-
1
-
-
34248160486
-
Toxic human islet amyloid polypeptide (h- IAPP) oligomers are intracellular, and vaccination to induce antitoxic oligomer antibodies does not prevent h-IAPP-induced betacell apoptosis in h-IAPP transgenic mice
-
Lin, C.Y.; Gurlo, T.; Kayed, R.; Butler, A.E.; Haataja, L.; Glabe, C.G.; Butler, P.C., Toxic human islet amyloid polypeptide (h- IAPP) oligomers are intracellular, and vaccination to induce antitoxic oligomer antibodies does not prevent h-IAPP-induced betacell apoptosis in h-IAPP transgenic mice. Diabetes, 2007, 56 (5), 1324-32.
-
(2007)
Diabetes
, vol.56
, Issue.5
, pp. 1324-1332
-
-
Lin, C.Y.1
Gurlo, T.2
Kayed, R.3
Butler, A.E.4
Haataja, L.5
Glabe, C.G.6
Butler, P.C.7
-
2
-
-
49149098525
-
Tau aggregates: Toxic, inert, or protective species?
-
Bretteville, A.; Planel, E., Tau aggregates: toxic, inert, or protective species? J. Alzheimers Dis., 2008, 14 (4), 431-6.
-
(2008)
J. Alzheimers Dis.
, vol.14
, Issue.4
, pp. 431-436
-
-
Bretteville, A.1
Planel, E.2
-
3
-
-
0037022186
-
Heparin and other glycosaminoglycans stimulate the formation of amyloid fibrils from alpha-synuclein in vitro
-
Cohlberg, J.A.; Li, J.; Uversky, V.N.; Fink, A.L., Heparin and other glycosaminoglycans stimulate the formation of amyloid fibrils from alpha-synuclein in vitro. Biochemistry, 2002, 41 (5), 1502-11.
-
(2002)
Biochemistry
, vol.41
, Issue.5
, pp. 1502-1511
-
-
Cohlberg, J.A.1
Li, J.2
Uversky, V.N.3
Fink, A.L.4
-
4
-
-
0035997236
-
Glycosaminoglycans and beta-amyloid, prion and tau peptides in neurodegenerative diseases
-
Diaz-Nido, J.; Wandosell, F.; Avila, J., Glycosaminoglycans and beta-amyloid, prion and tau peptides in neurodegenerative diseases. Peptides, 2002, 23 (7), 1323-32.
-
(2002)
Peptides
, vol.23
, Issue.7
, pp. 1323-1332
-
-
Diaz-Nido, J.1
Wandosell, F.2
Avila, J.3
-
5
-
-
56649100319
-
The structure of glycosaminoglycans and their interactions with proteins
-
Gandhi, N.S.; Mancera, R.L., The structure of glycosaminoglycans and their interactions with proteins. Chem. Biol. Drug Des., 2008, 72 (6), 455-82.
-
(2008)
Chem. Biol. Drug Des.
, vol.72
, Issue.6
, pp. 455-482
-
-
Gandhi, N.S.1
Mancera, R.L.2
-
6
-
-
70350371594
-
Kinetic analysis of amyloid formation in the presence of heparan sulfate: Faster unfolding and change of pathway
-
Motamedi-Shad, N.; Monsellier, E.; Torrassa, S.; Relini, A.; Chiti, F., Kinetic analysis of amyloid formation in the presence of heparan sulfate: faster unfolding and change of pathway. J. Biol. Chem., 2009, 284 (43), 29921-34.
-
(2009)
J. Biol. Chem.
, vol.284
, Issue.43
, pp. 29921-29934
-
-
Motamedi-Shad, N.1
Monsellier, E.2
Torrassa, S.3
Relini, A.4
Chiti, F.5
-
7
-
-
0028978227
-
Proteoglycan-mediated inhibition of A beta proteolysis. A potential cause of senile plaque accumulation
-
Gupta-Bansal, R.; Frederickson, R.C.; Brunden, K.R., Proteoglycan-mediated inhibition of A beta proteolysis. A potential cause of senile plaque accumulation. J. Biol. Chem., 1995, 270 (31), 18666-71.
-
(1995)
J. Biol. Chem.
, vol.270
, Issue.31
, pp. 18666-18671
-
-
Gupta-Bansal, R.1
Frederickson, R.C.2
Brunden, K.R.3
-
8
-
-
15744403559
-
Structural insights into biological roles of protein-glycosaminoglycan interactions
-
Raman, R.; Sasisekharan, V.; Sasisekharan, R., Structural insights into biological roles of protein-glycosaminoglycan interactions. Chem. Biol., 2005, 12 (3), 267-77.
-
(2005)
Chem. Biol.
, vol.12
, Issue.3
, pp. 267-277
-
-
Raman, R.1
Sasisekharan, V.2
Sasisekharan, R.3
-
9
-
-
35748985291
-
Glycosaminoglycans and proteoglycans: Overlooked entities?
-
Yung, S.; Chan, T.M., Glycosaminoglycans and proteoglycans: overlooked entities? Perit. Dial. Int., 2007, 27 Suppl 2, S104-9.
-
(2007)
Perit. Dial. Int.
, vol.27
, Issue.SUPPL. 2
, pp. 104-109
-
-
Yung, S.1
Chan, T.M.2
-
10
-
-
0033794318
-
Recent advances in the study of the biosynthesis and functions of sulfated glycosaminoglycans
-
Sugahara, K.; Kitagawa, H., Recent advances in the study of the biosynthesis and functions of sulfated glycosaminoglycans. Curr. Opin. Struct. Biol., 2000, 10 (5), 518-27.
-
(2000)
Curr. Opin. Struct. Biol.
, vol.10
, Issue.5
, pp. 518-527
-
-
Sugahara, K.1
Kitagawa, H.2
-
11
-
-
0036818793
-
Heparin and heparan sulfate biosynthesis
-
Sugahara, K.; Kitagawa, H., Heparin and heparan sulfate biosynthesis. IUBMB Life, 2002, 54 (4), 163-75.
-
(2002)
IUBMB Life
, vol.54
, Issue.4
, pp. 163-175
-
-
Sugahara, K.1
Kitagawa, H.2
-
12
-
-
12344310615
-
Functions of heparan sulfate proteoglycans in cell signaling during development
-
Lin, X., Functions of heparan sulfate proteoglycans in cell signaling during development. Development, 2004, 131 (24), 6009-21.
-
(2004)
Development
, vol.131
, Issue.24
, pp. 6009-6021
-
-
Lin, X.1
-
13
-
-
33745439311
-
The biological relevance of chemokineproteoglycan interactions
-
Proudfoot, A.E., The biological relevance of chemokineproteoglycan interactions. Biochem. Soc. Trans., 2006, 34 (Pt 3), 422-6.
-
(2006)
Biochem. Soc. Trans.
, vol.34
, Issue.PART 3
, pp. 422-426
-
-
Proudfoot, A.E.1
-
14
-
-
34447508446
-
Eotaxin selectively binds heparin. An interaction that protects eotaxin from proteolysis and potentiates chemotactic activity in vivo
-
Ellyard, J.I.; Simson, L.; Bezos, A.; Johnston, K.; Freeman, C.; Parish, C.R., Eotaxin selectively binds heparin. An interaction that protects eotaxin from proteolysis and potentiates chemotactic activity in vivo. J. Biol. Chem., 2007, 282 (20), 15238-47.
-
(2007)
J. Biol. Chem.
, vol.282
, Issue.20
, pp. 15238-15247
-
-
Ellyard, J.I.1
Simson, L.2
Bezos, A.3
Johnston, K.4
Freeman, C.5
Parish, C.R.6
-
15
-
-
6344284808
-
Heparan sulfate/heparin oligosaccharides protect stromal cell-derived factor-1 (SDF-1)/CXCL12 against proteolysis induced by CD26/dipeptidyl peptidase IV
-
Sadir, R.; Imberty, A.; Baleux, F.; Lortat-Jacob, H., Heparan sulfate/heparin oligosaccharides protect stromal cell-derived factor-1 (SDF-1)/CXCL12 against proteolysis induced by CD26/dipeptidyl peptidase IV. J. Biol. Chem., 2004, 279 (42), 43854-60.
