N-glycosylation engineering of biopharmaceutical expression systems

Current Molecular Medicine

Volumn 9, Issue 7, 2009, Pages 774-800

  Jacobs, P P ^a,b,c   Callewaert, N ^a,b  

^a DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^b GHENT UNIVERSITY   (Belgium)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Bacteria; Biopharmaceuticals; Insect cells; Mammalian cell culture; N glycosylation engineering; Plants; Yeast

Indexed keywords

AGALSIDASE BETA; ANTIBODY; ASPARAGINE; BEVACIZUMAB; GLYCAN; GLYCOCONJUGATE; GLYCOPROTEIN; GLYCOSIDASE; GLYCOSYLTRANSFERASE; IMIGLUCERASE; NOVEL ERYTHROPOIESIS STIMULATING PROTEIN; OLIGOSACCHARIDE; POLYPEPTIDE; RECOMBINANT ERYTHROPOIETIN; RECOMBINANT PROTEIN; RITUXIMAB; TISSUE PLASMINOGEN ACTIVATOR; TRASTUZUMAB;

BIOENGINEERING; CAENORHABDITIS ELEGANS; CARBOHYDRATE ANALYSIS; CELL TYPE; COMPLEX FORMATION; DROSOPHILA MELANOGASTER; DRUG HALF LIFE; DRUG INDUSTRY; ENDOPLASMIC RETICULUM; ESCHERICHIA COLI; EUKARYOTE; FUNGAL CELL; GENE EXPRESSION SYSTEM; GLYCOSYLATION; GOLGI COMPLEX; HANSENULA POLYMORPHA; HUMAN; IMMUNOGENICITY; INSECT CELL; LABORATORY; LYSOSOME STORAGE DISEASE; MAMMAL CELL; NONHUMAN; PLANT CELL; PROKARYOTE; PROTEIN EXPRESSION; PROTEIN PROCESSING; REVIEW; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES POMBE; TISSUE DISTRIBUTION;

ANIMALS; BACTERIA; CARBOHYDRATE CONFORMATION; CARBOHYDRATE SEQUENCE; CELL LINE; DRUG INDUSTRY; GLYCOPROTEINS; GLYCOSYLATION; HUMANS; MOLECULAR SEQUENCE DATA; OLIGOSACCHARIDES; PLANTS; POLYSACCHARIDES; PROTEIN ENGINEERING; PROTEIN ISOFORMS; PROTEIN PROCESSING, POST-TRANSLATIONAL; YEASTS;

EUKARYOTA; HEXAPODA; MAMMALIA;

EID: 70350544173     PISSN: 15665240     EISSN: None     Source Type: Journal    
DOI: 10.2174/156652409789105552     Document Type: Review

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