Detection of interleukin-1 and interleukin-6 in adult rat brain, following mechanical injury, by in vivo microdialysis: evidence of a role for microglia in cytokine production
    • Woodroofe M.N., Sarna G.S., Wadhwa M., et al. Detection of interleukin-1 and interleukin-6 in adult rat brain, following mechanical injury, by in vivo microdialysis: evidence of a role for microglia in cytokine production. J Neuroimmunol 33 (1991) 227-236
    • (1991) J Neuroimmunol , vol.33 , pp. 227-236
    • Woodroofe, M.N.1    Sarna, G.S.2    Wadhwa, M.3
  • 25
    • 0034726016 scopus 로고    scopus 로고
    • Cortical interleukin-1β elevation after traumatic brain injury in the rat: no effect of two selective antagonists on motor recovery
    • Knoblach S.M., and Faden A.I. Cortical interleukin-1β elevation after traumatic brain injury in the rat: no effect of two selective antagonists on motor recovery. Neurosci Lett 289 (2000) 5-8
    • (2000) Neurosci Lett , vol.289 , pp. 5-8
    • Knoblach, S.M.1    Faden, A.I.2
  • 26
    • 0029744418 scopus 로고    scopus 로고
    • Neuroprotective effects of human recombinant interleukin-1 receptor antagonist in focal cerebral ischaemia in the rat
    • Loddick S.A., and Rothwell N.J. Neuroprotective effects of human recombinant interleukin-1 receptor antagonist in focal cerebral ischaemia in the rat. J Cereb Blood Flow Metab 16 (1996) 932-940
    • (1996) J Cereb Blood Flow Metab , vol.16 , pp. 932-940
    • Loddick, S.A.1    Rothwell, N.J.2
  • 27
    • 0026656192 scopus 로고
    • Interleukin-1 receptor antagonist inhibits ischaemic and excitotoxic neuronal damage in the rat
    • Relton J.K., and Rothwell N.J. Interleukin-1 receptor antagonist inhibits ischaemic and excitotoxic neuronal damage in the rat. Brain Res Bull 29 (1992) 243-246
    • (1992) Brain Res Bull , vol.29 , pp. 243-246
    • Relton, J.K.1    Rothwell, N.J.2
  • 28
    • 62949095938 scopus 로고    scopus 로고
    • The genomic profile of the cerebral cortex after closed head injury in mice: effects of minocycline
    • Crack P.J., Gould J., Bye N., et al. The genomic profile of the cerebral cortex after closed head injury in mice: effects of minocycline. J Neural Transm 116 (2009) 1-12
    • (2009) J Neural Transm , vol.116 , pp. 1-12
    • Crack, P.J.1    Gould, J.2    Bye, N.3
  • 29
    • 0034998271 scopus 로고    scopus 로고
    • Minocycline reduces traumatic brain injury-mediated caspase-1 activation, tissue damage, and neurological dysfunction
    • discussion 1399-1401
    • Sanchez Mejia R.O., Ona V.O., Li M., and Friedlander R.M. Minocycline reduces traumatic brain injury-mediated caspase-1 activation, tissue damage, and neurological dysfunction. Neurosurgery 48 (2001) 1393-1399 discussion 1399-1401
    • (2001) Neurosurgery , vol.48 , pp. 1393-1399
    • Sanchez Mejia, R.O.1    Ona, V.O.2    Li, M.3    Friedlander, R.M.4
  • 30
    • 0028587318 scopus 로고
    • Structure-function analysis of human IL-6: identification of two distinct regions that are important for receptor binding
    • Hammacher A., Ward L.D., Weinstock J., Treutlein H., Yasukawa K., and Simpson R.J. Structure-function analysis of human IL-6: identification of two distinct regions that are important for receptor binding. Protein Sci 3 (1994) 2280-2293
    • (1994) Protein Sci , vol.3 , pp. 2280-2293
    • Hammacher, A.1    Ward, L.D.2    Weinstock, J.3    Treutlein, H.4    Yasukawa, K.5    Simpson, R.J.6
  • 31
    • 0032814562 scopus 로고    scopus 로고
    • Neuroglial activation repertoire in the injured brain: graded response, molecular mechanisms and cues to physiological function
    • Raivich G., Bohatschek M., Kloss C.U., Werner A., Jones L.L., and Kreutzberg G.W. Neuroglial activation repertoire in the injured brain: graded response, molecular mechanisms and cues to physiological function. Brain Res Brain Res Rev 30 (1999) 77-105
    • (1999) Brain Res Brain Res Rev , vol.30 , pp. 77-105
    • Raivich, G.1    Bohatschek, M.2    Kloss, C.U.3    Werner, A.4    Jones, L.L.5    Kreutzberg, G.W.6
  • 32
    • 0028800715 scopus 로고
    • Cytokines and the nervous system. I: Expression and recognition
    • Hopkins S.J., and Rothwell N.J. Cytokines and the nervous system. I: Expression and recognition. Trends Neurosci 18 (1995) 83-88
    • (1995) Trends Neurosci , vol.18 , pp. 83-88
    • Hopkins, S.J.1    Rothwell, N.J.2
  • 33
    • 0345580623 scopus 로고    scopus 로고
    • Cytokine actions in the central nervous system
