-
1
-
-
0042703654
-
Amyloidogenesis: Historical and modern observations point to heparan sulfate proteoglycans as a major culprit
-
Ancsin, J.B. (2003) Amyloidogenesis: Historical and modern observations point to heparan sulfate proteoglycans as a major culprit. Amyloid, 10, 67-79.
-
(2003)
Amyloid
, vol.10
, pp. 67-79
-
-
Ancsin, J.B.1
-
2
-
-
0344298995
-
Alpha-synuclein accumulates in Lewy bodies in Parkinson's disease and dementia with Lewy bodies but not in Alzheimer's disease beta-amyloid plaque cores
-
Bayer, T.A., Jakala, P., Hartmann, T., Havas, L., McLean, C., Culvenor, J.G., Li, Q.X., Masters, C.L., Falkai, P., and Beyreuther, K. (1999) Alpha-synuclein accumulates in Lewy bodies in Parkinson's disease and dementia with Lewy bodies but not in Alzheimer's disease beta-amyloid plaque cores. Neurosci. Lett., 266, 213-216.
-
(1999)
Neurosci. Lett.
, vol.266
, pp. 213-216
-
-
Bayer, T.A.1
Jakala, P.2
Hartmann, T.3
Havas, L.4
McLean, C.5
Culvenor, J.G.6
Li, Q.X.7
Masters, C.L.8
Falkai, P.9
Beyreuther, K.10
-
3
-
-
0034603407
-
Agrin and microvascular damage in Alzheimer's disease
-
Berzin, T.M., Zipser, B.D., Rafii, M.S., Kuo-Leblanc, V., Yancopoulos, G.D., Glass, D.J., Fallon, J.R., and Stopa, E.G. (2000) Agrin and microvascular damage in Alzheimer's disease. Neurobiol. Aging, 21, 349-355.
-
(2000)
Neurobiol. Aging
, vol.21
, pp. 349-355
-
-
Berzin, T.M.1
Zipser, B.D.2
Rafii, M.S.3
Kuo-Leblanc, V.4
Yancopoulos, G.D.5
Glass, D.J.6
Fallon, J.R.7
Stopa, E.G.8
-
4
-
-
0027526419
-
Release of excess amyloid beta protein from a mutant amyloid beta protein precursor
-
Cai, X.D., Golde, T.E., and Younkin, S.G. (1993) Release of excess amyloid beta protein from a mutant amyloid beta protein precursor. Science, 259, 514-516.
-
(1993)
Science
, vol.259
, pp. 514-516
-
-
Cai, X.D.1
Golde, T.E.2
Younkin, S.G.3
-
5
-
-
0030841343
-
Conformational disease
-
Carrell, R.W. and Lomas, D.A. (1997) Conformational disease. Lancet, 350, 134-138.
-
(1997)
Lancet
, vol.350
, pp. 134-138
-
-
Carrell, R.W.1
Lomas, D.A.2
-
6
-
-
0031895939
-
Sulfate content and specific glycosaminoglycan backbone of perlecan are critical for perlecan's enhancement of islet amyloid peptide (amylin) fibril formation
-
Castillo, G.M., Cummings, J.A., Yang, W., Judge, M.E., Sheardown, M.J., Rimvall, K., Hansen, J.B., and Snow, A.D. (1998) Sulfate content and specific glycosaminoglycan backbone of perlecan are critical for perlecan's enhancement of islet amyloid peptide (amylin) fibril formation. Diabetes, 47, 612-620.
-
(1998)
Diabetes
, vol.47
, pp. 612-620
-
-
Castillo, G.M.1
Cummings, J.A.2
Yang, W.3
Judge, M.E.4
Sheardown, M.J.5
Rimvall, K.6
Hansen, J.B.7
Snow, A.D.8
-
7
-
-
0026745610
-
Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production
-
Citron, M., Oltersdorf, T., Haass, C., McConlogue, L., Hung, A.Y., Seubert, P., Vigo-Pelfrey, C., Lieberburg, I., and Slekoe, D.J. (1992) Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production. Nature, 360, 762-674.
-
(1992)
Nature
, vol.360
, pp. 674-762
-
-
Citron, M.1
Oltersdorf, T.2
Haass, C.3
McConlogue, L.4
Hung, A.Y.5
Seubert, P.6
Vigo-Pelfrey, C.7
Lieberburg, I.8
Slekoe, D.J.9
-
8
-
-
0031023262
-
Expression of agrin in the developing and adult rat brain
-
Cohen, N.A., Kaufmann, W.E., Worley, P.F., and Rupp, F. (1997) Expression of agrin in the developing and adult rat brain. Neuroscience, 76, 581-596.
-
(1997)
Neuroscience
, vol.76
, pp. 581-596
-
-
Cohen, N.A.1
Kaufmann, W.E.2
Worley, P.F.3
Rupp, F.4
-
9
-
-
0037022186
-
Heparin and other glycosaminoglycans stimulate the formation of amyloid fibrils from α-synuclein in vitro
-
Cohlberg, J.A., Li, J., Uversky, V.N., and Fink, A.L. (2002) Heparin and other glycosaminoglycans stimulate the formation of amyloid fibrils from α-synuclein in vitro. Biochemistry, 41, 1502-1511.
-
(2002)
Biochemistry
, vol.41
, pp. 1502-1511
-
-
Cohlberg, J.A.1
Li, J.2
Uversky, V.N.3
Fink, A.L.4
-
10
-
-
28444440201
-
Glycosaminoglycans, proteoglycans and conformational disorders
-
(in press) Uversky, V. and Fink, A.L. (eds), Kluwer Academic/Plenum Publishers, New York
-
Cole, G.J. and Liu, I.-H. (in press) Glycosaminoglycans, proteoglycans and conformational disorders. In Uversky, V. and Fink, A.L. (eds), Protein Misfolding, Aggregation and Conformational Diseases, Vol. I, Protein Aggregation and Conformational Diseases. Kluwer Academic/Plenum Publishers, New York.
