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Volumn 16, Issue 6, 2011, Pages 2372-2388

Protective role of heme oxygenase-1 against inflammation in atherosclerosis

Author keywords

Adaptive immunity; Atherosclerosis; Bilirubin; Biliverdin; Carbon monoxide; Heme; Heme oxygenase 1; Immune cells; Inflammation; Innate immunity; Review

Indexed keywords

AUTACOID; CYTOKINE; HEME; HEME OXYGENASE 1;

EID: 79959702836     PISSN: 27686701     EISSN: 27686698     Source Type: Journal    
DOI: 10.2741/3860     Document Type: Review
Times cited : (72)

References (158)
  • 4
    • 70450189795 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis: From pathophysiology to practice
    • for the Leducq Transatlantic Network on Atherothrombosis
    • Libby. P., P.M. Ridker and G.K. Hansson for the Leducq Transatlantic Network on Atherothrombosis: Inflammation in atherosclerosis: from pathophysiology to practice. J Am Coll Cardiol 54, 2129-2138 (2009)
    • (2009) J Am Coll Cardiol , vol.54 , pp. 2129-2138
    • Libby, P.1    Ridker, P.M.2    Hansson, G.K.3
  • 5
    • 33745571976 scopus 로고    scopus 로고
    • The immune response in atherosclerosis: A double-edged sword
    • DOI 10.1038/nri1882, PII N1882
    • Hansson, G.K. and P. Libby: The immune response in atherosclerosis: a double-edged sword. Nat Rev Immunol 6, 508-519 (2006) (Pubitemid 43980523)
    • (2006) Nature Reviews Immunology , vol.6 , Issue.7 , pp. 508-519
    • Hansson, G.K.1    Libby, P.2
  • 6
    • 69249205739 scopus 로고    scopus 로고
    • Obesity, inflammation, and atherosclerosis
    • Rocha, V.Z. and P. Libby: Obesity, inflammation, and atherosclerosis. Nat Rev Cardiol 6, 399-409 (2009)
    • (2009) Nat Rev Cardiol , vol.6 , pp. 399-409
    • Rocha, V.Z.1    Libby, P.2
  • 7
    • 0014348401 scopus 로고
    • The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase
    • Tenhunen, R., H.S. Marver and R. Schmid: The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase. Proc Natl Acad Sci USA 61, 748-755 (1968)
    • (1968) Proc Natl Acad Sci USA , vol.61 , pp. 748-755
    • Tenhunen, R.1    Marver, H.S.2    Schmid, R.3
  • 8
    • 0023731036 scopus 로고
    • Heme oxygenase: Functions, multiplicity, regulatory mechanisms, and clinical applications
    • Maines, M.D: Heme oxygenase: functions, multiplicity, regulatory mechanisms, and clinical applications. FASEB J 2, 2557-2568 (1989)
    • (1989) FASEB J , vol.2 , pp. 2557-2568
    • Maines, M.D.1
  • 10
    • 41149177025 scopus 로고    scopus 로고
    • Pharmacological and clinical aspects of heme oxygenase
    • DOI 10.1124/pr.107.07104
    • Abraham, N.G. and A. Kappas: Pharmacological and clinical aspects of heme oxygenase. Pharmacol Rev 60, 79-127 (2008) (Pubitemid 351439218)
    • (2008) Pharmacological Reviews , vol.60 , Issue.1 , pp. 79-127
    • Abraham, N.G.1    Kappas, A.2
  • 11
    • 33645945014 scopus 로고    scopus 로고
    • Heme oxygenase-1/carbon monoxide: From basic science to therapeutic applications
    • Ryter, S.W., J. Alam and A.M.K. Choi: Heme oxygenase-1/carbon monoxide: from basic science to therapeutic applications. Physiol Rev 86, 583-650 (2006)
    • (2006) Physiol Rev , vol.86 , pp. 583-650
    • Ryter, S.W.1    Alam, J.2    Choi, A.M.K.3
  • 13
    • 0030045835 scopus 로고    scopus 로고
    • Heme oxygenase: A novel target for the modulation of the inflammatory response
    • DOI 10.1038/nm0196-87
    • Willis, D., A.R. Moore, R. Frederick and D.A. Willoughby: Heme oxygenase: a novel target for the modulation of the inflammatory response. Nat Med 2, 87-90 (1996) (Pubitemid 26029572)
    • (1996) Nature Medicine , vol.2 , Issue.1 , pp. 87-90
    • Willis, D.1    Moore, A.R.2    Frederick, R.3    Willoughby, D.A.4
  • 14
    • 33750936809 scopus 로고    scopus 로고
    • Protective effects of heme-oxygenase expression against endotoxic shock: Inhibition of tumor necrosis factor-α and augmentation of interleukin-10
    • DOI 10.1097/01.ta.0000239359.41464.ef, PII 0000537320061100000009
    • Tamion, F., V. Richard, S. Renet and C. Thuillez. Protective effects of heme oxygenase-1 expression against endotoxin shock: inhibition of tumor necrosis factor-alpha and augmentation of interleukin-10. J Trauma 61, 1078-1084 (2006) (Pubitemid 44737010)
    • (2006) Journal of Trauma - Injury, Infection and Critical Care , vol.61 , Issue.5 , pp. 1078-1084
    • Tamion, F.1    Richard, V.2    Renet, S.3    Thuillez, C.4
  • 16
    • 0034055982 scopus 로고    scopus 로고
    • Renal response to tissue injury: Lessons from heme oxygenase-1 gene ablation and expression
    • Agarwal, A and H.S. Nick: Renal response to tissue injury: lessons from heme oxygenase-1 gene ablation and expression. J Am Soc Nephrol 11, 965-973 (2001) (Pubitemid 30241733)
    • (2000) Journal of the American Society of Nephrology , vol.11 , Issue.5 , pp. 965-973
    • Agarwal, A.1    Nick, H.S.2
  • 18
    • 0032900940 scopus 로고    scopus 로고
    • Exogenous administration of heme oxygenase-1 by gene transfer provides protection against hyperoxia-induced lung injury
    • Otterbein, L.E., J.K. Kolls, L.L. Mantell, J.L. Cook, J. Alam and A.M. Choi: Exogenous administration of heme oxygenase-1 by gene transfer provides protection against hyperoxia-induced lung injury. J Clin Invest 103, 1047-1054 (1999) (Pubitemid 29169613)
    • (1999) Journal of Clinical Investigation , vol.103 , Issue.7 , pp. 1047-1054
    • Otterbein, L.E.1    Kolls, J.K.2    Mantell, L.L.3    Cook, J.L.4    Alam, J.5    Choi, A.M.K.6
  • 21
    • 34547686232 scopus 로고    scopus 로고
    • Heme oxygenase-1 in organ transplantation
    • Soares, M.P. and F.H. Bach: Heme oxygenase-1 in organ transplantation. Front Biosci 12, 4932-4945 (2007)
    • (2007) Front Biosci , vol.12 , pp. 4932-4945
    • Soares, M.P.1    Bach, F.H.2
  • 22
    • 33845299566 scopus 로고    scopus 로고
    • Protective effect of carbon monoxide in transplantation
    • DOI 10.1111/j.1582-4934.2006.tb00426.x