    • Benveniste E.N. Cytokine actions in the central nervous system. Cytokine Growth Factor Rev 9 (1998) 259-275
    • (1998) Cytokine Growth Factor Rev , vol.9 , pp. 259-275
    • Benveniste, E.N.1
  • 34
    • 0029398824 scopus 로고
    • Intrathecal and serum interleukin-6 and the acute-phase response in patients with severe traumatic brain injuries
    • Kossmann T., Hans V.H., Imhof H.G., et al. Intrathecal and serum interleukin-6 and the acute-phase response in patients with severe traumatic brain injuries. Shock 4 (1995) 311-317
    • (1995) Shock , vol.4 , pp. 311-317
    • Kossmann, T.1    Hans, V.H.2    Imhof, H.G.3
  • 35
    • 0028364659 scopus 로고
    • Closed head injury triggers early production of TNFα and IL-6 by brain tissue
    • Shohami E., Novikov M., Bass R., Yamin A., and Gallily R. Closed head injury triggers early production of TNFα and IL-6 by brain tissue. J Cereb Blood Flow Metab 14 (1994) 615-619
    • (1994) J Cereb Blood Flow Metab , vol.14 , pp. 615-619
    • Shohami, E.1    Novikov, M.2    Bass, R.3    Yamin, A.4    Gallily, R.5
  • 36
    • 0027400847 scopus 로고
    • Increase in IL-6, IL-1 and TNF levels in rat brain following traumatic lesion: influence of pre- and post-traumatic treatment with Ro5 4864, a peripheral-type (p site) benzodiazepine ligand
    • Taupin V., Toulmond S., Serrano A., Benavides J., and Zavala F. Increase in IL-6, IL-1 and TNF levels in rat brain following traumatic lesion: influence of pre- and post-traumatic treatment with Ro5 4864, a peripheral-type (p site) benzodiazepine ligand. J Neuroimmunol 42 (1993) 177-185
    • (1993) J Neuroimmunol , vol.42 , pp. 177-185
    • Taupin, V.1    Toulmond, S.2    Serrano, A.3    Benavides, J.4    Zavala, F.5
  • 37
    • 0041620549 scopus 로고    scopus 로고
    • Astrocyte-targeted expression of interleukin-6 protects the central nervous system during neuroglial degeneration induced by 6-aminonicotinamide
    • Penkowa M., Camats J., Hadberg H., et al. Astrocyte-targeted expression of interleukin-6 protects the central nervous system during neuroglial degeneration induced by 6-aminonicotinamide. J Neurosci Res 73 (2003) 481-496
    • (2003) J Neurosci Res , vol.73 , pp. 481-496
    • Penkowa, M.1    Camats, J.2    Hadberg, H.3
  • 38
    • 0033667998 scopus 로고    scopus 로고
    • Impaired inflammatory response and increased oxidative stress and neurodegeneration after brain injury in interleukin-6-deficient mice
    • Penkowa M., Giralt M., Carrasco J., Hadberg H., and Hidalgo J. Impaired inflammatory response and increased oxidative stress and neurodegeneration after brain injury in interleukin-6-deficient mice. Glia 32 (2000) 271-285
    • (2000) Glia , vol.32 , pp. 271-285
    • Penkowa, M.1    Giralt, M.2    Carrasco, J.3    Hadberg, H.4    Hidalgo, J.5
  • 40
    • 0033564234 scopus 로고    scopus 로고
    • 2 on tumor necrosis factor and interleukin-10 production in microglia: a regulatory loop controlling microglia pro- and anti-inflammatory activities
    • 2 on tumor necrosis factor and interleukin-10 production in microglia: a regulatory loop controlling microglia pro- and anti-inflammatory activities. J Neurosci Res 56 (1999) 571-580
    • (1999) J Neurosci Res , vol.56 , pp. 571-580
    • Aloisi, F.1    De Simone, R.2    Columba-Cabezas, S.3    Levi, G.4
  • 41
    • 0037436514 scopus 로고    scopus 로고
    • Effects of interleukin-10 on neonatal excitotoxic brain lesions in mice
    • Mesples B., Plaisant F., and Gressens P. Effects of interleukin-10 on neonatal excitotoxic brain lesions in mice. Brain Res Dev Brain Res 141 (2003) 25-32
    • (2003) Brain Res Dev Brain Res , vol.141 , pp. 25-32
    • Mesples, B.1    Plaisant, F.2    Gressens, P.3
  • 42
    • 24144448083 scopus 로고    scopus 로고
    • Leptomeningeal cells activate microglia and astrocytes to induce IL-10 production by releasing pro-inflammatory cytokines during systemic inflammation
    • Wu Z., Zhang J., and Nakanishi H. Leptomeningeal cells activate microglia and astrocytes to induce IL-10 production by releasing pro-inflammatory cytokines during systemic inflammation. J Neuroimmunol 167 (2005) 90-98
    • (2005) J Neuroimmunol , vol.167 , pp. 90-98
    • Wu, Z.1    Zhang, J.2    Nakanishi, H.3
  • 43
    • 0031713714 scopus 로고    scopus 로고
    • Interleukin-10 improves outcome and alters proinflammatory cytokine expression after experimental traumatic brain injury