-
Protein Misfolding, Aggregation and Conformational Diseases, Vol. I, Protein Aggregation and Conformational Diseases
-
-
Cole, G.J.1
Liu, I.-H.2
-
11
-
-
0033602772
-
Identification of extracellular matrix ligands for the heparan sulfate proteoglycan agrin
-
Cotman, S.L., Halfter, W., and Cole, G.J. (1999) Identification of extracellular matrix ligands for the heparan sulfate proteoglycan agrin. Exp. Cell Res., 249, 54-64.
-
(1999)
Exp. Cell Res.
, vol.249
, pp. 54-64
-
-
Cotman, S.L.1
Halfter, W.2
Cole, G.J.3
-
12
-
-
0033953066
-
Agrin binds to β-amyloid (Aβ), accelerates Aβ fibril formation, and is localized to Aβ deposits in Alzheimer's disease brain
-
Cotman, S.L., Halfter, W., and Cole, G.J. (2000) Agrin binds to β-amyloid (Aβ), accelerates Aβ fibril formation, and is localized to Aβ deposits in Alzheimer's disease brain. Mol. Cell Neurosci., 15, 183-198.
-
(2000)
Mol. Cell Neurosci.
, vol.15
, pp. 183-198
-
-
Cotman, S.L.1
Halfter, W.2
Cole, G.J.3
-
13
-
-
0029591857
-
An amino-terminal extension is required for the secretion of chick agrin and its binding to extracellular matrix
-
Denzer, A.J., Gesemann, M., Schumacher, B., and Ruegg, M.A. (1995) An amino-terminal extension is required for the secretion of chick agrin and its binding to extracellular matrix. J. Cell Biol., 131, 1547-1560.
-
(1995)
J. Cell Biol.
, vol.131
, pp. 1547-1560
-
-
Denzer, A.J.1
Gesemann, M.2
Schumacher, B.3
Ruegg, M.A.4
-
14
-
-
0033065103
-
Agrin in Alzheimer's disease: Altered solubility and abnormal distribution within microvasculature and brain parenchyma
-
Donahue, J.E., Berzin, T.M., Rafii, M.S., Glass, D.J., Yancopoulos, G.D., Fallon, J.R., and Stopa, E.G. (1999) Agrin in Alzheimer's disease: altered solubility and abnormal distribution within microvasculature and brain parenchyma. Proc. Natl. Acad. Sci. U. S. A., 96, 6468-6472.
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 6468-6472
-
-
Donahue, J.E.1
Berzin, T.M.2
Rafii, M.S.3
Glass, D.J.4
Yancopoulos, G.D.5
Fallon, J.R.6
Stopa, E.G.7
-
15
-
-
0032573289
-
Effects of the mutations Ala30 to Pro and Ala53 to Thr on the physical and morphological properties of alpha-synuclein protein implicated in Parkinson's disease
-
El-Agnaf, O.M., Jakes, R., Curran, M.D., and Wallace, A. (1998a) Effects of the mutations Ala30 to Pro and Ala53 to Thr on the physical and morphological properties of alpha-synuclein protein implicated in Parkinson's disease. FEBS Lett., 440, 67-70.
-
(1998)
FEBS Lett.
, vol.440
, pp. 67-70
-
-
El-Agnaf, O.M.1
Jakes, R.2
Curran, M.D.3
Wallace, A.4
-
16
-
-
0032573597
-
Aggregates from mutant and wild-type α-synuclein proteins and NAC peptide induce apoptotic cell death in human neuroblastoma cells by formation of β-sheet and amyloid-like filaments
-
El-Agnaf, O.M.A., Jakes, R., Curran, M.D., Middleton, D., Ingenito, R., Bianchi, E., Pessi, A., Neill, D., and Wallace, A. (1998b) Aggregates from mutant and wild-type α-synuclein proteins and NAC peptide induce apoptotic cell death in human neuroblastoma cells by formation of β-sheet and amyloid-like filaments. FEBS Lett., 440, 71-75.
-
(1998)
FEBS Lett.
, vol.440
, pp. 71-75
-
-
El-Agnaf, O.M.A.1
Jakes, R.2
Curran, M.D.3
Middleton, D.4
Ingenito, R.5
Bianchi, E.6
Pessi, A.7
Neill, D.8
Wallace, A.9
-
17
-
-
0021207461
-
Alzheimer's disease and Downs's syndrome: Sharing a unique cerebrovascular amyloid fibril protein
-
Glenner, G.G. and Wong, C.W. (1984) Alzheimer's disease and Downs's syndrome: Sharing a unique cerebrovascular amyloid fibril protein. Biochem. Biophys. Res. Commun., 122, 1131-1135.
-
(1984)
Biochem. Biophys. Res. Commun.
, vol.122
, pp. 1131-1135
-
-
Glenner, G.G.1
Wong, C.W.2
-
18
-
-
0033771793
-
Is there a cause-and-effect relationship between alpha-synuclein fibrillization and Parkinson's disease?
-
Goldberg, M.S. and Lansbury, P.T. Jr. (2000) Is there a cause-and-effect relationship between alpha-synuclein fibrillization and Parkinson's disease? Nat. Cell Biol., 2, E115-E119.
-
(2000)
Nat. Cell Biol.
