Lipopolysaccharide animal models for parkinson's disease

Parkinson's Disease

Volumn , Issue , 2011, Pages

  Bing, Guoying ^a   Liu, Mei ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MINOCYCLINE; NALOXONE; NITRIC OXIDE SYNTHASE; OXIDOPAMINE; PIOGLITAZONE; TUMOR NECROSIS FACTOR ALPHA;

CELL CULTURE; CELL SURVIVAL; CORPUS STRIATUM; DOPAMINERGIC NERVE CELL; GLOBUS PALLIDUS; IN VITRO STUDY; IN VIVO STUDY; MACROGLIA; NERVE DEGENERATION; NEUROPROTECTION; NEUROTOXICITY; PARKINSON DISEASE; PATHOGENESIS; PRIORITY JOURNAL; REVIEW; SUBSTANTIA NIGRA;

EID: 79959229744     PISSN: None     EISSN: 20420080     Source Type: Journal    
DOI: 10.4061/2011/327089     Document Type: Review

References (70)

1. Kim Y. S., Joh T. H., Microglia, major player in the brain inflammation: their roles in the pathogenesis of Parkinson's disease Experimental and Molecular Medicine 2006 38 4 333 347
2. Block M. L., Zecca L., Hong J. S., Microglia-mediated neurotoxicity: uncovering the molecular mechanisms Nature Reviews Neuroscience 2007 8 1 57 69 (Pubitemid 46011999)
3. Nimmerjahn A., Kirchhoff F., Helmchen F., Neuroscience: resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo Science 2005 308 5726 1314 1318 (Pubitemid 40746128)
4. Davalos D., Grutzendler J., Yang G., Kim J. V., Zuo YI., Jung S., Littman D. R., Dustin M. L., Gan W. B., ATP mediates rapid microglial response to local brain injury in vivo Nature Neuroscience 2005 8 6 752 758 (Pubitemid 43085841)
5. Cho B. P., Song D. Y., Sugama S., Shin D. H., Shimizu Y., Kim S. S., Kim Y. S., Joh T. H., Pathological dynamics of activated microglia following medial forebrain bundle transection Glia 2006 53 1 92 102 (Pubitemid 43076216)
6. Streit W. J., Microglia as neuroprotective, immunocompetent cells of the CNS Glia 2002 40 2 133 139 (Pubitemid 35337371)
7. Banati R. B., Daniel S. E., Blunt S. B., Glial pathology but absence of apoptotic nigral neurons in long-standing Parkinson's disease Movement Disorders 1998 13 2 221 227 (Pubitemid 28127795)
8. Langston J. W., Forno L. S., Tetrud J., Reeves A. G., Kaplan J. A., Karluk D., Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure Annals of Neurology 1999 46 4 598 605 (Pubitemid 29466438)
9. Orr C. F., Rowe D. B., Mizuno Y., Mori H., Halliday G. M., A possible role for humoral immunity in the pathogenesis of Parkinson's disease Brain 2005 128 11 2665 2674 (Pubitemid 41552950)
10. Block M. L., Hong J. S., Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism Progress in Neurobiology 2005 76 2 77 98 (Pubitemid 41242883)
11. Streit W. J., Walter S. A., Pennell N. A., Reactive microgliosis Progress in Neurobiology 1999 57 6 563 581 (Pubitemid 29148415)
12. McGeer P. L., Itagaki S., Akiyama H., McGeer E. G., Rate of cell death in parkinsonism indicates active neuropathological process Annals of Neurology 1988 24 4 574 576
13. McGeer P. L., Itagaki S., Boyes B. E., McGeer E. G., Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains Neurology 1988 38 8 1285 1291
14. Imamura K., Hishikawa N., Sawada M., Nagatsu T., Yoshida M., Hashizume Y., Distribution of major histocompatibility complex class II-positive microglia and cytokine profile of Parkinson's disease brains Acta Neuropathologica 2003 106 6 518 526 (Pubitemid 37441607)
15. Bing G., Lu X., Zheng N. A., Jin L., Qi Y., Kim H.-C., Microglia mediated dopaminergic cell death in the substantia nigra: a new animal model for Parkinson's disease Neuroscience Abstracts 1998 24 44
16. Castao A., Herrera A. J., Cano J., Machado A., Lipopolysaccharide intranigral injection induces inflammatory reaction and damage in nigrostriatal dopaminergic system Journal of Neurochemistry 1998 70 4 1584 1592 (Pubitemid 28136972)
17. Zhang J., Stanton D. M., Nguyen X. V., Liu M., Zhang Z., Gash D., Bing G., Intrapallidal lipopolysaccharide injection increases iron and ferritin levels in glia of the rat substantia nigra and induces locomotor deficits Neuroscience 2005 135 3 829 838 (Pubitemid 41407745)
18. Qin L., Wu X., Block M. L., Liu Y., Breese G. R., Hong J. S., Knapp D. J., Crews F. T., Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration Glia 2007 55 5 453 462 (Pubitemid 46383175)
