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Volumn 22, Issue 6, 2011, Pages 649-657

Lentiviral vectors: Their molecular design, safety, and use in laboratory and preclinical research

Author keywords

[No Author keywords available]

Indexed keywords

LENTIVIRUS VECTOR;

EID: 79958211842     PISSN: 10430342     EISSN: 15577422     Source Type: Journal    
DOI: 10.1089/hum.2011.058     Document Type: Article
Times cited : (71)

References (118)
  • 1
    • 0022495870 scopus 로고
    • Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone
    • Adachi, A., Gendelman, H.E., Koenig, S., et al. (1986). Production of acquired immunodeficiency syndrome-associated retrovi-rus in human and nonhuman cells transfected with an infectious molecular clone. J. Virol. 59, 284-291. (Pubitemid 16013975)
    • (1986) Journal of Virology , vol.59 , Issue.2 , pp. 284-291
    • Adachi, A.1    Gendelman, H.E.2    Koenig, S.3
  • 2
    • 65549123755 scopus 로고    scopus 로고
    • Forward RNAi screens in primary human hematopoietic stem/progenitor cells
    • Ali, N., Karlsson, C., Aspling, M., et al. (2009). Forward RNAi screens in primary human hematopoietic stem/progenitor cells. Blood 113, 3690-3695.
    • (2009) Blood , vol.113 , pp. 3690-3695
    • Ali, N.1    Karlsson, C.2    Aspling, M.3
  • 3
    • 79953881831 scopus 로고    scopus 로고
    • Highly efficient miRNA mediated reprogramming ofmouse and human somatic cells to pluripotency
    • Anokye-Danso, F., Trivedi, C.M., Johr, D., et al. (2011). Highly efficient miRNA mediated reprogramming ofmouse and human somatic cells to pluripotency. Cell Stem Cell 8, 378-388.
    • (2011) Cell Stem Cell , vol.8 , pp. 378-388
    • Anokye-Danso, F.1    Trivedi, C.M.2    Johr, D.3
  • 4
    • 0016263819 scopus 로고
    • Temperature-sensitive DNA polymerase from Rous sarcoma virus mutants
    • Baltimore, D., Verma, I.M., Drost, S., and Mason, W.S. (1974). Temperature-sensitive DNA polymerase from Rous sarcoma virus mutants. Cancer 34(Suppl. 4), 1395-1397.
    • (1974) Cancer , vol.34 , Issue.SUPPL. 4 , pp. 1395-1397
    • Baltimore, D.1    Verma, I.M.2    Drost, S.3    Mason, W.S.4
  • 5
    • 38649094609 scopus 로고    scopus 로고
    • Sequential expression of pluripotency markers during direct re-programming of mouse somatic cells
    • DOI 10.1016/j.stem.2008.01.004, PII S1934590908000052
    • Brambrink, T., Foreman, R., Welstead, G.G., et al. (2008). Sequential expression of pluripotency markers during direct re-programming of mouse somatic cells. Cell Stem Cell 2, 151-159. (Pubitemid 351168714)
    • (2008) Cell Stem Cell , vol.2 , Issue.2 , pp. 151-159
    • Brambrink, T.1    Foreman, R.2    Welstead, G.G.3    Lengner, C.J.4    Wernig, M.5    Suh, H.6    Jaenisch, R.7
  • 7
    • 33646564701 scopus 로고    scopus 로고
    • Endogenous microRNA regulation suppresses transgene expression in hematopoietic lineages and enables stable gene transfer
    • Brown, B.D., Venneri, M.A., Zingale, A., et al. (2006). Endogenous microRNA regulation suppresses transgene expression in hematopoietic lineages and enables stable gene transfer. Nat. Med. 12, 585-591.
    • (2006) Nat. Med. , vol.12 , pp. 585-591
    • Brown, B.D.1    Venneri, M.A.2    Zingale, A.3
  • 9
    • 33750508543 scopus 로고    scopus 로고
    • Is it going to be SIN? A European Society of Gene Therapy commentary. Phasing-out the clinical use of non self-inactivating murine leukemia virus vectors: Initiative on hold
    • DOI 10.1002/jgm.966
    • Buchholz, C.J., and Cichutek, K. (2006). Is it going to be SIN?: A European Society of Gene Therapy commentary. Phasing-out the clinical use of non self-inactivating murine leukemia virus vectors: Initiative on hold. J. Gene Med. 8, 1274-1276. (Pubitemid 44660526)
    • (2006) Journal of Gene Medicine , vol.8 , Issue.10 , pp. 1274-1276
    • Buchholz, C.J.1    Cichutek, K.2
  • 10
    • 7444262816 scopus 로고    scopus 로고
    • Ahard way tothe nucleus
    • Bukrinsky,M.(2004).Ahard way tothe nucleus. Mol. Med. 10, 1-5.
    • (2004) Mol. Med. , vol.10 , pp. 1-5
    • Bukrinsky, M.1
  • 12
    • 33845935445 scopus 로고    scopus 로고
    • KRAB can repress lentivirus proviral transcription independently of integration site
    • DOI 10.1074/jbc.M602843200
    • Bulliard, Y., Wiznerowicz, M., Barde, I., and Trono, D. (2006). KRAB can repress lentivirus proviral transcription independently of integration site. J. Biol. Chem. 281, 35742-35746. (Pubitemid 46041304)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.47 , pp. 35742-35746
    • Bulliard, Y.1    Wiznerowicz, M.2    Barde, I.3    Trono, D.4
  • 13
    • 70449427834 scopus 로고    scopus 로고
    • Hematopoietic stem cell gene therapy with a lentiviral vector in X-linked adrenoleukodystrophy
    • Cartier, N., Hacein-Bey-Abina, S., Bartholomae, C.C., et al. (2009). Hematopoietic stem cell gene therapy with a lentiviral vector in X-linked adrenoleukodystrophy. Science 326, 818-823.
    • (2009) Science , vol.326 , pp. 818-823
    • Cartier, N.1    Hacein-Bey-Abina, S.2    Bartholomae, C.C.3
  • 14
    • 78650987483 scopus 로고    scopus 로고
    • High-definition mapping of retroviral integration sites defines the fate of allogeneic T cells after donor lymphocyte infusion
    • Cattoglio, C., Maruggi, G., Bartholomae, C., et al. (2010). High-definition mapping of retroviral integration sites defines the fate of allogeneic T cells after donor lymphocyte infusion. PLoS One 5, e15688.