-
(2004)
J. Biol. Chem.
, vol.279
, Issue.42
, pp. 43854-43860
-
-
Sadir, R.1
Imberty, A.2
Baleux, F.3
Lortat-Jacob, H.4
-
16
-
-
70149088868
-
Interactions between heparan sulfate and proteins-design and functional implications
-
Lindahl, U.; Li, J.P., Interactions between heparan sulfate and proteins-design and functional implications. Int. Rev. Cell Mol. Biol., 2009, 276, 105-59.
-
(2009)
Int. Rev. Cell Mol. Biol.
, vol.276
, pp. 105-159
-
-
Lindahl, U.1
Li, J.P.2
-
17
-
-
77956408223
-
Glycosaminoglycans as polyelectrolytes
-
Seyrek, E.; Dubin, P., Glycosaminoglycans as polyelectrolytes. Adv. Colloid Interface Sci., 2010, 158 (1-2), 119-29.
-
(2010)
Adv. Colloid Interface Sci.
, vol.158
, Issue.1-2
, pp. 119-129
-
-
Seyrek, E.1
Dubin, P.2
-
18
-
-
24644505197
-
Identification of common and specific growth factor binding sites in heparan sulfate proteoglycans
-
Chu, C.L.; Goerges, A.L.; Nugent, M.A., Identification of common and specific growth factor binding sites in heparan sulfate proteoglycans. Biochemistry, 2005, 44 (36), 12203-13.
-
(2005)
Biochemistry
, vol.44
, Issue.36
, pp. 12203-12213
-
-
Chu, C.L.1
Goerges, A.L.2
Nugent, M.A.3
-
19
-
-
2342447936
-
Intracellular proteoglycans
-
Kolset, S.O.; Prydz, K.; Pejler, G., Intracellular proteoglycans. Biochem. J., 2004, 379 (Pt 2), 217-27.
-
(2004)
Biochem. J.
, vol.379
, Issue.PART 2
, pp. 217-227
-
-
Kolset, S.O.1
Prydz, K.2
Pejler, G.3
-
20
-
-
0034146793
-
Biosynthesis of heparan sulfate and the tumor suppressor EXT gene family
-
Kitagawa, H.; Sugahara, K., [Biosynthesis of heparan sulfate and the tumor suppressor EXT gene family]. Tanpakushitsu Kakusan Koso, 2000, 45 (4), 579-86.
-
(2000)
Tanpakushitsu Kakusan Koso
, vol.45
, Issue.4
, pp. 579-586
-
-
Kitagawa, H.1
Sugahara, K.2
-
21
-
-
0033975514
-
Synthesis and sorting of proteoglycans
-
Prydz, K.; Dalen, K.T., Synthesis and sorting of proteoglycans. J. Cell Sci., 2000, 113 Pt 2, 193-205.
-
(2000)
J. Cell Sci.
, vol.113
, Issue.PART 2
, pp. 193-205
-
-
Prydz, K.1
Dalen, K.T.2
-
22
-
-
30744451472
-
Glycosaminoglycans and their proteoglycans: Host-associated molecular patterns for initiation and modulation of inflammation
-
Taylor, K.R.; Gallo, R.L., Glycosaminoglycans and their proteoglycans: host-associated molecular patterns for initiation and modulation of inflammation. FASEB J., 2006, 20 (1), 9-22.
-
(2006)
FASEB J
, vol.20
, Issue.1
, pp. 9-22
-
-
Taylor, K.R.1
Gallo, R.L.2
-
23
-
-
22344434913
-
Inflammatory pathology and the anti-inflammation of saccharide substances in Alzheimer's disease
-
Wang, S.H.; Li, J.; Geng, M.Y., [Inflammatory pathology and the anti-inflammation of saccharide substances in Alzheimer's disease]. Sheng Li Ke Xue Jin Zhan, 2005, 36 (1), 67-70.
-
(2005)
Sheng Li Ke Xue Jin Zhan
, vol.36
, Issue.1
, pp. 67-70
-
-
Wang, S.H.1
Li, J.2
Geng, M.Y.3
-
24
-
-
30744451472
-
Glycosaminoglycans and their proteoglycans: Host-associated molecular patterns for initiation and modulation of inflammation 10.1096/fj.05-4682rev
-
Taylor, K.R.; Gallo, R.L., Glycosaminoglycans and their proteoglycans: host-associated molecular patterns for initiation and modulation of inflammation 10.1096/fj.05-4682rev. FASEB J., 2006, 20 (1), 9-22.
-
(2006)
FASEB J
, vol.20
, Issue.1
, pp. 9-22
-
-
Taylor, K.R.1
Gallo, R.L.2
-
25
-
-
34548282181
-
The heparin/heparan sulfate sequence that interacts with cyclophilin B contains a 3-O-sulfated N-unsubstituted glucosamine residue
-
Vanpouille, C.; Deligny, A.; Delehedde, M.; Denys, A.; Melchior, A.; Lienard, X.; Lyon, M.; Mazurier, J.; Fernig, D.G.; Allain, F., The heparin/heparan sulfate sequence that interacts with cyclophilin B contains a 3-O-sulfated N-unsubstituted glucosamine residue. J. Biol. Chem., 2007, 282 (33), 24416-29.
-
(2007)
J. Biol. Chem.
, vol.282
, Issue.33
, pp. 24416-24429
-
-
Vanpouille, C.1
Deligny, A.2
Delehedde, M.3
Denys, A.4
Melchior, A.5
Lienard, X.6
Lyon, M.7
Mazurier, J.8
Fernig, D.G.9
Allain, F.10
-
26
-
-
70349661239
-
Heparan sulfate promotes the aggregation of HDL-associated serum amyloid A: Evidence for a proamyloidogenic histidine molecular switch
-
Elimova, E.; Kisilevsky, R.; Ancsin, J.B., Heparan sulfate promotes the aggregation of HDL-associated serum amyloid A: evidence for a proamyloidogenic histidine molecular switch. FASEB J., 2009, 23 (10), 3436-48.
-
(2009)
FASEB J
, vol.23
, Issue.10
, pp. 3436-3448
-
-
Elimova, E.1
Kisilevsky, R.2
Ancsin, J.B.3
-
27
-
-
13444278866
-
Chondroitin 6-sulphate synthesis is up-regulated in injured CNS, induced by injury-related cytokines and enhanced in axon-growth inhibitory glia
-
Properzi, F.; Carulli, D.; Asher, R.A.; Muir, E.; Camargo, L.M.; van Kuppevelt, T.H.; ten Dam, G.B.; Furukawa, Y.; Mikami, T.; Sugahara, K.; Toida, T.; Geller, H.M.; Fawcett, J.W., Chondroitin 6-sulphate synthesis is up-regulated in injured CNS, induced by injury-related cytokines and enhanced in axon-growth inhibitory glia. Eur. J. Neurosci., 2005, 21 (2), 378-90.
-
(2005)
Eur. J. Neurosci.
, vol.21
, Issue.2
, pp. 378-390
-
-
Properzi, F.1
Carulli, D.2
Asher, R.A.3
Muir, E.4
Camargo, L.M.5
van Kuppevelt, T.H.6
ten Dam, G.B.7
Furukawa, Y.8
Mikami, T.9
Sugahara, K.10
Toida, T.11
Geller, H.M.12
Fawcett, J.W.13
-
28
-
-
0037061426
-
Chondroitinase ABC promotes functional recovery after spinal cord injury
-
Bradbury, E.J.; Moon, L.D.; Popat, R.J.; King, V.R.; Bennett, G.S.; Patel, P.N.; Fawcett, J.W.; McMahon, S.B., Chondroitinase ABC promotes functional recovery after spinal cord injury. Nature, 2002, 416 (6881), 636-40.
-
(2002)
Nature
, vol.416
, Issue.6881
, pp. 636-640
-
-
Bradbury, E.J.1
Moon, L.D.2
Popat, R.J.3
King, V.R.4
Bennett, G.S.5
Patel, P.N.6
Fawcett, J.W.7
McMahon, S.B.8
-
29
-
-
67349169961
-
Insights on a new path of pre-mitochondrial apoptosis regulation by a glycosaminoglycan mimetic
-
Yue, X.L.; Lehri, S.; Li, P.; Barbier-Chassefiere, V.; Petit, E.; Huang, Q.F.; Albanese, P.; Barritault, D.; Caruelle, J.P.; Papy-Garcia, D.; Morin, C., Insights on a new path of pre-mitochondrial apoptosis regulation by a glycosaminoglycan mimetic. Cell Death Differ., 2009, 16 (5), 770-81.
