메뉴 건너뛰기




Volumn , Issue , 2008, Pages 191-199

Mouse model for Alzheimer's disease

Author keywords

APP; Amyloid peptide; Amyloid plaques; Cognitive deficits; Immunization; Pathology; Tau protein; Therapeutics; Transgenic mice

Indexed keywords


EID: 79958005506     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-1-59745-285-4_22     Document Type: Chapter
Times cited : (1)

References (59)
  • 1
    • 0002270783 scopus 로고
    • Diagnosis
    • Terry RD, Katzman R, Bick KL, Eds. New York: Raven Press
    • Berg L, Morris JC. Diagnosis. In: Terry RD, Katzman R, Bick KL, Eds. Alzheimer Disease. New York: Raven Press, 1994:197-229.
    • (1994) Alzheimer Disease , pp. 197-229
    • Berg, L.1    Morris, J.C.2
  • 12
    • 0027407565 scopus 로고
    • Apolipoprotein E: High-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease
    • Strittmatter WJ, Saunders AM, Schmechel D, Goldgaber D, Roses AD. Apolipoprotein E: High-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc Natl Acad Sci USA 1993;90:1977-1981.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 1977-1981
    • Strittmatter, W.J.1    Saunders, A.M.2    Schmechel, D.3    Goldgaber, D.4    Roses, A.D.5
  • 14
    • 0034515763 scopus 로고    scopus 로고
    • Apolipoprotein e and Alzheimer's disease. A role in amyloid catabolism
    • Poirier J. Apolipoprotein E and Alzheimer's disease. A role in amyloid catabolism. Ann NY Acad Sci 2000;924:81-90.
    • (2000) Ann NY Acad Sci , vol.924 , pp. 81-90
    • Poirier, J.1
  • 15
    • 0026597063 scopus 로고
    • Alzheimer's disease: The amyloid cascade hypothesis
    • Hardy JA, Higgins GA. Alzheimer's disease: The amyloid cascade hypothesis. Science 1992;256:184-185.
    • (1992) Science , vol.256 , pp. 184-185
    • Hardy, J.A.1    Higgins, G.A.2
  • 16
    • 0026743110 scopus 로고
    • Distribution of Alzheimer-type pathologic changes in nondemented elderly individuals matches the pattern in Alzheimer's disease
    • Arriagada PV, Growdon JH, Hedley-Whyte ET, Hyman BT. Distribution of Alzheimer-type pathologic changes in nondemented elderly individuals matches the pattern in Alzheimer's disease. Neurology 1992;42:631-639.
    • (1992) Neurology , vol.42 , pp. 631-639
    • Arriagada, P.V.1    Growdon, J.H.2    Hedley-Whyte, E.T.3    Hyman, B.T.4
  • 18
    • 0027258525 scopus 로고
    • The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: Implications for the pathogenesis of Alzheimer's disease
    • Jarrett JT, Berger EP, Lansbury PT. The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: Implications for the pathogenesis of Alzheimer's disease. Biochemistry 1993;32:4693-4697.
    • (1993) Biochemistry , vol.32 , pp. 4693-4697
    • Jarrett, J.T.1    Berger, E.P.2    Lansbury, P.T.3
  • 21
    • 0032837741 scopus 로고    scopus 로고
    • The levels of soluble versus insoluble brain Abeta distinguish Alzheimer's disease from normal and pathologic aging
    • Wang J, Dickson DW, Trojanowski JQ, Lee VM. The levels of soluble versus insoluble brain Abeta distinguish Alzheimer's disease from normal and pathologic aging. Exp Neurol 1999;158:328-337.
    • (1999) Exp Neurol , vol.158 , pp. 328-337
    • Wang, J.1    Dickson, D.W.2    Trojanowski, J.Q.3    Lee, V.M.4
  • 24
    • 0032214501 scopus 로고    scopus 로고
    • Tau mutations cause frontotemporal dementias
    • Goedert M, Crowther RA, Spillantini MG. Tau mutations cause frontotemporal dementias. Neuron 1998;21:955-958.
    • (1998) Neuron , vol.21 , pp. 955-958
    • Goedert, M.1    Crowther, R.A.2    Spillantini, M.G.3
  • 26
    • 0035066332 scopus 로고    scopus 로고
    • Alzheimer's disease: Genes, proteins, and therapy
    • Selkoe DJ. Alzheimer's disease: Genes, proteins, and therapy. Physiol Rev 2001;81:741-766.
    • (2001) Physiol Rev , vol.81 , pp. 741-766
    • Selkoe, D.J.1
  • 27
    • 0025863618 scopus 로고