    • Nakao, A., A.M.K. Choi and N. Murase: Protective effect of carbon monoxide in transplantation. J Cell Mol Med 10, 650-671 (2006) (Pubitemid 44874275)
    • (2006) Journal of Cellular and Molecular Medicine , vol.10 , Issue.3 , pp. 650-671
    • Nakao, A.1    Choi, A.M.K.2    Murase, N.3
  • 23
    • 0031757984 scopus 로고    scopus 로고
    • Antibody-induced transplant arteriosclerosis is prevented by graft expression of anti-oxidant and anti-apoptotic genes
    • DOI 10.1038/3982
    • Hancock, W.W., R. Buelow, M.H. Sayegh and L.A. Turka: Antibody-induced transplant arteriosclerosis is prevented by graft expression of anti-oxidant and antiapoptotic genes. Nat Med 4, 1392-1396 (1998) (Pubitemid 28553461)
    • (1998) Nature Medicine , vol.4 , Issue.12 , pp. 1392-1396
    • Hancock, W.W.1    Buelow, R.2    Sayegh, M.H.3    Turka, L.A.4
  • 28
    • 0036151729 scopus 로고    scopus 로고
    • Heme oxygenase-1 deficiency: The first autopsy case
    • DOI 10.1053/hupa.2002.30217
    • Kawashima, A., T. Oda, A. Yachie, S. Koizumi and I. Nakanishi: Heme oxygenase-1 deficiency: the first autopsy case. Hum Pathol 33, 125-130 (2002) (Pubitemid 34112962)
    • (2002) Human Pathology , vol.33 , Issue.1 , pp. 125-130
    • Kawashima, A.1    Oda, Y.2    Yachie, A.3    Koizumi, S.4    Nakanishi, I.5
  • 29
    • 0030951001 scopus 로고    scopus 로고
    • Serum bilirubin distribution and its relation to cardiovascular risk in children and young adults
    • DOI 10.1016/S0021-9150(97)06088-7, PII S0021915097060887
    • Madhavan, M., W.A. Wattigney, S.R. Srinivasan and G.S. Berenson: Serum bilirubin distribution and its relation to cardiovascular risk in children and young adults. Atherosclerosis 131, 107-113 (1997) (Pubitemid 27240103)
    • (1997) Atherosclerosis , vol.131 , Issue.1 , pp. 107-113
    • Madhavan, M.1    Wattigney, W.A.2    Srinivasan, S.R.3    Berenson, G.S.4
  • 30
    • 33847017691 scopus 로고    scopus 로고
    • Low serum bilirubin concentrations are associated with impaired aortic elastic properties, but not impaired left ventricular diastolic function
    • Caliskan, M., D. Erdogan, H. Gullu, D. Tok, M. Bilgi and H. Muderrisoglu: Low serum bilirubin concentrations are associated with impaired aortic elastic properties, but not impaired left ventricular diastolic function. Int J Clin Pract 61, 218-224 (2007)
    • (2007) Int J Clin Pract , vol.61 , pp. 218-224
    • Caliskan, M.1    Erdogan, D.2    Gullu, H.3    Tok, D.4    Bilgi, M.5    Muderrisoglu, H.6
  • 31
    • 0036624989 scopus 로고    scopus 로고
    • Neutrophil activation by heme: Implications for inflammatory processes
    • DOI 10.1182/blood.V99.11.4160
    • Graca-Souza, A.V., M.A. Arruda, M.S. de Freitas, C. Barja-Fidalgo and P.L. Oliveira: Neutrophil activation by heme: implications for inflammatory processes. Blood 99, 4160-4165 (2002) (Pubitemid 35332061)
    • (2002) Blood , vol.99 , Issue.11 , pp. 4160-4165
    • Graca-Souza, A.V.1    Arruda, M.A.B.2    De Freitas, M.S.3    Barja-Fidalgo, C.4    Oliveira, P.L.5
  • 35
    • 0141988655 scopus 로고    scopus 로고
    • Anti-inflammatory actions of the heme oxygenase-1 pathway
    • DOI 10.2174/1381612033453749
    • Alcaraz, M.J., P. Fernandez and M.I. Guillen: Antiinflammatory actions of the heme oxygenase pathway. Curr Drug Des 9, 2541-2551 (2003) (Pubitemid 37236372)
    • (2003) Current Pharmaceutical Design , vol.9 , Issue.30 , pp. 2541-2551
    • Alcaraz, M.J.1    Fernandez, P.2    Guillen, M.I.3
  • 36
    • 61449417240 scopus 로고    scopus 로고
    • Heme oxygenase-1 and carbon monoxide: Emerging therapeutic targets in inflammation and allergy
    • Pae, H.-O., Y.C. Lee and H.-T. Chung: Heme oxygenase-1 and carbon monoxide: emerging therapeutic targets in inflammation and allergy. Recent Patents Inflammation Allergy Drug Discovery 2, 159-165 (2008)
    • (2008) Recent Patents Inflammation Allergy Drug Discovery , vol.2 , pp. 159-165
    • Pae, H.-O.1    Lee, Y.C.2    Chung, H.-T.3
  • 38
    • 0031935208 scopus 로고    scopus 로고
    • Expression of heme oxygenase-1 in atherosclerotic lesions
    • Wang, L.J., T.S. Lee, F.Y. Lee, R.C. Pai and L.Y. Chau: Expression of heme oxygenase-1 in atherosclerotic lesions. Am J Pathol 152, 711-720 (1998)
    • (1998) Am J Pathol , vol.152 , pp. 711-720
    • Wang, L.J.1    Lee, T.S.2    Lee, F.Y.3    Pai, R.C.4    Chau, L.Y.5
  • 41
    • 33745763562 scopus 로고    scopus 로고
    • Haem oxygenase-1 expression and coronary heart disease-association between levels of haem oxygenase-1 expression and angiographic morphology as well as the quantity of coronary lesions
    • Li, Y.G., D.M. Wang, S.M. Chen, X.R. Tan, X.Y. Fang, J.W. Wu, G.H Zhang and R.Q. Mai: Haem oxygenase-1 expression and coronary heart disease-association between levels of haem oxygenase-1 expression and angiographic morphology as well as the quantity of coronary lesions. Acta Cardiol 61, 295-300 (2006)
    • (2006) Acta Cardiol , vol.61 , pp. 295-300
    • Li, Y.G.1    Wang, D.M.2    Chen, S.M.3    Tan, X.R.4    Fang, X.Y.5    Wu, J.W.6    Zhang, G.H.7    Mai, R.Q.8
  • 42
    • 24644439178 scopus 로고    scopus 로고
    • Heme oxygenase-1 is expressed in carotid atherosclerotic plaque infected by Helicobacter pylori and is more prevalent in asymptomatic patients
    • Ameriso, S.F., A.R. Villamil, C. Zedda, J.C. Parodi, S. Garrido, M.I. Sarchi, M. Shultz, J. Bocskowski and G.E Sevlever: Heme oxygenase-1 is expressed in carotid atherosclerotic plaque infected by Helicobacter pylori and is more prevalent in asymptomatic patients. Stroke 36, 1896-1890 (2005)
    • (2005) Stroke , vol.36 , pp. 1896-1890
    • Ameriso, S.F.1    Villamil, A.R.2    Zedda, C.3    Parodi, J.C.4    Garrido, S.5    Sarchi, M.I.6    Shultz, M.7    Bocskowski, J.8    Sevlever, G.E.9
  • 44
    • 0036792526 scopus 로고    scopus 로고
    • Heme oxygenase-1 gene promoter polymorphism is associated with coronary artery disease in Japanese patients with coronary risk factors