19. Choi D. Y., Liu M., Hunter R. L., Cass W. A., Pandya J. D., Sullivan P. G., Shin E. J., Kim H. C., Gash D. M., Bing G., Striatal neuroinflammation promotes parkinsonism in rats PLoS One 2009 4 5
20. Schletter J., Heine H., Ulmer A. J., Rietschel E. T., Molecular mechanisms of endotoxin activity Archives of Microbiology 1995 164 6 383 389 (Pubitemid 26018509)
21. Nedreb T., Reed R. K., Different serotypes of endotoxin (lipopolysaccharide) cause different increases in albumin extravasation in rats Shock 2002 18 2 138 141
22. Ulevitch R. J., Tobias P. S., Recognition of Gram-negative bacteria and endotoxin by the innate immune system Current Opinion in Immunology 1999 11 1 19 22 (Pubitemid 29082331)
23. Takeda K., Kaisho T., Akira S., Toll-like receptors Annual Review of Immunology 2003 21 335 376 (Pubitemid 37174535)
24. Janeway C. A. Jr., Medzhitov R., Innate immune recognition Annual Review of Immunology 2002 20 197 216 (Pubitemid 34293424)
25. Lacroix S., Feinstein D., Rivest S., The bacterial endotoxin lipopolysaccharide has the ability to target the brain in upregulating its membrane CD14 receptor within specific cellular populations Brain Pathology 1998 8 4 625 640 (Pubitemid 28460922)
26. Lehnardt S., Massillon L., Follett P., Jensen F. E., Ratan R., Rosenberg P. A., Volpe J. J., Vartanian T., Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathway Proceedings of the National Academy of Sciences of the United States of America 2003 100 14 8514 8519 (Pubitemid 36842576)
27. Hoshino K., Takeuchi O., Kawai T., Sanjo H., Ogawa T., Takeda Y., Takeda K., Akira S., Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide evidence for TLR4 as the Lps gene product Journal of Immunology 1999 162 7 3749 3752 (Pubitemid 29314747)
28. Niehaus I., Lange J. H., Endotoxin: is it an environmental factor in the cause of Parkinson's disease? Occupational and Environmental Medicine 2003 60 5 378 (Pubitemid 36532497)
29. Stewart I., Schluter P. J., Shaw G. R., Cyanobacterial lipopolysaccharides and human healtha review Environmental Health 2006 5, article 7
30. da Silva A. M. T., Kaulbach H. C., Chuidian F. S., Lambert D. R., Suffredini A. F., Danner R. L., Brief report: shock and multiple-organ dysfunction after self-administration of salmonella endotoxin The New England Journal of Medicine 1993 328 20 1457 1461 (Pubitemid 23143848)
31. Bronstein D. M., Perez-Otano I., Sun V., Mullis Sawin S. B., Chan J., Wu G. C., Hudson P. M., Kong L. Y., Hong J. S., McMillian M. K., Glia-dependent neurotoxicity and neuroprotection in mesencephalic cultures Brain Research 1995 704 1 112 116
32. Liu B., Du L., Hong J. S., Naloxone protects rat dopaminergic neurons against inflammatory damage through inhibition of microglia activation and superoxide generation Journal of Pharmacology and Experimental Therapeutics 2000 293 2 607 617 (Pubitemid 30244114)
33. Xing B., Xin T., Hunter R. L., Bing G., Pioglitazone inhibition of lipopolysaccharide-induced nitric oxide synthase is associated with altered activity of p38 MAP kinase and PI3K/ Akt Journal of Neuroinflammation 2008 5, article 4
34. Qin L., Liu Y., Wang T., Wei S. J., Block M. L., Wilson B., Liu B., Hong J. S., NADPH oxidase mediates lipopolysaccharide-induced neurotoxicity and proinflammatory gene expression in activated microglia Journal of Biological Chemistry 2004 279 2 1415 1421 (Pubitemid 38082669)
35. Lee S. C., Liu W., Dickson D. W., Brosnan C. F., Berman J. W., Cytokine production by human fetal microglia and astrocytes: differential induction by lipopolysaccharide and IL-1 Journal of Immunology 1993 150 7 2659 2667 (Pubitemid 23127515)
36. Chao C. C., Hu S., Molitor T. W., Shaskan E. G., Peterson P. K., Activated microglia mediate neuronal cell injury via a nitric oxide mechanism Journal of Immunology 1992 149 8 2736 2741
37. Herrera A. J., Castao A., Venero J. L., Cano J., Machado A., The single intranigral injection of LPS as a new model for studying the selective effects of inflammatory reactions on dopaminergic system Neurobiology of Disease 2000 7 4 429 447
