Endotoxin: Is it an environmental factor in the cause of Parkinson's disease? [2]

Occupational and Environmental Medicine

Volumn 60, Issue 5, 2003, Pages 378-

  Niehaus, I ^b   Lange, J H ^a  

^a ENVIROSAFE TRAINING AND CONSULTANTS   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; GAMMA INTERFERON; INTERLEUKIN 6; PESTICIDE; SALMONELLA ENDOTOXIN; TUMOR NECROSIS FACTOR ALPHA; ENDOTOXIN;

AGRICULTURE; AIR POLLUTION; ASTROCYTE; BACTERIAL CELL WALL; BLOOD BRAIN BARRIER; BRADYKINESIA; BRAIN CORTEX; CELL ACTIVATION; CENTRAL NERVOUS SYSTEM; CEREBROSPINAL FLUID; CHRONIC INFLAMMATION; COGNITIVE DEFECT; CYTOKINE RELEASE; DISEASE ASSOCIATION; DISEASE EXACERBATION; DOPAMINERGIC NERVE CELL; EMPLOYMENT; ENVIRONMENTAL FACTOR; FEVER; GRAM NEGATIVE BACTERIUM; GRAM NEGATIVE INFECTION; HUMAN; INFLAMMATION; LABORATORY; LEARNING; LETTER; MACROPHAGE ACTIVATION; MICROGLIA; NERVE CELL DEGENERATION; NEURALGIA; NEUROTOXICITY; NONHUMAN; OCCUPATIONAL EXPOSURE; PARKINSON DISEASE; PARKINSONISM; PATHOGENESIS; PATHOPHYSIOLOGY; POLYNEUROPATHY; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RIGIDITY; SALMONELLA MINNESOTA; SEPSIS; SEPTIC SHOCK; SHORT TERM MEMORY; SPATIAL ORIENTATION; SUBSTANTIA NIGRA; TREMOR; WORKER; AIR POLLUTANT; ENVIRONMENTAL EXPOSURE;

BACTERIA (MICROORGANISMS); NEGIBACTERIA; SALMONELLA; SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR MINNESOTA;

AIR POLLUTANTS; ENDOTOXINS; ENVIRONMENTAL EXPOSURE; HUMANS; PARKINSON DISEASE;

EID: 0037734163     PISSN: 13510711     EISSN: None     Source Type: Journal    
DOI: 10.1136/oem.60.5.378     Document Type: Letter

References (15)

1. Tuchsen F, Jensen AA. Agricultural work and the risk of Parkinson's disease in Denmark, 1981-1993. Scand J Work Environ Health 2000;26:359-62.
2. Hubble JP, Cao T, Hassanein RE, et al. Risk factors for Parkinson's disease. Neurology 1993;43:1693-7.
3. Olenchock AS, May JJ, Pratt DS, et al. Presence of endotoxins in different agricultural environments. Am J Ind Med 1990;18:279-84.
4. Thorn J, Beijer L, Jonsson T, et al. Measurement strategies for the determination of airborne bacterial endotoxin in sewage treatment plants. Ann Occup Hyg 2002;46:549-54.
5. Enterline PE, Sykora JL, Keleti G, et al. Endotoxin, cotton dust and cancer. Lancet 1985;2:934-5.
6. Rietschel ET, Brade H. Bacterial endotoxins. Sci Am 1992;267:54-61.
7. Galanos C, Lüderitz O, Rietschel ET, et al. Synthetic and natural Escherichia coli free lipid A express identical endotoxin activities. Eur J Biochem 1985;148:1-5.
8. Burrell R. Human responses to bacterial endotoxin. Circ Shock 1994;43:137-53.
9. Brandtzaeg P, Kierulf P, Gaustad P, et al. Plasma endotoxin as a predictor of multiple organ failure and death in systemic meningococcal disease. J Infect Dis 1989;159:195-204.
10. Herrera AJ, Castano A, Venero JL, et al. The single intranigral injection of LPS as a new model for studying the selective effects of inflammatory reactions on dopaminergic system. Neurobiol Dis 2000;7:429-47.
11. Liu B, Jiang JW, Wilson BC, et al. Systemic infusion of naloxane reduces degeneration of rat substantia nigral dopaminergic neurons induced by intranigral injection of lipopoysaccharide. J Pharmacol Exp Ther 2000;295:125-32.
12. Niehaus I. Parkinsonism caused by lipopolysaccharides in the CNS (a case report). Poster presentation, XIV International Congress on Parkinson's Disease, 27 July - 1 August 2001, Helsinki, Finland. Parkinsonism Relat Disord 2001;7(suppl):128.
13. Taveira da Silva AM, Kaulbach HC, Chuidian FS, et al. Brief report: shock and multiple-organ dysfunction after self-administration of Salmonella endotoxin. N Engl J Med 1993;328:1457-60.
14. Castano A, Herrera AJ, Cano J, et al. The degenerative effect of a single intranigral injection of LPS on the dopaminergic system is prevented by dexamethasone and not mimicked by rh-TNF- alpha, IL-1 beta and IFN-gamma. Neurochemistry 2002;81:150-7.
15. Becker S, Fenton MJ, Soukup JM. Involvement of microbial components and toll-like receptors 2 and 4 in cytokine responses to air pollution particles. Am J Respir Cell Molec Biol 2002;27:611-18.