    • (2010) PLoS One , vol.5
    • Cattoglio, C.1    Maruggi, G.2    Bartholomae, C.3
  • 15
    • 77956928344 scopus 로고    scopus 로고
    • Transfusion independence and HMGA2 activation after gene therapy of human b-thalassaemia
    • Cavazzana-Calvo, M., Payen, E., Negre, O., et al. (2010). Transfusion independence and HMGA2 activation after gene therapy of human b-thalassaemia. Nature 467, 318-322.
    • (2010) Nature , vol.467 , pp. 318-322
    • Cavazzana-Calvo, M.1    Payen, E.2    Negre, O.3
  • 16
    • 79956018909 scopus 로고    scopus 로고
    • Is normal hematopoiesis maintained solely by long-term multi-potent stem cells?
    • Cavazzana-Calvo, M., Fischer, A., Bushman, F.D., et al. (2011). Is normal hematopoiesis maintained solely by long-term multi-potent stem cells? Blood 117, 4420-4424.
    • (2011) Blood , vol.117 , pp. 4420-4424
    • Cavazzana-Calvo, M.1    Fischer, A.2    Bushman, F.D.3
  • 17
    • 0037271977 scopus 로고    scopus 로고
    • Self-inactivating lentiviral vectors and a sensitive Cre-loxP reporter system
    • Chang, L.J., and Zaiss, A.K. (2003). Self-inactivating lentiviral vectors and a sensitive Cre-loxP reporter system. Methods Mol. Med. 76, 367-382.
    • (2003) Methods Mol. Med. , vol.76 , pp. 367-382
    • Chang, L.J.1    Zaiss, A.K.2
  • 18
    • 66149165885 scopus 로고    scopus 로고
    • Polycistronic lentiviral vector for "hit and run" reprogramming of adult skin fibroblasts to induced pluripotent stem cells
    • Chang, C.W., Lai, Y.S., Pawlik, K.M., et al. (2009). Polycistronic lentiviral vector for "hit and run" reprogramming of adult skin fibroblasts to induced pluripotent stem cells. Stem Cells 27, 1042-1049.
    • (2009) Stem Cells , vol.27 , pp. 1042-1049
    • Chang, C.W.1    Lai, Y.S.2    Pawlik, K.M.3
  • 19
    • 1542395056 scopus 로고    scopus 로고
    • Identification of a novel proliferation-inducing determinant using lentiviral expression cloning
    • Chilov, D., Fux, C., Joch, H., and Fussenegger, M. (2003). Identification of a novel proliferation-inducing determinant using lentiviral expression cloning. Nucleic Acids Res. 31, e113.
    • (2003) Nucleic Acids Res. , vol.31
    • Chilov, D.1    Fux, C.2    Joch, H.3    Fussenegger, M.4
  • 20
    • 79952183480 scopus 로고    scopus 로고
    • Replication-competent lentivirus analysis of clinical grade vector products
    • Cornetta, K., Yao, J., Jasti, A., et al. (2011). Replication-competent lentivirus analysis of clinical grade vector products. Mol. Ther. 19, 557-566.
    • (2011) Mol. Ther. , vol.19 , pp. 557-566
    • Cornetta, K.1    Yao, J.2    Jasti, A.3
  • 23
    • 0035145366 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 2 lentiviral vectors: Packaging signal and splice donor in expression and encapsidation
    • D'Costa, J., Brown, H., Kundra, P., et al. (2001). Human immunodeficiency virus type 2 lentiviral vectors: Packaging signal and splice donor in expression and encapsidation. J. Gen. Virol. 82, 425-434. (Pubitemid 32123896)
    • (2001) Journal of General Virology , vol.82 , Issue.2 , pp. 425-434
    • D'Costa, J.1    Brown, H.M.2    Kundra, P.3    Davis-Warren, A.4    Arya, S.K.5
  • 24
    • 0038529610 scopus 로고    scopus 로고
    • Noninvasive imaging of lentiviral-mediated reporter gene expression in living mice
    • DOI 10.1016/S1525-0016(03)00070-4
    • De, A., Lewis, X.Z., and Gambhir, S.S. (2003). Noninvasive imaging of lentiviral-mediated reporter gene expression in living mice. Mol. Ther. 7, 681-691. (Pubitemid 36626248)
    • (2003) Molecular Therapy , vol.7 , Issue.5 , pp. 681-691
    • De, A.1    Lewis, X.Z.2    Gambhir, S.S.3
  • 25
    • 13744263861 scopus 로고    scopus 로고
    • Positional effects of the central DNA flap in HIV-1-derived lentiviral vectors
    • DOI 10.1016/j.bbrc.2005.01.052
    • De, R.J., Van, M.B., and Debyser, Z. (2005). Positional effects of the central DNA flap in HIV-1-derived lentiviral vectors. Biochem. Biophys. Res. Commun. 328, 987-994. (Pubitemid 40238733)
    • (2005) Biochemical and Biophysical Research Communications , vol.328 , Issue.4 , pp. 987-994
    • De Rijck, J.1    Van Maele, B.2    Debyser, Z.3
  • 27
    • 0035661288 scopus 로고    scopus 로고
    • Lentivirus in the clinic
    • Dropulić, B. (2001). Lentivirus in the clinic. Mol. Ther. 4, 511-512.
    • (2001) Mol. Ther. , vol.4 , pp. 511-512
    • Dropulić, B.1
  • 30
    • 0025963855 scopus 로고
    • Pseudotype formation of murine leukemia virus with the G protein of vesicular stomatitis virus
    • Emi, N., Friedmann, T., and Yee, J.K. (1991). Pseudotype formation of murine leukemia virus with the G protein of vesicular stomatitis virus. J. Virol. 65, 1202-1207.
    • (1991) J. Virol. , vol.65 , pp. 1202-1207
    • Emi, N.1    Friedmann, T.2    Yee, J.K.3
  • 31
    • 0032601402 scopus 로고    scopus 로고
    • HIV integrase structure and function
    • Esposito, D., and Craigie, R. (1999). HIV integrase structure and function. Adv. Virus Res. 52, 319-333.