    • Kaneda, H., M. Ohno, J. Taguchi, H. Hashimoto, T. Ogasawura, T. Aizawa, N. Ishizaka and R. Nagai: Heme oxygenase-1 gene promoter polymorphism is associated with coronary artery disease in Japanese patients with coronary risk factors. Arterioscler Thromb Vasc Biol 22, 1680-1685 (2002)
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 1680-1685
    • Kaneda, H.1    Ohno, M.2    Taguchi, J.3    Hashimoto, H.4    Ogasawura, T.5    Aizawa, T.6    Ishizaka, N.7    Nagai, R.8
  • 46
  • 48
    • 0141706806 scopus 로고    scopus 로고
    • Absence of heme oxygenase-1 exacerbates atherosclerosis lesion formation and vascular remodeling
    • Yet, S.F., M.D. Layne, X. Liu, Y.H. Chen, B. Ith, N.E. Sibing and M.A. Perrella: Absence of heme oxygenase-1 exacerbates atherosclerosis lesion formation and vascular remodeling. FASEB J 17, 1759-1761 (2003)
    • (2003) FASEB J , vol.17 , pp. 1759-1761
    • Yet, S.F.1    Layne, M.D.2    Liu, X.3    Chen, Y.H.4    Ith, B.5    Sibing, N.E.6    Perrella, M.A.7
  • 49
    • 0035949615 scopus 로고    scopus 로고
    • Adenovirus-mediated heme oxygenase-1 gene transfer inhibits the development of atherosclerosis in apolipoprotein e-deficient mice
    • Juan, S.H., T.S. Lee, K.W. Tseng, J.Y. Liou, S.K. Shyue, K.K.Wu and L.Y. Chau: Adenovirus-mediated heme oxygenase-1 gene transfer inhibits the development of atherosclerosis in apolipoprotein Edeficient mice. Circulation 104, 1519-1525 (2001) (Pubitemid 32917345)
    • (2001) Circulation , vol.104 , Issue.13 , pp. 1519-1525
    • Juan, S.-H.1    Lee, T.-S.2    Tseng, K.-W.3    Liou, J.-Y.4    Shyue, S.-K.5    Wu, K.K.6    Chau, L.-Y.7
  • 51
    • 37049001399 scopus 로고    scopus 로고
    • Adenovirus-Mediated Heme Oxygenase Transfer Inhibits Graft Arteriosclerosis in Rat Aortic Transplants
    • DOI 10.1016/j.transproceed.2007.03.114, PII S0041134507011232
    • Du, D., S. Chang, B. Chen, H. Zhou and Z.K. Chen: Adenovirus-mediated heme oxygenase transfer inhibits graft arteriosclerosis in rat aortic transplants. Transpl Proc 39, 3446-3448 (2007) (Pubitemid 350251447)
    • (2007) Transplantation Proceedings , vol.39 , Issue.10 , pp. 3446-3448
    • Du, D.1    Chang, S.2    Chen, B.3    Zhou, H.4    Chen, Z.K.5
  • 52
    • 0037674918 scopus 로고    scopus 로고
    • Prevention of chronic deterioration of heart allograft by recombinant adeno-associated virus-mediated heme oxygenase-1 gene transfer
    • Tsui, T.Y., X. Wu, C.K. Lau, D.W. Ho, T. Xu, Y.T. Siu and S.T. Fan: Prevention of chronic deterioration of heart allograft by recombinant adeno-associated virus-mediated heme oxygenase-1 gene transfer. Circulation 107, 2623-2629 (2003) (Pubitemid 36628946)
    • (2003) Circulation , vol.107 , Issue.20 , pp. 2623-2629
    • Tsui, T.-Y.1    Wu, X.2    Lau, C.-K.3    Ho, D.W.Y.4    Xu, T.5    Siu, Y.-T.6    Fan, S.-T.7
  • 53
    • 0023132858 scopus 로고
    • Bilirubin is an antioxidant of possible physiological importance
    • Stocker, R., Y. Yamamoto, A.F. McDonagh, A.N. Glazer and B.N. Ames: Bilirubin is an antioxidant of possible physiological importance. Science 235, 1043-1046 (1987) (Pubitemid 17049750)
    • (1987) Science , vol.235 , Issue.4792 , pp. 1043-1046
    • Stocker, R.1    Yamamoto, Y.2    McDonagh, A.F.3
  • 54
    • 0028239795 scopus 로고
    • Free and albumin-bound bilirubin are efficient co-antioxidants for α-tocopherol, inhibiting plasma and low density lipoprotein peroxidation
    • Neuzil, J and R. Stocker: Free and albumin-bound bilirubin are efficient co-antioxidants for α-tocopherol, inhibiting plasma and low density lipoprotein peroxidation. J Biol Chem 269, 16712-16719 (1994)
    • (1994) J Biol Chem , vol.269 , pp. 16712-16719
    • Neuzil, J.1    Stocker, R.2
  • 56
    • 33646019300 scopus 로고    scopus 로고
    • Carbon monoxide, oxidative stress, and mitochondrial permeability pore transition
    • Piantadosi,C.A., M.S. Carraway and H.B. Suliman: Carbon monoxide, oxidative stress, and mitochondrial permeability pore transition. Free Radic Biol Med 40, 1332-1339 (2006)
    • (2006) Free Radic Biol Med , vol.40 , pp. 1332-1339
    • Piantadosi, C.A.1    Carraway, M.S.2    Suliman, H.B.3
  • 57
    • 21844468521 scopus 로고    scopus 로고
    • Mitochondrial respiratory chain and NAD(P)H oxidase are targets for the antiproliferative effect of carbon monoxide in human airway smooth muscle
    • DOI 10.1074/jbc.M503512200
    • Taille, C., J. El-Benna, S. Lanone, J. Boczkowski and R. Motterlini: Mitochondrial respiratory chain and NAD(P)H oxidase are targets for the antiproliferative effect of carbon monoxide in human airway smooth muscle. J Biol Chem 280, 25350-25360 (2005) (Pubitemid 40962237)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.27 , pp. 25350-25360
    • Taille, C.1    El-Benna, J.2    Lanone, S.3    Boczkowski, J.4    Motterlini, R.5
  • 60
    • 33745513491 scopus 로고    scopus 로고
    • 3-Hydorxyanthranilic acid, one of Ltryptophan metabolites, inhibits monocyte chemoattractant protein-1 secretion and vascular cell adhesion molecule-1 expression via heme oxygenase-1 induction in human umbilical vein endothelial cells
    • Pae, H.O., G.S. Oh, B.S. Lee, J.S. Rim, Y.M. Kim and H.T. Chung: 3-Hydorxyanthranilic acid, one of Ltryptophan metabolites, inhibits monocyte chemoattractant protein-1 secretion and vascular cell adhesion molecule-1 expression via heme oxygenase-1 induction in human umbilical vein endothelial cells. Atherosclerosis 187, 274-284 (2006)
    • (2006) Atherosclerosis , vol.187 , pp. 274-284
    • Pae, H.O.1    Oh, G.S.2    Lee, B.S.3    Rim, J.S.4    Kim, Y.M.5    Chung, H.T.6
  • 62
    • 77951160872 scopus 로고    scopus 로고
    • Bilirubin effect on endothelial adhesion molecules expression is mediated by the NF-kappaB signaling pathway
    • Mazzone, G.L., I. Rigato, J.D. Ostrow and C.Tiribelli: Bilirubin effect on endothelial adhesion molecules expression is mediated by the NF-kappaB signaling pathway. Biosci Trends 3, 151-157 (2009)
    • (2009) Biosci Trends , vol.3 , pp. 151-157
