메뉴 건너뛰기




Volumn 18, Issue 15, 2011, Pages 2240-2246

Indoleamine 2,3-dioxygenase, Tregs and cancer

Author keywords

Dendritic cells; Foxp3; IDO; Regulatory T cells; Tumor immunology

Indexed keywords

1 METHYL DEXTRO TRYPTOPHAN; ANTINEOPLASTIC AGENT; B7 ANTIGEN; CANCER VACCINE; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; HALOFUGINONE; HISTONE ACETYLTRANSFERASE; HISTONE ACETYLTRANSFERASE GCN2; INDOLEAMINE 2,3 DIOXYGENASE; INDOLEAMINE 2,3 DIOXYGENASE INHIBITOR; INITIATION FACTOR 2ALPHA; INTERLEUKIN 17; INTERLEUKIN 6; MESSENGER RNA; TRANSCRIPTION FACTOR FOXP3; TRANSFER RNA; TRYPTOPHAN; UNCLASSIFIED DRUG;

EID: 79957936035     PISSN: 09298673     EISSN: 1875533X     Source Type: Journal    
DOI: 10.2174/092986711795656045     Document Type: Article
Times cited : (72)

References (117)
  • 1
    • 37549061827 scopus 로고    scopus 로고
    • Creating immune privilege: Active local suppression that benefits friends, but protects foes
    • Mellor, A.L.; Munn, D.H. Creating immune privilege: active local suppression that benefits friends, but protects foes. Nat. Rev. Immunol., 2008, 8, 74-80.
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 74-80
    • Mellor, A.L.1    Munn, D.H.2
  • 2
    • 34248173331 scopus 로고    scopus 로고
    • Indoleamine 2,3-dioxygenase and tumor-induced tolerance
    • DOI 10.1172/JCI31178
    • Munn, D.H.; Mellor, A.L. Indoleamine 2,3-dioxygenase and tumor-induced tolerance. J. Clin. Invest., 2007, 117, 1147-1154. (Pubitemid 46718399)
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.5 , pp. 1147-1154
    • Munn, D.H.1    Mellor, A.L.2
  • 5
    • 16244408626 scopus 로고    scopus 로고
    • Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy
    • DOI 10.1038/nm1196
    • Muller, A.J.; Duhadaway, J.B.; Donover, P.S.; Sutanto-Ward, E.; Prendergast, G.C. Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy. Nat. Med., 2005, 11, 312-319. (Pubitemid 40460560)
    • (2005) Nature Medicine , vol.11 , Issue.3 , pp. 312-319
    • Muller, A.J.1    DuHadaway, J.B.2    Donover, P.S.3    Sutanto-Ward, E.4    Prendergast, G.C.5
  • 7
    • 0345490963 scopus 로고    scopus 로고
    • Inhibition of Indoleamine 2,3-Dioxygenase Augments Trinitrobenzene Sulfonic Acid Colitis in Mice
    • DOI 10.1053/j.gastro.2003.08.031
    • Gurtner, G.J.; Newberry, R.D.; Schloemann, S.R.; McDonald, K.G.; Stenson, W.F. Inhibition of indoleamine 2,3-dioxygenase augments trinitrobenzene sulfonic acid colitis in mice. Gastroenterology, 2003, 125, 1762-1773. (Pubitemid 37500441)
    • (2003) Gastroenterology , vol.125 , Issue.6 , pp. 1762-1773
    • Gurtner, G.J.1    Newberry, R.D.2    Schloemann, S.R.3    McDonald, K.G.4    Stenson, W.F.5
  • 12
    • 0042591467 scopus 로고    scopus 로고
    • Cutting edge: Induced indoleamine 2,3 dioxygenase expression in dendritic cell subsets suppresses T cell clonal expansion
    • Mellor, A.L.; Baban, B.; Chandler, P.; Marshall, B.; Jhaver, K.; Hansen, A.; Koni, P.A.; Iwashima, M.; Munn, D.H. Cutting Edge: Induced indoleamine 2,3 dioxygenase expression in dendritic cell subsets suppresses T cell clonal expansion. J. Immunol., 2003, 171, 1652-1655. (Pubitemid 36966447)
    • (2003) Journal of Immunology , vol.171 , Issue.4 , pp. 1652-1655
    • Mellor, A.L.1    Baban, B.2    Chandler, P.3    Marshall, B.4    Jhaver, K.5    Hansen, A.6    Koni, P.A.7    Iwashima, M.8    Munn, D.H.9
  • 15
    • 33645123655 scopus 로고    scopus 로고
    • Novel action of indoleamine 2,3-dioxygenase attenuating acute lung allograft injury
    • Liu, H.; Liu, L.; Fletcher, B.S.; Visner, G.A. Novel action of indoleamine 2,3-dioxygenase attenuating acute lung allograft injury. Am. J. Respir. Crit. Care Med., 2006, 173, 566-572.