    • (1999) Adv. Virus Res. , vol.52 , pp. 319-333
    • Esposito, D.1    Craigie, R.2
  • 34
    • 78650786485 scopus 로고    scopus 로고
    • Influence of insulators on transgene expression from integrating and non-integrating lentiviral vectors
    • Grandchamp, N., Henriot, D., Philippe, S., et al. (2011). Influence of insulators on transgene expression from integrating and non-integrating lentiviral vectors. Genet. Vaccines Ther. 9, 1.
    • (2011) Genet. Vaccines Ther. , vol.9 , pp. 1
    • Grandchamp, N.1    Henriot, D.2    Philippe, S.3
  • 35
    • 33747625913 scopus 로고    scopus 로고
    • Optimization of a genome-wide disordered lentivector-based short hairpin RNA library
    • DOI 10.1134/S002689330603006X
    • Guryanova, O.A., Makhanov, M., Chenchik, A.A., et al. (2006). Optimization of a genome-wide disordered lentivector-based short hairpin RNA library. Mol. Biol. 40, 396-405. (Pubitemid 44264843)
    • (2006) Molecular Biology , vol.40 , Issue.3 , pp. 396-405
    • Guryanova, O.A.1    Makhanov, M.2    Chenchik, A.A.3    Chumakov, P.M.4    Frolova, E.I.5
  • 37
    • 51349090473 scopus 로고    scopus 로고
    • Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1
    • Hacein-Bey-Abina, S., Garrigue, A., Wang, G.P., et al. (2008). Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1. J. Clin. Invest 118, 3132-3142.
    • (2008) J. Clin. Invest , vol.118 , pp. 3132-3142
    • Hacein-Bey-Abina, S.1    Garrigue, A.2    Wang, G.P.3
  • 38
    • 63949087408 scopus 로고    scopus 로고
    • Optimized lentiviral vector design improves titer and transgene expression of vectors containing the chicken b-globin locus HS4 insulator element
    • Hanawa, H., Yamamoto, M., Zhao, H., et al. (2009). Optimized lentiviral vector design improves titer and transgene expression of vectors containing the chicken b-globin locus HS4 insulator element. Mol. Ther. 17, 667-674.
    • (2009) Mol. Ther. , vol.17 , pp. 667-674
    • Hanawa, H.1    Yamamoto, M.2    Zhao, H.3
  • 39
    • 57449112781 scopus 로고    scopus 로고
    • Inducible and reversible gene silencing by stable integration of an shRNA-encoding lentivirus in transgenic rats
    • Herold, M.J., van den Brandt, J., Seibler, J., and Reichardt, H.M. (2008). Inducible and reversible gene silencing by stable integration of an shRNA-encoding lentivirus in transgenic rats. Proc. Natl. Acad. Sci. U.S.A. 105, 18507-18512.
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 18507-18512
    • Herold, M.J.1    Van Den Brandt, J.2    Seibler, J.3    Reichardt, H.M.4
  • 40
    • 50849144675 scopus 로고    scopus 로고
    • A drug-inducible system for direct reprogramming of human somatic cells to pluripotency
    • Hockemeyer, D., Soldner, F., Cook, E.G., et al. (2008). A drug-inducible system for direct reprogramming of human somatic cells to pluripotency. Cell Stem Cell 3, 346-353.
    • (2008) Cell Stem Cell , vol.3 , pp. 346-353
    • Hockemeyer, D.1    Soldner, F.2    Cook, E.G.3
  • 42
    • 70350544173 scopus 로고    scopus 로고
    • N-Glycosylation engineering of biopharmaceutical expression systems
    • Jacobs, P.P., and Callewaert, N. (2009). N-Glycosylation engineering of biopharmaceutical expression systems. Curr. Mol. Med. 9, 774-800.
    • (2009) Curr. Mol. Med. , vol.9 , pp. 774-800
    • Jacobs, P.P.1    Callewaert, N.2
  • 43
    • 70349873365 scopus 로고    scopus 로고
    • Amelioration of psoriasis by anti-TNF-a RNAi in the xenograft transplantation model
    • Jakobsen, M., Stenderup, K., Rosada, C., et al. (2009). Amelioration of psoriasis by anti-TNF-a RNAi in the xenograft transplantation model. Mol. Ther. 17, 1743-1753.
    • (2009) Mol. Ther. , vol.17 , pp. 1743-1753
    • Jakobsen, M.1    Stenderup, K.2    Rosada, C.3
  • 44
    • 77956229309 scopus 로고    scopus 로고
    • Application of bio-luminescence imaging to therapeutic intervention of herpes simplex virus type I-thymidine kinase/ganciclovir in glioma
    • Jang, S.J., Kang, J.H., Kim, K.I., et al. (2010). Application of bio-luminescence imaging to therapeutic intervention of herpes simplex virus type I-thymidine kinase/ganciclovir in glioma. Cancer Lett. 297, 84-90.
    • (2010) Cancer Lett. , vol.297 , pp. 84-90
    • Jang, S.J.1    Kang, J.H.2    Kim, K.I.3
  • 45
    • 0347770330 scopus 로고    scopus 로고
    • Molecular biology of human immunodeficiency virus type-1
    • Joshi, S., and Joshi, R.L. (1996). Molecular biology of human immunodeficiency virus type-1. Transfus. Sci. 17, 351-378.
    • (1996) Transfus. Sci. , vol.17 , pp. 351-378
    • Joshi, S.1    Joshi, R.L.2
  • 46
    • 0034202721 scopus 로고    scopus 로고
    • Len-tiviral vectors: Regulated gene expression
    • Kafri, T., van Praag, H., Gage, F.H., and Verma, I.M. (2000). Len-tiviral vectors: Regulated gene expression. Mol. Ther. 1, 516-521.