    • Mazzone, G.L.1    Rigato, I.2    Ostrow, J.D.3    Tiribelli, C.4
  • 63
    • 0042763565 scopus 로고    scopus 로고
    • Induction of heme oxygenase-1 in monocytes suppresses angiotensin II-elicited chemotactic activity through inhibition of CCR2: Role of bilirubin and carbon monoxide generated by the enzyme
    • Morita, T., T. Imai, T. Yamaguchi, T. Sugiyama, S. Katayama and G. Yoshino: Induction of heme oxygenase- 1 suppresses angiotensin II-elicited chemotactic activity through inhibition of CCR2: role of bilirubin and carbon monoxide generated by the enzyme. Antioxid Redox Signal 5, 439-447 (2003) (Pubitemid 37087404)
    • (2003) Antioxidants and Redox Signaling , vol.5 , Issue.4 , pp. 439-447
    • Morita, T.1    Imai, T.2    Yamaguchi, T.3    Sugiyama, T.4    Katayama, S.5    Yoshino, G.6
  • 65
    • 23044459608 scopus 로고    scopus 로고
    • Carbon monoxide-releasing molecules (CO-RMs) attenuate the inflammatory response elicited by lipopolysaccharide in RAW264.7 murine macrophages
    • DOI 10.1038/sj.bjp.0706241
    • Sawle, P., R. Foresti, B.E. Mann, T.R. Johnson, C.J. Green and R. Motterlini: Carbon monoxide-releasing molecules (CO-RMs) attenuate the inflammatory response elicited by lipopolysaccharide in RAW264.7 murine macrophages. Br J Pharmacol 145, 800-810 (2005) (Pubitemid 41076287)
    • (2005) British Journal of Pharmacology , vol.145 , Issue.6 , pp. 800-810
    • Sawle, P.1    Foresti, R.2    Mann, B.E.3    Johnson, T.R.4    Green, C.J.5    Motterlini, R.6
  • 66
    • 0034071424 scopus 로고    scopus 로고
    • Carbon monoxide has anti-inflammatory effects involving the mitogen- activated protein kinase pathway
    • DOI 10.1038/74680
    • Otterbein, L.E., F.H. Bach, J. Alam, M.P. Soares, H. Tao Lu, M. Wysk, R.J. Davis, R.A. Flavell and A.M. Choi: Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway. Nat Med 6, 422-428 (2000) (Pubitemid 30208159)
    • (2000) Nature Medicine , vol.6 , Issue.4 , pp. 422-428
    • Otterbein, L.E.1    Bach, F.H.2    Alam, J.3    Soares, M.4    Lu, H.T.5    Wysk, M.6    Davis, R.J.7    Flavell, R.A.8    Choi, A.M.K.9
  • 67
    • 65449130775 scopus 로고    scopus 로고
    • The heme oxygenase-1/carbon monoxide pathway suppresses TLR4 signaling by regulating the interaction of TLR4 with caveolin-1
    • Wang X.M., H.P. Kim, K. Nakahira, S.W. Ryter and A.M.K. Choi: The heme oxygenase-1/carbon monoxide pathway suppresses TLR4 signaling by regulating the interaction of TLR4 with caveolin-1. J Immunol 182, 3809-3818 (2009)
    • (2009) J Immunol , vol.182 , pp. 3809-3818
    • Wang, X.M.1    Kim, H.P.2    Nakahira, K.3    Ryter, S.W.4    Choi, A.M.K.5
  • 69
    • 65249113865 scopus 로고    scopus 로고
    • Heme oxygenase-1 contributes to an alternative macrophage activation profile induced by apoptotic cell supernatants
    • Weis, N., A. Weigert, A. von Knethen and B. Brune: Heme oxygenase-1 contributes to an alternative macrophage activation profile induced by apoptotic cell supernatants. Mol Biol Cell 20, 1280-1288 (2009)
    • (2009) Mol Biol Cell , vol.20 , pp. 1280-1288
    • Weis, N.1    Weigert, A.2    Von Knethen, A.3    Brune, B.4
  • 72
    • 0036127426 scopus 로고    scopus 로고
    • Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice
    • DOI 10.1038/nm0302-240
    • Lee, T.-S. and L.-Y. Chau: Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice. Nat Med 8, 240-246 (2002) (Pubitemid 34250101)
    • (2002) Nature Medicine , vol.8 , Issue.3 , pp. 240-246
    • Lee, T.-S.1    Chau, L.-Y.2
  • 74
    • 0034737984 scopus 로고    scopus 로고
    • Relation between endothelial cell apoptosis and blood flow direction in human atherosclerotic plaques
    • Tricot, O., Z. Mallat, C. Heymes, J. Belmin, G. Leseche and A. Tedgui: Relation between endothelial cell apoptosis and blood direction in human atherosclerotic plaques. Circulation 101, 2450-2453 (2000) (Pubitemid 30366245)
    • (2000) Circulation , vol.101 , Issue.21 , pp. 2450-2453
    • Tricot, O.1    Mallat, Z.2    Heymes, C.3    Belmin, J.4    Leseche, G.5    Tedgui, A.6
  • 75
    • 67349252035 scopus 로고    scopus 로고
    • Heme oxygenase-1, a critical arbitrator of cell death pathways in lung injury and disease
    • Morse, D., L. Lin, A.M. Choi and S.W. Ryter: Heme oxygenase-1, a critical arbitrator of cell death pathways in lung injury and disease. Free Radic Biol Med 47, 1-12 (2009)
    • (2009) Free Radic Biol Med , vol.47 , pp. 1-12
    • Morse, D.1    Lin, L.2    Choi, A.M.3    Ryter, S.W.4
  • 78
    • 0036067762 scopus 로고    scopus 로고
    • Carbon monoxide inhibits apoptosis in vascular smooth muscle cells
    • DOI 10.1016/S0008-6363(02)00410-8, PII S0008636302004108
    • Liu, X.M., G.B. Chapman, K.J. Peyton, A.I. Schafer and W. Durante: Carbon monoxide inhibits apoptosis in vascular smooth muscle cells. Cardiovasc Res 55, 396-405 (2002) (Pubitemid 34775290)
    • (2002) Cardiovascular Research , vol.55 , Issue.2 , pp. 396-405
    • Liu, X.-M.1    Chapman, G.B.2    Peyton, K.J.3    Schafer, A.I.4    Durante, W.5
  • 80
    • 33748469506 scopus 로고    scopus 로고
    • Apoptosis of vascular smooth muscle cells induces features of plaque vulnerability in atherosclerosis
    • DOI 10.1038/nm1459, PII NM1459
    • Clarke, M.C., N. Figg, J.J. Maguire, A.P. Davenport, M. Goddard and T.D. Littlewood: Apoptosis of vascular smooth muscle cells induces features of plaque vulnerability in atherosclerosis. Nat Med 12, 1075-1080 (2006) (Pubitemid 44353389)
    • (2006) Nature Medicine , vol.12 , Issue.9 , pp. 1075-1080
    • Clarke, M.C.H.1    Figg, N.2    Maguire, J.J.3    Davenport, A.P.4    Goddard, M.5    Littlewood, T.D.6    Bennett, M.R.7
  • 82
    • 50949120932 scopus 로고    scopus 로고
    • Inhibition of dendritic cell maturation and function is independent of heme oxygenase-1 but requires the activation of STAT3