    • (2006) Am. J. Respir. Crit. Care Med. , vol.173 , pp. 566-572
    • Liu, H.1    Liu, L.2    Fletcher, B.S.3    Visner, G.A.4
  • 18
    • 26444489716 scopus 로고    scopus 로고
    • A minor population of splenic dendritic cells expressing CD19 mediates IDO-dependent T cell suppression via type I IFN signaling following B7 ligation
    • DOI 10.1093/intimm/dxh271
    • Baban, B.; Hansen, A.; Chandler, P.; Manlapat, A.; Bingaman, A.; Kahler, D.; Munn, D.; Mellor, A. A minor population of splenic dendritic cells expressing CD19 mediates IDO-dependent T cell suppression via type 1 interferon-signaling following B7 ligation. Int. Immunol., 2005, 17, 909-919. (Pubitemid 41417958)
    • (2005) International Immunology , vol.17 , Issue.7 , pp. 909-919
    • Baban, B.1    Hansen, A.M.2    Chandler, P.R.3    Manlapat, A.4    Bingaman, A.5    Kahler, D.J.6    Munn, D.H.7    Mellor, A.L.8
  • 19
    • 27144552597 scopus 로고    scopus 로고
    • + dendritic cells to acquire potent indoleamine 2,3-dioxygenase-dependent T cell regulatory functions via IFN type 1 signaling
    • Mellor, A.L.; Baban, B.; Chandler, P.R.; Manlapat, A.; Kahler, D.J.; Munn, D.H. Cutting Edge: CpG oligonucleotides induce splenic CD19+ dendritic cells to acquire potent indoleamine 2,3-dioxygenase-dependent T cell regulatory functions via IFN type 1 signaling. J. Immunol., 2005, 175, 5601-5605. (Pubitemid 41508038)
    • (2005) Journal of Immunology , vol.175 , Issue.9 , pp. 5601-5605
    • Mellor, A.L.1    Baban, B.2    Chandler, P.R.3    Manlapat, A.4    Kahler, D.J.5    Munn, D.H.6
  • 21
    • 71749103051 scopus 로고    scopus 로고
    • Interferon-gamma-responsive nonhematopoietic cells regulate the immune response to Mycobacterium tuberculosis
    • Desvignes, L.; Ernst, J.D. Interferon-gamma-responsive nonhematopoietic cells regulate the immune response to Mycobacterium tuberculosis. Immunity, 2009, 31, 974-985.
    • (2009) Immunity , vol.31 , pp. 974-985
    • Desvignes, L.1    Ernst, J.D.2
  • 22
    • 38449083896 scopus 로고    scopus 로고
    • Induction of indoleamine 2,3-dioxygenase in vascular smooth muscle cells by interferon-gamma contributes to medial immunoprivilege
    • Cuffy, M.C.; Silverio, A.M.; Qin, L.; Wang, Y.; Eid, R.; Brandacher, G.; Lakkis, F.G.; Fuchs, D.; Pober, J.S.; Tellides, G. Induction of indoleamine 2,3-dioxygenase in vascular smooth muscle cells by interferon-gamma contributes to medial immunoprivilege. J Immunol, 2007, 179, 5246-5254.
    • (2007) J Immunol , vol.179 , pp. 5246-5254
    • Cuffy, M.C.1    Silverio, A.M.2    Qin, L.3    Wang, Y.4    Eid, R.5    Brandacher, G.6    Lakkis, F.G.7    Fuchs, D.8    Pober, J.S.9    Tellides, G.10
  • 24
    • 19344377474 scopus 로고    scopus 로고
    • GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase
    • DOI 10.1016/j.immuni.2005.03.013, PII S1074761305001081
    • Munn, D.H.; Sharma, M.D.; Baban, B.; Harding, H.P.; Zhang, Y.; Ron, D.; Mellor, A.L. GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase. Immunity, 2005, 22, 633-642. (Pubitemid 40719198)
    • (2005) Immunity , vol.22 , Issue.5 , pp. 633-642
    • Munn, D.H.1    Sharma, M.D.2    Baban, B.3    Harding, H.P.4    Zhang, Y.5    Ron, D.6    Mellor, A.L.7
  • 25
    • 0034176031 scopus 로고    scopus 로고
    • Indoleamine 2,3-dioxygenase production by human dendritic cells results in the inhibition of T cell proliferation
    • Hwu, P.; Du, M.X.; Lapointe, R.; Do, M.; Taylor, M.W.; Young, H.A. Indoleamine 2,3-dioxygenase production by human dendritic cells results in the inhibition of T cell proliferation. J. Immunol., 2000, 164(7), 3596-3599. (Pubitemid 30169812)
    • (2000) Journal of Immunology , vol.164 , Issue.7 , pp. 3596-3599
    • Hwu, P.1    Du, M.X.2    Lapointe, R.3    Do, M.4    Taylor, M.W.5    Young, H.A.6
  • 28
    • 33644955010 scopus 로고    scopus 로고
    • Function of indoleamine 2,3-dioxygenase in corneal allograft rejection and prolongation of allograft survival by overexpression
    • Beutelspacher, S.C.; Pillai, R.; Watson, M.P.; Tan, P.H.; Tsang, J.; McClure, M.O.; George, A.J.; Larkin, D.F. Function of indoleamine 2,3-dioxygenase in corneal allograft rejection and prolongation of allograft survival by overexpression. Eur. J. Immunol., 2006, 36, 690-700.
    • (2006) Eur. J. Immunol. , vol.36 , pp. 690-700
    • Beutelspacher, S.C.1    Pillai, R.2    Watson, M.P.3    Tan, P.H.4    Tsang, J.5    McClure, M.O.6    George, A.J.7    Larkin, D.F.8
  • 29
    • 27144476792 scopus 로고    scopus 로고
    • A two-step induction of indoleamine 2,3 dioxygenase (IDO) activity during dendritic-cell maturation
    • DOI 10.1182/blood-2005-03-0979
    • Braun, D.; Longman, R.S.; Albert, M.L. A two step induction of indoleamine 2,3 dioxygenase (IDO) activity during dendritic cell maturation. Blood, 2005, 106(7), 2375-2381. (Pubitemid 41510810)
    • (2005) Blood , vol.106 , Issue.7 , pp. 2375-2381
    • Braun, D.1    Longman, R.S.2    Albert, M.L.3
  • 33
    • 68949088471 scopus 로고    scopus 로고
    • Tryptophan deprivation induces inhibitory receptors ILT3 and ILT4 on dendritic cells favoring the induction of human CD4+CD25+ Foxp3+ T regulatory cells
    • Brenk, M.; Scheler, M.; Koch, S.; Neumann, J.; Takikawa, O.; Hacker, G.; Bieber, T.; von Bubnoff, D. Tryptophan deprivation induces inhibitory receptors ILT3 and ILT4 on dendritic cells favoring the induction of human CD4+CD25+ Foxp3+ T regulatory cells. J Immunol, 2009, 183, 145-154.