    • Knoblach S.M., and Faden A.I. Interleukin-10 improves outcome and alters proinflammatory cytokine expression after experimental traumatic brain injury. Exp Neurol 153 (1998) 143-151
    • (1998) Exp Neurol , vol.153 , pp. 143-151
    • Knoblach, S.M.1    Faden, A.I.2
  • 44
    • 17044373214 scopus 로고    scopus 로고
    • Interleukin-10 inhibits endotoxin-induced pro-inflammatory cytokines in microglial cell cultures
    • Kremlev S.G., and Palmer C. Interleukin-10 inhibits endotoxin-induced pro-inflammatory cytokines in microglial cell cultures. J Neuroimmunol 162 (2005) 71-80
    • (2005) J Neuroimmunol , vol.162 , pp. 71-80
    • Kremlev, S.G.1    Palmer, C.2
  • 45
    • 0032752147 scopus 로고    scopus 로고
    • IL-10 levels in cerebrospinal fluid and serum of patients with severe traumatic brain injury: relationship to IL-6, TNF-α, TGF-β1 and blood-brain barrier function
    • Csuka E., Morganti-Kossmann M.C., Lenzlinger P.M., Joller H., Trentz O., and Kossmann T. IL-10 levels in cerebrospinal fluid and serum of patients with severe traumatic brain injury: relationship to IL-6, TNF-α, TGF-β1 and blood-brain barrier function. J Neuroimmunol 101 (1999) 211-221
    • (1999) J Neuroimmunol , vol.101 , pp. 211-221
    • Csuka, E.1    Morganti-Kossmann, M.C.2    Lenzlinger, P.M.3    Joller, H.4    Trentz, O.5    Kossmann, T.6
  • 46
    • 17844407448 scopus 로고    scopus 로고
    • Effect of interleukin-10 on newborn piglet brain following hypoxia-ischemia and endotoxin-induced inflammation
    • Lyng K., Munkeby B.H., Saugstad O.D., Stray-Pedersen B., and Frøen J.F. Effect of interleukin-10 on newborn piglet brain following hypoxia-ischemia and endotoxin-induced inflammation. Biol Neonate 87 (2005) 207-216
    • (2005) Biol Neonate , vol.87 , pp. 207-216
    • Lyng, K.1    Munkeby, B.H.2    Saugstad, O.D.3    Stray-Pedersen, B.4    Frøen, J.F.5
  • 47
    • 0030833724 scopus 로고    scopus 로고
    • Interleukin-6 and interleukin-10 in cerebrospinal fluid after severe traumatic brain injury in children
    • Bell M.J., Kochanek P.M., Doughty L.A., et al. Interleukin-6 and interleukin-10 in cerebrospinal fluid after severe traumatic brain injury in children. J Neurotrauma 14 (1997) 451-457
    • (1997) J Neurotrauma , vol.14 , pp. 451-457
    • Bell, M.J.1    Kochanek, P.M.2    Doughty, L.A.3
  • 48
    • 0027483753 scopus 로고
    • Distribution and characterization of tumor necrosis factor-α-like immunoreactivity in the murine central nervous system
    • Breder C.D., Tsujimoto M., Terano Y., Scott D.W., and Saper C.B. Distribution and characterization of tumor necrosis factor-α-like immunoreactivity in the murine central nervous system. J Comp Neurol 337 (1993) 543-567
    • (1993) J Comp Neurol , vol.337 , pp. 543-567
    • Breder, C.D.1    Tsujimoto, M.2    Terano, Y.3    Scott, D.W.4    Saper, C.B.5
  • 49
    • 0035487313 scopus 로고    scopus 로고
    • Cytokines and acute neurodegeneration
    • Allan S.M., and Rothwell N.J. Cytokines and acute neurodegeneration. Nat Rev Neurosci 2 (2001) 734-744
    • (2001) Nat Rev Neurosci , vol.2 , pp. 734-744
    • Allan, S.M.1    Rothwell, N.J.2
  • 50
    • 0029620390 scopus 로고
    • Interleukin-1 and tumor necrosis factor-α synergistically mediate neurotoxicity: involvement of nitric oxide and of N-methyl-d-aspartate receptors
    • Chao C.C., Hu S., Ehrlich L., and Peterson P.K. Interleukin-1 and tumor necrosis factor-α synergistically mediate neurotoxicity: involvement of nitric oxide and of N-methyl-d-aspartate receptors. Brain Behav Immun 9 (1995) 355-365
    • (1995) Brain Behav Immun , vol.9 , pp. 355-365
    • Chao, C.C.1    Hu, S.2    Ehrlich, L.3    Peterson, P.K.4
  • 51
    • 0031047431 scopus 로고    scopus 로고
    • Cytokine production in the brain following closed head injury: dexanabinol (HU-211) is a novel TNF-α inhibitor and an effective neuroprotectant
    • Shohami E., Gallily R., Mechoulam R., Bass R., and Ben-Hur T. Cytokine production in the brain following closed head injury: dexanabinol (HU-211) is a novel TNF-α inhibitor and an effective neuroprotectant. J Neuroimmunol 72 (1997) 169-177
    • (1997) J Neuroimmunol , vol.72 , pp. 169-177
    • Shohami, E.1    Gallily, R.2    Mechoulam, R.3    Bass, R.4    Ben-Hur, T.5
  • 52
    • 0027969064 scopus 로고
    • Contribution of peripheral macrophages and microglia to the cellular reaction after mechanical or neurotoxin-induced lesions of the rat brain
