Copper(II)-induced secondary structure changes and reduced folding stability of the prion protein

Journal of Molecular Biology

Volumn 410, Issue 3, 2011, Pages 369-382

  Younan, Nadine D ^a   Klewpatinond, Mark ^a   Davies, Paul ^b   Ruban, Alexander V ^a   Brown, David R ^b   Viles, John H ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b University of Bath   (United Kingdom)

Author keywords

circular dichroism; PrP; unfolding; urea

Indexed keywords

CUPRIC ION; PRION PROTEIN; RECOMBINANT PROTEIN; UREA;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CIRCULAR DICHROISM; INFRARED SPECTROSCOPY; MOUSE; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN PROCESSING; PROTEIN PURIFICATION; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; THERMODYNAMICS;

EID: 79959514608     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2011.05.013     Document Type: Article

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