, vol.2
-
-
Goldberg, M.S.1
Lansbury Jr., P.T.2
-
19
-
-
0037073748
-
Golgi fragmentation occurs in the cells with prefibrillar α-synuclein aggregates and precedes the formation of fibrillar inclusion
-
Gosavi, N., Lee, H.-J., Lee, J.S., Patel, S., and Lee, S.-J. (2002) Golgi fragmentation occurs in the cells with prefibrillar α-synuclein aggregates and precedes the formation of fibrillar inclusion. J. Biol. Chem., 277, 48984-48992.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 48984-48992
-
-
Gosavi, N.1
Lee, H.-J.2
Lee, J.S.3
Patel, S.4
Lee, S.-J.5
-
20
-
-
0030902790
-
Distribution and substrate properties of agrin, a heparan sulfate proteoglycan of developing axonal pathways
-
Halfter, W., Schurer, B., Yip, J., Yip, L., Tsen, G., Lee, J.-A., and Cole, G.J. (1997) Distribution and substrate properties of agrin, a heparan sulfate proteoglycan of developing axonal pathways. J. Comp. Neurol., 383, 1-17.
-
(1997)
J. Comp. Neurol.
, vol.383
, pp. 1-17
-
-
Halfter, W.1
Schurer, B.2
Yip, J.3
Yip, L.4
Tsen, G.5
Lee, J.-A.6
Cole, G.J.7
-
21
-
-
0033570337
-
Protofibrillar intermediates of amyloid-β-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons
-
Hartley, D.M., Walsh, D.M., Ye, C.P., Diehl, T., Vasquez, S., Vassilev, P.M., Teplow, D.B., and Selkoe, D.J. (1999) Protofibrillar intermediates of amyloid-β-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons. J. Neurosci., 19, 8876-8884.
-
(1999)
J. Neurosci.
, vol.19
, pp. 8876-8884
-
-
Hartley, D.M.1
Walsh, D.M.2
Ye, C.P.3
Diehl, T.4
Vasquez, S.5
Vassilev, P.M.6
Teplow, D.B.7
Selkoe, D.J.8
-
22
-
-
0033043018
-
Interactions of neural glycosaminoglycans and proteoglycans with protein ligands: Assessment of selectivity, heterogeneity and the participation of core proteins in binding
-
39
-
Herndon, M.E., Stipp, C.S., and Lander, A.D. (1999) Interactions of neural glycosaminoglycans and proteoglycans with protein ligands: assessment of selectivity, heterogeneity and the participation of core proteins in binding. Glycobiology, 2, 143-155.39.
-
(1999)
Glycobiology
, vol.2
, pp. 143-155
-
-
Herndon, M.E.1
Stipp, C.S.2
Lander, A.D.3
-
23
-
-
0037177869
-
Not All perlecans are created equal
-
Knox, S., Merry, C., Stringer, S., Melrose, J., and Whitelock, J. (2002) Not All perlecans are created equal. J. Biol. Chem., 277, 14657-14665.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 14657-14665
-
-
Knox, S.1
Merry, C.2
Stringer, S.3
Melrose, J.4
Whitelock, J.5
-
24
-
-
0031990490
-
Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease
-
Kruger, R., Kuhn, W., Muller, T., Woitalla, D., Graeber, M., Kosel, S., Przuntek, H., Epplen, J.T., Schols, L., and Riess, O. (1998) Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease. Nat. Genet., 18, 106-108.
-
(1998)
Nat. Genet.
, vol.18
, pp. 106-108
-
-
Kruger, R.1
Kuhn, W.2
Muller, T.3
Woitalla, D.4
Graeber, M.5
Kosel, S.6
Przuntek, H.7
Epplen, J.T.8
Schols, L.9
Riess, O.10
-
25
-
-
11544279355
-
1-42 are potent central nervous system neurotoxins
-
and others
-
1-42 are potent central nervous system neurotoxins. Proc. Natl. Acad. Sci. U. S. A., 95, 6448-6453.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 6448-6453
-
-
Lambert, M.P.1
Barlow, A.K.2
Chromy, B.A.3
Edwards, C.4
Freed, R.5
Liosatos, M.6
Morgan, T.E.7
Rozovsky, I.8
Trommer, B.9
Viola, K.L.10
-
26
-
-
0037073747
-
Characterization of cytoplasmic α-synuclein aggregates. Fibril formation is tightly linked to the inclusion-forming process in cells
-
Lee, H.-J. and Lee, S.-J. (2002) Characterization of cytoplasmic α-synuclein aggregates. Fibril formation is tightly linked to the inclusion-forming process in cells. J. Biol. Chem., 277, 48976-48983.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 48976-48983
-
-
Lee, H.-J.1
Lee, S.-J.2
-
27
-
-
21344456506
-
Intravesicular localization and exocytosis of α-synuclein and its aggregates
-
Lee, H.-J., Patel, S., and Lee, S.J. (2005) Intravesicular localization and exocytosis of α-synuclein and its aggregates. J. Neurosci., 25, 6016-6024.
-
(2005)
J. Neurosci.
, vol.25
, pp. 6016-6024
-
-
Lee, H.-J.1
Patel, S.2
Lee, S.J.3
-
28
-
-
0027502784
-
Thioflavine T interaction with synthetic Alzheimer's disease beta-amyloid peptides: Detection of amyloid aggregation in solution
-
LeVine, H.D. (1993) Thioflavine T interaction with synthetic Alzheimer's disease beta-amyloid peptides: Detection of amyloid aggregation in solution. Protein Sci., 2, 404-410.
-
(1993)
Protein Sci.