    • Riva-Depaty I., Fardeau C., Mariani J., Bouchaud C., and Delhaye-Bouchaud N. Contribution of peripheral macrophages and microglia to the cellular reaction after mechanical or neurotoxin-induced lesions of the rat brain. Exp Neurol 128 (1994) 77-87
    • (1994) Exp Neurol , vol.128 , pp. 77-87
    • Riva-Depaty, I.1    Fardeau, C.2    Mariani, J.3    Bouchaud, C.4    Delhaye-Bouchaud, N.5
  • 53
  • 54
    • 0033103686 scopus 로고    scopus 로고
    • Early neuronal expression of tumor necrosis factor-α after experimental brain injury contributes to neurological impairment
    • Knoblach S.M., Fan L., and Faden A.I. Early neuronal expression of tumor necrosis factor-α after experimental brain injury contributes to neurological impairment. J Neuroimmunol 95 (1999) 115-125
    • (1999) J Neuroimmunol , vol.95 , pp. 115-125
    • Knoblach, S.M.1    Fan, L.2    Faden, A.I.3
  • 55
    • 0027049701 scopus 로고
    • Modulation of blood-brain barrier permeability by tumor necrosis factor and antibody to tumor necrosis factor in the rat
    • Kim K.S., Wass C.A., Cross A.S., and Opal S.M. Modulation of blood-brain barrier permeability by tumor necrosis factor and antibody to tumor necrosis factor in the rat. Lymphokine Cytokine Res 11 (1992) 293-298
    • (1992) Lymphokine Cytokine Res , vol.11 , pp. 293-298
    • Kim, K.S.1    Wass, C.A.2    Cross, A.S.3    Opal, S.M.4
  • 56
    • 0025078410 scopus 로고
    • Tumor necrosis factor α/cachectin and interleukin 1 β initiate meningeal inflammation
    • Ramilo O., Sáez-Llorens X., Mertsola J., et al. Tumor necrosis factor α/cachectin and interleukin 1 β initiate meningeal inflammation. J Exp Med 172 (1990) 497-507
    • (1990) J Exp Med , vol.172 , pp. 497-507
    • Ramilo, O.1    Sáez-Llorens, X.2    Mertsola, J.3
  • 57
    • 29044436727 scopus 로고    scopus 로고
    • Efficacy and safety of dexanabinol in severe traumatic brain injury: results of a phase III randomised, placebo-controlled, clinical trial
    • Maas A.I., Murray G., Henney III H., et al. Efficacy and safety of dexanabinol in severe traumatic brain injury: results of a phase III randomised, placebo-controlled, clinical trial. Lancet Neurol 5 (2006) 38-45
    • (2006) Lancet Neurol , vol.5 , pp. 38-45
    • Maas, A.I.1    Murray, G.2    Henney III, H.3
  • 58
    • 0033587739 scopus 로고    scopus 로고
    • Differential acute and chronic responses of tumor necrosis factor-deficient mice to experimental brain injury
    • Scherbel U., Raghupathi R., Nakamura M., et al. Differential acute and chronic responses of tumor necrosis factor-deficient mice to experimental brain injury. Proc Natl Acad Sci U S A 96 (1999) 8721-8726
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 8721-8726
    • Scherbel, U.1    Raghupathi, R.2    Nakamura, M.3
  • 59
    • 17544375423 scopus 로고    scopus 로고
    • Experimental closed head injury: analysis of neurological outcome, blood-brain barrier dysfunction, intracranial neutrophil infiltration, and neuronal cell death in mice deficient in genes for pro-inflammatory cytokines
    • Stahel P.F., Shohami E., Younis F.M., et al. Experimental closed head injury: analysis of neurological outcome, blood-brain barrier dysfunction, intracranial neutrophil infiltration, and neuronal cell death in mice deficient in genes for pro-inflammatory cytokines. J Cereb Blood Flow Metab 20 (2000) 369-380
    • (2000) J Cereb Blood Flow Metab , vol.20 , pp. 369-380
    • Stahel, P.F.1    Shohami, E.2    Younis, F.M.3
  • 60
    • 0033178340 scopus 로고    scopus 로고
    • Exacerbation of damage and altered NF-κB activation in mice lacking tumor necrosis factor receptors after traumatic brain injury
    • Sullivan P.G., Bruce-Keller A.J., Rabchevsky A.G., et al. Exacerbation of damage and altered NF-κB activation in mice lacking tumor necrosis factor receptors after traumatic brain injury. J Neurosci 19 (1999) 6248-6256
    • (1999) J Neurosci , vol.19 , pp. 6248-6256
    • Sullivan, P.G.1    Bruce-Keller, A.J.2    Rabchevsky, A.G.3
  • 61
    • 0025916387 scopus 로고
    • The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis
    • Itoh N., et al. The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis. Cell 66 (1991) 233-243
    • (1991) Cell , vol.66 , pp. 233-243
    • Itoh, N.1
  • 62
    • 0028927607 scopus 로고
    • The Fas death factor
    • Nagata S., and Golstein P. The Fas death factor. Science 267 (1995) 1449-1456
    • (1995) Science , vol.267 , pp. 1449-1456
    • Nagata, S.1    Golstein, P.2
