Synthesis andanti-mycobacterial evaluation of some pyrazine-2-carboxylic acid hydrazide derivatives

European Journal of Medicinal Chemistry

Volumn 45, Issue 8, 2010, Pages 3384-3388

  Abdel Aziz, Mohamed ^a   Bdel Rahman, Hamdy M A ^b  

^a Minia University   (Egypt)

^b University of Assiut   (Egypt)

Author keywords

Hydrazones; Pyrazinamide; Thiosemicarbazides; Tuberculosis

Indexed keywords

(2 CHLORO 6 METHOXYQUINOLIN 3 YLMETHYLENE)PYRAZINE 2 CARBOXYLIC ACID HYDRAZIDE; (2 CHLORO 6 METHYLQUINOLIN 3 YLMETHYLENE)PYRAZINE 2 CARBOXYLIC ACID HYDRAZIDE; 1 (PHENYLETHYLIDENE)PYRAZINE 2 CARBOXYLIC ACID HYDRAZIDE; 2 HYDROXYBENZYLIDENEPYRAZINE 2 CARBOXYLIC ACID HYDRAZIDE; 3 AMINOBENZYLIDENEPYRAZINE 2 CARBOXYLIC ACID HYDRAZIDE; 3 HYDROXYBENZYLIDENEPYRAZINE 2 CARBOXYLIC ACID HYDRAZIDE; 4 CHLOROBENZYLIDENEPYRAZINE 2 CARBOXYLIC ACID HYDRAZIDE; 4 HYDROXY 3 METHOXYBENZYLIDENEPYRAZINE 2 CARBOXYLIC ACID HYDRAZIDE; 4 HYDROXYBENZYLIDENEPYRAZINE 2 CARBOXYLIC ACID HYDRAZIDE; 4 METHOXYBENZYLIDENEPYRAZINE 2 CARBOXYLIC ACID HYDRAZIDE; HYDRAZIDE DERIVATIVE; N ETHYL N' (PYRAZINE 2 CARBONYL)THIOSEMICARBAZIDE; PYRAZINAMIDE; PYRAZINE 2 CARBOXYLIC ACID HYDRAZIDE DERIVATIVE; UNCLASSIFIED DRUG; [1 (4 BROMOPHENYLETHYLIDENE]PYRAZINE 2 CARBOXYLIC ACID HYDRAZIDE; [1 (4 METHOXYPHENYLETHYLIDENE]PYRAZINE 2 CARBOXYLIC ACID HYDRAZIDE; ANTIINFECTIVE AGENT; HYDRAZINE; HYDRAZINE DERIVATIVE; PYRAZINE 2 CARBOXYLIC ACID HYDRAZIDE; PYRAZINE DERIVATIVE; PYRAZINE-2-CARBOXYLIC ACID HYDRAZIDE;

ANTIMICROBIAL ACTIVITY; ARTICLE; CYTOTOXICITY; DRUG SCREENING; DRUG SYNTHESIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; STRUCTURE ACTIVITY RELATION; ANIMAL; CERCOPITHECUS; CHEMISTRY; DRUG EFFECT; SYNTHESIS; VERO CELL;

ANIMALS; ANTI-BACTERIAL AGENTS; CERCOPITHECUS AETHIOPS; HYDRAZINES; MYCOBACTERIUM TUBERCULOSIS; PYRAZINES; STRUCTURE-ACTIVITY RELATIONSHIP; VERO CELLS;

EID: 77954310135     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2010.04.025     Document Type: Article

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