, vol.2
, pp. 404-410
-
-
LeVine, H.D.1
-
29
-
-
0035949542
-
Effect of familial Parkinson's disease point mutations A30P and A53T on the structural properties, aggregation and fibrillation of human α-synuclein
-
Li, J., Uversky, V.N., and Fink, A.L. (2001) Effect of familial Parkinson's disease point mutations A30P and A53T on the structural properties, aggregation and fibrillation of human α-synuclein. Biochemistry, 40, 11604-11613.
-
(2001)
Biochemistry
, vol.40
, pp. 11604-11613
-
-
Li, J.1
Uversky, V.N.2
Fink, A.L.3
-
30
-
-
0036777533
-
Conformational behavior of human α-synuclein is modulated by familial Parkinson's disease point mutations A30P and A53T
-
Li, J., Uversky, V.N., and Fink, A.L. (2002) Conformational behavior of human α-synuclein is modulated by familial Parkinson's disease point mutations A30P and A53T. Neurotoxicology, 23, 553-567.
-
(2002)
Neurotoxicology
, vol.23
, pp. 553-567
-
-
Li, J.1
Uversky, V.N.2
Fink, A.L.3
-
31
-
-
0030717480
-
Amyloid-specific heparan sulfate from human liver and spleen
-
Lindahl, B. and Lindahl, U. (1997) Amyloid-specific heparan sulfate from human liver and spleen. J. Biol. Chem., 272, 26091-26094.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 26091-26094
-
-
Lindahl, B.1
Lindahl, U.2
-
32
-
-
0028895640
-
Structure of heparan sulphate from human brain, with special regard to Alzheimer's disease
-
Lindahl, B., Eriksson, L., and Lindahl, U. (1995) Structure of heparan sulphate from human brain, with special regard to Alzheimer's disease. Biochem. J., 306, 177-184.
-
(1995)
Biochem. J.
, vol.306
, pp. 177-184
-
-
Lindahl, B.1
Eriksson, L.2
Lindahl, U.3
-
33
-
-
0035117793
-
Immunohistochemical studies on proteoglycan expression in normal skin and chronic ulcers
-
Lundquist, K. and Schmidtchen, A. (2001) Immunohistochemical studies on proteoglycan expression in normal skin and chronic ulcers. Br. J. Dermatol., 144, 254-259.
-
(2001)
Br. J. Dermatol.
, vol.144
, pp. 254-259
-
-
Lundquist, K.1
Schmidtchen, A.2
-
34
-
-
0032006297
-
Heparan sulfate proteoglycan is associated with amyloid plaques and neuroanatomically targeted PrP pathology throughout the incubation period of scrapie-infected mice
-
McBride, P.A., Wilson, M.I., Eikelenboom, P., Tunstall, A., and Bruce, E.M. (1998) Heparan sulfate proteoglycan is associated with amyloid plaques and neuroanatomically targeted PrP pathology throughout the incubation period of scrapie-infected mice. Exp. Neurol., 149, 447-454.
-
(1998)
Exp. Neurol.
, vol.149
, pp. 447-454
-
-
McBride, P.A.1
Wilson, M.I.2
Eikelenboom, P.3
Tunstall, A.4
Bruce, E.M.5
-
35
-
-
0024212706
-
Circular-dichroism studies on two murine serum amyloid A proteins
-
McCubbin, W.D., Kay, C.M., Narindrasorasak, S., and Kisilevsky, R. (1988) Circular-dichroism studies on two murine serum amyloid A proteins. Biochem. J., 256, 775-783.
-
(1988)
Biochem. J.
, vol.256
, pp. 775-783
-
-
McCubbin, W.D.1
Kay, C.M.2
Narindrasorasak, S.3
Kisilevsky, R.4
-
36
-
-
0033458043
-
A sulfated proteoglycan aggregation factor mediates amyloid-β-peptide fibril formation and neurotoxicity
-
McLaurin, J., Franklin, T., Kuhns, W.J., and Fraser, P.E. (1999) A sulfated proteoglycan aggregation factor mediates amyloid-β-peptide fibril formation and neurotoxicity. Amyloid, 6, 233-243.
-
(1999)
Amyloid
, vol.6
, pp. 233-243
-
-
McLaurin, J.1
Franklin, T.2
Kuhns, W.J.3
Fraser, P.E.4
-
37
-
-
0024509805
-
Fluorometric determination of amyloid fibrils in vitro using the fluorescent dye, thioflavin T1
-
Naiki, H., Higuchi, K., Hosokawa, M., and Takeda, T. (1989) Fluorometric determination of amyloid fibrils in vitro using the fluorescent dye, thioflavin T1. Anal. Biochem., 177, 244-249.
-
(1989)
Anal. Biochem.
, vol.177
, pp. 244-249
-
-
Naiki, H.1
Higuchi, K.2
Hosokawa, M.3
Takeda, T.4
-
38
-
-
0033515471
-
Both familial Parkinson's disease mutations accelerate alpha-synuclein aggregation
-
and others
-
Narhi, L., Wood, S.J., Steavenson, S., Jiang, Y., Wu, G.M., Anafi, D., Kaufman, S.A., Martin, F., Sitney, K., Denis, P., and others. (1999) Both familial Parkinson's disease mutations accelerate alpha-synuclein aggregation. J. Biol. Chem., 274, 9843-9846.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 9843-9846
-
-
Narhi, L.1
Wood, S.J.2
Steavenson, S.3
Jiang, Y.4
Wu, G.M.5
Anafi, D.6
Kaufman, S.A.7
Martin, F.8
Sitney, K.9
Denis, P.10
-
39
-
-
0035918550
-
The effect of environmental factors on the kinetics of insulin fibril formation: Elucidation of the molecular mechanism
-
Nielsen, L., Khurana, R., Coats, A., Vyas, S., Frokjaer, S., Brange, J., Uversky, V.N., and Fink, A.L. (2001) The effect of environmental factors on the kinetics of insulin fibril formation: Elucidation of the molecular mechanism. Biochemistry, 40, 6036-6046.
