Cu(II) induces small-size aggregates with amyloid characteristics in two alleles of recombinant ovine prion proteins

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1764, Issue 7, 2006, Pages 1218-1226

  Tsiroulnikov, Kirill ^a,c   Rezaei, Human ^b   Dalgalarrondo, Michèle ^a   Chobert, Jean Marc ^a   Grosclaude, Jeanne ^b   Haertlé, Thomas ^a  

^a INRA   (France)

^b INRA Institut National de la Recherche Agronomique   (France)

^c SHEMYAKIN OVCHINNIKOV INSTITUTE OF BIOORGANIC CHEMISTRY   (Russian Federation)

Author keywords

Amyloid; Copper; Hydrolysis; Metal ions; Prion protein; Zinc

Indexed keywords

AMYLOID; CUPRIC ION; METAL CHELATE; PRION PROTEIN; THIOFLAVINE;

ALLELE; ALPHA HELIX; ARTICLE; BETA SHEET; HYPOTHESIS; INFECTION RESISTANCE; OLIGOMERIZATION; PARTICLE SIZE; PHASE TRANSITION; PHYSICAL CHEMISTRY; PRION DISEASE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; SCRAPIE; SHEEP;

ALLELES; AMYLOID; ANIMALS; CATIONS, DIVALENT; CIRCULAR DICHROISM; COPPER; ENDOPEPTIDASE K; HEAT; HYDROLYSIS; LIGHT; PARTICLE SIZE; PEPTIDE FRAGMENTS; POLYMORPHISM, GENETIC; PROTEIN DENATURATION; PROTEIN STRUCTURE, SECONDARY; PRPC PROTEINS; RECOMBINANT PROTEINS; SCATTERING, RADIATION; SHEEP; SODIUM CHLORIDE; SPECTROMETRY, FLUORESCENCE; THIAZOLES; ZINC;

OVIS; OVIS ARIES;

EID: 33746034888     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbapap.2006.04.013     Document Type: Article

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