    • (2000) Mol. Ther. , vol.1 , pp. 516-521
    • Kafri, T.1    Van Praag, H.2    Gage, F.H.3    Verma, I.M.4
  • 47
    • 4644332771 scopus 로고    scopus 로고
    • A lentiviral cDNA library employing lambda recombination used to clone an inhibitor of human immunodeficiency virus type 1-induced cell death
    • DOI 10.1128/JVI.78.20.11352-11359.2004
    • Kawano, Y., Yoshida, T., Hieda, K., et al. (2004). A lentiviral cDNA library employing lambda recombination used to clone an inhibitor of human immunodeficiency virus type 1-induced cell death. J. Virol. 78, 11352-11359. (Pubitemid 39299676)
    • (2004) Journal of Virology , vol.78 , Issue.20 , pp. 11352-11359
    • Kawano, Y.1    Yoshida, T.2    Hieda, K.3    Aoki, J.4    Miyoshi, H.5    Koyanagi, Y.6
  • 48
    • 0031985685 scopus 로고    scopus 로고
    • Minimal requirement for a lentivirus vector based on human immunodeficiency virus type 1
    • Kim, V.N., Mitrophanous, K., Kingsman, S.M., and Kingsman, A.J. (1998). Minimal requirement for a lentivirus vector based on human immunodeficiency virus type 1. J. Virol. 72, 811-816. (Pubitemid 28048905)
    • (1998) Journal of Virology , vol.72 , Issue.1 , pp. 811-816
    • Kim, V.N.1    Mitrophanous, K.2    Kingsman, S.M.3    Kingsman, A.J.4
  • 49
    • 11844288284 scopus 로고    scopus 로고
    • Potential oncogene activity of the woodchuck hepatitis post-transcriptional regulatory element (WPRE)
    • DOI 10.1038/sj.gt.3302417
    • Kingsman, S.M., Mitrophanous, K., and Olsen, J.C. (2005). Potential oncogene activity of the woodchuck hepatitis post-transcriptional regulatory element (WPRE). Gene Ther. 12, 3-4. (Pubitemid 40090038)
    • (2005) Gene Therapy , vol.12 , Issue.1 , pp. 3-4
    • Kingsman, S.M.1    Mitrophanous, K.2    Olsen, J.C.3
  • 50
    • 0036359284 scopus 로고    scopus 로고
    • Cre/loxP recombination system and gene targeting
    • Kuhn, R., and Torres, R.M. (2002). Cre/loxP recombination system and gene targeting. Methods Mol. Biol. 180, 175-204.
    • (2002) Methods Mol. Biol. , vol.180 , pp. 175-204
    • Kuhn, R.1    Torres, R.M.2
  • 51
    • 55649086632 scopus 로고    scopus 로고
    • Construction of a high-performance human fetal liver-derived lentiviral cDNA library
    • Kurita, R., Oikawa, T., Okada, M., et al. (2008). Construction of a high-performance human fetal liver-derived lentiviral cDNA library. Mol. Cell. Biochem. 319, 181-187.
    • (2008) Mol. Cell. Biochem. , vol.319 , pp. 181-187
    • Kurita, R.1    Oikawa, T.2    Okada, M.3
  • 52
    • 74149091763 scopus 로고    scopus 로고
    • Characterisation of eGFP-transgenic BALB/c mouse strain established by len-tiviral transgenesis
    • Kvell, K., Czompoly, T., Hiripi, L., et al. (2010). Characterisation of eGFP-transgenic BALB/c mouse strain established by len-tiviral transgenesis. Transgenic Res. 19, 105-112.
    • (2010) Transgenic Res. , vol.19 , pp. 105-112
    • Kvell, K.1    Czompoly, T.2    Hiripi, L.3
  • 53
    • 77955797425 scopus 로고    scopus 로고
    • Inducible gene and shRNA expression in resident hematopoietic stem cells in vivo
    • Laurenti, E., Barde, I., Verp, S., et al. (2010). Inducible gene and shRNA expression in resident hematopoietic stem cells in vivo. Stem Cells 28, 1390-1398.
    • (2010) Stem Cells , vol.28 , pp. 1390-1398
    • Laurenti, E.1    Barde, I.2    Verp, S.3
  • 55
    • 0036829522 scopus 로고    scopus 로고
    • Transcriptional activation of interleukin-8 by b-catenin-Tcf4
    • Levy, L., Neuveut, C., Renard, C.A., et al. (2002). Transcriptional activation of interleukin-8 by b-catenin-Tcf4. J. Biol. Chem. 277, 42386-42393.
    • (2002) J. Biol. Chem. , vol.277 , pp. 42386-42393
    • Levy, L.1    Neuveut, C.2    Renard, C.A.3
  • 56
    • 11844260706 scopus 로고    scopus 로고
    • Lentiviral vector delivery of recombinant small interfering RNA expression cassettes
    • DOI 10.1016/S0076-6879(04)92013-7, PII S0076687904920137
    • Li, M.J., and Rossi, J.J. (2005). Lentiviral vector delivery of re-combinant small interfering RNA expression cassettes. Methods Enzymol. 392, 218-226. (Pubitemid 40092517)
    • (2005) Methods in Enzymology , vol.392 , pp. 218-226
    • Li, M.-J.1    Rossi, J.J.2
  • 57
    • 77954362697 scopus 로고    scopus 로고
    • Future perspective of induced pluripotent stem cells for diagnosis, drug screening and treatment of human diseases
    • Lian, Q., Chow, Y., Esteban, M.A., et al. (2010). Future perspective of induced pluripotent stem cells for diagnosis, drug screening and treatment of human diseases. Thromb. Hae-most. 104, 39-44.
    • (2010) Thromb. Hae-most. , vol.104 , pp. 39-44
    • Lian, Q.1    Chow, Y.2    Esteban, M.A.3
  • 58
    • 79960027863 scopus 로고    scopus 로고
    • Imaging stem cell-derived persistent foci after in vivo selection of lentiviral MGMT-P140K transduced murine bone marrow cells
    • in press
    • Lin, Y., Cheung, P., Roth, J.C., et al. (2011). Imaging stem cell-derived persistent foci after in vivo selection of lentiviral MGMT-P140K transduced murine bone marrow cells. Mol. Ther. (in press).
    • (2011) Mol. Ther
    • Lin, Y.1    Cheung, P.2    Roth, J.C.3
  • 60
    • 79953072037 scopus 로고    scopus 로고
    • Polyclonal fluctuation of lentiviral vector-transduced and expanded murine hematopoietic stem cells
    • Maetzig, T., Brugman, M.H., Bartels, S., et al. (2011). Polyclonal fluctuation of lentiviral vector-transduced and expanded murine hematopoietic stem cells. Blood 117, 3053-3064.