-
(2001)
Biochemistry
, vol.40
, pp. 6036-6046
-
-
Nielsen, L.1
Khurana, R.2
Coats, A.3
Vyas, S.4
Frokjaer, S.5
Brange, J.6
Uversky, V.N.7
Fink, A.L.8
-
40
-
-
0032512871
-
Heparan sulfate proteoglycans recognize ghost Pick bodies
-
Odawara, T., Iseki, E., Li, F., Kosaka, K., and Ikeda, K. (1998) Heparan sulfate proteoglycans recognize ghost Pick bodies. Neurosci. Lett., 242, 120-122.
-
(1998)
Neurosci. Lett.
, vol.242
, pp. 120-122
-
-
Odawara, T.1
Iseki, E.2
Li, F.3
Kosaka, K.4
Ikeda, K.5
-
41
-
-
0026548720
-
Basic fibroblast growth factor binds to filamentous inclusions of neurodegenerative diseases
-
Perry, G., Richey, P., Siedlak, S.L., Galloway, P., Kawai, M., and Cras, P. (1992) Basic fibroblast growth factor binds to filamentous inclusions of neurodegenerative diseases. Brain Res., 579, 350-352.
-
(1992)
Brain Res.
, vol.579
, pp. 350-352
-
-
Perry, G.1
Richey, P.2
Siedlak, S.L.3
Galloway, P.4
Kawai, M.5
Cras, P.6
-
42
-
-
0025992417
-
In vitro aging of β-amyloid protein causes peptide aggregation and neurotoxicity
-
Pike, C.J., Walencewicz, A.J., Glabe, C.G., and Cotman, C.W. (1991) In vitro aging of β-amyloid protein causes peptide aggregation and neurotoxicity. Brain Res., 563, 311-314.
-
(1991)
Brain Res.
, vol.563
, pp. 311-314
-
-
Pike, C.J.1
Walencewicz, A.J.2
Glabe, C.G.3
Cotman, C.W.4
-
43
-
-
0030744876
-
Mutation in the alpha-synuclein gene identified in families with Parkinson's disease
-
and others
-
Polymeropoulos, M.H., Lavedan, C., Leroy, E., Ide, S.E., Dehejia, A., Dutra, A., Pike, B., Root, H., Rubenstein, J., Boyer, R., and others. (1997) Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. Science, 276, 2045-2047.
-
(1997)
Science
, vol.276
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
Ide, S.E.4
Dehejia, A.5
Dutra, A.6
Pike, B.7
Root, H.8
Rubenstein, J.9
Boyer, R.10
-
44
-
-
0031851412
-
Heparan sulphate proteoglycan expression in human primary liver tumours
-
Roskams, T., de Vos, R., David, G., Van Damme, B., and Desmet, V. (1999) Heparan sulphate proteoglycan expression in human primary liver tumours. J. Pathol., 185, 290-297.
-
(1999)
J. Pathol.
, vol.185
, pp. 290-297
-
-
Roskams, T.1
de Vos, R.2
David, G.3
Van Damme, B.4
Desmet, V.5
-
45
-
-
0028339775
-
Fine structure of heparan sulfate regulates syndecan-1 function and cell behavior
-
Sanderson, R.D., Turnbull, J.E., Gallagher, J.T., and Lander, A.D. (1994) Fine structure of heparan sulfate regulates syndecan-1 function and cell behavior. J. Biol. Chem., 269, 13100-13106.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 13100-13106
-
-
Sanderson, R.D.1
Turnbull, J.E.2
Gallagher, J.T.3
Lander, A.D.4
-
46
-
-
0142059961
-
Heparan sulfate regulates amyloid precursor protein processing by BACE1, the Alzheimer's beta-secretase
-
Scholefield, Z., Yates, E.A., Wayne, G., Amour, A., McDowell, W., and Turnbull, J.E. (2003) Heparan sulfate regulates amyloid precursor protein processing by BACE1, the Alzheimer's beta-secretase. J. Cell Biol., 163, 97-107.
-
(2003)
J. Cell Biol.
, vol.163
, pp. 97-107
-
-
Scholefield, Z.1
Yates, E.A.2
Wayne, G.3
Amour, A.4
McDowell, W.5
Turnbull, J.E.6
-
47
-
-
0034703336
-
TorsinA accumulation in Lewy bodies in sporadic Parkinson's disease
-
Shashidharan, P., Good, P.F., Hsu, A., Perl, D.P., Brin, M.F., and Olanow, C.W. (2000) TorsinA accumulation in Lewy bodies in sporadic Parkinson's disease. Brain Res., 877, 379-381.
-
(2000)
Brain Res.
, vol.877
, pp. 379-381
-
-
Shashidharan, P.1
Good, P.F.2
Hsu, A.3
Perl, D.P.4
Brin, M.F.5
Olanow, C.W.6
-
48
-
-
0023128689
-
Sulfated glycosaminoglycans: A common constituent of all amyloids?
-
Snow, A.D., Willmer, J., and Kisilevsky, R. (1987) Sulfated glycosaminoglycans: A common constituent of all amyloids? Lab. Invest., 56, 120-123.
-
(1987)
Lab. Invest.
, vol.56
, pp. 120-123
-
-
Snow, A.D.1
Willmer, J.2
Kisilevsky, R.3
-
49
-
-
0024539012
-
Sulfated glycosaminoglycans in amyloid plaques of prion diseases
-
Snow, A.D., Kisilevsky, R., Willmer, J., Prusiner, S.B., and DeArmond, S.J. (1989) Sulfated glycosaminoglycans in amyloid plaques of prion diseases. Acta Neuropathol. (Berl), 77, 337-342.