-
(2009)
Cell Death Differ
, vol.16
, Issue.5
, pp. 770-781
-
-
Yue, X.L.1
Lehri, S.2
Li, P.3
Barbier-Chassefiere, V.4
Petit, E.5
Huang, Q.F.6
Albanese, P.7
Barritault, D.8
Caruelle, J.P.9
Papy-Garcia, D.10
Morin, C.11
-
30
-
-
51249105318
-
Extracellular matrix of the central nervous system: From neglect to challenge
-
Zimmermann, D.R.; Dours-Zimmermann, M.T., Extracellular matrix of the central nervous system: from neglect to challenge. Histochem. Cell Biol., 2008, 130 (4), 635-53.
-
(2008)
Histochem. Cell Biol.
, vol.130
, Issue.4
, pp. 635-653
-
-
Zimmermann, D.R.1
Dours-Zimmermann, M.T.2
-
31
-
-
0141987856
-
Recent advances in the structural biology of chondroitin sulfate and dermatan sulfate
-
Sugahara, K.; Mikami, T.; Uyama, T.; Mizuguchi, S.; Nomura, K.; Kitagawa, H., Recent advances in the structural biology of chondroitin sulfate and dermatan sulfate. Curr. Opin. Struct. Biol., 2003, 13 (5), 612-20.
-
(2003)
Curr. Opin. Struct. Biol.
, vol.13
, Issue.5
, pp. 612-620
-
-
Sugahara, K.1
Mikami, T.2
Uyama, T.3
Mizuguchi, S.4
Nomura, K.5
Kitagawa, H.6
-
32
-
-
33747618728
-
Sulfation patterns of glycosaminoglycans encode molecular recognition and activity
-
Gama, C.I.; Tully, S.E.; Sotogaku, N.; Clark, P.M.; Rawat, M.; Vaidehi, N.; Goddard, W.A., 3rd; Nishi, A.; Hsieh-Wilson, L.C., Sulfation patterns of glycosaminoglycans encode molecular recognition and activity. Nat. Chem. Biol., 2006, 2 (9), 467-73.
-
(2006)
Nat. Chem. Biol.
, vol.2
, Issue.9
, pp. 467-473
-
-
Gama, C.I.1
Tully, S.E.2
Sotogaku, N.3
Clark, P.M.4
Rawat, M.5
Vaidehi, N.6
Goddard 3rd, W.A.7
Nishi, A.8
Hsieh-Wilson, L.C.9
-
33
-
-
0036903815
-
Signalling by glial cell line-derived neurotrophic factor (GDNF) requires heparan sulphate glycosaminoglycan
-
Barnett, M.W.; Fisher, C.E.; Perona-Wright, G.; Davies, J.A., Signalling by glial cell line-derived neurotrophic factor (GDNF) requires heparan sulphate glycosaminoglycan. J. Cell Sci., 2002, 115 (Pt 23), 4495-503.
-
(2002)
J. Cell Sci.
, vol.115
, Issue.PART 23
, pp. 4495-4503
-
-
Barnett, M.W.1
Fisher, C.E.2
Perona-Wright, G.3
Davies, J.A.4
-
34
-
-
69749119998
-
Heparinbinding determinants of GDNF reduce its tissue distribution but are beneficial for the protection of nigral dopaminergic neurons
-
Piltonen, M.; Bespalov, M.M.; Ervasti, D.; Matilainen, T.; Sidorova, Y.A.; Rauvala, H.; Saarma, M.; Mannisto, P.T., Heparinbinding determinants of GDNF reduce its tissue distribution but are beneficial for the protection of nigral dopaminergic neurons. Exp. Neurol., 2009, 219 (2), 499-506.
-
(2009)
Exp. Neurol.
, vol.219
, Issue.2
, pp. 499-506
-
-
Piltonen, M.1
Bespalov, M.M.2
Ervasti, D.3
Matilainen, T.4
Sidorova, Y.A.5
Rauvala, H.6
Saarma, M.7
Mannisto, P.T.8
-
35
-
-
48349139005
-
Spatiotemporal expression of chondroitin sulfate sulfotransferases in the postnatal developing mouse cerebellum
-
Ishii, M.; Maeda, N., Spatiotemporal expression of chondroitin sulfate sulfotransferases in the postnatal developing mouse cerebellum. Glycobiology, 2008, 18 (8), 602-14.
-
(2008)
Glycobiology
, vol.18
, Issue.8
, pp. 602-614
-
-
Ishii, M.1
Maeda, N.2
-
36
-
-
33947645277
-
The role of chondroitin sulfate proteoglycans in regeneration and plasticity in the central nervous system
-
Galtrey, C.M.; Fawcett, J.W., The role of chondroitin sulfate proteoglycans in regeneration and plasticity in the central nervous system. Brain Res. Rev., 2007, 54 (1), 1-18.
-
(2007)
Brain Res. Rev.
, vol.54
, Issue.1
, pp. 1-18
-
-
Galtrey, C.M.1
Fawcett, J.W.2
-
37
-
-
71949089309
-
Amyloid formation by the model protein muscle acylphosphatase is accelerated by heparin and heparan sulphate through a scaffolding-based mechanism
-
Motamedi-Shad, N.; Monsellier, E.; Chiti, F., Amyloid formation by the model protein muscle acylphosphatase is accelerated by heparin and heparan sulphate through a scaffolding-based mechanism. J. Biochem., 2009, 146 (6), 805-14.
-
(2009)
J. Biochem.
, vol.146
, Issue.6
, pp. 805-814
-
-
Motamedi-Shad, N.1
Monsellier, E.2
Chiti, F.3
-
38
-
-
71949086967
-
Molecular pathogenesis of protein misfolding diseases: Pathological molecular environments versus quality control systems against misfolded proteins
-
Naiki, H.; Nagai, Y., Molecular pathogenesis of protein misfolding diseases: pathological molecular environments versus quality control systems against misfolded proteins. J. Biochem., 2009, 146 (6), 751-6.
-
(2009)
J. Biochem.
, vol.146
, Issue.6
, pp. 751-756
-
-
Naiki, H.1
Nagai, Y.2
-
39
-
-
70349218070
-
A critical assessment of the role of helical intermediates in amyloid formation by natively unfolded proteins and polypeptides
-
Abedini, A.; Raleigh, D.P., A critical assessment of the role of helical intermediates in amyloid formation by natively unfolded proteins and polypeptides. Protein Eng. Des. Sel., 2009, 22 (8), 453-9.
-
(2009)
Protein Eng. Des. Sel.
, vol.22
, Issue.8
, pp. 453-459
-
-
Abedini, A.1
Raleigh, D.P.2
-
40
-
-
0026468915
-
Localization of heparan sulfate glycosaminoglycan and proteoglycan core protein in aged brain and Alzheimer's disease
-
Su, J.H.; Cummings, B.J.; Cotman, C.W., Localization of heparan sulfate glycosaminoglycan and proteoglycan core protein in aged brain and Alzheimer's disease. Neuroscience, 1992, 51 (4), 801-13.
-
(1992)
Neuroscience
, vol.51
, Issue.4
, pp. 801-813
-
-
Su, J.H.1
Cummings, B.J.2
Cotman, C.W.3
-
41
-
-
33750353368
-
Nature and significance of the interactions between amyloid fibrils and biological polyelectrolytes
-
Calamai, M.; Kumita, J.R.; Mifsud, J.; Parrini, C.; Ramazzotti, M.; Ramponi, G.; Taddei, N.; Chiti, F.; Dobson, C.M., Nature and significance of the interactions between amyloid fibrils and biological polyelectrolytes. Biochemistry, 2006, 45 (42), 12806-15.
-
(2006)
Biochemistry
, vol.45
, Issue.42
, pp. 12806-12815
-
-
Calamai, M.1
Kumita, J.R.2
Mifsud, J.3
Parrini, C.4
Ramazzotti, M.5
Ramponi, G.6
Taddei, N.7
Chiti, F.8
Dobson, C.M.9
-
42
-
-
77957198890
-
Divergent heparin-induced fibrillation pathways of a prion amyloidogenic determinant
-
Bazar, E.; Jelinek, R., Divergent Heparin-Induced Fibrillation Pathways of a Prion Amyloidogenic Determinant. Chembiochem, 2010.