    • (2011) Blood , vol.117 , pp. 3053-3064
    • Maetzig, T.1    Brugman, M.H.2    Bartels, S.3
  • 61
    • 50849142559 scopus 로고    scopus 로고
    • A high-efficiency system for the generation and study of human induced pluripotent stem cells
    • Maherali, N., Ahfeldt, T., Rigamonti, A., et al. (2008). A high-efficiency system for the generation and study of human induced pluripotent stem cells. Cell Stem Cell 3, 340-345.
    • (2008) Cell Stem Cell , vol.3 , pp. 340-345
    • Maherali, N.1    Ahfeldt, T.2    Rigamonti, A.3
  • 62
    • 0033857473 scopus 로고    scopus 로고
    • Development of minimal lentivirus vectors derived from simian immunodeficiency virus (SIVmac251) and their use for gene transfer into human dendritic cells
    • DOI 10.1128/JVI.74.18.8307-8315.2000
    • Mangeot, P.E., Negre, D., Dubois, B., et al. (2000). Development of minimal lentivirus vectors derived from simian immunodeficiency virus (SIVmac251) and their use for gene transfer into human dendritic cells. J. Virol. 74, 8307-8315. (Pubitemid 30666680)
    • (2000) Journal of Virology , vol.74 , Issue.18 , pp. 8307-8315
    • Mangeot, P.-E.1    Negre, D.2    Dubois, B.3    Winter, A.J.4    Leissner, P.5    Mehtali, M.6    Kaiserlian, D.7    Cosset, F.-L.8    Darlix, J.-L.9
  • 64
    • 67349120266 scopus 로고    scopus 로고
    • Transcrip-tional enhancers induce insertional gene deregulation independently from the vector type and design
    • Maruggi, G., Porcellini, S., Facchini, G., et al. (2009). Transcrip-tional enhancers induce insertional gene deregulation independently from the vector type and design. Mol. Ther. 17, 851-856.
    • (2009) Mol. Ther. , vol.17 , pp. 851-856
    • Maruggi, G.1    Porcellini, S.2    Facchini, G.3
  • 65
    • 58149330085 scopus 로고    scopus 로고
    • Development of a novel mouse glioma model using lentiviral vectors
    • Marumoto, T., Tashiro, A., Friedmann-Morvinski, D., et al. (2009). Development of a novel mouse glioma model using lentiviral vectors. Nat. Med. 15, 110-116.
    • (2009) Nat. Med. , vol.15 , pp. 110-116
    • Marumoto, T.1    Tashiro, A.2    Friedmann-Morvinski, D.3
  • 67
    • 65249108107 scopus 로고    scopus 로고
    • Preventing and exploiting the oncogenic potential of integrating gene vectors
    • Modlich, U., and Baum, C. (2009). Preventing and exploiting the oncogenic potential of integrating gene vectors. J. Clin. Invest. 119, 755-758.
    • (2009) J. Clin. Invest. , vol.119 , pp. 755-758
    • Modlich, U.1    Baum, C.2
  • 68
    • 70449127230 scopus 로고    scopus 로고
    • Insertional transformation of hematopoietic cells by self-inactivating len-tiviral and gammaretroviral vectors
    • Modlich, U., Navarro, S., Zychlinski, D., et al. (2009). Insertional transformation of hematopoietic cells by self-inactivating len-tiviral and gammaretroviral vectors. Mol. Ther. 17, 1919-1928.
    • (2009) Mol. Ther. , vol.17 , pp. 1919-1928
    • Modlich, U.1    Navarro, S.2    Zychlinski, D.3
  • 69
    • 33646033137 scopus 로고    scopus 로고
    • A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen
    • Moffat, J., Grueneberg, D.A., Yang, X., et al. (2006). A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen. Cell 124, 1283-1298.
    • (2006) Cell , vol.124 , pp. 1283-1298
    • Moffat, J.1    Grueneberg, D.A.2    Yang, X.3
  • 71
    • 65249101260 scopus 로고    scopus 로고
    • The genotoxic potential of retroviral vectors is strongly modulated by vector design and integration site selection in a mouse model of HSC gene therapy
    • Montini, E., Cesana, D., Schmidt, M., et al. (2009). The genotoxic potential of retroviral vectors is strongly modulated by vector design and integration site selection in a mouse model of HSC gene therapy. J. Clin. Invest 119, 964-975.
    • (2009) J. Clin. Invest , vol.119 , pp. 964-975
    • Montini, E.1    Cesana, D.2    Schmidt, M.3
  • 72
    • 79953316849 scopus 로고    scopus 로고
    • Simple generation of human induced pluripotent stem cells using poly(b-amino esters) as non-viral gene delivery system
    • Montserrat, N., Garreta, B.E., Gonzalez, F., et al. (2011). Simple generation of human induced pluripotent stem cells using poly(b-amino esters) as non-viral gene delivery system. J. Biol. Chem. 286, 12417-12428.
    • (2011) J. Biol. Chem. , vol.286 , pp. 12417-12428
    • Montserrat, N.1    Garreta, B.E.2    Gonzalez, F.3
  • 73
    • 0032191380 scopus 로고    scopus 로고
    • Lentiviruses as gene transfer agents for delivery to non-dividing cells
    • DOI 10.1016/S0958-1669(98)80029-3
    • Naldini, L. (1998). Lentiviruses as gene transfer agents for delivery to non-dividing cells. Curr. Opin. Biotechnol. 9, 457-463. (Pubitemid 28478965)
    • (1998) Current Opinion in Biotechnology , vol.9 , Issue.5 , pp. 457-463
    • Naldini, L.1
  • 75
    • 36049014397 scopus 로고    scopus 로고
    • A roadmap to safe, efficient, and stable lentivirus-mediated gene therapy with hematopoietic cell transplantation
    • DOI 10.1016/j.bbmt.2007.09.014, PII S1083879107004879
    • Neschadim, A., McCart, J.A., Keating, A., and Medin, J.A. (2007). A roadmap to safe, efficient, and stable lentivirus-mediated gene therapy with hematopoietic cell transplantation. Biol. Blood Marrow Transplant. 13, 1407-1416. (Pubitemid 350091394)
    • (2007) Biology of Blood and Marrow Transplantation , vol.13 , Issue.12 , pp. 1407-1416
    • Neschadim, A.1    McCart, J.A.2    Keating, A.3    Medin, J.A.4
  • 76
    • 55249087037 scopus 로고    scopus 로고
    • Resistance of mature T cells to oncogene transformation
    • Newrzela, S., Cornils, K., Li, Z., et al. (2008). Resistance of mature T cells to oncogene transformation. Blood 112, 2278-2286.