-
(1989)
Acta Neuropathol. (Berl.)
, vol.77
, pp. 337-342
-
-
Snow, A.D.1
Kisilevsky, R.2
Willmer, J.3
Prusiner, S.B.4
DeArmond, S.J.5
-
50
-
-
0025243737
-
Immunolocalization of heparan sulfate proteoglycans to the prion protein amyloid plaques of Gerstmann-Straussler syndrome, Creutzfeld-Jakob disease and scrapie
-
Snow, A.D., Wight, T.N., Nochlin, D., Koike, Y., Kimata, K., DeArmond, S.J., and Prusiner, S.B. (1990) Immunolocalization of heparan sulfate proteoglycans to the prion protein amyloid plaques of Gerstmann-Straussler syndrome, Creutzfeld-Jakob disease and scrapie. Lab. Invest., 63, 601-611.
-
(1990)
Lab. Invest.
, vol.63
, pp. 601-611
-
-
Snow, A.D.1
Wight, T.N.2
Nochlin, D.3
Koike, Y.4
Kimata, K.5
DeArmond, S.J.6
Prusiner, S.B.7
-
51
-
-
0025913954
-
A temporal and ultrastructural relationship between heparan sulfate proteoglycans and AA amyloid in experimental amyloidosis
-
Snow, A.D., Bramson, R., Mar., H., Wight, T.N., and Kisilevsky, R. (1991) A temporal and ultrastructural relationship between heparan sulfate proteoglycans and AA amyloid in experimental amyloidosis. J. Histochem. Cytochem., 39, 1321-1330.
-
(1991)
J. Histochem. Cytochem.
, vol.39
, pp. 1321-1330
-
-
Snow, A.D.1
Bramson, R.2
Mar, H.3
Wight, T.N.4
Kisilevsky, R.5
-
52
-
-
0028082136
-
An important role of heparan sulfate proteoglycan (Perlecan) in a model system for the deposition and persistence of fibrillar A beta-amyloid in rat brain
-
Snow, A.D., Sekiguchi, R., Nochlin, D., Fraser, P., Kimata, K., Mizutani, A., Arai, M., Schreier, W.A., and Morgan, D.G. (1994) An important role of heparan sulfate proteoglycan (Perlecan) in a model system for the deposition and persistence of fibrillar A beta-amyloid in rat brain. Neuron, 12, 219-234.
-
(1994)
Neuron
, vol.12
, pp. 219-234
-
-
Snow, A.D.1
Sekiguchi, R.2
Nochlin, D.3
Fraser, P.4
Kimata, K.5
Mizutani, A.6
Arai, M.7
Schreier, W.A.8
Morgan, D.G.9
-
53
-
-
0037264120
-
Unfolding the role of protein misfolding in neurodegenerative diseases
-
Soto, C. (2003) Unfolding the role of protein misfolding in neurodegenerative diseases. Nat. Rev. Neurosci., 4, 49-60.
-
(2003)
Nat. Rev. Neurosci.
, vol.4
, pp. 49-60
-
-
Soto, C.1
-
54
-
-
0030882856
-
Alpha-synuclein in Lewy bodies
-
Spillantini, M.G., Schmidt, M.L., Lee, V.M., Trojanowski, J.Q., Jakes, R., and Goedert, M. (1997) Alpha-synuclein in Lewy bodies. Nature, 388, 839-840.
-
(1997)
Nature
, vol.388
, pp. 839-840
-
-
Spillantini, M.G.1
Schmidt, M.L.2
Lee, V.M.3
Trojanowski, J.Q.4
Jakes, R.5
Goedert, M.6
-
55
-
-
0027407565
-
Apolipoprotein E: High-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease
-
Strittmatter, W.J., Saunders, A.M., Schmechel, D., Pericak-Vance, M., Enghild, J., Salvesen, G.S., and Roses, A.D. (1993) Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc. Natl. Acad. Sci. U. S. A., 90, 1977-1981.
-
(1993)
Proc. Natl. Acad. Sci. U. S. A.
, vol.90
, pp. 1977-1981
-
-
Strittmatter, W.J.1
Saunders, A.M.2
Schmechel, D.3
Pericak-Vance, M.4
Enghild, J.5
Salvesen, G.S.6
Roses, A.D.7
-
56
-
-
0026468915
-
Localization of heparan sulfate glycosaminoglycan and proteoglycan core protein in aged brain and Alzheimer's disease
-
Su, J.H., Cummings, B.H., and Cotman, C.W. (1992) Localization of heparan sulfate glycosaminoglycan and proteoglycan core protein in aged brain and Alzheimer's disease. Neuroscience, 51, 801-813.
-
(1992)
Neuroscience
, vol.51
, pp. 801-813
-
-
Su, J.H.1
Cummings, B.H.2
Cotman, C.W.3
-
57
-
-
0028322017
-
An increased percentage of long beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants
-
Suzuki, N., Cheung, T.T., Cai, X.D., Odaka, A., Otvos, L. Jr., Eckman, C., Golde, T.E., and Younkin, S.G. (1994) An increased percentage of long beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants. Science, 264, 1136-1140.
-
(1994)
Science
, vol.264
, pp. 1136-1140
-
-
Suzuki, N.1
Cheung, T.T.2
Cai, X.D.3
Odaka, A.4
Otvos Jr., L.5
Eckman, C.6
Golde, T.E.7
Younkin, S.G.8
-
58
-
-
0023109592
-
Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus
-
Tanzi, R.E., Gusella, J.F., Watkins, P.C., Bruns, G.A., St George-Hyslop, P., Van Keuren, M.L., Patterson, D., Pagan, S., Kurnit, D.M., and Neve, R.L. (1987) Amyloid beta protein gene: CDNA, mRNA distribution, and genetic linkage near the Alzheimer locus. Science, 235, 880-884.