  • 63
    • 0027145632 scopus 로고
    • Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family
    • Suda T., Takahashi T., Golstein P., and Nagata S. Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family. Cell 75 (1993) 1169-1178
    • (1993) Cell , vol.75 , pp. 1169-1178
    • Suda, T.1    Takahashi, T.2    Golstein, P.3    Nagata, S.4
  • 64
    • 0344258462 scopus 로고    scopus 로고
    • Fas ligand and Fas are expressed constitutively in human astrocytes and the expression increases with IL-1, IL-6, TNF-α, or IFN-γ
    • Choi C., Park J.Y., Lee J., et al. Fas ligand and Fas are expressed constitutively in human astrocytes and the expression increases with IL-1, IL-6, TNF-α, or IFN-γ. J Immunol 162 (1999) 1889-1895
    • (1999) J Immunol , vol.162 , pp. 1889-1895
    • Choi, C.1    Park, J.Y.2    Lee, J.3
  • 65
    • 0034051781 scopus 로고    scopus 로고
    • Expression of Fas and Fas ligand after experimental traumatic brain injury in the rat
    • Beer R., Franz G., Schöpf M., et al. Expression of Fas and Fas ligand after experimental traumatic brain injury in the rat. J Cereb Blood Flow Metab 20 (2000) 669-677
    • (2000) J Cereb Blood Flow Metab , vol.20 , pp. 669-677
    • Beer, R.1    Franz, G.2    Schöpf, M.3
  • 66
    • 33846277238 scopus 로고    scopus 로고
    • Immunohistochemical characterization of Fas (CD95) and Fas ligand (FasL/CD95L) expression in the injured brain: relationship with neuronal cell death and inflammatory mediators
    • Grosjean M.B., Lenzlinger P.M., Stahel P.F., et al. Immunohistochemical characterization of Fas (CD95) and Fas ligand (FasL/CD95L) expression in the injured brain: relationship with neuronal cell death and inflammatory mediators. Histol Histopathol 22 (2007) 235-250
    • (2007) Histol Histopathol , vol.22 , pp. 235-250
    • Grosjean, M.B.1    Lenzlinger, P.M.2    Stahel, P.F.3
  • 67
    • 0033562658 scopus 로고    scopus 로고
    • CD95 ligand (Fas-L/APO-1L) and tumor necrosis factor-related apoptosis-inducing ligand mediate ischemia-induced apoptosis in neurons
    • Martin-Villalba A., Herr I., Jeremias I., et al. CD95 ligand (Fas-L/APO-1L) and tumor necrosis factor-related apoptosis-inducing ligand mediate ischemia-induced apoptosis in neurons. J Neurosci 19 (1999) 3809-3817
    • (1999) J Neurosci , vol.19 , pp. 3809-3817
    • Martin-Villalba, A.1    Herr, I.2    Jeremias, I.3
  • 68
    • 0036584982 scopus 로고    scopus 로고
    • Upregulation of the Fas receptor death-inducing signaling complex after traumatic brain injury in mice and humans
    • Qiu J., Whalen M.J., Lowenstein P., et al. Upregulation of the Fas receptor death-inducing signaling complex after traumatic brain injury in mice and humans. J Neurosci 22 (2002) 3504-3511
    • (2002) J Neurosci , vol.22 , pp. 3504-3511
    • Qiu, J.1    Whalen, M.J.2    Lowenstein, P.3
  • 69
    • 0034666684 scopus 로고    scopus 로고
    • Fas (CD95/APO-1) plays a role in the pathophysiology of focal cerebral ischemia
    • Rosenbaum D.M., Gupta G., D'Amore J., et al. Fas (CD95/APO-1) plays a role in the pathophysiology of focal cerebral ischemia. J Neurosci Res 61 (2000) 686-692
    • (2000) J Neurosci Res , vol.61 , pp. 686-692
    • Rosenbaum, D.M.1    Gupta, G.2    D'Amore, J.3
  • 70
    • 0028919473 scopus 로고
    • Expression of the functional soluble form of human fas ligand in activated lymphocytes
    • Tanaka M., Suda T., Takahashi T., and Nagata S. Expression of the functional soluble form of human fas ligand in activated lymphocytes. EMBO J 14 (1995) 1129-1135
    • (1995) EMBO J , vol.14 , pp. 1129-1135
    • Tanaka, M.1    Suda, T.2    Takahashi, T.3    Nagata, S.4
  • 71
    • 0031457493 scopus 로고    scopus 로고
    • Detectable concentrations of Fas ligand in cerebrospinal fluid after severe head injury
    • Ertel W., Keel M., Stocker R., et al. Detectable concentrations of Fas ligand in cerebrospinal fluid after severe head injury. J Neuroimmunol 80 (1997) 93-96
    • (1997) J Neuroimmunol , vol.80 , pp. 93-96
    • Ertel, W.1    Keel, M.2    Stocker, R.3
  • 72
    • 0036145564 scopus 로고    scopus 로고
    • Prolonged intrathecal release of soluble Fas following severe traumatic brain injury in humans
    • Lenzlinger P.M., Marx A., Trentz O., Kossmann T., and Morganti-Kossmann M.C. Prolonged intrathecal release of soluble Fas following severe traumatic brain injury in humans. J Neuroimmunol 122 (2002) 167-174
    • (2002) J Neuroimmunol , vol.122 , pp. 167-174