38. Lu X., Bing G., Hagg T., Naloxone prevents microglia-induced degeneration of dopaminergic substantia nigra neurons in adult rats Neuroscience 2000 97 2 285 291 (Pubitemid 30224766)
39. Hernndez-Romero M. D. C., Argelles S., Villarn R. F., De Pablos R. M., Delgado-Corts M. J., Santiago M., Herrera A. J., Cano J., Machado A., Simvastatin prevents the inflammatory process and the dopaminergic degeneration induced by the intranigral injection of lipopolysaccharide Journal of Neurochemistry 2008 105 2 445 459 (Pubitemid 351490015)
40. Arimoto T., Choi D. Y., Lu X., Liu M., Nguyen X. V., Zheng N., Stewart C. A., Kim H. C., Bing G., Interleukin-10 protects against inflammation-mediated degeneration of dopaminergic neurons in substantia nigra Neurobiology of Aging 2007 28 6 894 906 (Pubitemid 46589742)
41. Hsieh P. F., Chia L. G., Ni D. R., Cheng L. J., Ho Y. P., Tzeng S. F., Chang M. H., Hong J. S., Behavior, neurochemistry and histology after intranigral lipopolysaccharide injection NeuroReport 2002 13 3 277 280 (Pubitemid 34183566)
42. Choi D. Y., Zhang J., Bing G., Aging enhances the neuroinflammatory response and -synuclein nitration in rats Neurobiology of Aging 2010 31 9 1649 1653
43. Zhang W., Wang T., Pei Z., Miller D. S., Wu X., Block M. L., Wilson B., Zhang W., Zhou Y., Hong J. S., Zhang J., Aggregated -synuclein activates microglia: a process leading to disease progression in Parkinson's disease FASEB Journal 2005 19 6 533 542 (Pubitemid 40471244)
44. Hunter R. L., Cheng B., Choi D. Y., Liu M., Liu S., Cass W. A., Bing G., Intrastriatal lipopolysaccharide injection induces Parkinsonism in C57/B6 mice Journal of Neuroscience Research 2009 87 8 1913 1921
45. Hunter R. L., Dragicevic N., Seifert K., Choi D. Y., Liu M., Kim H. C., Cass W. A., Sullivan P. G., Bing G., Inflammation induces mitochondrial dysfunction and dopaminergic neurodegeneration in the nigrostriatal system Journal of Neurochemistry 2007 100 5 1375 1386
46. Hunter R. L., Choi D. Y., Kincer J. F., Cass W. A., Bing G., Gash D. M., Fenbendazole treatment may influence lipopolysaccharide effects in rat brain Comparative Medicine 2007 57 5 487 492 (Pubitemid 351773343)
47. Bickel U., Grave B., Kang Y. S., Del Rey A., Voigt K., No increase in blood-brain barrier permeability after intraperitoneal injection of endotoxin in the rat Journal of Neuroimmunology 1998 85 2 131 136 (Pubitemid 28313497)
48. Pan W., Kastin A. J., TNF transport across the blood-brain barrier is abolished in receptor knockout mice Experimental Neurology 2002 174 2 193 200 (Pubitemid 34293449)
49. Banks W. A., Blood-brain barrier transport of cytokines: a mechanism for neuropathology Current Pharmaceutical Design 2005 11 8 973 984 (Pubitemid 40331299)
50. Byler S. L., Boehm G. W., Karp J. D., Kohman R. A., Tarr A. J., Schallert T., Barth T. M., Systemic lipopolysaccharide plus MPTP as a model of dopamine loss and gait instability in C57Bl/6J mice Behavioural Brain Research 2009 198 2 434 439
51. McGeer P. L., Schwab C., Parent A., Doudet D., Presence of reactive microglia in monkey substantia nigra years after 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine administration Annals of Neurology 2003 54 5 599 604 (Pubitemid 37346066)
52. Ouchi Y., Yoshikawa E., Sekine Y., Futatsubashi M., Kanno T., Ogusu T., Torizuka T., Microglial activation and dopamine terminal loss in early Parkinson's disease Annals of Neurology 2005 57 2 168 175 (Pubitemid 40179853)
53. Liu B., Jiang J. W., Wilson B. C., Du L., Yang S. N., Wang J. Y., Wu G. C., Cao X. D., Hong J. S., Systemic infusion of naloxone reduces degeneration of rat substantia nigral dopaminergic neurons induced by intranigral injection of lipopolysaccharide Journal of Pharmacology and Experimental Therapeutics 2000 295 1 125 132
54. Qian L., Block M. L., Wei S. J., Lin C. F., Reece J., Pang H., Wilson B., Hong J. S., Flood P. M., Interleukin-10 protects lipopolysaccharide-induced neurotoxicity in primary midbrain cultures by inhibiting the function of NADPH oxidase Journal of Pharmacology and Experimental Therapeutics 2006 319 1 44 52 (Pubitemid 44455109)