-
(1987)
Science
, vol.235
, pp. 880-884
-
-
Tanzi, R.E.1
Gusella, J.F.2
Watkins, P.C.3
Bruns, G.A.4
St George-Hyslop, P.5
Van Keuren, M.L.6
Patterson, D.7
Pagan, S.8
Kurnit, D.M.9
Neve, R.L.10
-
59
-
-
0028813382
-
Agrin is a heparan sulfate proteoglycan
-
Tsen, G., Halfter, W., Kroger, S., and Cole, G.J. (1995) Agrin is a heparan sulfate proteoglycan. J. Biol. Chem., 270, 3392-3399.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 3392-3399
-
-
Tsen, G.1
Halfter, W.2
Kroger, S.3
Cole, G.J.4
-
60
-
-
0141677840
-
A protein-chameleon: Conformationaol plasticity of α-synuclein, a disordered protein involved in neurodegenerative disorders
-
Uversky, V.N. (2003) A protein-chameleon: Conformationaol plasticity of α-synuclein, a disordered protein involved in neurodegenerative disorders. J. Biomol. Struct. Dyn., 21, 211-234.
-
(2003)
J. Biomol. Struct. Dyn.
, vol.21
, pp. 211-234
-
-
Uversky, V.N.1
-
61
-
-
5444248216
-
Biophysical properties of human α-synuclein and its role in Parkinson's disease
-
Pandalai, S.G. (ed.), Transworld Research Network, Kerala, India
-
Uversky, V.N. and Fink, A.L. (2002) Biophysical properties of human α-synuclein and its role in Parkinson's disease. In Pandalai, S.G. (ed.), Recent Research Developments in Proteins. Transworld Research Network, Kerala, India, Vol. 1, pp. 153-186.
-
(2002)
Recent Research Developments in Proteins
, vol.1
, pp. 153-186
-
-
Uversky, V.N.1
Fink, A.L.2
-
62
-
-
4444316508
-
Conformational constraints for the amyloid fibrillation: The importance of being unfolded
-
Uversky, V.N. and Fink, A.L. (2004) Conformational constraints for the amyloid fibrillation: The importance of being unfolded. Biochim. Biophys. Acta, 43, 5575-5582.
-
(2004)
Biochim. Biophys. Acta
, vol.43
, pp. 5575-5582
-
-
Uversky, V.N.1
Fink, A.L.2
-
63
-
-
28444471550
-
Folding and misfolding of α-synuclein
-
(in press) Kahle, P. and Haass, C. (eds), Landes Bioscience, Georgetown, Washington, DC
-
Uversky, V.N. and Fink, A.L. (in press) Folding and misfolding of α-synuclein. In Kahle, P. and Haass, C. (eds), Molecular Mechanisms in Parkinson's Disease. Landes Bioscience, Georgetown, Washington, DC.
-
Molecular Mechanisms in Parkinson's Disease
-
-
Uversky, V.N.1
Fink, A.L.2
-
64
-
-
0035815664
-
Evidence for a partially folded intermediate in α-synuclein fibril formation
-
Uversky, V.N., Li, J., and Fink, A.L. (2001) Evidence for a partially folded intermediate in α-synuclein fibril formation. J. Biol. Chem., 276, 10737-10744.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 10737-10744
-
-
Uversky, V.N.1
Li, J.2
Fink, A.L.3
-
65
-
-
0035157875
-
Heparan sulfate proteoglycan expression in cerebrovascular amyloid β deposits in Alzheimer's disease and hereditary cerebral hemorrhage with amyloidosis (Dutch) brains
-
van Horssen, J., Otte-Holler, I., David, G., Maat-Schieman, M.L.C., van den Heuvel, L.P.W.J., Wesseling, P., de Waal, R.M.W., and Verbeek, M.M. (2001) Heparan sulfate proteoglycan expression in cerebrovascular amyloid β deposits in Alzheimer's disease and hereditary cerebral hemorrhage with amyloidosis (Dutch) brains. Acta Neuropathol. (Berl), 102, 604-614.
-
(2001)
Acta Neuropathol. (Berl.)
, vol.102
, pp. 604-614
-
-
van Horssen, J.1
Otte-Holler, I.2
David, G.3
Maat-Schieman, M.L.C.4
van den Heuvel, L.P.W.J.5
Wesseling, P.6
de Waal, R.M.W.7
Verbeek, M.M.8
-
66
-
-
16644393251
-
Absence of heparan sulfate proteoglycans in Lewy bodies and Lewy neurites in Parkinson disease brains
-
van Horssen, J., de Vos, R.A., Steur, E.N., David, G., Wesseling, P., de Waal, R.M., and Verbeek, M.M. (2004) Absence of heparan sulfate proteoglycans in Lewy bodies and Lewy neurites in Parkinson disease brains. J. Alzheimers Dis., 6, 469-474.
-
(2004)
J. Alzheimers Dis.
, vol.6
, pp. 469-474
-
-
van Horssen, J.1
de Vos, R.A.2
Steur, E.N.3
David, G.4
Wesseling, P.5
de Waal, R.M.6
Verbeek, M.M.7
-
67
-
-
0345008875
-
Agrin is a major heparan sulfate proteoglycan accumulating in Alzheimer's disease brain
-
Verbeek, M.M., Otte-Holler, I., van den Born, J., van den Heuvel, L.P., David, G., Wesseling, P., and de Waal, R.M. (1999) Agrin is a major heparan sulfate proteoglycan accumulating in Alzheimer's disease brain. Am. J. Pathol., 155, 2115-2125.