-
(2010)
Chembiochem
-
-
Bazar, E.1
Jelinek, R.2
-
43
-
-
33747769942
-
Alpha-synuclein structure, posttranslational modification and alternative splicing as aggregation enhancers
-
Beyer, K., Alpha-synuclein structure, posttranslational modification and alternative splicing as aggregation enhancers. Acta Neuropathol., 2006, 112 (3), 237-51.
-
(2006)
Acta Neuropathol
, vol.112
, Issue.3
, pp. 237-251
-
-
Beyer, K.1
-
44
-
-
0029257497
-
The core Alzheimer's peptide NAC forms amyloid fibrils which seed and are seeded by beta-amyloid: Is NAC a common trigger or target in neurodegenerative disease?
-
Han, H.; Weinreb, P.H.; Lansbury, P.T., Jr., The core Alzheimer's peptide NAC forms amyloid fibrils which seed and are seeded by beta-amyloid: is NAC a common trigger or target in neurodegenerative disease? Chem. Biol., 1995, 2 (3), 163-9.
-
(1995)
Chem. Biol.
, vol.2
, Issue.3
, pp. 163-169
-
-
Han, H.1
Weinreb, P.H.2
Lansbury Jr., P.T.3
-
45
-
-
0027489773
-
Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease
-
Ueda, K.; Fukushima, H.; Masliah, E.; Xia, Y.; Iwai, A.; Yoshimoto, M.; Otero, D.A.; Kondo, J.; Ihara, Y.; Saitoh, T., Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease. Proc. Natl. Acad. Sci. USA, 1993, 90 (23), 11282-6.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, Issue.23
, pp. 11282-11286
-
-
Ueda, K.1
Fukushima, H.2
Masliah, E.3
Xia, Y.4
Iwai, A.5
Yoshimoto, M.6
Otero, D.A.7
Kondo, J.8
Ihara, Y.9
Saitoh, T.10
-
46
-
-
34548620297
-
Neuropathology, biochemistry, and biophysics of alpha-synuclein aggregation
-
Uversky, V.N., Neuropathology, biochemistry, and biophysics of alpha-synuclein aggregation. J. Neurochem., 2007, 103 (1), 17-37.
-
(2007)
J. Neurochem.
, vol.103
, Issue.1
, pp. 17-37
-
-
Uversky, V.N.1
-
47
-
-
0032568534
-
Alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies
-
Spillantini, M.G.; Crowther, R.A.; Jakes, R.; Hasegawa, M.; Goedert, M., alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies. Proc. Natl. Acad. Sci. USA, 1998, 95 (11), 6469-73.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, Issue.11
, pp. 6469-6473
-
-
Spillantini, M.G.1
Crowther, R.A.2
Jakes, R.3
Hasegawa, M.4
Goedert, M.5
-
48
-
-
18344417178
-
Lewy bodies contain altered alpha-synuclein in brains of many familial Alzheimer's disease patients with mutations in presenilin and amyloid precursor protein genes
-
Lippa, C.F.; Fujiwara, H.; Mann, D.M.; Giasson, B.; Baba, M.; Schmidt, M.L.; Nee, L.E.; O'Connell, B.; Pollen, D.A.; St George- Hyslop, P.; Ghetti, B.; Nochlin, D.; Bird, T.D.; Cairns, N.J.; Lee, V.M.; Iwatsubo, T.; Trojanowski, J.Q., Lewy bodies contain altered alpha-synuclein in brains of many familial Alzheimer's disease patients with mutations in presenilin and amyloid precursor protein genes. Am. J. Pathol., 1998, 153 (5), 1365-70.
-
(1998)
Am. J. Pathol.
, vol.153
, Issue.5
, pp. 1365-1370
-
-
Lippa, C.F.1
Fujiwara, H.2
Mann, D.M.3
Giasson, B.4
Baba, M.5
Schmidt, M.L.6
Nee, L.E.7
O'Connell, B.8
Pollen, D.A.9
St George-Hyslop, P.10
Ghetti, B.11
Nochlin, D.12
Bird, T.D.13
Cairns, N.J.14
Lee, V.M.15
Iwatsubo, T.16
Trojanowski, J.Q.17
-
49
-
-
0032923260
-
Microtubuleassociated protein tau, heparan sulphate and alpha-synuclein in several neurodegenerative diseases with dementia
-
Spillantini, M.G.; Tolnay, M.; Love, S.; Goedert, M., Microtubuleassociated protein tau, heparan sulphate and alpha-synuclein in several neurodegenerative diseases with dementia. Acta Neuropathol., 1999, 97 (6), 585-94.
-
(1999)
Acta Neuropathol
, vol.97
, Issue.6
, pp. 585-594
-
-
Spillantini, M.G.1
Tolnay, M.2
Love, S.3
Goedert, M.4
-
50
-
-
0032990543
-
Antibodies to alpha-synuclein detect Lewy bodies in many Down's syndrome brains with Alzheimer's disease
-
Lippa, C.F.; Schmidt, M.L.; Lee, V.M.; Trojanowski, J.Q., Antibodies to alpha-synuclein detect Lewy bodies in many Down's syndrome brains with Alzheimer's disease. Ann. Neurol., 1999, 45 (3), 353-7.
-
(1999)
Ann. Neurol.
, vol.45
, Issue.3
, pp. 353-357
-
-
Lippa, C.F.1
Schmidt, M.L.2
Lee, V.M.3
Trojanowski, J.Q.4
-
51
-
-
0037333666
-
Staging of brain pathology related to sporadic Parkinson's disease
-
Braak, H.; Del Tredici, K.; Rub, U.; de Vos, R.A.; Jansen Steur, E.N.; Braak, E., Staging of brain pathology related to sporadic Parkinson's disease. Neurobiol. Aging, 2003, 24 (2), 197-211.
-
(2003)
Neurobiol. Aging
, vol.24
, Issue.2
, pp. 197-211
-
-
Braak, H.1
del Tredici, K.2
Rub, U.3
de Vos, R.A.4
Jansen Steur, E.N.5
Braak, E.6
-
52
-
-
2442700253
-
Alpha-synuclein in blood and brain from familial Parkinson disease with SNCA locus triplication
-
Miller, D.W.; Hague, S.M.; Clarimon, J.; Baptista, M.; Gwinn- Hardy, K.; Cookson, M.R.; Singleton, A.B., Alpha-synuclein in blood and brain from familial Parkinson disease with SNCA locus triplication. Neurology, 2004, 62 (10), 1835-8.
-
(2004)
Neurology
, vol.62
, Issue.10
, pp. 1835-1838
-
-
Miller, D.W.1
Hague, S.M.2
Clarimon, J.3
Baptista, M.4
Gwinn- hardy, K.5
Cookson, M.R.6
Singleton, A.B.7
-
53
-
-
73649130269
-
Pathogenesis of Parkinson's disease: Emerging role of molecular chaperones
-
Bandopadhyay, R.; de Belleroche, J., Pathogenesis of Parkinson's disease: emerging role of molecular chaperones. Trends Mol. Med., 16 (1), 27-36.
-
Trends Mol. Med.
, vol.16
, Issue.1
, pp. 27-36
-
-
Bandopadhyay, R.1
de Belleroche, J.2
-
54
-
-
33751019425
-
Levels of alphasynuclein mRNA in sporadic Parkinson disease patients
-
Chiba-Falek, O.; Lopez, G.J.; Nussbaum, R.L., Levels of alphasynuclein mRNA in sporadic Parkinson disease patients. Mov. Disord., 2006, 21 (10), 1703-8.
-
(2006)
Mov. Disord.
, vol.21
, Issue.10
, pp. 1703-1708
-
-
Chiba-Falek, O.1
Lopez, G.J.2
Nussbaum, R.L.3
-
55
-
-
0035941201
-
Metal-triggered structural transformations, aggregation, and fibrillation of human alphasynuclein. A possible molecular NK between Parkinson's disease and heavy metal exposure
-
Uversky, V.N.; Li, J.; Fink, A.L., Metal-triggered structural transformations, aggregation, and fibrillation of human alphasynuclein. A possible molecular NK between Parkinson's disease and heavy metal exposure. J. Biol. Chem., 2001, 276 (47), 44284-96.
-
(2001)
J. Biol. Chem.
, vol.276
, Issue.47
, pp. 44284-44296
-
-
Uversky, V.N.1
Li, J.2
Fink, A.L.3
-
56
-
-
0035941305
-
Stabilization of partially folded conformation during alpha-synuclein oligomerization in both purified and cytosolic preparations
-
Uversky, V.N.; Lee, H.J.; Li, J.; Fink, A.L.; Lee, S.J., Stabilization of partially folded conformation during alpha-synuclein oligomerization in both purified and cytosolic preparations. J. Biol. Chem., 2001, 276 (47), 43495-8.
