Selective activity against Mycobacterium tuberculosis of new quinoxaline 1,4-di-N-oxides

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 1, 2009, Pages 385-389

  Vicente, Esther ^a   Pérez Silanes, Silvia ^a   Lima, Lidia M ^b   Ancizu, Saioa ^a   Burguete, Asunción ^a   Solano, Beatriz ^a   Villar, Raquel ^a   Aldana, Ignacio ^a   Monge, Antonio ^a  

^a UNIVERSITY OF NAVARRA   (Spain)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

Antimycobacterial; N Oxide; Quinoxaline; Tuberculosis

Indexed keywords

3 PHENYLQUINOXALINE 1,4 DI N OXIDE DERIVATIVE; 7 METHYL 3 (4' FLUORO)PHENYLQUINOXALINE 2 CARBONITRILE 1,4 DI N OXIDE; QUINOXALINE DERIVATIVE; RIFAMPICIN; UNCLASSIFIED DRUG; FLUORINE; TUBERCULOSTATIC AGENT;

ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ARTICLE; DRUG CYTOTOXICITY; DRUG POTENCY; DRUG SELECTIVITY; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; DRUG EFFECT; HUMAN; MICROBIOLOGICAL EXAMINATION; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

MYCOBACTERIUM TUBERCULOSIS;

ANTITUBERCULAR AGENTS; FLUORINE; HUMANS; MICROBIAL SENSITIVITY TESTS; MYCOBACTERIUM TUBERCULOSIS; QUINOXALINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 57649196329     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.10.086     Document Type: Article

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