Antiapoptotic action of carbon monoxide on cultured vascular smooth muscle cells

Experimental Biology and Medicine

Volumn 228, Issue 5, 2003, Pages 572-575

  Liu, Xiao Ming ^a   Chapman, Gary B ^a   Peyton, Kelly J ^a   Schafer, Andrew I ^a   Durante, William ^a,b  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b Medical Center Building 109   (United States)

Author keywords

Cell cycle; Cell death; Circulation

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CARBON MONOXIDE; CASPASE 3; CYCLIC GMP; DNA; GAMMA INTERFERON; GUANYLATE CYCLASE INHIBITOR; HEME; HEME OXYGENASE; INTERLEUKIN 1BETA; LIPOCORTIN 5; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; TUMOR NECROSIS FACTOR ALPHA; 1H (1,2,4)OXADIAZOLO(4,3 A)QUINOXALIN 1 ONE; 1H-(1,2,4)OXADIAZOLO(4,3-A)QUINOXALIN-1-ONE; CASP3 PROTEIN, RAT; CASPASE; CYTOKINE; DNA FRAGMENT; ENZYME INHIBITOR; IMIDAZOLE DERIVATIVE; OXADIAZOLE DERIVATIVE; PYRIDINE DERIVATIVE; QUINOXALINE DERIVATIVE; MITOGEN ACTIVATED PROTEIN KINASE P38; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ANTIAPOPTOTIC ACTIVITY; APOPTOSIS; ARTERY INJURY; CELL CULTURE; CELL CYCLE; CELL DEATH; CIRCULATION; CONFERENCE PAPER; CONTROLLED STUDY; DNA DAMAGE; DNA LADDERING; ENZYME ACTIVATION; NONHUMAN; RAT; SIGNAL TRANSDUCTION; VASCULAR SMOOTH MUSCLE; ANIMAL; ARTICLE; CYTOLOGY; DRUG EFFECT; METABOLISM; PHYSIOLOGY; SMOOTH MUSCLE FIBER; DNA FRAGMENTATION; DNA FRAGMENTATION ASSAY; DRUG EXPOSURE; HUMAN; VASCULAR SMOOTH MUSCLE CELL;

ANIMALIA;

ANIMALS; APOPTOSIS; CARBON MONOXIDE; CASPASE 3; CASPASES; CELLS, CULTURED; CYTOKINES; DNA FRAGMENTATION; ENZYME INHIBITORS; IMIDAZOLES; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; OXADIAZOLES; PYRIDINES; QUINOXALINES; RATS;

EID: 0037530508     PISSN: 15353702     EISSN: None     Source Type: Journal    
DOI: 10.1177/15353702-0322805-30     Document Type: Conference Paper

References (26)