    • (2009) J Immunol , vol.183 , pp. 145-154
    • Brenk, M.1    Scheler, M.2    Koch, S.3    Neumann, J.4    Takikawa, O.5    Hacker, G.6    Bieber, T.7    Von Bubnoff, D.8
  • 34
    • 33745819629 scopus 로고    scopus 로고
    • Expression of indoleamine 2,3-dioxygenase (IDO) by endothelial cells: Implications for the control of alloresponses
    • DOI 10.1111/j.1600-6143.2006.01324.x
    • Beutelspacher, S.C.; Tan, P.H.; McClure, M.O.; Larkin, D.F.; Lechler, R.I.; George, A.J. Expression of indoleamine 2,3-dioxygenase (IDO) by endothelial cells: implications for the control of alloresponses. Am. J. Transplant. , 2006, 6, 1320-1330. (Pubitemid 44030315)
    • (2006) American Journal of Transplantation , vol.6 , Issue.6 , pp. 1320-1330
    • Beutelspacher, S.C.1    Tan, P.H.2    McClure, M.O.3    Larkin, D.F.P.4    Lechler, R.I.5    George, A.J.T.6
  • 35
    • 34147115208 scopus 로고    scopus 로고
    • + T-cell proliferation by inducing indoleamine 2,3-dioxygenase in plasmacytoid dendritic cells
    • DOI 10.1182/blood-2006-07-034785
    • Boasso, A.; Herbeuval, J.P.; Hardy, A.W.; Anderson, S.A.; Dolan, M.J.; Fuchs, D.; Shearer, G.M. HIV inhibits CD4+ T-cell proliferation by inducing indoleamine 2,3-dioxygenase in plasmacytoid dendritic cells. Blood, 2007, 109, 3351-3359. (Pubitemid 46572523)
    • (2007) Blood , vol.109 , Issue.8 , pp. 3351-3359
    • Boasso, A.1    Herbeuval, J.-P.2    Hardy, A.W.3    Anderson, S.A.4    Dolan, M.J.5    Fuchs, D.6    Shearer, G.M.7
  • 36
    • 70149093957 scopus 로고    scopus 로고
    • Indoleamine 2,3-dioxygenase-expressing mature human monocyte-derived dendritic cells expand potent autologous regulatory T cells
    • Chung, D.J.; Rossi, M.; Romano, E.; Ghith, J.; Yuan, J.; Munn, D.H.; Young, J.W. Indoleamine 2,3-dioxygenase-expressing mature human monocyte-derived dendritic cells expand potent autologous regulatory T cells. Blood, 2009, 114, 555-563.
    • (2009) Blood , vol.114 , pp. 555-563
    • Chung, D.J.1    Rossi, M.2    Romano, E.3    Ghith, J.4    Yuan, J.5    Munn, D.H.6    Young, J.W.7
  • 37
    • 55849140547 scopus 로고    scopus 로고
    • HIV-activated human plasmacytoid DCs induce Tregs through an indoleamine 2,3-dioxygenase-dependent mechanism
    • Manches, O.; Munn, D.; Fallahi, A.; Lifson, J.; Chaperot, L.; Plumas, J.; Bhardwaj, N. HIV-activated human plasmacytoid DCs induce Tregs through an indoleamine 2,3-dioxygenase-dependent mechanism. J. Clin. Invest., 2008, 118, 3431-3439.
    • (2008) J. Clin. Invest. , vol.118 , pp. 3431-3439
    • Manches, O.1    Munn, D.2    Fallahi, A.3    Lifson, J.4    Chaperot, L.5    Plumas, J.6    Bhardwaj, N.7
  • 38
    • 54049151564 scopus 로고    scopus 로고
    • The indoleamine 2,3-dioxygenase pathway is essential for human plasmacytoid dendritic cell-induced adaptive T regulatory cell generation
    • Chen, W.; Liang, X.; Peterson, A.J.; Munn, D.H.; Blazar, B.R. The indoleamine 2,3-dioxygenase pathway is essential for human plasmacytoid dendritic cell-induced adaptive T regulatory cell generation. J. Immunol., 2008, 181, 5396-5404.
    • (2008) J. Immunol. , vol.181 , pp. 5396-5404
    • Chen, W.1    Liang, X.2    Peterson, A.J.3    Munn, D.H.4    Blazar, B.R.5
  • 40
    • 15244359594 scopus 로고    scopus 로고
    • Regulation of human auto- and alloreactive T cells by indoleamine 2,3-dioxygenase (IDO)-producing dendritic cells: Too much ado about IDO?