    • Mashreghi, M.F., R. Klemz, I.S. Knosalla, B, Gerstmayer, U. Janssen, R. Buelow, A. Jozkowicz, J. Dulak, H.D. Volk and K. Kotsch: Inhibition of dendritic cell maturation and function is independent of heme oxygenase-1 but requires the activation of STAT3. J Immunol 180, 7919-7930 (2008)
    • (2008) J Immunol , vol.180 , pp. 7919-7930
    • Mashreghi, M.F.1    Klemz, R.2    Knosalla, B.I.S.3    Janssen, G.U.4    Buelow, R.5    Jozkowicz, A.6    Dulak, J.7    Volk, H.D.8    Kotsch, K.9
  • 83
    • 77953210092 scopus 로고    scopus 로고
    • + dendritic cell differentiation in vivo
    • Park, D.J., A. Agarwal and J.F. George: Heme oxygenase-1 expression in murine dendritic cell subpopulations: effect on CD8+ dendritic cell differentiation in vivo. Am J Pathol 176, 2831-2839 (2010)
    • (2010) Am J Pathol , vol.176 , pp. 2831-2839
    • Park, D.J.1    Agarwal, A.2    George, J.F.3
  • 86
    • 49649097976 scopus 로고    scopus 로고
    • Bilirubin possesses powerful immunomodulatory activity and suppresses experimental autoimmune encephalomyelitis
    • Liu, Y., P. Li, J. Lu, W. Xiong, J. Oger, W. Tetzlaff and M. Cynader: Bilirubin possesses powerful immunomodulatory activity and suppresses experimental autoimmune encephalomyelitis. J Immunol 181, 1887-1897 (2008)
    • (2008) J Immunol , vol.181 , pp. 1887-1897
    • Liu, Y.1    Li, P.2    Lu, J.3    Xiong, W.4    Oger, J.5    Tetzlaff, W.6    Cynader, M.7
  • 89
    • 1842529311 scopus 로고    scopus 로고
    • Carbon monoxide produced by heme oxygenase-1 suppresses T cell proliferation via inhibition of IL-2 production
    • Pae, H.O., G.S. Ho, B.M. Choi, S.C. Chae, Y.M. Kim, K.R. Chung and H.T. Chung: Carbon monoxide produced by heme oxygenase-1 suppresses T cell proliferation via inhibition of IL-2 production. J Immunol 172, 4744-4751 (2004)
    • (2004) J Immunol , vol.172 , pp. 4744-4751
    • Pae, H.O.1    Ho, G.S.2    Choi, B.M.3    Chae, S.C.4    Kim, Y.M.5    Chung, K.R.6    Chung, H.T.7
  • 91
    • 14644435685 scopus 로고    scopus 로고
    • Heme oxygenase-1 modulates the allo-immune response by promoting activation-induced cell death of T cells
    • DOI 10.1096/fj.04-2217fje
    • McDaid, J., K. Yamashita, A. Chora, R. Ollinger, T.B. Strom, X.C. Li, F.H. Bach and M.P. Soares: Heme oxygenase-1 modulates the alloimune response by promoting activation-induced cell death of T cells. FASEB J 19, 458-460 (2005) (Pubitemid 40316549)
    • (2005) FASEB Journal , vol.19 , Issue.3 , pp. 458-460
    • McDaid, J.1    Yamashita, K.2    Chora, A.3    Ollinger, R.4    Strom, T.B.5    Li, X.C.6    Bach, F.H.7    Soares, M.P.8
  • 93
    • 0019857806 scopus 로고
    • Mitogenic and co-mitogenic properties of hemin
    • Stenzel, K.H., A.L. Rubin and A. Novogrodsky: Mitogenic and co-mitogenic properties of hemin. J Immunol 127, 2469-2473 (1981) (Pubitemid 12245843)
    • (1981) Journal of Immunology , vol.127 , Issue.6 , pp. 2469-2473
    • Stenzel, K.H.1    Rubin, A.L.2    Novogrodsky, A.3
  • 94
    • 0035087058 scopus 로고    scopus 로고
    • Heme oxygenase-1 gene therapy: A novel immunomodulatory approach in liver allograft recipients?
    • DOI 10.1016/S0041-1345(00)02151-5, PII S0041134500021515
    • Ke, B., R. Buelow, X.D. Shen, J. Milinek, F. Gao, T. Ritter, H.D. Volk, R.W. Busuttil and J.W. Kupiec-Weglinski: Heme oxgenase-1 gene therapy: a novel immunological approach in liver allograft recipients. Transplant Proc 33, 581-582 (2001) (Pubitemid 32237523)
    • (2001) Transplantation Proceedings , vol.33 , Issue.1-2 , pp. 581-582
    • Ke, B.1
  • 95
    • 0036019201 scopus 로고    scopus 로고
    • Heme oxygenase 1 gene transfer prevents CD95/Fas ligand-mediated apoptosis and improves liver allograft survival via carbon monoxide signaling pathway
    • DOI 10.1089/104303402320138970
    • Ke, B., R. Buelow, X.D. Shen, J. Melinik, F. Amersi, F. Gao, T. Ritter, H.D. Volk, R.W. Busuttil and J.W. Kupiec- Weglinski: Heme oxygenase 1 gene transfer prevents CD95/Fas lignd-mediated apoptosis and improves liver allograft survival via carbon monoxide signaling pathway. Hum Gene Ther 13, 1189-1199 (2002) (Pubitemid 34746699)
    • (2002) Human Gene Therapy , vol.13 , Issue.10 , pp. 1189-1199
    • Ke, B.1    Buelow, R.2    Shen, X.-D.3    Melinek, J.4    Amersi, F.5    Gao, F.6    Ritter, T.7    Volk, H.-D.8    Busuttil, R.W.9    Kupiec-Weglinski, J.W.10
  • 97
    • 33845901771 scopus 로고    scopus 로고
    • Heme oxygenase-1 is not required for mouse regulatory T cell development and function
    • DOI 10.1093/intimm/dxl116
    • Zelenay, S., A. Chora, M.P. Soares and J. Demengeot: Heme oxygenase-1 is not required for mouse regulatory T-cell development and function. Int Immunol 19, 11-18 (2007) (Pubitemid 46017883)
    • (2007) International Immunology , vol.19 , Issue.1 , pp. 11-18
    • Zelenay, S.1    Chora, A.2    Soares, M.P.3    Demengeot, J.4
  • 100
    • 34248531976 scopus 로고    scopus 로고
    • Perivascular mast cells promote atherogenesis and induce plaque destabilization in apolipoprotein E-deficient mice
    • DOI 10.1161/CIRCULATIONAHA.106.660472
    • Bot. I., S.C. de Jager, A. Zernecke, K.A. Lindstedt, T. J. van Berkel, C. Weber and E.A. Biessen: Perivascular mast cells promote atherogenesis and induce plaque destabilization in apolipoprotein E-deficient mice. Circulation 115, 2516-2525 (2007) (Pubitemid 46763225)
    • (2007) Circulation , vol.115 , Issue.19 , pp. 2516-2525
    • Bot, I.1    De Jager, S.C.A.2    Zernecke, A.3    Lindstedt, K.A.4    Van Berkel, T.J.C.5    Weber, C.6    Biessen, E.A.L.7
  • 103
    • 75649130466 scopus 로고    scopus 로고
    • Platelets and innate immunity
    • Semple, J.W. and J. Freedman: Platelets and innate immunity. Cell Mol Life Sci 67, 499-511 (2010)
    • (2010) Cell Mol Life Sci , vol.67 , pp. 499-511
    • Semple, J.W.1    Freedman, J.2
  • 104
    • 0021248847 scopus 로고
    • Inhibition of platelet ADP and serotonin release by carbon monoxide and in cigarette smokers
    • Mansouri, A and C.A. Perry: Inhibition of platelet ADP and serotonin release by carbon monoxide. Experentia 40, 515-517 (1984) (Pubitemid 14096265)