    • Lenzlinger, P.M.1    Marx, A.2    Trentz, O.3    Kossmann, T.4    Morganti-Kossmann, M.C.5
  • 73
    • 0038618996 scopus 로고    scopus 로고
    • Fas (CD95) induces proinflammatory cytokine responses by human monocytes and monocyte-derived macrophages
    • Park D.R., Thomsen A.R., Frevert C.W., et al. Fas (CD95) induces proinflammatory cytokine responses by human monocytes and monocyte-derived macrophages. J Immunol 170 (2003) 6209-6216
    • (2003) J Immunol , vol.170 , pp. 6209-6216
    • Park, D.R.1    Thomsen, A.R.2    Frevert, C.W.3
  • 74
    • 0024421453 scopus 로고
    • Neutrophil-activating peptide-1/interleukin 8, a novel cytokine that activates neutrophils
    • Baggiolini M., Walz A., and Kunkel S.L. Neutrophil-activating peptide-1/interleukin 8, a novel cytokine that activates neutrophils. J Clin Invest 84 (1989) 1045-1049
    • (1989) J Clin Invest , vol.84 , pp. 1045-1049
    • Baggiolini, M.1    Walz, A.2    Kunkel, S.L.3
  • 75
    • 0026012126 scopus 로고
    • Interleukin-8 induces neutrophil transendothelial migration
    • Smith W.B., Gamble J.R., Clark-Lewis I., and Vadas M.A. Interleukin-8 induces neutrophil transendothelial migration. Immunology 72 (1991) 65-72
    • (1991) Immunology , vol.72 , pp. 65-72
    • Smith, W.B.1    Gamble, J.R.2    Clark-Lewis, I.3    Vadas, M.A.4
  • 76
    • 0037413502 scopus 로고    scopus 로고
    • CXC-chemokines KC and macrophage inflammatory protein-2 (MIP-2) synergistically induce leukocyte recruitment to the central nervous system in rats
    • Zwijnenburg P.J., Polfliet M.M., Florquin S., et al. CXC-chemokines KC and macrophage inflammatory protein-2 (MIP-2) synergistically induce leukocyte recruitment to the central nervous system in rats. Immunol Lett 85 (2003) 1-4
    • (2003) Immunol Lett , vol.85 , pp. 1-4
    • Zwijnenburg, P.J.1    Polfliet, M.M.2    Florquin, S.3
  • 77
    • 0026760984 scopus 로고
    • Production of hemolymphopoietic cytokines (IL-6, IL-8, colony-stimulating factors) by normal human astrocytes in response to IL-1β and tumor necrosis factor-α
    • Aloisi F., Carè A., Borsellino G., et al. Production of hemolymphopoietic cytokines (IL-6, IL-8, colony-stimulating factors) by normal human astrocytes in response to IL-1β and tumor necrosis factor-α. J Immunol 149 (1992) 2358-2366
    • (1992) J Immunol , vol.149 , pp. 2358-2366
    • Aloisi, F.1    Carè, A.2    Borsellino, G.3
  • 78
    • 0034057762 scopus 로고    scopus 로고
    • Interleukin-8 is increased in cerebrospinal fluid of children with severe head injury
    • Whalen M.J., Carlos T.M., Kochanek P.M., et al. Interleukin-8 is increased in cerebrospinal fluid of children with severe head injury. Crit Care Med 28 (2000) 929-934
    • (2000) Crit Care Med , vol.28 , pp. 929-934
    • Whalen, M.J.1    Carlos, T.M.2    Kochanek, P.M.3
  • 79
    • 0030903563 scopus 로고    scopus 로고
    • Production of cytokines following brain injury: beneficial and deleterious for the damaged tissue
    • Morganti-Kossmann M.C., Lenzlinger P.M., Hans V., et al. Production of cytokines following brain injury: beneficial and deleterious for the damaged tissue. Mol Psychiatry 2 (1997) 133-136
    • (1997) Mol Psychiatry , vol.2 , pp. 133-136
    • Morganti-Kossmann, M.C.1    Lenzlinger, P.M.2    Hans, V.3
  • 80
    • 0024590507 scopus 로고
    • Purification and amino acid analysis of two human monocyte chemoattractants produced by phytohemagglutinin-stimulated human blood mononuclear leukocytes
    • Yoshimura T., Robinson E.A., Tanaka S., Appella E., and Leonard E.J. Purification and amino acid analysis of two human monocyte chemoattractants produced by phytohemagglutinin-stimulated human blood mononuclear leukocytes. J Immunol 142 (1989) 1956-1962
    • (1989) J Immunol , vol.142 , pp. 1956-1962
    • Yoshimura, T.1    Robinson, E.A.2    Tanaka, S.3    Appella, E.4    Leonard, E.J.5
  • 81
    • 0029931236 scopus 로고    scopus 로고
    • Chemokine monocyte chemoattractant protein-1 is expressed by astrocytes after mechanical injury to the brain
    • Glabinski A.R., Balasingam V., Tani M., et al. Chemokine monocyte chemoattractant protein-1 is expressed by astrocytes after mechanical injury to the brain. J Immunol 156 (1996) 4363-4368
    • (1996) J Immunol , vol.156 , pp. 4363-4368
    • Glabinski, A.R.1    Balasingam, V.2    Tani, M.3
  • 82
    • 0036319505 scopus 로고    scopus 로고
    • Distribution, cellular localization and functional role of CCR2 chemokine receptors in adult rat brain