    • DOI 10.1182/blood-2004-06-2103
    • Terness, P.; Chuang, J.J.; Bauer, T.; Jiga, L.; Opelz, G. Regulation of human auto- and alloreactive T cells by indoleamine 2,3-dioxygenase (IDO)- producing dendritic cells: too much ado about IDO? Blood, 2005, 105, 2480-2486. (Pubitemid 40387049)
    • (2005) Blood , vol.105 , Issue.6 , pp. 2480-2486
    • Terness, P.1    Chuang, J.-J.2    Bauer, T.3    Jiga, L.4    Opelz, G.5
  • 42
    • 1642396607 scopus 로고    scopus 로고
    • + T Cells Triggers Indoleamine 2,3-Dioxygenase Activity in Dendritic Cells
    • Munn, D.H.; Sharma, M.D.; Mellor, A.L. Ligation of B7-1/B7-2 by human CD4+ T cells triggers indoleamine 2,3-dioxygenase activity in dendritic cells. J. Immunol., 2004, 172, 4100-4110. (Pubitemid 38375222)
    • (2004) Journal of Immunology , vol.172 , Issue.7 , pp. 4100-4110
    • Munn, D.H.1    Sharma, M.D.2    Mellor, A.L.3
  • 44
    • 0142137237 scopus 로고    scopus 로고
    • Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase
    • DOI 10.1038/nm934
    • Uyttenhove, C.; Pilotte, L.; Theate, I.; Stroobant, V.; Colau, D.; Parmentier, N.; Boon, T.; Van Den Eynde, B.J. Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3- dioxygenase. Nat. Med., 2003, 9, 1269-1274. (Pubitemid 37279849)
    • (2003) Nature Medicine , vol.9 , Issue.10 , pp. 1269-1274
    • Uyttenhove, C.1    Pilotte, L.2    Theate, I.3    Stroobant, V.4    Colau, D.5    Parmentier, N.6    Boon, T.7    Van Den Eynde, B.J.8
  • 45
    • 67649356699 scopus 로고    scopus 로고
    • Expression of indoleamine 2,3- dioxygenase in metastatic malignant melanoma recruits regulatory T cells to avoid immune detection and affects survival
    • Brody, J.R.; Costantino, C.L.; Berger, A.C.; Sato, T.; Lisanti, M.P.; Yeo, C.J.; Emmons, R.V.; Witkiewicz, A.K. Expression of indoleamine 2,3- dioxygenase in metastatic malignant melanoma recruits regulatory T cells to avoid immune detection and affects survival. Cell Cycle, 2009, 8, 1930-1934.
    • (2009) Cell Cycle , vol.8 , pp. 1930-1934
    • Brody, J.R.1    Costantino, C.L.2    Berger, A.C.3    Sato, T.4    Lisanti, M.P.5    Yeo, C.J.6    Emmons, R.V.7    Witkiewicz, A.K.8
  • 47
    • 43049103779 scopus 로고    scopus 로고
    • Expression of indoleamine 2,3-dioxygenase in metastatic pancreatic ductal adenocarcinoma recruits regulatory T cells to avoid immune detection
    • discussion 854-846
    • Witkiewicz, A.; Williams, T.K.; Cozzitorto, J.; Durkan, B.; Showalter, S.L.; Yeo, C.J.; Brody, J.R. Expression of indoleamine 2,3-dioxygenase in metastatic pancreatic ductal adenocarcinoma recruits regulatory T cells to avoid immune detection. J Am Coll Surg, 2008, 206, 849-854; discussion 854-846.
    • (2008) J Am Coll Surg , vol.206 , pp. 849-854
    • Witkiewicz, A.1    Williams, T.K.2    Cozzitorto, J.3    Durkan, B.4    Showalter, S.L.5    Yeo, C.J.6    Brody, J.R.7
  • 48
    • 64949113986 scopus 로고    scopus 로고
    • Genotyping and expression analysis of IDO2 in human pancreatic cancer: A novel, active target
    • discussion 787-789
    • Witkiewicz, A.K.; Costantino, C.L.; Metz, R.; Muller, A.J.; Prendergast, G.C.; Yeo, C.J.; Brody, J.R. Genotyping and expression analysis of IDO2 in human pancreatic cancer: a novel, active target. J Am Coll Surg, 2009, 208, 781-787; discussion 787-789.
    • (2009) J Am Coll Surg , vol.208 , pp. 781-787
    • Witkiewicz, A.K.1    Costantino, C.L.2    Metz, R.3    Muller, A.J.4    Prendergast, G.C.5    Yeo, C.J.6    Brody, J.R.7
  • 51
    • 58749112572 scopus 로고    scopus 로고
    • Indoleamine 2,3-dioxygenase activity of acute myeloid leukemia cells can be measured from patients' sera by HPLC and is inducible by IFN-gamma
    • Corm, S.; Berthon, C.; Imbenotte, M.; Biggio, V.; Lhermitte, M.; Dupont, C.; Briche, I.; Quesnel, B. Indoleamine 2,3-dioxygenase activity of acute myeloid leukemia cells can be measured from patients' sera by HPLC and is inducible by IFN-gamma. Leuk. Res., 2009, 33, 490-494.