    • (1984) Experientia , vol.40 , Issue.5 , pp. 515-517
    • Mansouri, A.1    Perry, C.A.2
  • 105
    • 0023490534 scopus 로고
    • Inhibition of platelet aggregation by carbon monoxide is mediated by activation of guanylate cyclase
    • Brune, B and V. Ullrich: Inhibition of platelet aggregation by carbon monoxide is mediated by activation of guanylate cyclase. Mol Pharmacol 32, 497-504 (1987) (Pubitemid 18006150)
    • (1987) Molecular Pharmacology , vol.32 , Issue.4 , pp. 497-504
    • Brune, B.1    Ullrich, V.2
  • 107
    • 33745449736 scopus 로고    scopus 로고
    • Carbon monoxide released by CORM-3 inhibits human platelets by a mechanism independent of soluble guanylate cyclase
    • DOI 10.1016/j.cardiores.2006.03.011, PII S0008636306001179
    • Chlopicki, S., R. Olszanecki, E. Marcinkiewicz, M. Lomnicka and R. Motterlini: Carbon monoxide release by CORM-3 inhibits human platelets by a mechanism independent of soluble guanylate cyclase. Cardiovas Res 71, 393-401 (2006) (Pubitemid 43949260)
    • (2006) Cardiovascular Research , vol.71 , Issue.2 , pp. 393-401
    • Chlopicki, S.1    Olszanecki, R.2    Marcinkiewicz, E.3    Lomnicka, M.4    Motterlini, R.5
  • 108
    • 0036725032 scopus 로고    scopus 로고
    • Carbon monoxide modulates endotoxin-induced microvascular leukocyte adhesion through platelet-dependent mechanisms
    • DOI 10.1097/00000542-200209000-00025
    • Morisaki, H., T. Katayama, Y. Kotake, M. Ito, M. Handa, Y. Ikeda, J. Takeda and M. Suematsu: Carbon monoxide modulates endotoxin-induced microvascular leukocyte adhesion through platelet-dependent mechanisms. Anesthesiology 97, 701-709 (2002) (Pubitemid 34977331)
    • (2002) Anesthesiology , vol.97 , Issue.3 , pp. 701-709
    • Morisaki, H.1    Katayama, T.2    Kotake, Y.3    Ito, M.4    Handa, M.5    Ikeda, Y.6    Takeda, J.7    Suematsu, M.8
  • 111
    • 37349070339 scopus 로고    scopus 로고
    • Heme oxygenase-1 deficiency accelerates formation of arterial thrombosis through oxidative damage to the endothelium, which is rescued by inhaled carbon monoxide
    • DOI 10.1161/CIRCRESAHA.107.158998
    • True, A.L., M. Olive, M. Boehm, H. San, R.J. Westrick, N. Raghavachari, X. Xu, E.G. Lynn, M.N. Sack, P.J. Munson,M.T. Gladwin and E.G. Nabel: Heme oxygenase-1 deficiency accelerates formation of arterial thrombosis through oxidative damage to the endothelium, which is rescued by inhaled carbon monoxide. Circ Res 101, 893-901 (2007) (Pubitemid 350287176)
    • (2007) Circulation Research , vol.101 , Issue.9 , pp. 893-901
    • True, A.L.1    Olive, M.2    Boehm, M.3    San, H.4    Westrick, R.J.5    Raghavachari, N.6    Xu, X.7    Lynn, E.G.8    Sack, M.N.9    Munson, P.J.10    Gladwin, M.T.11    Nabel, E.G.12
  • 113
    • 67649947461 scopus 로고    scopus 로고
    • Carbon monoxide rescues heme oxygenase-1-deficient mice from arterial thrombosis in allogeneic aortic transplantation
    • Chen, B., L. Guo, C. Fan, S. Bolisetty, R. Joseph, M.W. Wright, A. Agarwal and J.F. George: Carbon monoxide rescues heme oxygenase-1-deficient mice from arterial thrombosis in allogeneic aortic transplantation. Am J Pathol 175, 422-429 (2009)
    • (2009) Am J Pathol , vol.175 , pp. 422-429
    • Chen, B.1    Guo, L.2    Fan, C.3    Bolisetty, S.4    Joseph, R.5    Wright, M.W.6    Agarwal, A.7    George, J.F.8
  • 116
    • 0037181417 scopus 로고    scopus 로고
    • Treatment of recurrent allograft dysfunction with intravenous hematin after liver transplantation for erythropoietic protoporphyria
    • Dellon, E.S., Z.M. Szczepiorkowski, W.H. Dzik, F. Graeme-Cook, A. Ades, J.R. Bloomer, A.B. Cosimi and R.T. Chung: Treatment of recurrent allograft dysfunction with intravenous hematin after liver transplantation for erythropoietic protoporphyria. Transplantation 73, 911-915 (2002) (Pubitemid 34252354)
    • (2002) Transplantation , vol.73 , Issue.6 , pp. 911-915
    • Dellon, E.S.1    Szczepiorkowski, Z.M.2    Dzik, W.H.3    Graeme-Cook, F.4    Ades, A.5    Bloomer, J.R.6    Cosimi, A.B.7    Chung, R.T.8
  • 119
    • 27644584482 scopus 로고    scopus 로고
    • L-methionine reduces oxidant stress in endothelial cells: Role of heme oxygenase-1, ferritin, and nitric oxide
    • DOI 10.1208/aapsj070118, 18
    • Erdmann, K., N. Grosser and H. Schroder: Lmethionine reduces oxidant stress in endothelial cells: role of heme oxygenase-1, ferritin, and nitric oxide. AAPS J 7:E195-E200 (2005) (Pubitemid 41554289)
    • (2005) AAPS Journal , vol.7 , Issue.1
    • Erdmann, K.1    Grosser, N.2    Schroder, H.3
  • 121
    • 13444279864 scopus 로고    scopus 로고
    • The lower intestinal tract-specific induction of heme oxygenase-1 by glutamine protects against endotoxemic intestinal injury
    • DOI 10.1097/01.CCM.0000153407.14237.7F
    • Uehara, K., T. Takahashi, H. Fujii, H. Shimizu, E. Omori, M. Matsumi, M. Yokoyama, K. Morita, T. Akagi and S. Sassa: The lower intestinal tract-specific induction of heme oxygenase-1 by glutamine protects against endotoxemic intestinal injury. Crit Care Med 33, 381-390 (2005) (Pubitemid 40216553)
    • (2005) Critical Care Medicine , vol.33 , Issue.2 , pp. 381-390
    • Uehara, K.1    Takahashi, T.2    Fujii, H.3    Shimizu, H.4    Omori, E.5    Matsumi, M.6    Yokoyama, M.7    Morita, K.8    Akagi, R.9    Sassa, S.10
  • 122
    • 0027987849 scopus 로고
    • Randomized trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S)
    • Randomized trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S). Lancet 344, 1383-1389 (1994)
    • (1994) Lancet , vol.344 , pp. 1383-1389
  • 123
    • 11344279659 scopus 로고    scopus 로고
    • Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis in Myocardial Infarction 22 (PROVE IT-TIMI 22) Investigators: C-reactive protein levels and outcomes after statin therapy
    • Ridker, P.M., C.P. Cannon, D. Morrow, N. Rifai, L.M. Rose, C.H. McCabe, M.A. Pfeffer and E. Braunwald: Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis in Myocardial Infarction 22 (PROVE IT-TIMI 22) Investigators: C-reactive protein levels and outcomes after statin therapy. N Engl J Med 352, 20-28 (2005)