-
(2001)
J. Biol. Chem.
, vol.276
, Issue.47
, pp. 43495-43498
-
-
Uversky, V.N.1
Lee, H.J.2
Li, J.3
Fink, A.L.4
Lee, S.J.5
-
57
-
-
0037177250
-
Molecular crowding accelerates fibrillization of alpha-synuclein: Could an increase in the cytoplasmic protein concentration induce Parkinson's disease?
-
Shtilerman, M.D.; Ding, T.T.; Lansbury, P.T., Jr., Molecular crowding accelerates fibrillization of alpha-synuclein: could an increase in the cytoplasmic protein concentration induce Parkinson's disease? Biochemistry, 2002, 41 (12), 3855-60.
-
(2002)
Biochemistry
, vol.41
, Issue.12
, pp. 3855-3860
-
-
Shtilerman, M.D.1
Ding, T.T.2
Lansbury Jr., P.T.3
-
58
-
-
0037181497
-
Accelerated alpha-synuclein fibrillation in crowded milieu
-
Uversky, V.N.; E, M.C.; Bower, K.S.; Li, J.; Fink, A.L., Accelerated alpha-synuclein fibrillation in crowded milieu. FEBS Lett, 2002, 515 (1-3), 99-103.
-
(2002)
FEBS Lett
, vol.515
, Issue.1-3
, pp. 99-103
-
-
-
59
-
-
16644393251
-
Absence of heparan sulfate proteoglycans in Lewy bodies and Lewy neurites in Parkinson's disease brains
-
van Horssen, J.; de Vos, R.A.; Steur, E.N.; David, G.; Wesseling, P.; de Waal, R.M.; Verbeek, M.M., Absence of heparan sulfate proteoglycans in Lewy bodies and Lewy neurites in Parkinson's disease brains. J. Alzheimers Dis., 2004, 6 (5), 469-74.
-
(2004)
J. Alzheimers Dis.
, vol.6
, Issue.5
, pp. 469-474
-
-
van Horssen, J.1
de Vos, R.A.2
Steur, E.N.3
David, G.4
Wesseling, P.5
de Waal, R.M.6
Verbeek, M.M.7
-
60
-
-
28444458083
-
Agrin binds alpha-synuclein and modulates alphasynuclein fibrillation
-
Liu, I.H.; Uversky, V.N.; Munishkina, L.A.; Fink, A.L.; Halfter, W.; Cole, G.J., Agrin binds alpha-synuclein and modulates alphasynuclein fibrillation. Glycobiology, 2005, 15 (12), 1320-31.
-
(2005)
Glycobiology
, vol.15
, Issue.12
, pp. 1320-1331
-
-
Liu, I.H.1
Uversky, V.N.2
Munishkina, L.A.3
Fink, A.L.4
Halfter, W.5
Cole, G.J.6
-
61
-
-
0026548720
-
Basic fibroblast growth factor binds to filamentous inclusions of neurodegenerative diseases
-
Perry, G.; Richey, P.; Siedlak, S.L.; Galloway, P.; Kawai, M.; Cras, P., Basic fibroblast growth factor binds to filamentous inclusions of neurodegenerative diseases. Brain Res., 1992, 579 (2), 350-2.
-
(1992)
Brain Res
, vol.579
, Issue.2
, pp. 350-352
-
-
Perry, G.1
Richey, P.2
Siedlak, S.L.3
Galloway, P.4
Kawai, M.5
Cras, P.6
-
62
-
-
0345008875
-
Agrin is a major heparan sulfate proteoglycan accumulating in Alzheimer's disease brain
-
Verbeek, M.M.; Otte-Holler, I.; van den Born, J.; van den Heuvel, L.P.; David, G.; Wesseling, P.; de Waal, R.M., Agrin is a major heparan sulfate proteoglycan accumulating in Alzheimer's disease brain. Am. J. Pathol., 1999, 155 (6), 2115-25.
-
(1999)
Am. J. Pathol.
, vol.155
, Issue.6
, pp. 2115-2125
-
-
Verbeek, M.M.1
Otte-Holler, I.2
van den Born, J.3
van den Heuvel, L.P.4
David, G.5
Wesseling, P.6
de Waal, R.M.7
-
63
-
-
65249184946
-
Current concepts in Alzheimer's disease: A multidisciplinary review
-
Minati, L.; Edginton, T.; Bruzzone, M.G.; Giaccone, G., Current concepts in Alzheimer's disease: a multidisciplinary review. Am. J. Alzheimers Dis. Other Demen, 2009, 24 (2), 95-121.
-
(2009)
Am. J. Alzheimers Dis. Other Demen.
, vol.24
, Issue.2
, pp. 95-121
-
-
Minati, L.1
Edginton, T.2
Bruzzone, M.G.3
Giaccone, G.4
-
64
-
-
0032058918
-
Evolution in the conceptualization of dementia and Alzheimer's disease: Greco-Roman period to the 1960s
-
Berchtold, N.C.; Cotman, C.W., Evolution in the conceptualization of dementia and Alzheimer's disease: Greco-Roman period to the 1960s. Neurobiol. Aging, 1998, 19 (3), 173-89.
-
(1998)
Neurobiol. Aging
, vol.19
, Issue.3
, pp. 173-189
-
-
Berchtold, N.C.1
Cotman, C.W.2
-
65
-
-
67651180986
-
The amyloid hypothesis for Alzheimer's disease: A critical reappraisal
-
Hardy, J., The amyloid hypothesis for Alzheimer's disease: a critical reappraisal. J. Neurochem., 2009, 110 (4), 1129-34.
-
(2009)
J. Neurochem.
, vol.110
, Issue.4
, pp. 1129-1134
-
-
Hardy, J.1
-
66
-
-
78649898216
-
Modulation of A{beta}42 fibrillogenesis by glycosaminoglycan structure
-
Valle-Delgado, J.J.; Alfonso-Prieto, M.; de Groot, N.S.; Ventura, S.; Samitier, J.; Rovira, C.; Fernandez-Busquets, X., Modulation of A{beta}42 fibrillogenesis by glycosaminoglycan structure. FASEB J., 2010.
-
(2010)
FASEB J
-
-
Valle-Delgado, J.J.1
Alfonso-Prieto, M.2
de Groot, N.S.3
Ventura, S.4
Samitier, J.5
Rovira, C.6
Fernandez-Busquets, X.7
-
67
-
-
0842307665
-
Amyloidosis of Alzheimer's Abeta peptides: Solid-state nuclear magnetic resonance, electron paramagnetic resonance, transmission electron microscopy, scanning transmission electron microscopy and atomic force microscopy studies
-
Antzutkin, O.N., Amyloidosis of Alzheimer's Abeta peptides: solid-state nuclear magnetic resonance, electron paramagnetic resonance, transmission electron microscopy, scanning transmission electron microscopy and atomic force microscopy studies. Magn. Reson. Chem., 2004, 42 (2), 231-46.
-
(2004)
Magn. Reson. Chem.
, vol.42
, Issue.2
, pp. 231-246
-
-
Antzutkin, O.N.1
-
68
-
-
0037422540
-
Amyloid beta -protein (Abeta) assembly: Abeta 40 and Abeta 42 oligomerize through distinct pathways
-
Bitan, G.; Kirkitadze, M.D.; Lomakin, A.; Vollers, S.S.; Benedek, G.B.; Teplow, D.B., Amyloid beta -protein (Abeta) assembly: Abeta 40 and Abeta 42 oligomerize through distinct pathways. Proc. Natl. Acad. Sci. USA, 2003, 100 (1), 330-5.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, Issue.1
, pp. 330-335
-
-
Bitan, G.1
Kirkitadze, M.D.2
Lomakin, A.3
Vollers, S.S.4
Benedek, G.B.5
Teplow, D.B.6
-
69
-
-
33645108790
-
High-resolution atomic force microscopy of soluble Abeta42 oligomers
-
Mastrangelo, I.A.; Ahmed, M.; Sato, T.; Liu, W.; Wang, C.; Hough, P.; Smith, S.O., High-resolution atomic force microscopy of soluble Abeta42 oligomers. J. Mol. Biol., 2006, 358 (1), 106-19.
