-
1
-
-
0347093672
-
Expression of BRI, the normal precursor of the amyloid protein of familial British dementia, in human brain
-
Akiyama H., Kondo H., Arai T., Ikeda K., Kato M., Iseki E., Schwab C., McGeer P.L. Expression of BRI, the normal precursor of the amyloid protein of familial British dementia, in human brain. Acta Neuropathol. (Berl) 2004, 107:53-58.
-
(2004)
Acta Neuropathol. (Berl)
, vol.107
, pp. 53-58
-
-
Akiyama, H.1
Kondo, H.2
Arai, T.3
Ikeda, K.4
Kato, M.5
Iseki, E.6
Schwab, C.7
McGeer, P.L.8
-
2
-
-
0035816661
-
A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60
-
Cao X., Sudhof T.C. A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60. Science 2001, 293:115-120.
-
(2001)
Science
, vol.293
, pp. 115-120
-
-
Cao, X.1
Sudhof, T.C.2
-
3
-
-
1442265701
-
Axonal transport of British and Danish amyloid peptides via secretory vesicles
-
Choi S.I., Vidal R., Frangione B., Levy E. Axonal transport of British and Danish amyloid peptides via secretory vesicles. FASEB J. 2004, 18:373-375.
-
(2004)
FASEB J.
, vol.18
, pp. 373-375
-
-
Choi, S.I.1
Vidal, R.2
Frangione, B.3
Levy, E.4
-
4
-
-
38349107593
-
The Alzheimer's disease beta-secretase enzyme, BACE1
-
Cole S.L., Vassar R. The Alzheimer's disease beta-secretase enzyme, BACE1. Mol. Neurodegener. 2007, 2:22.
-
(2007)
Mol. Neurodegener.
, vol.2
, pp. 22
-
-
Cole, S.L.1
Vassar, R.2
-
5
-
-
0037431082
-
Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-secretase complex
-
De Strooper B. Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-secretase complex. Neuron 2003, 38:9-12.
-
(2003)
Neuron
, vol.38
, pp. 9-12
-
-
De Strooper, B.1
-
6
-
-
0029742884
-
Isolation of markers for chondro-osteogenic differentiation using cDNA library subtraction. Molecular cloning and characterization of a gene belonging to a novel multigene family of integral membrane proteins
-
Deleersnijder W., Hong G., Cortvrindt R., Poirier C., Tylzanowski P., Pittois K., Van Marck E., Merregaert J. Isolation of markers for chondro-osteogenic differentiation using cDNA library subtraction. Molecular cloning and characterization of a gene belonging to a novel multigene family of integral membrane proteins. J. Biol. Chem. 1996, 271:19475-19482.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 19475-19482
-
-
Deleersnijder, W.1
Hong, G.2
Cortvrindt, R.3
Poirier, C.4
Tylzanowski, P.5
Pittois, K.6
Van Marck, E.7
Merregaert, J.8
-
7
-
-
0037421206
-
Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts
-
Ehehalt R., Keller P., Haass C., Thiele C., Simons K. Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts. J. Cell Biol. 2003, 160:113-123.
-
(2003)
J. Cell Biol.
, vol.160
, pp. 113-123
-
-
Ehehalt, R.1
Keller, P.2
Haass, C.3
Thiele, C.4
Simons, K.5
-
8
-
-
0033639083
-
Reinsertion or degradation of AMPA receptors determined by activity-dependent endocytic sorting
-
Ehlers M.D. Reinsertion or degradation of AMPA receptors determined by activity-dependent endocytic sorting. Neuron 2000, 28:511-525.
-
(2000)
Neuron
, vol.28
, pp. 511-525
-
-
Ehlers, M.D.1
-
9
-
-
24744440136
-
BRI2 interacts with amyloid precursor protein (APP) and regulates amyloid beta (Abeta) production
-
Fotinopoulou A., Tsachaki M., Vlavaki M., Poulopoulos A., Rostagno A., Frangione B., Ghiso J., Efthimiopoulos S. BRI2 interacts with amyloid precursor protein (APP) and regulates amyloid beta (Abeta) production. J. Biol. Chem. 2005, 280:30768-30772.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 30768-30772
-
-
Fotinopoulou, A.1
Tsachaki, M.2
Vlavaki, M.3
Poulopoulos, A.4
Rostagno, A.5
Frangione, B.6
Ghiso, J.7
Efthimiopoulos, S.8
-
10
-
-
34547670388
-
ApoER2 expression increases Abeta production while decreasing Amyloid Precursor Protein (APP) endocytosis: possible role in the partitioning of APP into lipid rafts and in the regulation of gamma-secretase activity
-
Fuentealba R.A., Barria M.I., Lee J., Cam J., Araya C., Escudero C.A., Inestrosa N.C., Bronfman F.C., Bu G., Marzolo M.P. ApoER2 expression increases Abeta production while decreasing Amyloid Precursor Protein (APP) endocytosis: possible role in the partitioning of APP into lipid rafts and in the regulation of gamma-secretase activity. Mol. Neurodegener. 2007, 2:14.