    • Banisadr G., et al. Distribution, cellular localization and functional role of CCR2 chemokine receptors in adult rat brain. J Neurochem 81 (2002) 257-269
    • (2002) J Neurochem , vol.81 , pp. 257-269
    • Banisadr, G.1
  • 83
    • 33745890639 scopus 로고    scopus 로고
    • Brain cytokine synthesis induced by an intraparenchymal injection of LPS is reduced in MCP-1-deficient mice prior to leucocyte recruitment
    • Rankine E.L., Hughes P.M., Botham M.S., Perry V.H., and Felton L.M. Brain cytokine synthesis induced by an intraparenchymal injection of LPS is reduced in MCP-1-deficient mice prior to leucocyte recruitment. Eur J Neurosci 24 (2006) 77-86
    • (2006) Eur J Neurosci , vol.24 , pp. 77-86
    • Rankine, E.L.1    Hughes, P.M.2    Botham, M.S.3    Perry, V.H.4    Felton, L.M.5
  • 84
    • 0030892402 scopus 로고    scopus 로고
    • Differential and time-dependent expression of monocyte chemoattractant protein-1 mRNA by astrocytes and macrophages in rat brain: effects of ischemia and peripheral lipopolysaccharide administration
    • Gourmala N.G., Buttini M., Limonta S., Sauter A., and Boddeke H.W. Differential and time-dependent expression of monocyte chemoattractant protein-1 mRNA by astrocytes and macrophages in rat brain: effects of ischemia and peripheral lipopolysaccharide administration. J Neuroimmunol 74 (1997) 35-44
    • (1997) J Neuroimmunol , vol.74 , pp. 35-44
    • Gourmala, N.G.1    Buttini, M.2    Limonta, S.3    Sauter, A.4    Boddeke, H.W.5
  • 85
    • 0033797853 scopus 로고    scopus 로고
    • Acute excitotoxic injury induces expression of monocyte chemoattractant protein-1 and its receptor, CCR2, in neonatal rat brain
    • Galasso J.M., Miller M.J., Cowell R.M., Harrison J.K., Warren J.S., and Silverstein F.S. Acute excitotoxic injury induces expression of monocyte chemoattractant protein-1 and its receptor, CCR2, in neonatal rat brain. Exp Neurol 165 (2000) 295-305
    • (2000) Exp Neurol , vol.165 , pp. 295-305
    • Galasso, J.M.1    Miller, M.J.2    Cowell, R.M.3    Harrison, J.K.4    Warren, J.S.5    Silverstein, F.S.6
  • 87
    • 0032536531 scopus 로고    scopus 로고
    • Abnormalities in monocyte recruitment and cytokine expression in monocyte chemoattractant protein 1-deficient mice
    • Lu B., Rutledge B.J., Gu L., et al. Abnormalities in monocyte recruitment and cytokine expression in monocyte chemoattractant protein 1-deficient mice. J Exp Med 187 (1998) 601-608
    • (1998) J Exp Med , vol.187 , pp. 601-608
    • Lu, B.1    Rutledge, B.J.2    Gu, L.3
  • 88
    • 20444399890 scopus 로고    scopus 로고
    • Final results of MRC CRASH, a randomised placebo-controlled trial of intravenous corticosteroid in adults with head injury: outcomes at 6 months
    • CRASH trial collaborators
    • Edwards P., Arango M., Balica L., et al., CRASH trial collaborators. Final results of MRC CRASH, a randomised placebo-controlled trial of intravenous corticosteroid in adults with head injury: outcomes at 6 months. Lancet 365 (2005) 1957-1959
    • (2005) Lancet , vol.365 , pp. 1957-1959
    • Edwards, P.1    Arango, M.2    Balica, L.3
  • 89
    • 0029160270 scopus 로고
    • Delayed onset of Alzheimer's disease with nonsteroidal anti-inflammatory and histamine H2 blocking drugs
    • Breitner J.C., Welsh K.A., and Helms M.J. Delayed onset of Alzheimer's disease with nonsteroidal anti-inflammatory and histamine H2 blocking drugs. Neurobiol Aging 16 (1995) 523-530
    • (1995) Neurobiol Aging , vol.16 , pp. 523-530
    • Breitner, J.C.1    Welsh, K.A.2    Helms, M.J.3
  • 90
    • 0038375640 scopus 로고    scopus 로고
    • Effect of non-steroidal anti-inflammatory drugs on risk of Alzheimer's disease: systematic review and meta-analysis of observational studies
    • Etminan M., Gill S., and Samii A. Effect of non-steroidal anti-inflammatory drugs on risk of Alzheimer's disease: systematic review and meta-analysis of observational studies. BMJ 327 (2003) 128
    • (2003) BMJ , vol.327 , pp. 128
    • Etminan, M.1    Gill, S.2    Samii, A.3
  • 91
    • 26444475416 scopus 로고    scopus 로고
    • Novel therapeutic opportunities for Alzheimer's disease: focus on nonsteroidal anti-inflammatory drugs
    • Townsend K.P., and Praticò D. Novel therapeutic opportunities for Alzheimer's disease: focus on nonsteroidal anti-inflammatory drugs. FASEB J 19 (2005) 1592-1601
    • (2005) FASEB J , vol.19 , pp. 1592-1601