    • (2009) Leuk. Res. , vol.33 , pp. 490-494
    • Corm, S.1    Berthon, C.2    Imbenotte, M.3    Biggio, V.4    Lhermitte, M.5    Dupont, C.6    Briche, I.7    Quesnel, B.8
  • 53
    • 0037024439 scopus 로고    scopus 로고
    • Serum tryptophan decrease correlates with immune activation and impaired quality of life in colorectal cancer
    • DOI 10.1038/sj.bjc.6600336
    • Huang, A.; Fuchs, D.; Widner, B.; Glover, C.; Henderson, D.C.; Allen- Mersh, T.G. Serum tryptophan decrease correlates with immune activation and impaired quality of life in colorectal cancer. Br. J. Cancer, 2002, 86(11), 1691-1696. (Pubitemid 34712909)
    • (2002) British Journal of Cancer , vol.86 , Issue.11 , pp. 1691-1696
    • Huang, A.1    Fuchs, D.2    Widner, B.3    Glover, C.4    Henderson, D.C.5    Allen-Mersh, T.G.6
  • 56
    • 42249084713 scopus 로고    scopus 로고
    • Inverse correlation between tumoral indoleamine 2,3-dioxygenase expression and tumor-infiltrating lymphocytes in endometrial cancer: Its association with disease progression and survival
    • DOI 10.1158/1078-0432.CCR-07-4144
    • Ino, K.; Yamamoto, E.; Shibata, K.; Kajiyama, H.; Yoshida, N.; Terauchi, M.; Nawa, A.; Nagasaka, T.; Takikawa, O.; Kikkawa, F. Inverse correlation between tumoral indoleamine 2,3-dioxygenase expression and tumorinfiltrating lymphocytes in endometrial cancer: its association with disease progression and survival. Clin Cancer Res, 2008, 14, 2310-2317. (Pubitemid 351551062)
    • (2008) Clinical Cancer Research , vol.14 , Issue.8 , pp. 2310-2317
    • Ino, K.1    Yamamoto, E.2    Shibata, K.3    Kajiyama, H.4    Yoshida, N.5    Terauchi, M.6    Nawa, A.7    Nagasaka, T.8    Takikawa, O.9    Kikkawa, F.10
  • 59
    • 0028179056 scopus 로고
    • Role of bone marrow-derived cells in presenting MHC class I-restricted tumor antigens
    • Huang, A.Y.; Golumbek, P.; Ahmadzadeh, M.; Jaffee, E.; Pardoll, D.; Levitsky, H. Role of bone marrow-derived cells in presenting MHC class Irestricted tumor antigens. Science, 1994, 264, 961-965. (Pubitemid 24196166)
    • (1994) Science , vol.264 , Issue.5161 , pp. 961-965
    • Huang, A.Y.C.1    Golumbek, P.2    Ahmadzadeh, M.3    Jaffee, E.4    Pardoll, D.5    Levitsky, H.6
  • 60
    • 0035883073 scopus 로고    scopus 로고
    • Cross-presentation of tumor antigens by bone marrow-derived antigen-presenting cells is the dominant mechanism in the induction of T-cell tolerance during B-cell lymphoma progression
    • Sotomayor, E.M.; Borrello, I.; Rattis, F.M.; Cuenca, A.G.; Abrams, J.; Staveley-O'Carroll, K.; Levitsky, H.I. Cross-presentation of tumor antigens by bone marrow-derived antigen-presenting cells is the dominant mechanism in the induction of T-cell tolerance during B-cell lymphoma progression. Blood, 2001, 98(4), 1070-1077.
    • (2001) Blood , vol.98 , Issue.4 , pp. 1070-1077
    • Sotomayor, E.M.1    Borrello, I.2    Rattis, F.M.3    Cuenca, A.G.4    Abrams, J.5    Staveley-O'Carroll, K.6    Levitsky, H.I.7
  • 65
    • 51049108540 scopus 로고    scopus 로고
    • Limited tumor infiltration by activated T effector cells restricts the therapeutic activity of regulatory T cell depletion against established melanoma
    • Quezada, S.A.; Peggs, K.S.; Simpson, T.R.; Shen, Y.; Littman, D.R.; Allison, J.P. Limited tumor infiltration by activated T effector cells restricts the therapeutic activity of regulatory T cell depletion against established melanoma. J Exp Med, 2008, 205, 2125-2138.
    • (2008) J Exp Med , vol.205 , pp. 2125-2138
    • Quezada, S.A.1    Peggs, K.S.2    Simpson, T.R.3    Shen, Y.4    Littman, D.R.5    Allison, J.P.6
  • 67
    • 44749092510 scopus 로고    scopus 로고
    • Regulatory T cells and treatment of cancer
    • Curiel, T.J. Regulatory T cells and treatment of cancer. Curr. Opin. Immunol., 2008, 20, 241-246.
    • (2008) Curr. Opin. Immunol. , vol.20 , pp. 241-246
    • Curiel, T.J.1
  • 68
    • 0030035226 scopus 로고    scopus 로고
    • Cooperative role of interferon regulatory factor 1 and p91 (STAT1) response elements in interferon-γ-inducible expression of human indoleamine 2,3-dioxygenase gene
    • DOI 10.1074/jbc.271.29.17247
    • Chon, S.Y.; Hassanain, H.H.; Gupta, S.L. Cooperative role of interferon regulatory factor 1 and p91 (STAT1) response elements in intereron-α- inducible expression of human indoleamine 2,3-dioxygenase gene. J. Biol. Chem., 1996, 271, 17247-17252. (Pubitemid 26244281)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.29 , pp. 17247-17252
    • Chon, S.Y.1    Hassanain, H.H.2    Gupta, S.L.3
  • 69
    • 0025222683 scopus 로고
    • Regulation of indoleamine 2,3-dioxygenase gene expression in human fibroblasts by interferon-α
    • Dai, W.; Gupta, S.L. Regulation of indoleamine 2,3-dioxygenase gene expression in human fibroblasts by interferon-α. The Journal of Biological Chemistry, 1990, 265, 19871-19877.
    • (1990) The Journal of Biological Chemistry , vol.265 , pp. 19871-19877
    • Dai, W.1    Gupta, S.L.2
  • 71
  • 72
    • 20144368637 scopus 로고    scopus 로고
    • Dendritic cells have the option to express IDO-mediated suppression or not [4]
    • DOI 10.1182/blood-2005-01-0122
    • Munn, D.H.; Mellor, A.L.; Rossi, M.; Young, J.W. Dendritic cells have the option to express IDO-mediated suppression or not. Blood, 2005, 105, 2618. (Pubitemid 40387070)
    • (2005) Blood , vol.105 , Issue.6 , pp. 2618
    • Munn, D.H.1    Mellor, A.L.2    Rossi, M.3    Young, J.W.4
  • 75
    • 34748835898 scopus 로고    scopus 로고
    • IDO and regulatory T cells: A role for reverse signalling and non-canonical NF-κB activation
    • DOI 10.1038/nri2163, PII NRI2163
    • Puccetti, P.; Grohmann, U. IDO and regulatory T cells: a role for reverse signalling and non-canonical NF-kappaB activation. Nat. Rev. Immunol., 2007, 7, 817-823. (Pubitemid 47480306)
    • (2007) Nature Reviews Immunology , vol.7 , Issue.10 , pp. 817-823
    • Puccetti, P.1    Grohmann, U.2
  • 79
    • 39549096220 scopus 로고    scopus 로고
    • Indoleamine 2,3-dioxygenase-expressing dendritic cells are involved in the generation of CD4+CD25+ regulatory T cells in Peyer's patches in an orally tolerized, collagen-induced arthritis mouse model
    • Park, M.J.; Min, S.Y.; Park, K.S.; Cho, Y.G.; Cho, M.L.; Jung, Y.O.; Park, H.S.; Chang, S.H.; Cho, S.G.; Min, J.K.; Park, S.H.; Kim, H.Y. Indoleamine 2,3-dioxygenase-expressing dendritic cells are involved in the generation of CD4+CD25+ regulatory T cells in Peyer's patches in an orally tolerized, collagen-induced arthritis mouse model. Arthritis Res. Ther., 2008, 10, R11.