-
(2007)
Mol. Neurodegener.
, vol.2
, pp. 14
-
-
Fuentealba, R.A.1
Barria, M.I.2
Lee, J.3
Cam, J.4
Araya, C.5
Escudero, C.A.6
Inestrosa, N.C.7
Bronfman, F.C.8
Bu, G.9
Marzolo, M.P.10
-
11
-
-
52049112089
-
Evidence that the Amyloid beta Precursor Protein-intracellular domain lowers the stress threshold of neurons and has a "regulated" transcriptional role
-
Giliberto L., Zhou D., Weldon R., Tamagno E., De Luca P., Tabaton M., D'Adamio L. Evidence that the Amyloid beta Precursor Protein-intracellular domain lowers the stress threshold of neurons and has a "regulated" transcriptional role. Mol. Neurodegener. 2008, 3:12.
-
(2008)
Mol. Neurodegener.
, vol.3
, pp. 12
-
-
Giliberto, L.1
Zhou, D.2
Weldon, R.3
Tamagno, E.4
De Luca, P.5
Tabaton, M.6
D'Adamio, L.7
-
12
-
-
33847662852
-
Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide
-
Haass C., Selkoe D.J. Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide. Nat. Rev. Mol. Cell. Biol. 2007, 8:101-112.
-
(2007)
Nat. Rev. Mol. Cell. Biol.
, vol.8
, pp. 101-112
-
-
Haass, C.1
Selkoe, D.J.2
-
13
-
-
84880187014
-
Alzheimer's disease: the amyloid cascade hypothesis: an update and reappraisal
-
Hardy J. Alzheimer's disease: the amyloid cascade hypothesis: an update and reappraisal. J. Alzheimers Dis. 2006, 9:151-153.
-
(2006)
J. Alzheimers Dis.
, vol.9
, pp. 151-153
-
-
Hardy, J.1
-
14
-
-
33644862462
-
Amyloid precursor protein and Notch intracellular domains are generated after transport of their precursors to the cell surface
-
Kaether C., Schmitt S., Willem M., Haass C. Amyloid precursor protein and Notch intracellular domains are generated after transport of their precursors to the cell surface. Traffic 2006, 7:408-415.
-
(2006)
Traffic
, vol.7
, pp. 408-415
-
-
Kaether, C.1
Schmitt, S.2
Willem, M.3
Haass, C.4
-
15
-
-
44949217679
-
BRI2 (ITM2b) inhibits Abeta deposition in vivo
-
Kim J., Miller V.M., Levites Y., West K.J., Zwizinski C.W., Moore B.D., Troendle F.J., Bann M., Verbeeck C., Price R.W., Smithson L., Sonoda L., Wagg K., Rangachari V., Zou F., Younkin S.G., Graff-Radford N., Dickson D., Rosenberry T., Golde T.E. BRI2 (ITM2b) inhibits Abeta deposition in vivo. J. Neurosci. 2008, 28:6030-6036.
-
(2008)
J. Neurosci.
, vol.28
, pp. 6030-6036
-
-
Kim, J.1
Miller, V.M.2
Levites, Y.3
West, K.J.4
Zwizinski, C.W.5
Moore, B.D.6
Troendle, F.J.7
Bann, M.8
Verbeeck, C.9
Price, R.W.10
Smithson, L.11
Sonoda, L.12
Wagg, K.13
Rangachari, V.14
Zou, F.15
Younkin, S.G.16
Graff-Radford, N.17
Dickson, D.18
Rosenberry, T.19
Golde, T.E.20
more..