-
(2006)
J. Mol. Biol.
, vol.358
, Issue.1
, pp. 106-119
-
-
Mastrangelo, I.A.1
Ahmed, M.2
Sato, T.3
Liu, W.4
Wang, C.5
Hough, P.6
Smith, S.O.7
-
70
-
-
47249109484
-
Recent structural and computational insights into conformational diseases
-
Fernandez-Busquets, X.; de Groot, N.S.; Fernandez, D.; Ventura, S., Recent structural and computational insights into conformational diseases. Curr. Med. Chem., 2008, 15 (13), 1336-49.
-
(2008)
Curr. Med. Chem.
, vol.15
, Issue.13
, pp. 1336-1349
-
-
Fernandez-Busquets, X.1
de Groot, N.S.2
Fernandez, D.3
Ventura, S.4
-
71
-
-
23444450012
-
Fine structure study of Abeta1-42 fibrillogenesis with atomic force microscopy
-
Arimon, M.; Diez-Perez, I.; Kogan, M.J.; Durany, N.; Giralt, E.; Sanz, F.; Fernandez-Busquets, X., Fine structure study of Abeta1-42 fibrillogenesis with atomic force microscopy. FASEB J., 2005, 19 (10), 1344-6.
-
(2005)
FASEB J
, vol.19
, Issue.10
, pp. 1344-1346
-
-
Arimon, M.1
Diez-Perez, I.2
Kogan, M.J.3
Durany, N.4
Giralt, E.5
Sanz, F.6
Fernandez-Busquets, X.7
-
72
-
-
28444442999
-
3D structure of Alzheimer's amyloid-beta(1-42) fibrils
-
Luhrs, T.; Ritter, C.; Adrian, M.; Riek-Loher, D.; Bohrmann, B.; Dobeli, H.; Schubert, D.; Riek, R., 3D structure of Alzheimer's amyloid-beta(1-42) fibrils. Proc. Natl. Acad. Sci. USA, 2005, 102 (48), 17342-7.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, Issue.48
, pp. 17342-17347
-
-
Luhrs, T.1
Ritter, C.2
Adrian, M.3
Riek-Loher, D.4
Bohrmann, B.5
Dobeli, H.6
Schubert, D.7
Riek, R.8
-
73
-
-
0142124707
-
Amyloidosis: New strategies for treatment
-
Hirschfield, G.M.; Hawkins, P.N., Amyloidosis: new strategies for treatment. Int. J. Biochem. Cell Biol., 2003, 35 (12), 1608-13.
-
(2003)
Int. J. Biochem. Cell Biol.
, vol.35
, Issue.12
, pp. 1608-1613
-
-
Hirschfield, G.M.1
Hawkins, P.N.2
-
74
-
-
11544279355
-
Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins
-
Lambert, M.P.; Barlow, A.K.; Chromy, B.A.; Edwards, C.; Freed, R.; Liosatos, M.; Morgan, T.E.; Rozovsky, I.; Trommer, B.; Viola, K.L.; Wals, P.; Zhang, C.; Finch, C.E.; Krafft, G.A.; Klein, W.L., Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins. Proc. Natl. Acad. Sci. USA, 1998, 95 (11), 6448-53.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, Issue.11
, pp. 6448-6453
-
-
Lambert, M.P.1
Barlow, A.K.2
Chromy, B.A.3
Edwards, C.4
Freed, R.5
Liosatos, M.6
Morgan, T.E.7
Rozovsky, I.8
Trommer, B.9
Viola, K.L.10
Wals, P.11
Zhang, C.12
Finch, C.E.13
Krafft, G.A.14
Klein, W.L.15
-
75
-
-
0242668337
-
Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis
-
Kayed, R.; Head, E.; Thompson, J.L.; McIntire, T.M.; Milton, S.C.; Cotman, C.W.; Glabe, C.G., Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis. Science, 2003, 300 (5618), 486-9.
-
(2003)
Science
, vol.300
, Issue.5618
, pp. 486-489
-
-
Kayed, R.1
Head, E.2
Thompson, J.L.3
McIntire, T.M.4
Milton, S.C.5
Cotman, C.W.6
Glabe, C.G.7
-
76
-
-
33745228920
-
The various aggregation states of beta-amyloid 1-42 mediate different effects on oxidative stress, neurodegeneration, and BACE-1 expression
-
Tamagno, E.; Bardini, P.; Guglielmotto, M.; Danni, O.; Tabaton, M., The various aggregation states of beta-amyloid 1-42 mediate different effects on oxidative stress, neurodegeneration, and BACE-1 expression. Free Radic. Biol. Med., 2006, 41 (2), 202-12.
-
(2006)
Free Radic. Biol. Med.
, vol.41
, Issue.2
, pp. 202-212
-
-
Tamagno, E.1
Bardini, P.2
Guglielmotto, M.3
Danni, O.4
Tabaton, M.5
-
77
-
-
0037041426
-
Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo
-
Walsh, D.M.; Klyubin, I.; Fadeeva, J.V.; Cullen, W.K.; Anwyl, R.; Wolfe, M.S.; Rowan, M.J.; Selkoe, D.J., Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo. Nature, 2002, 416 (6880), 535-9.
-
(2002)
Nature
, vol.416
, Issue.6880
, pp. 535-539
-
-
Walsh, D.M.1
Klyubin, I.2
Fadeeva, J.V.3
Cullen, W.K.4
Anwyl, R.5
Wolfe, M.S.6
Rowan, M.J.7
Selkoe, D.J.8
-
78
-
-
0036669881
-
Amyloid-beta oligomers: Their production, toxicity and therapeutic inhibition
-
Walsh, D.M.; Klyubin, I.; Fadeeva, J.V.; Rowan, M.J.; Selkoe, D.J., Amyloid-beta oligomers: their production, toxicity and therapeutic inhibition. Biochem. Soc. Trans., 2002, 30 (4), 552-7.
-
(2002)
Biochem. Soc. Trans.
, vol.30
, Issue.4
, pp. 552-557
-
-
Walsh, D.M.1
Klyubin, I.2
Fadeeva, J.V.3
Rowan, M.J.4
Selkoe, D.J.5
-
79
-
-
57749091860
-
Sulfated polysaccharides promote the assembly of amyloid beta(1-42) peptide into stable fibrils of reduced cytotoxicity
-
Bravo, R.; Arimon, M.; Valle-Delgado, J.J.; Garcia, R.; Durany, N.; Castel, S.; Cruz, M.; Ventura, S.; Fernandez-Busquets, X., Sulfated polysaccharides promote the assembly of amyloid beta(1-42) peptide into stable fibrils of reduced cytotoxicity. J. Biol. Chem., 2008, 283 (47), 32471-83.
-
(2008)
J. Biol. Chem.
, vol.283
, Issue.47
, pp. 32471-33283
-
-
Bravo, R.1
Arimon, M.2
Valle-Delgado, J.J.3
Garcia, R.4
Durany, N.5
Castel, S.6
Cruz, M.7
Ventura, S.8
Fernandez-Busquets, X.9
-
80
-
-
0042703654
-
Amyloidogenesis: Historical and modern observations point to heparan sulfate proteoglycans as a major culprit
-
Ancsin, J.B., Amyloidogenesis: historical and modern observations point to heparan sulfate proteoglycans as a major culprit. Amyloid, 2003, 10 (2), 67-79.
-
(2003)
Amyloid
, vol.10
, Issue.2
, pp. 67-79
-
-
Ancsin, J.B.1
-
81
-
-
0024539012
-
Sulfated glycosaminoglycans in amyloid plaques of prion diseases
-
Snow, A.D.; Kisilevsky, R.; Willmer, J.; Prusiner, S.B.; DeArmond, S.J., Sulfated glycosaminoglycans in amyloid plaques of prion diseases. Acta Neuropathol., 1989, 77 (4), 337-42.
-
(1989)
Acta Neuropathol
, vol.77
, Issue.4
, pp. 337-342
-
-
Snow, A.D.1
Kisilevsky, R.2
Willmer, J.3
Prusiner, S.B.4
Dearmond, S.J.5
-
82
-
-
0038376613
-
Heparan sulphate proteoglycans in Alzheimer's disease and amyloid-related disorders
-
van Horssen, J.; Wesseling, P.; van den Heuvel, L.P.; de Waal, R.M.; Verbeek, M.M., Heparan sulphate proteoglycans in Alzheimer's disease and amyloid-related disorders. Lancet Neurol., 2003, 2 (8), 482-92.