    • (2008) Arthritis Res. Ther. , vol.10
    • Park, M.J.1    Min, S.Y.2    Park, K.S.3    Cho, Y.G.4    Cho, M.L.5    Jung, Y.O.6    Park, H.S.7    Chang, S.H.8    Cho, S.G.9    Min, J.K.10    Park, S.H.11    Kim, H.Y.12
  • 81
    • 70350433798 scopus 로고    scopus 로고
    • Interferongamma- triggered indoleamine 2,3-dioxygenase competence in human monocyte-derived dendritic cells induces regulatory activity in allogeneic T cells
    • Jurgens, B.; Hainz, U.; Fuchs, D.; Felzmann, T.; Heitger, A. Interferongamma- triggered indoleamine 2,3-dioxygenase competence in human monocyte-derived dendritic cells induces regulatory activity in allogeneic T cells. Blood, 2009, 114, 3235-3243.
    • (2009) Blood , vol.114 , pp. 3235-3243
    • Jurgens, B.1    Hainz, U.2    Fuchs, D.3    Felzmann, T.4    Heitger, A.5
  • 82
    • 33646239606 scopus 로고    scopus 로고
    • Tumor-induced expansion of regulatory T cells by conversion of CD4+CD25- lymphocytes is thymus and proliferation independent
    • Valzasina, B.; Piconese, S.; Guiducci, C.; Colombo, M.P. Tumor-induced expansion of regulatory T cells by conversion of CD4+CD25- lymphocytes is thymus and proliferation independent. Cancer Res., 2006, 66(8), 4488-4495.
    • (2006) Cancer Res. , vol.66 , Issue.8 , pp. 4488-4495
    • Valzasina, B.1    Piconese, S.2    Guiducci, C.3    Colombo, M.P.4
  • 83
    • 48249147441 scopus 로고    scopus 로고
    • Programmed death 1 ligand signaling regulates the generation of adaptive Foxp3+CD4+ regulatory T cells
    • Wang, L.; Pino-Lagos, K.; de Vries, V.C.; Guleria, I.; Sayegh, M.H.; Noelle, R.J. Programmed death 1 ligand signaling regulates the generation of adaptive Foxp3+CD4+ regulatory T cells. Proc Natl Acad Sci U S A, 2008, 105, 9331-9336.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 9331-9336
    • Wang, L.1    Pino-Lagos, K.2    De Vries, V.C.3    Guleria, I.4    Sayegh, M.H.5    Noelle, R.J.6
  • 84
    • 33846913897 scopus 로고    scopus 로고
    • Natural regulatory T cells and de novo-induced regulatory T cells contribute independently to tumor-specific tolerance
    • Zhou, G.; Levitsky, H.I. Natural regulatory T cells and de novo-induced regulatory T cells contribute independently to tumor-specific tolerance. J. Immunol., 2007, 178, 2155-2162. (Pubitemid 46233413)
    • (2007) Journal of Immunology , vol.178 , Issue.4 , pp. 2155-2162
    • Zhou, G.1    Levitsky, H.I.2
  • 85
    • 14044257258 scopus 로고    scopus 로고
    • + regulatory T cells
    • Wang, H.Y.; Peng, G.; Guo, Z.; Shevach, E.M.; Wang, R.F. Recognition of a new ARTC1 peptide ligand uniquely expressed in tumor cells by antigenspecific CD4+ regulatory T cells. J. Immunol., 2005, 174(5), 2661-2670. (Pubitemid 40279680)
    • (2005) Journal of Immunology , vol.174 , Issue.5 , pp. 2661-2670
    • Wang, H.Y.1    Peng, G.2    Guo, Z.3    Shevach, E.M.4    Wang, R.-F.5
  • 88
  • 89
    • 77649220954 scopus 로고    scopus 로고
    • Mechanisms underlying lineage commitment and plasticity of helper cd4+ t cells
    • O'Shea, J.J.; Paul, W.E. Mechanisms Underlying Lineage Commitment and Plasticity of Helper CD4+ T Cells. Science, 2010, 327, 1098-1102.
    • (2010) Science , vol.327 , pp. 1098-1102
    • O'Shea, J.J.1    Paul, W.E.2
  • 90
    • 34247271308 scopus 로고    scopus 로고
    • Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3
    • DOI 10.1038/ni1437, PII NI1437
    • Williams, L.M.; Rudensky, A.Y. Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3. Nat Immunol, 2007, 8, 277-284. (Pubitemid 46745377)
    • (2007) Nature Immunology , vol.8 , Issue.3 , pp. 277-284
    • Williams, L.M.1    Rudensky, A.Y.2
  • 92
    • 65549115862 scopus 로고    scopus 로고
    • Plasticity of CD4+ T cell lineage differentiation
    • Zhou, L.; Chong, M.M.; Littman, D.R. Plasticity of CD4+ T cell lineage differentiation. Immunity, 2009, 30, 646-655.