-
16
-
-
0033352083
-
Furin mediates enhanced production of fibrillogenic ABri peptides in familial British dementia
-
Kim S.H., Wang R., Gordon D.J., Bass J., Steiner D.F., Lynn D.G., Thinakaran G., Meredith S.C., Sisodia S.S. Furin mediates enhanced production of fibrillogenic ABri peptides in familial British dementia. Nat. Neurosci. 1999, 2:984-988.
-
(1999)
Nat. Neurosci.
, vol.2
, pp. 984-988
-
-
Kim, S.H.1
Wang, R.2
Gordon, D.J.3
Bass, J.4
Steiner, D.F.5
Lynn, D.G.6
Thinakaran, G.7
Meredith, S.C.8
Sisodia, S.S.9
-
17
-
-
0034725615
-
Regulation of X11L-dependent amyloid precursor protein metabolism by XB51, a novel X11L-binding protein
-
Lee D.S., Tomita S., Kirino Y., Suzuki T. Regulation of X11L-dependent amyloid precursor protein metabolism by XB51, a novel X11L-binding protein. J. Biol. Chem. 2000, 275:23134-23138.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 23134-23138
-
-
Lee, D.S.1
Tomita, S.2
Kirino, Y.3
Suzuki, T.4
-
18
-
-
0037007140
-
A physiologic signaling role for the gamma-secretase-derived intracellular fragment of APP
-
Leissring M.A., Murphy M.P., Mead T.R., Akbari Y., Sugarman M.C., Jannatipour M., Anliker B., Muller U., Saftig P., De Strooper B., Wolfe M.S., Golde T.E., LaFerla F.M. A physiologic signaling role for the gamma-secretase-derived intracellular fragment of APP. Proc. Natl. Acad. Sci. U.S.A 2002, 99:4697-4702.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A
, vol.99
, pp. 4697-4702
-
-
Leissring, M.A.1
Murphy, M.P.2
Mead, T.R.3
Akbari, Y.4
Sugarman, M.C.5
Jannatipour, M.6
Anliker, B.7
Muller, U.8
Saftig, P.9
De Strooper, B.10
Wolfe, M.S.11
Golde, T.E.12
LaFerla, F.M.13
-
19
-
-
17644419726
-
Genetic and molecular aspects of Alzheimer's disease shed light on new mechanisms of transcriptional regulation
-
Marambaud P., Robakis N.K. Genetic and molecular aspects of Alzheimer's disease shed light on new mechanisms of transcriptional regulation. Genes Brain Behav. 2005, 4:134-146.
-
(2005)
Genes Brain Behav.
, vol.4
, pp. 134-146
-
-
Marambaud, P.1
Robakis, N.K.2
-
20
-
-
23844491144
-
The familial dementia BRI2 gene binds the Alzheimer gene amyloid-beta precursor protein and inhibits amyloid-beta production
-
Matsuda S., Giliberto L., Matsuda Y., Davies P., McGowan E., Pickford F., Ghiso J., Frangione B., D'Adamio L. The familial dementia BRI2 gene binds the Alzheimer gene amyloid-beta precursor protein and inhibits amyloid-beta production. J. Biol. Chem. 2005, 280:28912-28916.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 28912-28916
-
-
Matsuda, S.1
Giliberto, L.2
Matsuda, Y.3
Davies, P.4
McGowan, E.5
Pickford, F.6
Ghiso, J.7
Frangione, B.8
D'Adamio, L.9
-
21
-
-
52049089901
-
BRI2 inhibits amyloid beta-peptide precursor protein processing by interfering with the docking of secretases to the substrate
-
Matsuda S., Giliberto L., Matsuda Y., McGowan E.M., D'Adamio L. BRI2 inhibits amyloid beta-peptide precursor protein processing by interfering with the docking of secretases to the substrate. J. Neurosci. 2008, 28:8668-8676.
-
(2008)
J. Neurosci.
, vol.28
, pp. 8668-8676
-
-
Matsuda, S.1
Giliberto, L.2
Matsuda, Y.3
McGowan, E.M.4
D'Adamio, L.5
-
22
-
-
67650156458
-
BRI3 inhibits APP processing in a mechanistically distinct manner than its homologue dementia gene BRI2
-
Matsuda S., Matsuda Y., D'Adamio L. BRI3 inhibits APP processing in a mechanistically distinct manner than its homologue dementia gene BRI2. J. Biol. Chem. 2009, 284:15815-15825.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 15815-15825
-
-
Matsuda, S.1
Matsuda, Y.2
D'Adamio, L.3
-
23
-
-
0034488295
-
Generation of an apoptotic intracellular peptide by gamma-secretase cleavage of Alzheimer's amyloid beta protein precursor
-
Passer B., Pellegrini L., Russo C., Siegel R.M., Lenardo M.J., Schettini G., Bachmann M., Tabaton M., D'Adamio L. Generation of an apoptotic intracellular peptide by gamma-secretase cleavage of Alzheimer's amyloid beta protein precursor. J. Alzheimers Dis. 2000, 2:289-301.