    • (2008) Blood , vol.112 , pp. 2278-2286
    • Newrzela, S.1    Cornils, K.2    Li, Z.3
  • 77
    • 18144403552 scopus 로고    scopus 로고
    • Molecular strategy to inhibit HIV-1 replication
    • Nielsen, N.J., Pedersen, F.S., and Kjems, J. (2005). Molecular strategy to inhibit HIV-1 replication. Retrovirology 2, 10.
    • (2005) Retrovirology , vol.2 , pp. 10
    • Nielsen, N.J.1    Pedersen, F.S.2    Kjems, J.3
  • 80
    • 0025693946 scopus 로고
    • Molecular pathogenesis of HIV-1
    • O'Brien, W.A., Zack, J.A., and Chen, I.S. (1990). Molecular pathogenesis of HIV-1. AIDS 4(Suppl. 1), S41-S48.
    • (1990) AIDS , vol.4 , Issue.SUPPL. 1
    • O'Brien, W.A.1    Zack, J.A.2    Chen, I.S.3
  • 81
    • 0028237189 scopus 로고
    • Analysis in human immunodeficiency virus type 1 vectors of cis-acting sequences that affect gene transfer into human lymphocytes
    • Parolin, C., Dorfman, T., Palu, G., et al. (1994). Analysis in human immunodeficiency virus type 1 vectors of cis-acting sequences that affect gene transfer into human lymphocytes. J. Virol. 68, 3888-3895. (Pubitemid 24177414)
    • (1994) Journal of Virology , vol.68 , Issue.6 , pp. 3888-3895
    • Parolin, C.1    Dorfman, T.2    Palu, G.3    Gottlinger, H.4    Sodroski, J.5
  • 82
    • 77955850887 scopus 로고    scopus 로고
    • Advances in reprogramming somatic cells to induced pluripotent stem cells
    • Patel, M., and Yang, S. (2010). Advances in reprogramming somatic cells to induced pluripotent stem cells. Stem Cell Rev. 6, 367-380.
    • (2010) Stem Cell Rev. , vol.6 , pp. 367-380
    • Patel, M.1    Yang, S.2
  • 83
  • 85
    • 0030425881 scopus 로고    scopus 로고
    • Conditional mutagenesis in mice: The Cre/loxP recombination system
    • Pluck, A. (1996). Conditional mutagenesis in mice: The Cre/loxP recombination system. Int. J. Exp. Pathol. 77, 269-278. (Pubitemid 27141644)
    • (1996) International Journal of Experimental Pathology , vol.77 , Issue.6 , pp. 269-278
    • Pluck, A.1
  • 86
    • 77449118071 scopus 로고    scopus 로고
    • Use of HIV as a gene transfer vector
    • Pluta, K., and Kacprzak, M.M. (2009). Use of HIV as a gene transfer vector. Acta Biochim. Pol. 56, 531-595.
    • (2009) Acta Biochim. Pol. , vol.56 , pp. 531-595
    • Pluta, K.1    Kacprzak, M.M.2
  • 87
    • 34548303952 scopus 로고    scopus 로고
    • Lentiviral vectors encoding tetracycline-dependent repressors and transactivators for reversible knockdown of gene expression: A comparative study
    • Pluta, K., Diehl, W., Zhang, X.Y., et al. (2007). Lentiviral vectors encoding tetracycline-dependent repressors and transactivators for reversible knockdown of gene expression: A comparative study. BMC Biotechnol. 7, 41.
    • (2007) BMC Biotechnol. , vol.7 , pp. 41
    • Pluta, K.1    Diehl, W.2    Zhang, X.Y.3
  • 88
    • 0031953134 scopus 로고    scopus 로고
    • Efficient transduction of nondividing human cells by feline immunodeficiency virus lentiviral vectors
    • DOI 10.1038/nm0398-354
    • Poeschla, E.M., Wong-Staal, F., and Looney, D.J. (1998). Efficient transduction of nondividing human cells by feline immunodeficiency virus lentiviral vectors. Nat. Med. 4, 354-357. (Pubitemid 28144098)
    • (1998) Nature Medicine , vol.4 , Issue.3 , pp. 354-357
    • Poeschla, E.M.1    Wong-Staal, F.2    Looney, D.J.3
  • 89
    • 61849185713 scopus 로고    scopus 로고
    • Serial imaging of human embryonic stem-cell engraftment and teratoma formation in live mouse models
    • Pomper, M.G., Hammond, H., Yu, X., et al. (2009). Serial imaging of human embryonic stem-cell engraftment and teratoma formation in live mouse models. Cell Res. 19, 370-379.
    • (2009) Cell Res. , vol.19 , pp. 370-379
    • Pomper, M.G.1    Hammond, H.2    Yu, X.3
  • 90
    • 0026051132 scopus 로고
    • Gene transfer into human lymphocytes by a defective human immunodeficiency virus type 1 vector
    • Poznansky, M., Lever, A., Bergeron, L., et al. (1991). Gene transfer into human lymphocytes by a defective human immunodeficiency virus type 1 vector. J. Virol. 65, 532-536.