    • Neuropathological stageing of Alzheimer-related changes
    • Braak H, Braak E. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol (Berl) 1991;82:239-259.
    • (1991) Acta Neuropathol (Berl) , vol.82 , pp. 239-259
    • Braak, H.1    Braak, E.2
  • 28
    • 0028985574 scopus 로고
    • Alzheimer-type neuropathology in transgenic mice overexpressing V717F [beta]-amyloid precursor protein
    • Games D, Adams D, Alessandrini R, Barbous R, Berthelette P, Blackwell C, et al. Alzheimer-type neuropathology in transgenic mice overexpressing V717F [beta]-amyloid precursor protein. Nature 1995;373:523-527.
    • (1995) Nature , vol.373 , pp. 523-527
    • Games, D.1    Adams, D.2    Alessandrini, R.3    Barbous, R.4    Berthelette, P.5    Blackwell, C.6
  • 29
    • 0029742199 scopus 로고    scopus 로고
    • Correlative memory deficits, A[beta] elevation, and amyloid plaques in transgenic mice
    • Hsaio K, Chapman P, Nilsen S, Eckman C, Harigaya Y, Younkin S, et al. Correlative memory deficits, A[beta] elevation, and amyloid plaques in transgenic mice. Science 1996;274:99-102.
    • (1996) Science , vol.274 , pp. 99-102
    • Hsaio, K.1    Chapman, P.2    Nilsen, S.3    Eckman, C.4    Harigaya, Y.5    Younkin, S.6
  • 33
    • 0035877756 scopus 로고    scopus 로고
    • Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695
    • Chishti MA, Yang D-S, Janus C, Phinney AL, Horne P, Pearson J, et al. Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695. J Biol Chem 2001;276:21562-21570.
    • (2001) J Biol Chem , vol.276 , pp. 21562-21570
    • Chishti, M.A.1    Yang, D.-S.2    Janus, C.3    Phinney, A.L.4    Horne, P.5    Pearson, J.6
  • 34
    • 0034700471 scopus 로고    scopus 로고
    • A[beta] peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease
    • Janus C, Pearson J, McLaurin J, Matthews PM, Jiang Y, Schmidt SD, et al. A[beta] peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease. Nature 2000; 408:979-982.
    • (2000) Nature , vol.408 , pp. 979-982
    • Janus, C.1    Pearson, J.2    McLaurin, J.3    Matthews, P.M.4    Jiang, Y.5    Schmidt, S.D.6
  • 35
    • 16044366039 scopus 로고    scopus 로고
    • Increased amyloid-[beta]42(43) in brains of mice expressing mutant presenilin 1
    • Duff K, Eckman C, Zehr C, Yu X, Prada C-H, Perez-Tur J, et al. Increased amyloid-[beta]42(43) in brains of mice expressing mutant presenilin 1. Nature 1996;383:710-713.
    • (1996) Nature , vol.383 , pp. 710-713
    • Duff, K.1    Eckman, C.2    Zehr, C.3    Yu, X.4    Prada, C.-H.5    Perez-Tur, J.6
  • 36
    • 0031914718 scopus 로고    scopus 로고
    • Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes
    • Holcomb L, Gordon MN, McGowan E, Yu X, Benkovic S, Jantzen P, et al. Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes. Nat Med 1998;4:97-100.
    • (1998) Nat Med , vol.4 , pp. 97-100
    • Holcomb, L.1    Gordon, M.N.2    McGowan, E.3    Yu, X.4    Benkovic, S.5    Jantzen, P.6
  • 37
    • 0037195163 scopus 로고    scopus 로고
    • Neurotoxic effects of thioflavin S-positive amyloid deposits in transgenic mice and Alzheimer's disease
    • Urbanc B, Cruz L, Le R, Sanders J, Hsaio Ashe K, et al. Neurotoxic effects of thioflavin S-positive amyloid deposits in transgenic mice and Alzheimer's disease. Proc Natl Acad Sci USA 2002;99:13990-13995.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 13990-13995
    • Urbanc, B.1    Cruz, L.2    Le, R.3    Sanders, J.4    Hsaio Ashe, K.5
  • 38
    • 0032756213 scopus 로고    scopus 로고
    • Behavioral changes in transgenic mice expressing both amyloid precursor protein and presenilin-1 mutations: Lack of association with amyloid deposits
    • Holcomb L, Gordon MN, Jantzen P, Hsaio K, Duff K, Morgan D. Behavioral changes in transgenic mice expressing both amyloid precursor protein and presenilin-1 mutations: Lack of association with amyloid deposits. Behav Genet 1999;29:177-185.
