Isoniazid is not a lead compound for its pyridyl ring derivatives, isonicotinoyl amides, hydrazides, and hydrazones: A critical review

Current Medicinal Chemistry

Volumn 13, Issue 18, 2006, Pages 2205-2219

  Scior, T ^a   Garces Eisele S J ^b,c  

^a BENEMÉRITA UNIVERSIDAD AUTÓNOMA DE PUEBLA   (Mexico)

^b UNIVERSIDAD DE LAS AMÉRICAS PUEBLA   (Mexico)

^c Laboratorios Clinicos de Puebla   (Mexico)

Author keywords

Hydrazides; Hydrazones; Hydrolysis; Isoniazid; Mycobacterium; QSAR; Tuberculosis

Indexed keywords

ACETONE HYDRAZONE; AMPICILLIN; BENSERAZIDE; BETA LACTAM ANTIBIOTIC; CARBIDOPA; CEPHALOSPORIN DERIVATIVE; CHLORAMPHENICOL; DIHYDRALAZINE; ERYTHROMYCIN; ETHAMBUTOL; HYDRALAZINE; HYDRAZIDE DERIVATIVE; HYDRAZONE DERIVATIVE; IPRONIAZID; ISOCARBOXAZID; ISONIAZID; ISONIAZID DERIVATIVE; ISONICOTINAMIDE; ISONICOTINIC ACID; NOVOBIOCIN; PENICILLIN DERIVATIVE; PROCARBAZINE; PYRAZINAMIDE; PYRIDOXAL BENZOYLHYDRAZONE; PYRIDOXAL ISONICOTINOYLHYDRAZONE; RIFAMPICIN; SALICYL ISONICOTINOYLHYDRAZONE; SALICYLALDEHYDE BENZOYLHYDRAZONE; TRIPAMIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; DRUG ACETYLATION; DRUG EFFICACY; DRUG ELIMINATION; DRUG HALF LIFE; DRUG HYDROLYSIS; DRUG METABOLISM; DRUG POTENCY; DRUG SOLUBILITY; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TRANSFORMATION; HUMAN; IN VITRO STUDY; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR SIZE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REVIEW; SUBSTITUTION REACTION;

AMIDES; ANTITUBERCULAR AGENTS; CELL MEMBRANE PERMEABILITY; DRUG DESIGN; DRUG INDUSTRY; DRUG STABILITY; ENZYMES; HYDROLYSIS; ISONIAZID; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33746496066     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986706777935249     Document Type: Review

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