    • (1991) J. Virol. , vol.65 , pp. 532-536
    • Poznansky, M.1    Lever, A.2    Bergeron, L.3
  • 91
    • 0942276845 scopus 로고    scopus 로고
    • Highly efficient lentiviral-mediated human cytokine transgenesis on the NOD/scid background
    • DOI 10.1182/blood-2003-07-2298
    • Punzon, I., Criado, L.M., Serrano, A., et al. (2004). Highly efficient lentiviral-mediated human cytokine transgenesis on the NOD/scid background. Blood 103, 580-582. (Pubitemid 38140089)
    • (2004) Blood , vol.103 , Issue.2 , pp. 580-582
    • Punzon, I.1    Criado, L.M.2    Serrano, A.3    Serrano, F.4    Bernad, A.5
  • 92
    • 0022038928 scopus 로고
    • Molecular organization of the AIDS retrovirus
    • Rabson, A.B., and Martin, M.A. (1985). Molecular organization of the AIDS retrovirus. Cell 40, 477-480.
    • (1985) Cell , vol.40 , pp. 477-480
    • Rabson, A.B.1    Martin, M.A.2
  • 94
    • 1242338786 scopus 로고    scopus 로고
    • Imaging tri-fusion multi-modality reporter gene expression in living subjects
    • Ray, P., De, A., Min, J.J., et al. (2004). Imaging tri-fusion multi-modality reporter gene expression in living subjects. Cancer Res. 64, 1323-1330.
    • (2004) Cancer Res. , vol.64 , pp. 1323-1330
    • A. De, R.P.1    Min, J.J.2
  • 95
    • 77954540080 scopus 로고    scopus 로고
    • Germ-line transmission of lentiviral PGK-EGFP integrants in trans-genic cattle: New perspectives for experimental embryology
    • Reichenbach, M., Lim, T., Reichenbach, H.D., et al. (2010). Germ-line transmission of lentiviral PGK-EGFP integrants in trans-genic cattle: New perspectives for experimental embryology. Transgenic Res. 19, 549-556.
    • (2010) Transgenic Res. , vol.19 , pp. 549-556
    • Reichenbach, M.1    Lim, T.2    Reichenbach, H.D.3
  • 96
    • 33747794587 scopus 로고    scopus 로고
    • Genome-scale loss-of-function screening with a lentiviral RNAi library
    • DOI 10.1038/nmeth924, PII NMETH924
    • Root, D.E., Hacohen, N., Hahn, W.C., et al. (2006). Genome-scale loss-of-function screening with a lentiviral RNAi library. Nat. Methods 3, 715-719. (Pubitemid 44275739)
    • (2006) Nature Methods , vol.3 , Issue.9 , pp. 715-719
    • Root, D.E.1    Hacohen, N.2    Hahn, W.C.3    Lander, E.S.4    Sabatini, D.M.5
  • 97
    • 44249091181 scopus 로고    scopus 로고
    • Production and titration of lentiviral vectors
    • July, Chapter 12, Unit 12.10
    • Salmon P., and Trono D. (2007). Production and titration of lentiviral vectors. Curr. Protoc. Hum. Genet. July, Chapter 12, Unit 12.10
    • (2007) Curr. Protoc. Hum. Genet
    • Salmon, P.1    Trono, D.2
  • 99
    • 77952117231 scopus 로고    scopus 로고
    • Function-based gene identification using enzymatically generated normalized shRNA library and massive parallel sequencing
    • Shtutman, M., Maliyekkel, A., Shao, Y., et al. (2010). Function-based gene identification using enzymatically generated normalized shRNA library and massive parallel sequencing. Proc. Natl. Acad. Sci. U.S.A. 107, 7377-7382.
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 7377-7382
    • Shtutman, M.1    Maliyekkel, A.2    Shao, Y.3
  • 100
    • 60649100077 scopus 로고    scopus 로고
    • Applications of lentiviral vectors for shRNA delivery and transgenesis
    • Singer, O., and Verma, I.M. (2008). Applications of lentiviral vectors for shRNA delivery and transgenesis. Curr. Gene Ther. 8, 483-488.
    • (2008) Curr. Gene Ther. , vol.8 , pp. 483-488
    • Singer, O.1    Verma, I.M.2
  • 101
    • 78649872212 scopus 로고    scopus 로고
    • A genome-wide RNAi screen identifies multiple RSK-dependent regulators of cell migration
    • Smolen, G.A., Zhang, J., Zubrowski, M.J., et al. (2010). A genome-wide RNAi screen identifies multiple RSK-dependent regulators of cell migration. Genes Dev. 24, 2654-2665.
    • (2010) Genes Dev. , vol.24 , pp. 2654-2665
    • Smolen, G.A.1    Zhang, J.2    Zubrowski, M.J.3
  • 102
    • 79952721477 scopus 로고    scopus 로고
    • Feature article: Transdifferentiation of glioblastoma cells into vascular endothelial cells
    • Soda, Y., Marumoto, T., Friedmann-Morvinski, D., et al. (2011). Feature article: Transdifferentiation of glioblastoma cells into vascular endothelial cells. Proc. Natl. Acad. Sci. U.S.A. 108, 4274-4280.
    • (2011) Proc. Natl. Acad. Sci. U.S.A. , vol.108 , pp. 4274-4280
    • Soda, Y.1    Marumoto, T.2    Friedmann-Morvinski, D.3
  • 103
    • 65249149666 scopus 로고    scopus 로고
    • Induced pluripotent stem cell generation using a single lentiviral stem cell cassette
    • Sommer, C.A., Stadtfeld, M., Murphy, G.J., et al. (2009). Induced pluripotent stem cell generation using a single lentiviral stem cell cassette. Stem Cells 27, 543-549.
    • (2009) Stem Cells , vol.27 , pp. 543-549
    • Sommer, C.A.1    Stadtfeld, M.2    Murphy, G.J.3
  • 104
    • 79551624145 scopus 로고    scopus 로고
    • Lentiviral vector platform for production of bioengineered recombinant coagulation factor VIII
    • Spencer, H.T., Denning, G., Gautney, R.E., et al. (2010). Lentiviral vector platform for production of bioengineered recombinant coagulation factor VIII. Mol. Ther. 19, 302-309.
