Influence of amino acid substitutions related to inherited human prion diseases on the thermodynamic stability of the cellular prion protein

Biochemistry

Volumn 38, Issue 11, 1999, Pages 3258-3267

  Liemann, Susanne ^a,b   Glockshuber, Rudi ^a  

^a ETH ZURICH   (Switzerland)

^b BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PRION PROTEIN;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BRAIN SPONGIOSIS; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; COVALENT BOND; GENE INSERTION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRION DISEASE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROCESSING; PROTEIN STABILITY; SCRAPIE; THERMODYNAMICS;

AMINO ACID SUBSTITUTION; ANIMALS; CIRCULAR DICHROISM; HUMANS; INCLUSION BODIES; MICE; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PEPTIDE FRAGMENTS; PERIPLASM; PRION DISEASES; PRIONS; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PRPC PROTEINS; SOLUBILITY; THERMODYNAMICS; VARIATION (GENETICS);

EID: 0033574161     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi982714g     Document Type: Article

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