New 1,4-di-N-oxide-quinoxaline-2-ylmethylene isonicotinic acid hydrazide derivatives as anti-Mycobacterium tuberculosis agents

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 12, 2011, Pages 3699-3703

  Torres, Enrique ^a   Moreno, Elsa ^a   Ancizu, Saioa ^a   Barea, Carlos ^a   Galiano, Silvia ^a   Aldana, Ignacio ^a   Monge, Antonio ^a   Pérez Silanes, Silvia ^a  

^a UNIVERSITY OF NAVARRA   (Spain)

Author keywords

Anti tuberculosis agents; Druglikeness; Isoniazid; Microwave assisted synthesis; Quinoxaline 1,4 di N oxide derivatives

Indexed keywords

1,4 DI N OXIDE QUINOXALINE 2 YLMETHYLENE ISONICOTINIC ACID HYDRAZIDE DERIVATIVE; ISONIAZID; ISONIAZID DERIVATIVE; QUINOXALINE DERIVATIVE; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL STRAIN; CYTOTOXICITY; DRUG SCREENING; DRUG SYNTHESIS; HYBRIDIZATION; HYDROGEN BOND; MOLECULAR WEIGHT; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; STRUCTURE ACTIVITY RELATION; VERO CELL;

ANIMALS; ANTI-BACTERIAL AGENTS; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; HYDRAZINES; INHIBITORY CONCENTRATION 50; ISONICOTINIC ACIDS; MOLECULAR STRUCTURE; MYCOBACTERIUM TUBERCULOSIS; QUINOXALINES; VERO CELLS;

MYCOBACTERIUM TUBERCULOSIS;

EID: 79957861504     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.04.072     Document Type: Article

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