BRI3 inhibits amyloid precursor protein processing in a mechanistically distinct manner from its homologue Dementia gene BRI2

Journal of Biological Chemistry

Volumn 284, Issue 23, 2009, Pages 15816-15825

  Matsuda, Shuji ^a   Matsuda, Yukiko ^a   D'Adamio, Luciano ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; AMYLOID PRECURSOR PROTEINS; C-TERMINAL FRAGMENTS; COMPETITIVE INHIBITION; DANISH DEMENTIA; GENE FAMILIES; MOUSE BRAIN; N2A CELLS; NEGATIVE REGULATORS; NEW APPROACHES; OVER-EXPRESSION; PROTEOLYTIC PROCESSING; RNA INTERFERENCE; SECRETASE; SECRETASES; SENILE PLAQUES;

AMINES; GLYCOPROTEINS; NUCLEIC ACIDS; RNA; SULFUR COMPOUNDS;

PUMPING PLANTS;

ALPHA SECRETASE; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; MEMBRANE PROTEIN; PROTEIN BRI2; PROTEIN BRI3; UNCLASSIFIED DRUG; AMYLOID; APLP2 PROTEIN, HUMAN; BRI3 PROTEIN, HUMAN; ITM2B PROTEIN, HUMAN; ITM2B PROTEIN, MOUSE; NERVE PROTEIN; PRIMER DNA;

ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; ENZYME RELEASE; EXTRACELLULAR SPACE; GENE OVEREXPRESSION; GENE SEQUENCE; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; RNA INTERFERENCE; SEQUENCE ALIGNMENT; ALZHEIMER DISEASE; ANIMAL; CELL LINE; DEMENTIA; DRUG ANTAGONISM; GENETIC TRANSFECTION; GENETICS; HELA CELL; KIDNEY; METABOLISM; MIDDLE AGED; MOLECULAR CLONING; MUTATION; PROTEIN BINDING; STOP CODON;

ALZHEIMER DISEASE; AMYLOID; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CELL LINE; CLONING, MOLECULAR; CODON, TERMINATOR; DEMENTIA; DNA PRIMERS; HELA CELLS; HUMANS; KIDNEY; MEMBRANE PROTEINS; MICE; MIDDLE AGED; MUTATION; NERVE TISSUE PROTEINS; PROTEIN BINDING; TRANSFECTION;

EID: 67650156458     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.006403     Document Type: Article

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