Lentiviral vector delivery of recombinant small interfering RNA expression cassettes

Methods in Enzymology

Volumn 392, Issue , 2005, Pages 218-226

  Li, Ming Jie ^a   Rossi, John J ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

DNA DIRECTED RNA POLYMERASE III; LENTIVIRUS VECTOR; RECOMBINANT RNA; SMALL INTERFERING RNA;

ARTICLE; BRAIN CELL; CELL TYPE; GENE CASSETTE; GENE EXPRESSION; GENE FUNCTION; GENE TARGETING; GENE THERAPY; GENETIC TRANSDUCTION; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; LIVER CELL; MAMMAL CELL; MUSCLE CELL; NONHUMAN; PRIORITY JOURNAL; RNA CLEAVAGE; TARGET CELL; TRANSGENE;

HUMAN IMMUNODEFICIENCY VIRUS; LENTIVIRUS; MAMMALIA;

EID: 11844260706     PISSN: 00766879     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0076-6879(04)92013-7     Document Type: Article

References (13)

1. Arya S.K., Guo C., Josephs S.F., Wong-Staal F. Trans-activator gene of human T-lymphotropic virus type III (HTLV-III). Science. 229:1985;69-73
2. Kafri T., Blomer U., Peterson D.A., Gage F.H., Verma I.M. Sustained expression of genes delivered directly into liver and muscle by lentiviral vectors. Nat. Genet. 17:1997;314-317
3. Lee N.S., Dohjima T., Bauer G., Li H., Li M.J., Ehsani A., Salvaterra P., Rossi J. Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells. Nat. Biotechnol. 20:2002;500-505
4. Li M.-J., Bauer G., Michienzi A., Yee J.-K., Lee N.-S., Kim J., Li S., Castanotto D., Zaia J., Rossi J.J. Inhibition of HIV-1 infection by lentiviral vectors Expressing Pol III promoted anti-HIV RNAs. Mol. Ther. 8:2003;196-206
5. Miller D.G., Adam M.A., Miller A.D. Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection. Mol. Cell. Biol. 10:1990;4239-4242
6. Naldini L., Blomer U., Gage F.H., Trono D., Verma I.M. Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector. Proc. Natl. Acad. Sci. USA. 93:1996;11382-11388
7. Qin X.F., An D.S., Chen I.S., Baltimore D. Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5. Proc. Natl. Acad. Sci. USA. 100:2003;183-188
8. Sastry L., Johnson T., Hobson M.J., Smucker B., Cornetta K. Titering lentiviral vectors: Comparison of DNA, RNA and marker expression methods. Gene. Ther. 9:2002;1155-1162
9. Scherr M., Battmer K., Ganser A., Eder M. Modulation of gene expression by lentiviral-mediated delivery of small interfering RNA. Cell Cycle. 2:2003;251-257
10. Sirven A., Pflumio F., Zennou V., Titeux M., Vainchenker W., Coulombel L., Dubart-Kupperschmitt A., Charneau P. The human immunodeficiency virus type-1 central DNA flap is a crucial determinant for lentiviral vector nuclear import and gene transduction of human hematopoietic stem cells. Blood. 96:2000;4103-4110
11. Uchida N., Sutton R.E., Friera A.M., He D., Reitsma M.J., Chang W.C., Veres G., Scollay R., Weissman I.L. HIV, but not murine leukemia virus, vectors mediate high efficiency gene transfer into freshly isolated G0/G1 human hematopoietic stem cells. Proc. Natl. Acad. Sci. USA. 95:1998;11939-11944
12. Verma I.M. Gene therapy: Hopes, hypes, and hurdles. Mol. Med. 1:1994;2-3
13. Zufferey R., Donello J.E., Trono D., Hope T.J. Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors. J. Virol. 73:1999;2886-2892