    • Townsend, K.P.1    Praticò, D.2
  • 92
    • 33748439924 scopus 로고    scopus 로고
    • Chronic ibuprofen administration worsens cognitive outcome following traumatic brain injury in rats
    • Browne K.D., Iwata A., Putt M.E., and Smith D.H. Chronic ibuprofen administration worsens cognitive outcome following traumatic brain injury in rats. Exp Neurol 201 (2006) 301-307
    • (2006) Exp Neurol , vol.201 , pp. 301-307
    • Browne, K.D.1    Iwata, A.2    Putt, M.E.3    Smith, D.H.4
  • 93
    • 33745457705 scopus 로고    scopus 로고
    • Minocycline inhibits poly(ADP-ribose) polymerase-1 at nanomolar concentrations
    • Alano C.C., Kauppinen T.M., Valls A.V., and Swanson R.A. Minocycline inhibits poly(ADP-ribose) polymerase-1 at nanomolar concentrations. Proc Natl Acad Sci U S A 103 (2006) 9685-9690
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 9685-9690
    • Alano, C.C.1    Kauppinen, T.M.2    Valls, A.V.3    Swanson, R.A.4
  • 94
    • 22244441777 scopus 로고    scopus 로고
    • Physiological levels of pro- and anti-inflammatory mediators in cerebrospinal fluid and plasma: a normative study
    • Maier B., Laurer H.L., Rose S., Buurman W.A., and Marzi I. Physiological levels of pro- and anti-inflammatory mediators in cerebrospinal fluid and plasma: a normative study. J Neurotrauma 22 (2005) 822-835
    • (2005) J Neurotrauma , vol.22 , pp. 822-835
    • Maier, B.1    Laurer, H.L.2    Rose, S.3    Buurman, W.A.4    Marzi, I.5
  • 95
    • 1542376941 scopus 로고    scopus 로고
    • Minocycline treatment reduces delayed oligodendrocyte death, attenuates axonal dieback, and improves functional outcome after spinal cord injury
    • Stirling D.P., Khodarahmi K., Liu J., et al. Minocycline treatment reduces delayed oligodendrocyte death, attenuates axonal dieback, and improves functional outcome after spinal cord injury. J Neurosci 24 (2004) 2182-2190
    • (2004) J Neurosci , vol.24 , pp. 2182-2190
    • Stirling, D.P.1    Khodarahmi, K.2    Liu, J.3
  • 96
    • 2642545055 scopus 로고    scopus 로고
    • Low dose intravenous minocycline is neuroprotective after middle cerebral artery occlusion-reperfusion in rats
    • Xu L., Fagan S.C., Waller J.L., et al. Low dose intravenous minocycline is neuroprotective after middle cerebral artery occlusion-reperfusion in rats. BMC Neurol 4 (2004) 7
    • (2004) BMC Neurol , vol.4 , pp. 7
    • Xu, L.1    Fagan, S.C.2    Waller, J.L.3
  • 97
    • 0031595870 scopus 로고    scopus 로고
    • Interleukin-1β and the interleukin-1 receptor antagonist act in the striatum to modify excitotoxic brain damage in the rat
    • Lawrence C.B., Allan S.M., and Rothwell N.J. Interleukin-1β and the interleukin-1 receptor antagonist act in the striatum to modify excitotoxic brain damage in the rat. Eur J Neurosci 10 (1998) 1188-1195
    • (1998) Eur J Neurosci , vol.10 , pp. 1188-1195
    • Lawrence, C.B.1    Allan, S.M.2    Rothwell, N.J.3
  • 98
    • 0028829231 scopus 로고
    • IL-6 expression in neurons of transgenic mice causes reactive astrocytosis and increase in ramified microglial cells but no neuronal damage
    • Fattori E., Lazzaro D., Musiani P., Modesti A., Alonzi T., and Ciliberto G. IL-6 expression in neurons of transgenic mice causes reactive astrocytosis and increase in ramified microglial cells but no neuronal damage. Eur J Neurosci 7 (1995) 2441-2449
    • (1995) Eur J Neurosci , vol.7 , pp. 2441-2449
    • Fattori, E.1    Lazzaro, D.2    Musiani, P.3    Modesti, A.4    Alonzi, T.5    Ciliberto, G.6
  • 99
    • 23644445498 scopus 로고    scopus 로고
    • The hematopoietic factor G-CSF is a neuronal ligand that counteracts programmed cell death and drives neurogenesis
    • Schneider A., Krüger C., Steigleder T., et al. The hematopoietic factor G-CSF is a neuronal ligand that counteracts programmed cell death and drives neurogenesis. J Clin Invest 115 (2005) 2083-2098
    • (2005) J Clin Invest , vol.115 , pp. 2083-2098
    • Schneider, A.1    Krüger, C.2    Steigleder, T.3
  • 100
    • 34248225837 scopus 로고    scopus 로고
    • Potentiation of neurogenesis and angiogenesis by G-CSF after focal cerebral ischemia in rats
    • Sehara Y., Hayashi T., Deguchi K., et al. Potentiation of neurogenesis and angiogenesis by G-CSF after focal cerebral ischemia in rats. Brain Res 1151 (2007) 142-149
    • (2007) Brain Res , vol.1151 , pp. 142-149
    • Sehara, Y.1    Hayashi, T.2    Deguchi, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.