-
(2003)
Lancet Neurol
, vol.2
, Issue.8
, pp. 482-492
-
-
van Horssen, J.1
Wesseling, P.2
van den Heuvel, L.P.3
de Waal, R.M.4
Verbeek, M.M.5
-
83
-
-
0030725311
-
Perlecan binds to the beta-amyloid proteins (A beta) of Alzheimer's disease, accelerates A beta fibril formation, and maintains A beta fibril stability
-
Castillo, G.M.; Ngo, C.; Cummings, J.; Wight, T.N.; Snow, A.D., Perlecan binds to the beta-amyloid proteins (A beta) of Alzheimer's disease, accelerates A beta fibril formation, and maintains A beta fibril stability. J. Neurochem., 1997, 69 (6), 2452-65.
-
(1997)
J. Neurochem.
, vol.69
, Issue.6
, pp. 2452-2465
-
-
Castillo, G.M.1
Ngo, C.2
Cummings, J.3
Wight, T.N.4
Snow, A.D.5
-
84
-
-
0028792576
-
Heparan sulfate and chondroitin sulfate glycosaminoglycan attenuate beta-amyloid(25-35) induced neurodegeneration in cultured hippocampal neurons
-
Woods, A.G.; Cribbs, D.H.; Whittemore, E.R.; Cotman, C.W., Heparan sulfate and chondroitin sulfate glycosaminoglycan attenuate beta-amyloid(25-35) induced neurodegeneration in cultured hippocampal neurons. Brain Res., 1995, 697 (1-2), 53-62.
-
(1995)
Brain Res
, vol.697
, Issue.1-2
, pp. 53-62
-
-
Woods, A.G.1
Cribbs, D.H.2
Whittemore, E.R.3
Cotman, C.W.4
-
85
-
-
65949108598
-
Exploiting a (13)C-labelled heparin analogue for in situ solid-state NMR investigations of peptide-glycan interactions within amyloid fibrils
-
Madine, J.; Clayton, J.C.; Yates, E.A.; Middleton, D.A., Exploiting a (13)C-labelled heparin analogue for in situ solid-state NMR investigations of peptide-glycan interactions within amyloid fibrils. Org. Biomol. Chem., 2009, 7 (11), 2414-20.
-
(2009)
Org. Biomol. Chem.
, vol.7
, Issue.11
, pp. 2414-2420
-
-
Madine, J.1
Clayton, J.C.2
Yates, E.A.3
Middleton, D.A.4
-
86
-
-
77956512204
-
Limited expression of heparan sulfate proteoglycans associated with Abeta deposits in the APPswe/PS1dE9 mouse model for Alzheimer's disease
-
Timmer, N.M.; Herbert, M.K.; Kleinovink, J.W.; Kiliaan, A.J.; de Waal, R.M.; Verbeek, M.M., Limited expression of heparan sulfate proteoglycans associated with Abeta deposits in the APPswe/PS1dE9 mouse model for Alzheimer's disease. Neuropathol. Appl. Neurobiol., 2010.
-
(2010)
Neuropathol. Appl. Neurobiol.
-
-
Timmer, N.M.1
Herbert, M.K.2
Kleinovink, J.W.3
Kiliaan, A.J.4
de Waal, R.M.5
Verbeek, M.M.6
-
87
-
-
0033572813
-
Interactions of Alzheimer amyloid-beta peptides with glycosaminoglycans effects on fibril nucleation and growth
-
McLaurin, J.; Franklin, T.; Zhang, X.; Deng, J.; Fraser, P.E., Interactions of Alzheimer amyloid-beta peptides with glycosaminoglycans effects on fibril nucleation and growth. Eur. J. Biochem., 1999, 266 (3), 1101-10.
-
(1999)
Eur. J. Biochem.
, vol.266
, Issue.3
, pp. 1101-1110
-
-
McLaurin, J.1
Franklin, T.2
Zhang, X.3
Deng, J.4
Fraser, P.E.5
-
88
-
-
0033026552
-
The sulfate moieties of glycosaminoglycans are critical for the enhancement of beta-amyloid protein fibril formation
-
Castillo, G.M.; Lukito, W.; Wight, T.N.; Snow, A.D., The sulfate moieties of glycosaminoglycans are critical for the enhancement of beta-amyloid protein fibril formation. J. Neurochem., 1999, 72 (4), 1681-7.
-
(1999)
J. Neurochem.
, vol.72
, Issue.4
, pp. 1681-1687
-
-
Castillo, G.M.1
Lukito, W.2
Wight, T.N.3
Snow, A.D.4
-
89
-
-
0029907548
-
Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans
-
Goedert, M.; Jakes, R.; Spillantini, M.G.; Hasegawa, M.; Smith, M.J.; Crowther, R.A. Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans. Nature, 1996, 383 (6600), 550-3.
-
(1996)
Nature
, vol.383
, Issue.6600
, pp. 550-553
-
-
Goedert, M.1
Jakes, R.2
Spillantini, M.G.3
Hasegawa, M.4
Smith, M.J.5
Crowther, R.A.6
-
90
-
-
78649898216
-
Modulation of A{beta}42 fibrillogenesis by glycosaminoglycan structure
-
Valle-Delgado, J.J.; Alfonso-Prieto, M.; de Groot, N.S.; Ventura, S.; Samitier, J.; Rovira, C.; Fernandez-Busquets, X. Modulation of A{beta}42 fibrillogenesis by glycosaminoglycan structure. FASEB J.
-
FASEB J
-
-
Valle-Delgado, J.J.1
Alfonso-Prieto, M.2
de Groot, N.S.3
Ventura, S.4
Samitier, J.5
Rovira, C.6
Fernandez-Busquets, X.7
-
91
-
-
2442483898
-
Peripheral treatment with enoxaparin, a low molecular weight heparin, reduces plaques and beta-amyloid accumulation in a mouse model of Alzheimer's disease
-
Bergamaschini, L.; Rossi, E.; Storini, C.; Pizzimenti, S.; Distaso, M.; Perego, C.; De Luigi, A.; Vergani, C.; De Simoni, M.G., Peripheral treatment with enoxaparin, a low molecular weight heparin, reduces plaques and beta-amyloid accumulation in a mouse model of Alzheimer's disease. J. Neurosci., 2004, 24 (17), 4181-6.
-
(2004)
J. Neurosci.
, vol.24
, Issue.17
, pp. 4181-4186
-
-
Bergamaschini, L.1
Rossi, E.2
Storini, C.3
Pizzimenti, S.4
Distaso, M.5
Perego, C.6
de Luigi, A.7
Vergani, C.8
de Simoni, M.G.9
-
92
-
-
70350749549
-
Alzheimer's disease: Another target for heparin therapy
-
Bergamaschini, L.; Rossi, E.; Vergani, C.; De Simoni, M.G., Alzheimer's disease: another target for heparin therapy. Scientific World Journal, 2009, 9, 891-908.
-
(2009)
Scientific World Journal
, vol.9
, pp. 891-908
-
-
Bergamaschini, L.1
Rossi, E.2
Vergani, C.3
de Simoni, M.G.4
-
93
-
-
70350495442
-
Reexamining Alzheimer's disease: Evidence for a protective role for amyloid-beta protein precursor and amyloid-beta
-
Castellani, R.J.; Lee, H.G.; Siedlak, S.L.; Nunomura, A.; Hayashi, T.; Nakamura, M.; Zhu, X.; Perry, G.; Smith, M.A., Reexamining Alzheimer's disease: evidence for a protective role for amyloid-beta protein precursor and amyloid-beta. J. Alzheimers Dis., 2009, 18 (2), 447-52.
-
(2009)
J. Alzheimers Dis.
, vol.18
, Issue.2
, pp. 447-452
-
-
Castellani, R.J.1
Lee, H.G.2
Siedlak, S.L.3
Nunomura, A.4
Hayashi, T.5
Nakamura, M.6
Zhu, X.7
Perry, G.8
Smith, M.A.9
-
94
-
-
6344287664
-
Anionic contribution for fibrous maturation of protofibrillar assemblies of the human tau repeat domain in a fluoroalcohol solution
-
Konno, T.; Oiki, S.; Hasegawa, K.; Naiki, H., Anionic contribution for fibrous maturation of protofibrillar assemblies of the human tau repeat domain in a fluoroalcohol solution. Biochemistry, 2004, 43 (42), 13613-20.