-
(2000)
J. Alzheimers Dis.
, vol.2
, pp. 289-301
-
-
Passer, B.1
Pellegrini, L.2
Russo, C.3
Siegel, R.M.4
Lenardo, M.J.5
Schettini, G.6
Bachmann, M.7
Tabaton, M.8
D'Adamio, L.9
-
24
-
-
0041355557
-
Notch and Presenilin: regulated intramembrane proteolysis links development and degeneration
-
Selkoe D., Kopan R. Notch and Presenilin: regulated intramembrane proteolysis links development and degeneration. Annu. Rev. Neurosci. 2003, 26:565-597.
-
(2003)
Annu. Rev. Neurosci.
, vol.26
, pp. 565-597
-
-
Selkoe, D.1
Kopan, R.2
-
26
-
-
49149124343
-
Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
-
Shankar G.M., Li S., Mehta T.H., Garcia-Munoz A., Shepardson N.E., Smith I., Brett F.M., Farrell M.A., Rowan M.J., Lemere C.A., Regan C.M., Walsh D.M., Sabatini B.L., Selkoe D.J. Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory. Nat. Med. 2008, 14:837-842.
-
(2008)
Nat. Med.
, vol.14
, pp. 837-842
-
-
Shankar, G.M.1
Li, S.2
Mehta, T.H.3
Garcia-Munoz, A.4
Shepardson, N.E.5
Smith, I.6
Brett, F.M.7
Farrell, M.A.8
Rowan, M.J.9
Lemere, C.A.10
Regan, C.M.11
Walsh, D.M.12
Sabatini, B.L.13
Selkoe, D.J.14
-
27
-
-
0036548070
-
Gamma-secretase, Notch, Abeta and Alzheimer's disease: where do the presenilins fit in?
-
Sisodia S.S., St George-Hyslop P.H. Gamma-secretase, Notch, Abeta and Alzheimer's disease: where do the presenilins fit in?. Nat. Rev. Neurosci. 2002, 3:281-290.
-
(2002)
Nat. Rev. Neurosci.
, vol.3
, pp. 281-290
-
-
Sisodia, S.S.1
St George-Hyslop, P.H.2
-
28
-
-
56349119351
-
Linking Abeta and tau in late-onset Alzheimer's disease: a dual pathway hypothesis
-
Small S.A., Duff K. Linking Abeta and tau in late-onset Alzheimer's disease: a dual pathway hypothesis. Neuron 2008, 60:534-542.
-
(2008)
Neuron
, vol.60
, pp. 534-542
-
-
Small, S.A.1
Duff, K.2
-
29
-
-
13844255273
-
Molecular biology and genetics of Alzheimer's disease
-
St George-Hyslop P.H., Petit A. Molecular biology and genetics of Alzheimer's disease. C. R. Biol. 2005, 328:119-130.
-
(2005)
C. R. Biol.
, vol.328
, pp. 119-130
-
-
St George-Hyslop, P.H.1
Petit, A.2
-
30
-
-
0032513060
-
Cleavage of Alzheimer's amyloid precursor protein (APP) by secretases occurs after O-glycosylation of APP in the protein secretory pathway. Identification of intracellular compartments in which APP cleavage occurs without using toxic agents that interfere with protein metabolism
-
Tomita S., Kirino Y., Suzuki T. Cleavage of Alzheimer's amyloid precursor protein (APP) by secretases occurs after O-glycosylation of APP in the protein secretory pathway. Identification of intracellular compartments in which APP cleavage occurs without using toxic agents that interfere with protein metabolism. J. Biol. Chem. 1998, 273:6277-6284.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 6277-6284
-
-
Tomita, S.1
Kirino, Y.2
Suzuki, T.3
-
31
-
-
34247887500
-
Dual roles of the transmembrane protein p23/TMP21 in the modulation of amyloid precursor protein metabolism
-
Vetrivel K.S., Gong P., Bowen J.W., Cheng H., Chen Y., Carter M., Nguyen P.D., Placanica L., Wieland F.T., Li Y.M., Kounnas M.Z., Thinakaran G. Dual roles of the transmembrane protein p23/TMP21 in the modulation of amyloid precursor protein metabolism. Mol. Neurodegener. 2007, 2:4.