    • (2009) Immunity , vol.30 , pp. 646-655
    • Zhou, L.1    Chong, M.M.2    Littman, D.R.3
  • 93
    • 65449125930 scopus 로고    scopus 로고
    • Natural treg cells spontaneously differentiate into pathogenic helper cells in lymphopenic conditions
    • Duarte, J.H.; Zelenay, S.; Bergman, M.L.; Martins, A.C.; Demengeot, J. Natural Treg cells spontaneously differentiate into pathogenic helper cells in lymphopenic conditions. Eur. J. Immunol., 2009, 39, 948-955.
    • (2009) Eur. J. Immunol. , vol.39 , pp. 948-955
    • Duarte, J.H.1    Zelenay, S.2    Bergman, M.L.3    Martins, A.C.4    Demengeot, J.5
  • 94
    • 60549115770 scopus 로고    scopus 로고
    • Heterogeneity of natural Foxp3+ T cells: A committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity
    • Komatsu, N.; Mariotti-Ferrandiz, M.E.; Wang, Y.; Malissen, B.; Waldmann, H.; Hori, S. Heterogeneity of natural Foxp3+ T cells: a committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity. Proc. Natl. Acad. Sci. USA, 2009, 106, 1903-1908.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 1903-1908
    • Komatsu, N.1    Mariotti-Ferrandiz, M.E.2    Wang, Y.3    Malissen, B.4    Waldmann, H.5    Hori, S.6
  • 99
    • 67650351923 scopus 로고    scopus 로고
    • Indoleamine 2,3-dioxygenase controls conversion of Foxp3+ Tregs to TH17-like cells in tumor-draining lymph nodes
    • Sharma, M.D.; Hou, D.Y.; Liu, Y.; Koni, P.A.; Metz, R.; Chandler, P.; Mellor, A.L.; He, Y.; Munn, D.H. Indoleamine 2,3-dioxygenase controls conversion of Foxp3+ Tregs to TH17-like cells in tumor-draining lymph nodes. Blood, 2009, 113, 6102-6111.
    • (2009) Blood , vol.113 , pp. 6102-6111
    • Sharma, M.D.1    Hou, D.Y.2    Liu, Y.3    Koni, P.A.4    Metz, R.5    Chandler, P.6    Mellor, A.L.7    He, Y.8    Munn, D.H.9
  • 100
    • 0037436119 scopus 로고    scopus 로고
    • + T cell-mediated suppression by dendritic cells
    • DOI 10.1126/science.1078231
    • Pasare, C.; Medzhitov, R. Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells. Science, 2003, 299, 1033-1036. (Pubitemid 36222922)
    • (2003) Science , vol.299 , Issue.5609 , pp. 1033-1036
    • Pasare, C.1    Medzhitov, R.2
  • 101
    • 34547643025 scopus 로고    scopus 로고
    • Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophan
    • DOI 10.1158/0008-5472.CAN-07-1872
    • Metz, R.; Duhadaway, J.B.; Kamasani, U.; Laury-Kleintop, L.; Muller, A.J.; Prendergast, G.C. Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophan. Cancer Res, 2007, 67, 7082-7087. (Pubitemid 47206533)
    • (2007) Cancer Research , vol.67 , Issue.15 , pp. 7082-7087
    • Metz, R.1    DuHadaway, J.B.2    Kamasani, U.3    Laury-Kleintop, L.4    Muller, A.J.5    Prendergast, G.C.6
  • 102
    • 32544446451 scopus 로고    scopus 로고
    • Coping with stress: EIF2 kinases and translational control
    • Wek, R.C.; Jiang, H.Y.; Anthony, T.G. Coping with stress: eIF2 kinases and translational control. Biochem. Soc. Trans., 2006, 34, 7-11. (Pubitemid 43235522)
    • (2006) Biochemical Society Transactions , vol.34 , Issue.1 , pp. 7-11
    • Wek, R.C.1    Jiang, H.-Y.2    Anthony, T.G.3
  • 103
    • 0033634654 scopus 로고    scopus 로고
    • Regulated translation initiation controls stress-induced gene expression in mammalian cells
    • Harding, H.P.; Novoa, I.; Zhang, Y.; Zeng, H.; Wek, R.; Schapira, M.; Ron, D. Regulated translation initiation controls stress-induced gene expression in mammalian cells. Mol. Cell., 2000, 6(5), 1099-1108.
    • (2000) Mol. Cell. , vol.6 , Issue.5 , pp. 1099-1108
    • Harding, H.P.1    Novoa, I.2    Zhang, Y.3    Zeng, H.4    Wek, R.5    Schapira, M.6    Ron, D.7
  • 104
    • 38649086127 scopus 로고    scopus 로고
    • Differential immunosuppressive effect of indoleamine 2,3-dioxygenase (IDO) on primary human CD4+ and CD8+ T cells
    • Forouzandeh, F.; Jalili, R.B.; Germain, M.; Duronio, V.; Ghahary, A. Differential immunosuppressive effect of indoleamine 2,3-dioxygenase (IDO) on primary human CD4+ and CD8+ T cells. Mol Cell Biochem, 2008, 309, 1-7.
