Perivascular mast cells promote atherogenesis and induce plaque destabilization in apolipoprotein E-deficient mice

Circulation

Volumn 115, Issue 19, 2007, Pages 2516-2525

  Bot, Ilze ^a   De Jager, Saskia C A ^a   Zernecke, Alma ^b   Lindstedt, Ken A ^c   Van Berkel, Theo J C ^a   Weber, Christian ^b   Biessen, Erik A L ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

^b UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^c WIHURI RESEARCH INSTITUTE   (Finland)

Author keywords

Apoptosis; Atherosclerosis; Hemorrhage; Inflammation; Mast cells

Indexed keywords

APOLIPOPROTEIN E; CHEMOKINE RECEPTOR CXCR2; CROMOGLYCATE DISODIUM; VERY LATE ACTIVATION ANTIGEN 4;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; BLEEDING; CELL ACTIVATION; CONTROLLED STUDY; DISEASE COURSE; HYPERLIPOPROTEINEMIA TYPE 3; MACROPHAGE; MALE; MAST CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; APOLIPOPROTEINS E; APOPTOSIS; CAPILLARY PERMEABILITY; CAROTID ARTERY DISEASES; CELLS, CULTURED; CHEMOTAXIS, LEUKOCYTE; CROMOLYN SODIUM; DINITROPHENOLS; DISEASE PROGRESSION; HEMORRHAGE; HUMANS; HYPERLIPOPROTEINEMIA TYPE II; INFLAMMATION; INTEGRIN ALPHA4BETA1; MACROPHAGES; MALE; MAST CELLS; MICE; MICE, KNOCKOUT; MODELS, BIOLOGICAL; RECEPTORS, INTERLEUKIN-8B; SERUM ALBUMIN, BOVINE; TRYPTASES;

EID: 34248531976     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.106.660472     Document Type: Article

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