    • (1999) Behav Genet , vol.29 , pp. 177-185
    • Holcomb, L.1    Gordon, M.N.2    Jantzen, P.3    Hsaio, K.4    Duff, K.5    Morgan, D.6
  • 39
    • 0037088914 scopus 로고    scopus 로고
    • Microglial activation and [beta]-amyloid deposit reduction caused by a nitric oxide-releasing non-steroidal anti-infl ammatory drug in amyloid precursor protein plus presenilin-1 transgenic mice
    • Jantzen PT, Connor KE, DiCarlo G, Wenk GL, Wallace JL, Rojiani AM, et al. Microglial activation and [beta]-amyloid deposit reduction caused by a nitric oxide-releasing non-steroidal anti-infl ammatory drug in amyloid precursor protein plus presenilin-1 transgenic mice. J Neurosci 2002;22:2246-2254.
    • (2002) J Neurosci , vol.22 , pp. 2246-2254
    • Jantzen, P.T.1    Connor, K.E.2    Dicarlo, G.3    Wenk, G.L.4    Wallace, J.L.5    Rojiani, A.M.6
  • 41
    • 0034426011 scopus 로고    scopus 로고
    • Neurofi brillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein
    • Lewis J, McGowan E, Rockwood J, Melrose H, Nacharaju P, et al. Neurofi brillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein. Nat Genet 2000;25:402-405.
    • (2000) Nat Genet , vol.25 , pp. 402-405
    • Lewis, J.1    McGowan, E.2    Rockwood, J.3    Melrose, H.4    Nacharaju, P.5
  • 42
    • 17944382037 scopus 로고    scopus 로고
    • Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP
    • Lewis J, Dickson DW, Lin W-L, Chisholm L, Corral A, Jones G, et al. Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP. Science 2001;293:1487-1491.
    • (2001) Science , vol.293 , pp. 1487-1491
    • Lewis, J.1    Dickson, D.W.2    Lin, W.-L.3    Chisholm, L.4    Corral, A.5    Jones, G.6
  • 43
    • 0035943436 scopus 로고    scopus 로고
    • Formation of neurofi brillary tangles in P301L tau transgenic mice induced by Aβ42 fi brils
    • Götz J, Chen F, Van Dorpe J, Nitsch RM. Formation of neurofi brillary tangles in P301L tau transgenic mice induced by Aβ42 fi brils. Science 2001;293:1491-1495.
    • (2001) Science , vol.293 , pp. 1491-1495
    • Götz, J.1    Chen, F.2    Van Dorpe, J.3    Nitsch, R.M.4
  • 44
    • 0035808361 scopus 로고    scopus 로고
    • Tau filament formation in transgenic mice expressing P301L tau
    • Götz J, Chen F, Barmettler R, Nitsch RM. Tau filament formation in transgenic mice expressing P301L tau. J Biol Chem 2001;276: 529-534.
    • (2001) J Biol Chem , vol.276 , pp. 529-534
    • Götz, J.1    Chen, F.2    Barmettler, R.3    Nitsch, R.M.4
  • 53
    • 0035503597 scopus 로고    scopus 로고
    • The curry spice curcumin reduces oxidative damage and amyloid path ology in an Alzheimer transgenic mouse
    • Lim GP, Chu T, Yang F, Beech W, Frautschy SA, Cole GM. The curry spice curcumin reduces oxidative damage and amyloid path ology in an Alzheimer transgenic mouse. J Neurosci 2001;21:8370-8377.
    • (2001) J Neurosci , vol.21 , pp. 8370-8377
    • Lim, G.P.1    Chu, T.2    Yang, F.3    Beech, W.4    Frautschy, S.A.5    Cole, G.M.6
  • 58
    • 0037088914 scopus 로고    scopus 로고
    • Microglial activation and beta-amyloid deposit reduction caused by a nitric oxide-releasing nonsteroidal anti-inflammatory drug in amyloid precursor protein plus presenilin-1 transgenic mice
    • Jantzen PT, Connor KE, DiCarlo G, Wenk GL, Wallace JL, Rojiani AM, Coppola D, Morgan D, Gordon MN. Microglial activation and beta-amyloid deposit reduction caused by a nitric oxide-releasing nonsteroidal anti-inflammatory drug in amyloid precursor protein plus presenilin-1 transgenic mice. J Neurosci 2002;22:2246-2254.
    • (2002) J Neurosci , vol.22 , pp. 2246-2254
    • Jantzen, P.T.1    Connor, K.E.2    Dicarlo, G.3    Wenk, G.L.4    Wallace, J.L.5    Rojiani, A.M.6    Coppola, D.7    Morgan, D.8    Gordon, M.N.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.