-
(2004)
Biochemistry
, vol.43
, Issue.42
, pp. 13613-13620
-
-
Konno, T.1
Oiki, S.2
Hasegawa, K.3
Naiki, H.4
-
95
-
-
70349570600
-
Aberrant phosphorylation in the pathogenesis of Alzheimer's disease
-
Chung, S.H., Aberrant phosphorylation in the pathogenesis of Alzheimer's disease. BMB Re.p, 2009, 42 (8), 467-74.
-
(2009)
BMB Re.
, vol.42
, Issue.8
, pp. 467-474
-
-
Chung, S.H.1
-
96
-
-
61849088424
-
Tau phosphorylation: The therapeutic challenge for neurodegenerative disease
-
Hanger, D.P.; Anderton, B.H.; Noble, W., Tau phosphorylation: the therapeutic challenge for neurodegenerative disease. Trends Mol Med, 2009, 15 (3), 112-9.
-
(2009)
Trends Mol Med
, vol.15
, Issue.3
, pp. 112-119
-
-
Hanger, D.P.1
Anderton, B.H.2
Noble, W.3
-
97
-
-
0033583176
-
Heparin-induced conformational change in microtubule-associated protein Tau as detected by chemical crosslinking and phosphopeptide mapping
-
Paudel, H.K.; Li, W., Heparin-induced conformational change in microtubule-associated protein Tau as detected by chemical crosslinking and phosphopeptide mapping. J. Biol. Chem., 1999, 274 (12), 8029-38.
-
(1999)
J. Biol. Chem.
, vol.274
, Issue.12
, pp. 8029-8038
-
-
Paudel, H.K.1
Li, W.2
-
98
-
-
61349145507
-
Development of tau aggregation inhibitors for Alzheimer's disease
-
Bulic, B.; Pickhardt, M.; Schmidt, B.; Mandelkow, E.M.; Waldmann, H.; Mandelkow, E., Development of tau aggregation inhibitors for Alzheimer's disease. Angew. Chem. Int. Ed. Engl., 2009, 48 (10), 1740-52.
-
(2009)
Angew. Chem. Int. Ed. Engl.
, vol.48
, Issue.10
, pp. 1740-1752
-
-
Bulic, B.1
Pickhardt, M.2
Schmidt, B.3
Mandelkow, E.M.4
Waldmann, H.5
Mandelkow, E.6
-
99
-
-
70349638299
-
Advances in taufocused drug discovery for Alzheimer's disease and related tauopathies
-
Brunden, K.R.; Trojanowski, J.Q.; Lee, V.M., Advances in taufocused drug discovery for Alzheimer's disease and related tauopathies. Nat. Rev. Drug Discov., 2009, 8 (10), 783-93.
-
(2009)
Nat. Rev. Drug Discov.
, vol.8
, Issue.10
, pp. 783-793
-
-
Brunden, K.R.1
Trojanowski, J.Q.2
Lee, V.M.3
-
100
-
-
67649273927
-
Propagation of tau misfolding from the outside to the inside of a cell
-
Frost, B.; Jacks, R.L.; Diamond, M.I., Propagation of tau misfolding from the outside to the inside of a cell. J. Biol. Chem., 2009, 284 (19), 12845-52.
-
(2009)
J. Biol. Chem.
, vol.284
, Issue.19
, pp. 12845-12852
-
-
Frost, B.1
Jacks, R.L.2
Diamond, M.I.3
-
101
-
-
67650077008
-
Transmission and spreading of tauopathy in transgenic mouse brain
-
Clavaguera, F.; Bolmont, T.; Crowther, R.A.; Abramowski, D.; Frank, S.; Probst, A.; Fraser, G.; Stalder, A.K.; Beibel, M.; Staufenbiel, M.; Jucker, M.; Goedert, M.; Tolnay, M., Transmission and spreading of tauopathy in transgenic mouse brain. Nat. Cell Biol., 2009, 11 (7), 909-13.
-
(2009)
Nat. Cell Biol.
, vol.11
, Issue.7
, pp. 909-913
-
-
Clavaguera, F.1
Bolmont, T.2
Crowther, R.A.3
Abramowski, D.4
Frank, S.5
Probst, A.6
Fraser, G.7
Stalder, A.K.8
Beibel, M.9
Staufenbiel, M.10
Jucker, M.11
Goedert, M.12
Tolnay, M.13
-
102
-
-
77951810969
-
Causes versus effects: The increasing complexities of Alzheimer's disease pathogenesis
-
Mondragon-Rodriguez, S.; Basurto-Islas, G.; Lee, H.G.; Perry, G.; Zhu, X.; Castellani, R.J.; Smith, M.A., Causes versus effects: the increasing complexities of Alzheimer's disease pathogenesis. Expert Rev. Neurother., 10 (5), 683-91.
-
Expert Rev. Neurother.
, vol.10
, Issue.5
, pp. 683-691
-
-
Mondragon-Rodriguez, S.1
Basurto-Islas, G.2
Lee, H.G.3
Perry, G.4
Zhu, X.5
Castellani, R.J.6
Smith, M.A.7
-
103
-
-
24644448839
-
The most infectious prion protein particles
-
Silveira, J.R.; Raymond, G.J.; Hughson, A.G.; Race, R.E.; Sim, V.L.; Hayes, S.F.; Caughey, B., The most infectious prion protein particles. Nature, 2005, 437 (7056), 257-61.
-
(2005)
Nature
, vol.437
, Issue.7056
, pp. 257-261
-
-
Silveira, J.R.1
Raymond, G.J.2
Hughson, A.G.3
Race, R.E.4
Sim, V.L.5
Hayes, S.F.6
Caughey, B.7
-
104
-
-
77951183978
-
Prion-like disorders: Blurring the divide between transmissibility and infectivity
-
Cushman, M.; Johnson, B.S.; King, O.D.; Gitler, A.D.; Shorter, J., Prion-like disorders: blurring the divide between transmissibility and infectivity. J. Cell Sci., 2010, 123 (Pt 8), 1191-201.
-
(2010)
J. Cell Sci.
, vol.123
, Issue.PART 8
, pp. 1191-1201
-
-
Cushman, M.1
Johnson, B.S.2
King, O.D.3
Gitler, A.D.4
Shorter, J.5
-
105
-
-
39549106489
-
Amyloidogenic properties of the prion protein fragment PrP(185-208): Comparison with Alzheimer's peptide Abeta(1-28), influence of heparin and cell toxicity
-
Cortijo-Arellano, M.; Ponce, J.; Durany, N.; Cladera, J., Amyloidogenic properties of the prion protein fragment PrP(185-208): comparison with Alzheimer's peptide Abeta(1-28), influence of heparin and cell toxicity. Biochem. Biophys. Res. Commun., 2008, 368 (2), 238-42.
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.368
, Issue.2
, pp. 238-242
-
-
Cortijo-Arellano, M.1
Ponce, J.2
Durany, N.3
Cladera, J.4
-
106
-
-
61549099652
-
Mechanisms of prion protein aggregation
-
Fontaine, S.N.; Brown, D.R., Mechanisms of prion protein aggregation. Protein Pept. Lett., 2009, 16 (1), 14-26.
-
(2009)
Protein Pept. Lett.
, vol.16
, Issue.1
, pp. 14-26
-
-
Fontaine, S.N.1
Brown, D.R.2
-
107
-
-
33745040961
-
Therapeutic applications of glycosaminoglycans
-
Volpi, N., Therapeutic applications of glycosaminoglycans. Curr. Med. Chem., 2006, 13 (15), 1799-810.
-
(2006)
Curr. Med. Chem.
, vol.13
, Issue.15
, pp. 1799-1810
-
-
Volpi, N.1
-
108
-
-
28444448086
-
Influence of heparin and dendrimers on the aggregation of two amyloid peptides related to Alzheimer's and prion diseases
-
Klajnert, B.; Cortijo-Arellano, M.; Bryszewska, M.; Cladera, J., Influence of heparin and dendrimers on the aggregation of two amyloid peptides related to Alzheimer's and prion diseases. Biochem. Biophys. Res. Commun., 2006, 339 (2), 577-82.
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.339
, Issue.2
, pp. 577-582
-
-
Klajnert, B.1
Cortijo-Arellano, M.2
Bryszewska, M.3
Cladera, J.4
|