55. Hunter R. L., Choi D. Y., Ross S. A., Bing G., Protective properties afforded by pioglitazone against intrastriatal LPS in Sprague-Dawley rats Neuroscience Letters 2008 432 3 198 201
56. Xing B., Liu M., Bing G., Neuroprotection with pioglitazone against LPS insult on dopaminergic neurons may be associated with its inhibition of NF- B and JNK activation and suppression of COX-2 activity Journal of Neuroimmunology 2007 192 1-2 89 98 (Pubitemid 350213119)
57. Toms-Camardiel M., Rite I., Herrera A. J., De Pablos R. M., Cano J., Machado A., Venero J. L., Minocycline reduces the lipopolysaccharide-induced inflammatory reaction, peroxynitrite-mediated nitration of proteins, disruption of the blood-brain barrier, and damage in the nigral dopaminergic system Neurobiology of Disease 2004 16 1 190 201 (Pubitemid 38569810)
58. Fan L. W., Pang YI., Lin S., Tien LU. T., Ma T., Rhodes P. G., Cai Z., Minocycline reduces lipopolysaccharide-induced neurological dysfunction and brain injury in the neonatal rat Journal of Neuroscience Research 2005 82 1 71 82 (Pubitemid 41604799)
59. Lee S. M., Yune T. Y., Kim S. J., Kim Y. C., Oh Y. J., Markelonis G. J., Oh T. H., Minocycline inhibits apoptotic cell death via attenuation of TNF- expression following iNOS/NO induction by lipopolysaccharide in neuron/glia co-cultures Journal of Neurochemistry 2004 91 3 568 578 (Pubitemid 39431152)
60. Ravina B., A randomized, double-blind, futility clinical trial of creatine and minocycline in early Parkinson disease Neurology 2006 66 5 664 671 (Pubitemid 43739819)
61. Kieburtz K., Tilley B., Ravina B., Galpern W., Shannon K., Tanner C., Wooten G. F., A pilot clinical trial of creatine and minocycline in early Parkinson disease: 18-month results Clinical Neuropharmacology 2008 31 3 141 150 (Pubitemid 351787110)
62. Griffin M. O., Fricovsky E., Ceballos G., Villarreal F., Tetracyclines: a pleitropic family of compounds with promising therapeutic properties. Review of the literature American Journal of Physiology 2010 299 3 C539 C548
63. Xing B., Xin T., Hunter R. L., Bing G., Pioglitazone inhibition of lipopolysaccharide-induced nitric oxide synthase is associated with altered activity of p38 MAP kinase and PI3K/Akt Journal of Neuroinflammation 2008 5, article 4
64. Zecca L., Wilms H., Geick S., Claasen J. H., Brandenburg L. O., Holzknecht C., Panizza M. L., Zucca F. A., Deuschl G., Sievers J., Lucius R., Human neuromelanin induces neuroinflammation and neurodegeneration in the rat substantia nigra: implications for Parkinson's disease Acta Neuropathologica 2008 116 1 47 55
65. Gao H. M., Kotzbauer P. T., Uryu K., Leight S., Trojanowski J. Q., Lee V. M. Y., Neuroinflammation and oxidation/nitration of -synuclein linked to dopaminergic neurodegeneration Journal of Neuroscience 2008 28 30 7687 7698
66. Zecca L., Stroppolo A., Gatti A., Tampellini D., Toscani M., Gallorini M., Giaveri G., Arosio P., Santambrogio P., Fariello R. G., Karatekin E., Kleinman M. H., Turro N., Hornykiewicz O., Zucca F. A., The role of iron and molecules in the neuronal vulnerability of locus coeruleus and substantia nigra during aging Proceedings of the National Academy of Sciences of the United States of America 2004 101 26 9843 9848 (Pubitemid 38869324)
67. Mittelbronn M., Dietz K., Schluesener H. J., Meyermann R., Local distribution of microglia in the normal adult human central nervous system differs by up to one order of magnitude Acta Neuropathologica 2001 101 3 249 255 (Pubitemid 32219759)
68. Lawson L. J., Perry V. H., Dri P., Gordon S., Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain Neuroscience 1990 39 1 151 170
69. Miklossy J., Chronic inflammation and amyloidogenesis in Alzheimer's diseaserole of spirochetes Journal of Alzheimer's Disease 2008 13 4 381 391 (Pubitemid 352039022)
70. Roth A. D., Ramrez G., Alarcn R., von Bernhardi R., Oligodendrocytes damage in Alzheimer's disease: beta amyloid toxicity and inflammation Biological Research 2005 38 4 381 387