    • (2008) Mol Cell Biochem , vol.309 , pp. 1-7
    • Forouzandeh, F.1    Jalili, R.B.2    Germain, M.3    Duronio, V.4    Ghahary, A.5
  • 105
    • 33846933459 scopus 로고    scopus 로고
    • L-arginine availability regulates T-lymphocyte cell-cycle progression
    • DOI 10.1182/blood-2006-06-031856
    • Rodriguez, P.C.; Quiceno, D.G.; Ochoa, A.C. L-arginine availability regulates T-lymphocyte cell-cycle progression. Blood, 2007, 109, 1568-1573. (Pubitemid 46239590)
    • (2007) Blood , vol.109 , Issue.4 , pp. 1568-1573
    • Rodriguez, P.C.1    Quiceno, D.G.2    Ochoa, A.C.3
  • 106
    • 58249098408 scopus 로고    scopus 로고
    • Mouse pancreatic islets are resistant to indoleamine 2,3 dioxygenase-induced general control nonderepressible-2 kinase stress pathway and maintain normal viability and function
    • Jalili, R.B.; Forouzandeh, F.; Moeenrezakhanlou, A.; Rayat, G.R.; Rajotte, R.V.; Uludag, H.; Ghahary, A. Mouse pancreatic islets are resistant to indoleamine 2,3 dioxygenase-induced general control nonderepressible-2 kinase stress pathway and maintain normal viability and function. Am J Pathol, 2009, 174, 196-205.
    • (2009) Am J Pathol , vol.174 , pp. 196-205
    • Jalili, R.B.1    Forouzandeh, F.2    Moeenrezakhanlou, A.3    Rayat, G.R.4    Rajotte, R.V.5    Uludag, H.6    Ghahary, A.7
  • 107
    • 66749143121 scopus 로고    scopus 로고
    • Immunology. Amino acid addiction
    • Blander, J.M.; Amsen, D. Immunology. Amino acid addiction. Science, 2009, 324, 1282-1283.
    • (2009) Science , vol.324 , pp. 1282-1283
    • Blander, J.M.1    Amsen, D.2
  • 111
    • 75749087979 scopus 로고    scopus 로고
    • Dioxin and immune regulation: Emerging role of aryl hydrocarbon receptor in the generation of regulatory T cells
    • Marshall, N.B.; Kerkvliet, N.I. Dioxin and immune regulation: emerging role of aryl hydrocarbon receptor in the generation of regulatory T cells. Ann N Y Acad Sci, 2010, 1183, 25-37.
    • (2010) Ann N y Acad Sci , vol.1183 , pp. 25-37
    • Marshall, N.B.1    Kerkvliet, N.I.2
  • 112
    • 35548950221 scopus 로고    scopus 로고
    • Regulatory T-cell inhibition versus depletion: The right choice in cancer immunotherapy
    • DOI 10.1038/nrc2250, PII NRC2250
    • Colombo, M.P.; Piconese, S. Regulatory-T-cell inhibition versus depletion: the right choice in cancer immunotherapy. Nat Rev Cancer, 2007, 7, 880-887. (Pubitemid 350006256)
    • (2007) Nature Reviews Cancer , vol.7 , Issue.11 , pp. 880-887
    • Colombo, M.P.1    Piconese, S.2
  • 113
    • 33846689594 scopus 로고    scopus 로고
    • Inhibition of indoleamine 2,3-dioxygenase in dendritic cells by stereoisomers of 1-methyl-tryptophan correlates with antitumor responses
    • DOI 10.1158/0008-5472.CAN-06-2925
    • Hou, D.Y.; Muller, A.J.; Sharma, M.D.; Duhadaway, J.B.; Banerjee, T.; Johnson, M.; Mellor, A.L.; Prendergast, G.C.; Munn, D.H. Inhibition of IDO in dendritic cells by stereoisomers of 1-methyl-tryptophan correlates with anti-tumor responses. Cancer Res., 2007, 67, 792-801. (Pubitemid 46192220)
    • (2007) Cancer Research , vol.67 , Issue.2 , pp. 792-801
    • Hou, D.-Y.1    Muller, A.J.2    Sharma, M.D.3    DuHadaway, J.4    Banerjee, T.5    Johnson, M.6    Mellor, A.L.7    Prendergast, G.C.8    Munn, D.H.9
  • 114
    • 77952051391 scopus 로고    scopus 로고
    • Overcoming tumor antigen anergy in human malignancies using the novel indeolamine 2,3-dioxygenase (IDO) enzyme inhibitor, 1-methyl-Dtryptophan (1MT)
    • (meeting abstracts)
    • Soliman, H.H.; Antonia, S.J.; Sullivan, D.; Vanahanian, N.; Link, C. Overcoming tumor antigen anergy in human malignancies using the novel indeolamine 2,3-dioxygenase (IDO) enzyme inhibitor, 1-methyl-Dtryptophan (1MT). J. Clin. Oncol., 2009, 27((meeting abstracts)), 3004.
    • (2009) J. Clin. Oncol. , vol.27 , pp. 3004
    • Soliman, H.H.1    Antonia, S.J.2    Sullivan, D.3    Vanahanian, N.4    Link, C.5
  • 115
    • 33746475270 scopus 로고    scopus 로고
    • Targeting the mechanisms of tumoral immune tolerance with small-molecule inhibitors
    • DOI 10.1038/nrc1929, PII NRC1929
    • Muller, A.J.; Scherle, P.A. Targeting the mechanisms of tumoral immune tolerance with small-molecule inhibitors. Nat. Rev. Cancer, 2006, 6, 613-625. (Pubitemid 44140859)
    • (2006) Nature Reviews Cancer , vol.6 , Issue.8 , pp. 613-625
    • Muller, A.J.1    Scherle, P.A.2
  • 116
    • 77950192174 scopus 로고    scopus 로고
    • Immunotherapeutic suppression of indoleamine 2,3-dioxygenase and tumor growth with ethyl pyruvate
    • Muller, A.J.; Duhadaway, J.B.; Jaller, D.; Curtis, P.; Metz, R.; Prendergast, G.C. Immunotherapeutic suppression of indoleamine 2,3-dioxygenase and tumor growth with ethyl pyruvate. Cancer Res., 2010, 70, 1845-1853.
    • (2010) Cancer Res. , vol.70 , pp. 1845-1853
    • Muller, A.J.1    Duhadaway, J.B.2    Jaller, D.3    Curtis, P.4    Metz, R.5    Prendergast, G.C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.