1. Tenhunen R, Marver HS, Schmidt R. The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase. Proc Natl Acad Sci USA 244:6388-6394, 1968.
2. Durante W, Schafer AI. Carbon monoxide and vascular cell function. Int J Mol Med 2:255-262, 1998.
3. Zhang F, Kaide J-I, Rodriguez-Mulero F, Abraham NG, Nasjletti A. Vasoregulatory function of the heme-heme oxygenase-carbon monoxide system. Am J Hypertens 14:62S-67S, 2001.
4. Wagner CT, Durante W, Christodoulides N, Hellums JD, Schafer AI. Hemodynamic forces induce the expression of heme oxygenase in cultured vascular smooth muscle cells. J Clin Inves 100:589-596, 1997.
5. Morita T, Mitsialis SA, Hoike H, Liu Y, Kourembanas S. Carbon monoxide controls the proliferation of hypoxic smooth muscle cells. J Biol Chem 272:32804-32809, 1997.
6. Peyton KJ, Reyna SV, Chapman GB, Ensenat D, Liu X, Wang H, Schafer AI, Durante W. Heme oxygenase-1-derived carbon monoxide is an autocrine inhibitor of vascular smooth muscle cell growth. Blood 99:4443-4448, 2002.
7. Morita T, Kourembanas S. Endothelial cell expression of vasoconstrictors and growth factors is regulated by smooth muscle cell-derived carbon monoxide. J Clin Invest 96:2676-2682, 1995.
8. Geng Y, Libby P. Evidence for apoptosis in advanced human atheroma: Colocalization with interleukin-1β converting enzyme. Am J Pathol 147:251-256, 1995.
9. Isner JM, Kearney M, Bortman S, Passeri J. Apoptosis in human atherosclerosis and restenosis. Circulation 91:2703-2711, 1995.
10. Sharifi AM, Schriffen EL. Apoptosis in vasculature of spontaneously hypertensive rats: Effect on angiotensin converting enzyme inhibitor and a calcium channel antagonist. Am J Hypertens 11:1108-1116, 1998.
11. Durante W, Schini VB, Catovsky S, Kroll MH, Vanhoutte PM, Schafer AI. Plasmin potentiates the induction of nitric oxide synthase by interleukin-1β in vascular smooth muscle. Am J Physiol Heart Circ Physiol 264:H617-H623, 1993.
12. Liu X, Chapman GB, Wang H, Durante W. Adenovirus-mediated heme oxygenase-1 gene expression stimulates apoptosis in vascular smooth muscle cells. Circulation 105:79-84, 2002.
13. Otterbein LE, Bach FH, Alam J, Soares M, Tao Lu H, Wysk M, Davis RJ, Flavell RA, Choi AM. Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway. Nat Med 6:422-428, 2000.
14. Morita T, Perella MA, Lee ME, Kourembanas S. Smooth muscle cell-derived carbon monoxide is a regulator of vascular cGMP. Proc Natl Acad Sci USA 92:1475-1479, 1995.
15. Christodoulides N, Durante W, Kroll MH, Schafer AI. Vascular smooth muscle cell heme oxygenases generate guanylyl cyclase-stimulatory carbon monoxide. Circulation 91:2306-2309, 1995.
16. Garthwaite J, Southam E, Boulton CL, Nielson EB, Schmidt K, Mayer B. Potent and selective inhibition of nitric oxide-sensitive guanylyl cyclase by 1H-[1,2,4]oxadiazolo[4,3-α]quinoxalin-1-one. Mol Pharmacol 48:184-188, 1995.
17. Brouard S, Otterbein LE, Anrather J, Tobiasch E, Bach F, Choi AMK, Soares MP. Carbon monoxide generated by heme oxygenase 1 suppresses endothelial cell apoptosis. J Exp Med 192:1015-1025, 2000.
18. Petrache I, Otterbein LE, Alam J, Wiegand GW, Choi AMK. Heme oxygenase-1 inhibits TNF-α-induced apoptosis in cultured fibroblasts. Am J Physiol Lung Cell Mol Physiol 278:L312-L319, 2000.
19. Turcanu V, Dhouib M, Gendrault JL, Poindron P. Carbon monoxide induces murine thymocyte apoptosis by a free radical-mediated mechanism. Cell Biol Toxicol 14:47-54, 1998.
20. Thom SR, Fisher D, Xu YA, Notarfrancesco K, Ischiropoulos H. Adaptive responses and apoptosis in endothelial cells exposed to carbon monoxide. Proc Natl Acad Sci USA 97:1305-1310, 2000.
21. Mallat Z, Tedgui A. Apoptosis in the vasculature: Mechanisms and functional importance. Br J Pharmacol 130:947-962, 2000.
22. Flynn PD, Byrne CD, Baglin TP, Weissberg PL, Bennett MR. Thrombin generation by apoptotic vascular smooth muscle cells. Blood 89:4378-4384, 1997.
23. Juan S-H, Lee T-S, Tseng K-W, Liou J-Y, Shyue S-K, Wu KK, Chau L-Y. Adenovirus-mediated heme oxygenase-1 gene transfer inhibits the development of atherosclerosis in apolipoprotein E-deficient mice. Circulation 104:1519-1525, 2001.
24. Ishikawa K, Sugawara D, Wang X, Suzuki K, Itabe H, Maruyama Y, Lusis AJ. Heme oxygenase-1 inhibits atherosclerotic lesion formation in LDL-receptor knockout mice. Circ Res 88:506-512, 2001.
25. Yet SF, Perella MA, Layne MD, Hsieh CM, Maemura K, Kobzik L, Wiesel P, Christou H, Kourembanas S, Lee ME. Hypoxia induces severe right ventricular dilatation and infarction in heme oxygenase-1 null mice. J Clin Invest 103:R23-R29, 1999.
26. Fujita T, Toda K, Karimova, Yan S-F, Naka Y, Yet S-F, Pinsky DJ. Paradoxical rescue from ischemic lung injury by inhaled carbon monoxide driven by derepression of fibrinolysis. Nat Med 7:598-604, 2001.