-
(1999)
Am. J. Pathol.
, vol.155
, pp. 2115-2125
-
-
Verbeek, M.M.1
Otte-Holler, I.2
van den Born, J.3
van den Heuvel, L.P.4
David, G.5
Wesseling, P.6
de Waal, R.M.7
-
68
-
-
0035800097
-
Vesicle permeabilization by protofibrillar alpha-synuclein: Implications for the pathogenesis and treatment of Parkinson's disease
-
Volles, M.J., Lee, S.J., Rochet, J.C., Shtilerman, M.D., Ding, T.T., Kessler, J.C., and Lansbury, P.T. Jr. (2001) Vesicle permeabilization by protofibrillar alpha-synuclein: Implications for the pathogenesis and treatment of Parkinson's disease. Biochemistry, 40, 7812-7819.
-
(2001)
Biochemistry
, vol.40
, pp. 7812-7819
-
-
Volles, M.J.1
Lee, S.J.2
Rochet, J.C.3
Shtilerman, M.D.4
Ding, T.T.5
Kessler, J.C.6
Lansbury Jr., P.T.7
-
69
-
-
0031715399
-
Accumulation of alpha-synuclein/NACP is a cytopathological feature common to Lewy body disease and multiple system atrophy
-
Wakabayashi, K., Hayashi, S., Kakita, A., Yamada, M., Toyoshima, Y., Yoshimoto, M., and Takahashi, H. (1997) Accumulation of alpha-synuclein/ NACP is a cytopathological feature common to Lewy body disease and multiple system atrophy. Acta Neuropathol. (Berl), 96, 445-452.
-
(1997)
Acta Neuropathol. (Berl.)
, vol.96
, pp. 445-452
-
-
Wakabayashi, K.1
Hayashi, S.2
Kakita, A.3
Yamada, M.4
Toyoshima, Y.5
Yoshimoto, M.6
Takahashi, H.7
-
70
-
-
0041529510
-
Agrin is a chimeric proteoglycan with the attachment sites for heparan sulfate/chondroitin sulfate located in two multiple serine-glycine clusters
-
Winzen, U., Cole, G.J., and Halfter, W. (2003) Agrin is a chimeric proteoglycan with the attachment sites for heparan sulfate/chondroitin sulfate located in two multiple serine-glycine clusters. J. Biol. Chem., 278, 30106-20114.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 20114-30106
-
-
Winzen, U.1
Cole, G.J.2
Halfter, W.3
-
71
-
-
0033538541
-
Alpha-synuclein fibrillogenesis is nucleation-dependent. Implications for the pathogenesis of Parkinson's disease
-
Wood, S.J., Wypych, J., Steavenson, S., Louis, J.C., Citron, M., and Biere, A.L. (1999) Alpha-synuclein fibrillogenesis is nucleation-dependent. Implications for the pathogenesis of Parkinson's disease. J. Biol. Chem., 274, 19509-19512.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 19509-19512
-
-
Wood, S.J.1
Wypych, J.2
Steavenson, S.3
Louis, J.C.4
Citron, M.5
Biere, A.L.6
-
72
-
-
0026688125
-
Localization of the basement membrane heparan sulfate proteoglycan in islet amyloid deposits in type II diabetes mellitus
-
Young, I.D., Ailles, L., Narindrasorasak, S., Tan, R., and Kisilevsky, R. (1992) Localization of the basement membrane heparan sulfate proteoglycan in islet amyloid deposits in type II diabetes mellitus. Arch. Pathol. Lab. Med., 116, 951-954.
-
(1992)
Arch. Pathol. Lab. Med.
, vol.116
, pp. 951-954
-
-
Young, I.D.1
Ailles, L.2
Narindrasorasak, S.3
Tan, R.4
Kisilevsky, R.5
-
73
-
-
0026696170
-
Characterization of proteoglycans in Alzheimer's disease fibroblasts
-
Zebrower, M., Beeber, C., and Kieras, F.J. (1992) Characterization of proteoglycans in Alzheimer's disease fibroblasts. Biochem. Biophys. Res. Commun., 184, 1293-1300.
-
(1992)
Biochem. Biophys. Res. Commun.
, vol.184
, pp. 1293-1300
-
-
Zebrower, M.1
Beeber, C.2
Kieras, F.J.3
-
74
-
-
0034595728
-
Overexpression of human α-synuclein causes dopamine neuron death in rat primary culture and immortalized mesencephalon-derived cells
-
Zhou, W., Hurlbert, M.S., Schaack, J., Prasad, K.N., and Freed, C.R. (2000) Overexpression of human α-synuclein causes dopamine neuron death in rat primary culture and immortalized mesencephalon-derived cells. Brain Res., 866, 33-43.
-
(2000)
Brain Res.
, vol.866
, pp. 33-43
-
-
Zhou, W.1
Hurlbert, M.S.2
Schaack, J.3
Prasad, K.N.4
Freed, C.R.5
-
75
-
-
0036468957
-
Over-expression of human α-synuclein causes dopamine neuron death in primary human mesencephalic culture
-
Zhou, W., Schaack, J., Zawada, W.M., and Freed, C.R. (2002) Over-expression of human α-synuclein causes dopamine neuron death in primary human mesencephalic culture. Brain Res., 926, 42-50.
-
(2002)
Brain Res.
, vol.926
, pp. 42-50
-
-
Zhou, W.1
Schaack, J.2
Zawada, W.M.3
Freed, C.R.4
|