    • (2010) Mol. Ther. , vol.19 , pp. 302-309
    • Spencer, H.T.1    Denning, G.2    Gautney, R.E.3
  • 105
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • DOI 10.1016/j.cell.2006.07.024, PII S0092867406009767
    • Takahashi, K., and Yamanaka, S. (2006). Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126, 663-676. (Pubitemid 44233629)
    • (2006) Cell , vol.126 , Issue.4 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 106
    • 33845788246 scopus 로고    scopus 로고
    • Fetal gene transfer using lentiviral vectors: In vivo detection of gene expression by microPET and optical imaging in fetal and infant monkeys
    • DOI 10.1089/hum.2006.17.1254
    • Tarantal, A.F., Lee, C.C., Jimenez, D.F., and Cherry, S.R. (2006). Fetal gene transfer using lentiviral vectors: In vivo detection of gene expression by microPET and optical imaging in fetal and infant monkeys. Hum. Gene Ther. 17, 1254-1261. (Pubitemid 44975141)
    • (2006) Human Gene Therapy , vol.17 , Issue.12 , pp. 1254-1261
    • Tarantal, A.F.1    Lee, C.C.I.2    Jimenez, D.F.3    Cherry, S.R.4
  • 107
    • 78650874241 scopus 로고    scopus 로고
    • Chicken HS4 insulators have minimal barrier function among progeny of human hematopoietic cells transduced with an HIV1-based lentiviral vector
    • Uchida, N., Washington, K.N., Lap, C.J., et al. (2011). Chicken HS4 insulators have minimal barrier function among progeny of human hematopoietic cells transduced with an HIV1-based lentiviral vector. Mol. Ther. 19, 133-139.
    • (2011) Mol. Ther. , vol.19 , pp. 133-139
    • Uchida, N.1    Washington, K.N.2    Lap, C.J.3
  • 108
    • 0037417772 scopus 로고    scopus 로고
    • Molecular recognition of the human coactivator CBP by the HIV-1 transcriptional activator tat
    • DOI 10.1021/bi0270034
    • Vendel, A.C., and Lumb, K.J. (2003). Molecular recognition of the human coactivator CBP by the HIV-1 transcriptional activator Tat. Biochemistry 42, 910-916. (Pubitemid 36159522)
    • (2003) Biochemistry , vol.42 , Issue.4 , pp. 910-916
    • Vendel, A.C.1    Lumb, K.J.2
  • 109
    • 79953310912 scopus 로고    scopus 로고
    • Lentiviral vector design and imaging approaches to visualize the early stages of cellular reprogramming
    • Warlich, E., Kuehle, J., Cantz, T., et al. (2011). Lentiviral vector design and imaging approaches to visualize the early stages of cellular reprogramming. Mol. Ther. 19, 782-789.
    • (2011) Mol. Ther. , vol.19 , pp. 782-789
    • Warlich, E.1    Kuehle, J.2    Cantz, T.3
  • 110
    • 80055112538 scopus 로고    scopus 로고
    • Generating iPS cells from MEFS through forced expression of Sox-2, Oct-4, c-Myc, and Klf4
    • Welstead, G.G., Brambrink, T., and Jaenisch, R. (2008). Generating iPS cells from MEFS through forced expression of Sox-2, Oct-4, c-Myc, and Klf4. J. Vis. Exp. 14, 734.
    • (2008) J. Vis. Exp. , vol.14 , pp. 734
    • Welstead, G.G.1    Brambrink, T.2    Jaenisch, R.3
  • 111
    • 59449092185 scopus 로고    scopus 로고
    • Single-vector inducible lentiviral RNAi system for oncology target validation
    • Wiederschain, D., Wee, S., Chen, L., et al. (2009). Single-vector inducible lentiviral RNAi system for oncology target validation. Cell Cycle 8, 498-504.
    • (2009) Cell Cycle , vol.8 , pp. 498-504
    • Wiederschain, D.1    Wee, S.2    Chen, L.3
  • 112
    • 11344252479 scopus 로고    scopus 로고
    • Harnessing HIV for therapy, basic research and biotechnology
    • DOI 10.1016/j.tibtech.2004.11.001, PII S016777990400318X
    • Wiznerowicz, M., and Trono, D. (2005). Harnessing HIV for therapy, basic research and biotechnology. Trends Biotechnol. 23, 42-47. (Pubitemid 40075525)
    • (2005) Trends in Biotechnology , vol.23 , Issue.1 , pp. 42-47
    • Wiznerowicz, M.1    Trono, D.2
  • 113
    • 33645758024 scopus 로고    scopus 로고
    • Transcriptional profiling of reporter genes used for molecular imaging of embryonic stem cell transplantation
    • Wu, J.C., Spin, J.M., Cao, F., et al. (2006). Transcriptional profiling of reporter genes used for molecular imaging of embryonic stem cell transplantation. Physiol, Genomics 25, 29-38.
    • (2006) Physiol, Genomics , vol.25 , pp. 29-38
    • Wu, J.C.1    Spin, J.M.2    Cao, F.3
  • 114
    • 0028705684 scopus 로고
    • Generation of high-titer pseudotyped retroviral vectors with very broad host range
    • Yee, J.K., Friedmann, T., and Burns, J.C. (1994). Generation of high-titer pseudotyped retroviral vectors with very broad host range. Methods Cell Biol. 43(Pt A), 99-112.
    • (1994) Methods Cell Biol. , vol.43 , Issue.PART A , pp. 99-112
    • Yee, J.K.1    Friedmann, T.2    Burns, J.C.3
  • 116
    • 67349202780 scopus 로고    scopus 로고
    • Validation of a mutated PRE sequence allowing high and sustained transgene expression while abrogating WHV-X protein synthesis: Application to the gene therapy of WAS
    • Zanta-Boussif, M.A., Charrier, S., Brice-Ouzet, A., et al. (2009). Validation of a mutated PRE sequence allowing high and sustained transgene expression while abrogating WHV-X protein synthesis: Application to the gene therapy of WAS. Gene Ther. 16, 605-619.
    • (2009) Gene Ther. , vol.16 , pp. 605-619
    • Zanta-Boussif, M.A.1    Charrier, S.2    Brice-Ouzet, A.3
  • 118
    • 0032978712 scopus 로고    scopus 로고
    • Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors
    • Zufferey, R., Donello, J.E., Trono, D., and Hope, T.J. (1999). Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retro-viral vectors. J. Virol. 73, 2886-2892. (Pubitemid 29135675)
    • (1999) Journal of Virology , vol.73 , Issue.4 , pp. 2886-2892
    • Zufferey, R.1    Donello, J.E.2    Trono, D.3    Hope, T.J.4


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