    • (2005) N Engl J Med , vol.352 , pp. 20-28
    • Ridker, P.M.1    Cannon, C.P.2    Morrow, D.3    Rifai, N.4    Rose, L.M.5    McCabe, C.H.6    Pfeffer, M.A.7    Braunwald, E.8
  • 126
    • 4444369432 scopus 로고    scopus 로고
    • Simvastatin induces heme oxygenase-1: A novel mechanism of vessel protection
    • DOI 10.1161/01.CIR.0000140694.67251.9C
    • Lee, T.S., C.C. Chang, Y. Zhu and J.Y. Shyy: Simvastatin induces heme oxygenase-1: a novel mechanism of vessel protection. Circulation 110, 1296-1302 (2004). (Pubitemid 39202348)
    • (2004) Circulation , vol.110 , Issue.10 , pp. 1296-1302
    • Lee, T.-S.1    Chang, C.-C.2    Zhu, Y.3    Shyy, J.Y.-J.4
  • 128
    • 67650523965 scopus 로고    scopus 로고
    • Induction of the cytoprotective enzyme heme oxygenase-1 by statins is enhanced in vascular endothelium exposed to laminar shear stress and impaired by disturbed flow
    • Ali, F., M. Zakkar, K. Karu, E.A. Lidington, S.S. Hamdulay, J.J. Boyle, M. Zloh, A. Bauer, D.O. Haskard, P.C. Evans and J.C. Mason: Induction of the cytoprotective enzyme heme oxygenase-1 by statins is enhanced in vascular endothelium exposed to laminar shear stress and impaired by disturbed flow. J Biol Chem 284, 18882-18892 (2009)
    • (2009) J Biol Chem , vol.284 , pp. 18882-18892
    • Ali, F.1    Zakkar, M.2    Karu, K.3    Lidington, E.A.4    Hamdulay, S.S.5    Boyle, J.J.6    Zloh, M.7    Bauer, A.8    Haskard, D.O.9    Evans, P.C.10    Mason, J.C.11
  • 129
    • 33744782329 scopus 로고    scopus 로고
    • Atorvastatin prevents hypoxia-induced inhibition of endothelial nitric oxide synthase expression but does not affect heme oxygenase-1 in human microvascular endothelial cells
    • DOI 10.1016/j.atherosclerosis.2006.03.015, PII S0021915006001456
    • Loboda, A., A. Jazwa, A. Jozkowicz, J. Dorosz, J. Balla, G. Molema and J. Dulak: Atorvastatin prevents hypoxiainduced inhibition of endothelial nitric oxide synthase expression but does not affect heme oxygenase-1 in human microvascular endothelial cells. Atherosclerosis 187, 26-30 (2006) (Pubitemid 43833360)
    • (2006) Atherosclerosis , vol.187 , Issue.1 , pp. 26-30
    • Loboda, A.1    Jazwa, A.2    Jozkowicz, A.3    Dorosz, J.4    Balla, J.5    Molema, G.6    Dulak, J.7
  • 130
    • 0037138578 scopus 로고    scopus 로고
    • Effects of probucol and pravastatin on common carotid atherosclerosis in patients with asymptomatic hypercholesterolemia: Fukuoka atherosclerosis trial (FAST)
    • DOI 10.1016/S0735-1097(01)01783-1, PII S0735109701017831
    • Sawayama, Y., C. Shimizu, N. Maeda, M. Tatsukawa, N. Kinukawa, S. Koyanagi, S. Kashiwagi and J. Hayashi: Effect of probucol and pravastin on common carotid atherosclerosis in patients with asymptomatic hypercholesterolemia: Fukuoka Atherosclerosis Trial (FAST). J Am Coll Cardiol 39, 610-616 (2002) (Pubitemid 34158156)
    • (2002) Journal of the American College of Cardiology , vol.39 , Issue.4 , pp. 610-616
    • Sawayama, Y.1    Shimizu, C.2    Maeda, N.3    Tatsukawa, M.4    Kinukawa, N.5    Koyanagi, S.6    Kashiwagi, S.7    Hayashi, J.8
  • 132
    • 4644290036 scopus 로고    scopus 로고
    • Probucol protects against smooth muscle cell proliferation by upregulating heme oxygenase-1
    • DOI 10.1161/01.CIR.0000142610.10530.25
    • Deng, Y.M., B.J. Wu, P.K. Witting and R. Stocker: Probucol protects against smooth muscle cell proliferation by upregulating heme oxygenase-1. Circulation 110, 1855-1860 (2004) (Pubitemid 39299229)
    • (2004) Circulation , vol.110 , Issue.13 , pp. 1855-1860
    • Deng, Y.-M.1    Wu, B.J.2    Witting, P.K.3    Stocker, R.4
  • 135
    • 0037448802 scopus 로고    scopus 로고
    • Rapamycin induces heme oxygenase-1 in human pulmonary vascular cells: Implications in the antiproliferative response to rapamycin
    • DOI 10.1161/01.CIR.0000048191.75585.60
    • Visner, G.A., F. Lu, H. Zhou, J. Liu, K. Kazemfar and A. Agarwal: Rapamycin induces heme oxygenase-1 in human pulmonary vascular cells: implications in the antiproliferative response to rapamycin. Circulation 107,
    • (2003) Circulation , vol.107 , Issue.6 , pp. 911-916
    • Visner, G.A.1    Lu, F.2    Zhou, H.3    Liu, J.4    Kazemfar, K.5    Agarwal, A.6
  • 136
    • 32844465285 scopus 로고    scopus 로고
    • Heme oxygenase-1 mediates the protective effects of rapamycin in monocrotaline-induced pulmonary hypertension
    • DOI 10.1038/labinvest.3700361, PII 3700361
    • Zhou, H., H. Liu, S.L. Porvasnik, N. Terada, A. Agarwal, Y. Cheng and G.A. Visner: Heme oxygenase-1 mediates the protective effects of rapamycin in monocrotaline-induced pulmonary hypertension. Lab Invest 86, 62-71 (2006) (Pubitemid 43250969)
    • (2006) Laboratory Investigation , vol.86 , Issue.1 , pp. 62-71
    • Zhou, H.1    Liu, H.2    Porvasnik, S.L.3    Terada, N.4    Agarwal, A.5    Cheng, Y.6    Visner, G.A.7
  • 137
    • 27144499220 scopus 로고    scopus 로고
    • Induction of heme oxygenase-1 is involved in the antiproliferative effects of paclitaxel in rat vascular smooth muscle cells
    • Choi, B.M., Y.M. Kim, Y.R. Jeong, H.O. Pae, C.E. Song, J.E. Park, Y.K. Ahn and H.T. Chung: Induction of heme oxygenase-1 is involved in the antiproliferative effects of paclitaxel in rat vascular smooth muscle cells. Biochem Biophys Res Commun 25, 39-47 (2004)
    • (2004) Biochem Biophys Res Commun , vol.25 , pp. 39-47
    • Choi, B.M.1    Kim, Y.M.2    Jeong, Y.R.3    Pae, H.O.4    Song, C.E.5    Park, J.E.6    Ahn, Y.K.7    Chung, H.T.8
  • 138
    • 0036140786 scopus 로고    scopus 로고
    • Adenovirus-mediated heme oxygenase-1 gene expression stimulates apoptosis in vascular smooth muscle cells
    • DOI 10.1161/hc0102.101369
    • Liu, X.M., G.B. Chapman, H. Wang, and W. Durante: Adenovirus-mediated heme oxygenase-1 gene expression stimulates apoptosis in vascular smooth muscle cells. Circulation 105, 79-84 (2002) (Pubitemid 34049146)