-
(2007)
Mol. Neurodegener.
, vol.2
, pp. 4
-
-
Vetrivel, K.S.1
Gong, P.2
Bowen, J.W.3
Cheng, H.4
Chen, Y.5
Carter, M.6
Nguyen, P.D.7
Placanica, L.8
Wieland, F.T.9
Li, Y.M.10
Kounnas, M.Z.11
Thinakaran, G.12
-
32
-
-
0035925577
-
Sequence, genomic structure and tissue expression of human BRI3, a member of the BRI gene family
-
Vidal R., Calero M., Revesz T., Plant G., Ghiso J., Frangione B. Sequence, genomic structure and tissue expression of human BRI3, a member of the BRI gene family. Gene 2001, 266:95-102.
-
(2001)
Gene
, vol.266
, pp. 95-102
-
-
Vidal, R.1
Calero, M.2
Revesz, T.3
Plant, G.4
Ghiso, J.5
Frangione, B.6
-
33
-
-
0033600228
-
A stop-codon mutation in the BRI gene associated with familial British dementia
-
Vidal R., Frangione B., Rostagno A., Mead S., Revesz T., Plant G., Ghiso J. A stop-codon mutation in the BRI gene associated with familial British dementia. Nature 1999, 399:776-781.
-
(1999)
Nature
, vol.399
, pp. 776-781
-
-
Vidal, R.1
Frangione, B.2
Rostagno, A.3
Mead, S.4
Revesz, T.5
Plant, G.6
Ghiso, J.7
-
34
-
-
0034712749
-
A decamer duplication in the 3′ region of the BRI gene originates an amyloid peptide that is associated with dementia in a Danish kindred
-
Vidal R., Revesz T., Rostagno A., Kim E., Holton J.L., Bek T., Bojsen-Moller M., Braendgaard H., Plant G., Ghiso J., Frangione B. A decamer duplication in the 3′ region of the BRI gene originates an amyloid peptide that is associated with dementia in a Danish kindred. Proc. Natl. Acad. Sci. U.S.A. 2000, 97:4920-4925.
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 4920-4925
-
-
Vidal, R.1
Revesz, T.2
Rostagno, A.3
Kim, E.4
Holton, J.L.5
Bek, T.6
Bojsen-Moller, M.7
Braendgaard, H.8
Plant, G.9
Ghiso, J.10
Frangione, B.11
-
35
-
-
13244285027
-
Beta-amyloid protein converting enzyme 1 and brain-specific type II membrane protein BRI3: binding partners processed by furin
-
Wickham L., Benjannet S., Marcinkiewicz E., Chretien M., Seidah N.G. Beta-amyloid protein converting enzyme 1 and brain-specific type II membrane protein BRI3: binding partners processed by furin. J. Neurochem. 2005, 92:93-102.
-
(2005)
J. Neurochem.
, vol.92
, pp. 93-102
-
-
Wickham, L.1
Benjannet, S.2
Marcinkiewicz, E.3
Chretien, M.4
Seidah, N.G.5
-
36
-
-
5344240284
-
Amyloid-beta precursor protein processing in neurodegeneration
-
Wilquet V., De Strooper B. Amyloid-beta precursor protein processing in neurodegeneration. Curr Opin. Neurobiol. 2004, 14:582-588.
-
(2004)
Curr Opin. Neurobiol.
, vol.14
, pp. 582-588
-
-
Wilquet, V.1
De Strooper, B.2
-
37
-
-
33947242870
-
When loss is gain: reduced presenilin proteolytic function leads to increased Abeta42/Abeta40. Talking Point on the role of presenilin mutations in Alzheimer disease
-
Wolfe M.S. When loss is gain: reduced presenilin proteolytic function leads to increased Abeta42/Abeta40. Talking Point on the role of presenilin mutations in Alzheimer disease. EMBO Rep. 2007, 8:136-140.
-
(2007)
EMBO Rep.
, vol.8
, pp. 136-140
-
-
Wolfe, M.S.1
|