The guanine-nucleotide-exchange factor BopE from Burkholderia pseudomallei adopts a compact version of the Salmonella SopE/SopE2 fold and undergoes a closed-to-open conformational change upon interaction with Cdc42

Biochemical Journal

Volumn 411, Issue 3, 2008, Pages 485-493

  Upadhyay, Abhishek ^a   Wu, Huan Lin ^a   Williams, Christopher ^a,c   Field, Terry ^b   Galyov, Edouard E ^b,d   Van Den Elsen, Jean M H ^a   Bagby, Stefan ^a  

^a University of Bath   (United Kingdom)

^b INSTITUTE FOR ANIMAL HEALTH   (United Kingdom)

^c UNIVERSITY OF BRISTOL   (United Kingdom)

^d UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

Bacterial pathogen; Guanine nucleotide exchange factor; Protein structure; Protein protein interaction; Rho GTPase; Type III secretion

Indexed keywords

CATALYST ACTIVITY; CONFORMATIONS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEOTIDES; PATHOGENS;

GUANINE-NUCLEOTIDE-EXCHANGE FACTOR; PROTEIN PROTEIN INTERACTION; RHO GTPASE;

PROTEINS;

ARGININE; BURKHOLDERIA PSEUDOMALLEI BOPE PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; PROLINE; PROTEIN CDC42; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; SALMONELLA SOPE PROTEIN; SALMONELLA SOPE2 PROTEIN; BACTERIAL PROTEIN; SOPE PROTEIN, SALMONELLA; UNCLASSIFIED DRUG;

ARTICLE; BURKHOLDERIA PSEUDOMALLEI; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SALMONELLA; TYPE III SECRETION SYSTEM; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; HUMAN; KINETICS; METABOLISM; MUTATION; NUCLEAR MAGNETIC RESONANCE; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN QUATERNARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; STRUCTURAL HOMOLOGY; TITRIMETRY;

BACTERIA (MICROORGANISMS); BURKHOLDERIA PSEUDOMALLEI; SALMONELLA;

BACTERIAL PROTEINS; BURKHOLDERIA PSEUDOMALLEI; CDC42 GTP-BINDING PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; KINETICS; MODELS, MOLECULAR; MUTATION; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; SALMONELLA; STRUCTURAL HOMOLOGY, PROTEIN; TITRIMETRY;

EID: 42449139551     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20071546     Document Type: Article

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