Structure of Shigella IpgB2 in complex with human RhoA: Implications for the mechanism of bacterial guanine nucleotide exchange factor mimicry

Journal of Biological Chemistry

Volumn 285, Issue 22, 2010, Pages 17197-17208

  Klink, Björn U ^a   Barden, Stephan ^a   Heidler, Thomas V ^a   Borchers, Christina ^a   Ladwein, Markus ^a   Stradal, Theresia E B ^a,b   Rottner, Klemens ^a   Heinz, Dirk W ^a  

^a HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^b UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN DYNAMICS; BACTERIAL PATHOGENESIS; CONFORMATIONAL CHANGE; CYTOSKELETONS; EUKARYOTIC CELLS; GTP BINDING; GTPASES; GUANINE NUCLEOTIDE EXCHANGE FACTORS; KEY REGULATORS; MODE OF ACTION; MOLECULAR MECHANISM; NUCLEOTIDE EXCHANGE; SHIGELLA FLEXNERI; VIRULENCE FACTORS;

BACTERIOLOGY; MAMMALS; METAL IONS; METAL REFINING; POSITIVE IONS; PROTEINS;

NUCLEOTIDES;

GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATASE; MAGNESIUM ION; PROTEIN IPGB2; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; MOLECULAR MECHANICS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN STRUCTURE; SHIGELLA FLEXNERI;

CLONING, MOLECULAR; CYTOSKELETON; GUANINE NUCLEOTIDE EXCHANGE FACTORS; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; HUMANS; IONS; MAGNESIUM; METALS; NUCLEOTIDES; PROTEIN BINDING; PROTEIN CONFORMATION; RAC1 GTP-BINDING PROTEIN; RHOA GTP-BINDING PROTEIN; SHIGELLA FLEXNERI;

BACTERIA (MICROORGANISMS); EUKARYOTA; MAMMALIA; SHIGELLA; SHIGELLA FLEXNERI;

EID: 77952767396     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.107953     Document Type: Article

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