    • (2002) Circulation , vol.105 , Issue.1 , pp. 79-84
    • Liu, X.-M.1    Chapman, G.B.2    Wang, H.3    Durante, W.4
  • 139
    • 0032827423 scopus 로고    scopus 로고
    • Reversal of HO-1 related cytoprotection with increased expression is due to reactive iron
    • Suttner, D.M and P.A. Dennery: Reversal of HO-1 related cytoprotection with increased expression due to reactive iron. FASEB J 13, 1800-1809 (1999) (Pubitemid 29473342)
    • (1999) FASEB Journal , vol.13 , Issue.13 , pp. 1800-1809
    • Suttner, D.M.1    Dennery, P.A.2
  • 140
    • 4644226200 scopus 로고    scopus 로고
    • The role of heme oxygenase-1 promoter polymorphisms in human disease
    • DOI 10.1016/j.freeradbiomed.2004.07.008, PII S0891584904005477
    • Exner, M., E. Minar, O. Wagner and M. Schillinger: The role of heme oxygenase-1 promoter polymorphisms in human disease. Free Radic Biol Med 37, 1097-1104 (2004) (Pubitemid 39296737)
    • (2004) Free Radical Biology and Medicine , vol.37 , Issue.8 , pp. 1097-1104
    • Exner, M.1    Minar, E.2    Wagner, O.3    Schillinger, M.4
  • 142
    • 0035960644 scopus 로고    scopus 로고
    • Adenovirus-mediated heme oxygenase-1 gene delivery inhibits injury-induced vascular neointima formation
    • Tulis, D.A, W. Durante, X. Liu, A.J. Evan, K.J Peyton and A.I. Schafer: Adenovirus-mediated heme oxygenase-1 gene delivery inhibits injury-induced vascular neointima formation. Circulation 104, 2710-2715 (2001) (Pubitemid 33108139)
    • (2001) Circulation , vol.104 , Issue.22 , pp. 2710-2715
    • Tulis, D.A.1    Durante, W.2    Liu, X.3    Evans, A.J.4    Peyton, K.J.5    Schafer, A.I.6
  • 143
    • 34247615614 scopus 로고    scopus 로고
    • Heme oxygenase -1 gene therapy: Recent advances and therapeutic applications
    • DOI 10.2174/156652307780363134
    • Abraham, N.G., A. Asija, G. Drummond and S. Peterson: Heme oxygenase-1 gene therapy: recent advances and therapeutic applications. Curr Gene Ther 7, 89-108 (2007) (Pubitemid 46681767)
    • (2007) Current Gene Therapy , vol.7 , Issue.2 , pp. 89-108
    • Abraham, N.G.1    Asija, A.2    Drummond, G.3    Peterson, S.4
  • 147
    • 11244279637 scopus 로고    scopus 로고
    • Inhalation of carbon monoxide prevents liver injury and inflammation following hind limb ischemia/reperfusion
    • DOI 10.1096/fj.04-2514fje
    • Ott, M.C., J. R. Scott, A. Bihari, A. Badhwar, L.E. Otterbein, D.K. Gray, K.A. Harris and R.F. Potter : Inhalation of carbon monoxide prevents liver injury and inflammation following hindlimb ischemia/reperfusion. FASEB J 19, 106-108 (2005) (Pubitemid 40069933)
    • (2005) FASEB Journal , vol.19 , Issue.1 , pp. 106-108
    • Ott, M.C.1    Scott, J.R.2    Bihari, A.3    Badhwar, A.4    Otterbein, L.E.5    Gray, D.K.6    Harris, K.A.7    Potter, R.F.8
  • 148
    • 75149121714 scopus 로고    scopus 로고
    • Carbon monoxide now orphan drug for transplantation
    • Carbon monoxide now orphan drug for transplantation. Inpharma 1, 21 (2008)
    • (2008) Inpharma , vol.1 , pp. 21
  • 151
    • 27144498992 scopus 로고    scopus 로고
    • Local administration of carbon monoxide inhibits neointima formation in balloon injured rat carotid arteries
    • DOI 10.1170/T648
    • Tulis, D.A., A.N. Keswani, K.J. Peyton, H. Wang, A.I. Schafer and W. Durante. Local administration of carbon monoxide inhibits neointima formation in balloon injured rat carotid arteries. Cell Mol Biol (Noisy-le-grand) 51, 441-446 (2005) (Pubitemid 41596300)
    • (2005) Cellular and Molecular Biology , vol.51 , Issue.5 , pp. 441-446
    • Tulis, D.A.1    Keswani, A.N.2    Peyton, K.J.3    Wang, H.4    Schafer, A.I.5    Durante, W.6
  • 153
    • 27744453772 scopus 로고    scopus 로고
    • Reviewing the use of carbon monoxide-releasing molecules (CO-RMs) in biology: Implications in endotoxin-mediated vascular dysfunction
    • DOI 10.1170/T645
    • Foresti, R., C. Shurey, T. Ansari, P. Sibbons, B.E. Mann, T.R. Johnson, C.J. Green and R. Motterlini: Reviewing the use of carbon monoxide-releasing molecules (CO-RMs) in biology: implications in endotoxin-mediated vascular dysfunction. Cell Mol Biol (Noisy-le-grand) 51, 409-423 (2005) (Pubitemid 41596319)
    • (2005) Cellular and Molecular Biology , vol.51 , Issue.4 , pp. 409-423
    • Foresti, R.1    Shurey, C.2    Ansari, T.3    Sibbons, P.4    Mann, B.E.5    Johnson, T.R.6    Green, C.J.7    Motterlini, R.8
  • 154
    • 75449111586 scopus 로고    scopus 로고
    • Hemin prevents in-stent stenosis in rat and rabbit models by inducing heme oxygenase-1
    • Hyvelin, J.M., B. Maurel, R. Uzbekov, R. Motterlini and P. Lermusiaux: Hemin prevents in-stent stenosis in rat and rabbit models by inducing heme oxygenase-1. J Vasc Res 51, 417-428 (2010)
    • (2010) J Vasc Res , vol.51 , pp. 417-428
    • Hyvelin, J.M.1    Maurel, B.2    Uzbekov, R.3    Motterlini, R.4    Lermusiaux, P.5
  • 156
    • 23044447945 scopus 로고    scopus 로고
    • Biliverdin administration prevents the formation of intimal hyperplasia induced by vascular injury
    • DOI 10.1161/CIRCULATIONAHA.104.509778
    • Nakao, A., N. Murase, C. Ho, B. Toyokawa, T.R. Billiar and S. Kanno: Biliverdin administration prevents the formation of intimal hyperplasia induced by vascular injury. Circulation 112, 587-591 (2005) (Pubitemid 41060800)
    • (2005) Circulation , vol.112 , Issue.4 , pp. 587-591
    • Nakao, A.1    Murase, N.2    Ho, C.3    Toyokawa, H.4    Billiar, T.R.5    Kanno, S.6
  • 157
    • 0028084319 scopus 로고
    • Association of low serum concentration of bilirubin with increased risk of coronary artery disease
    • Schwertner, H.A., W.G. Jackson and G. Tolan: Association of low serum concentration of bilirubin with increased risk of coronary artery disease. Clin Chem 40, 18-23 (1994) (Pubitemid 24050206)
    • (1994) Clinical Chemistry , vol.40 , Issue.1 , pp. 18-23
    • Schwertner, H.A.1    Jackson, W.G.2    Tolan, G.3
  • 158


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