New 3-methylquinoxaline-2-carboxamide 1,4-di-N-oxide derivatives as anti-Mycobacterium tuberculosis agents

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 7, 2010, Pages 2713-2719

  Ancizu, Saioa ^a   Moreno, Elsa ^a   Solano, Beatriz ^a   Villar, Raquel ^a   Burguete, Asunción ^a   Torres, Enrique ^a   Pérez Silanes, Silvia ^a   Aldana, Ignacio ^a   Monge, Antonio ^a  

^a UNIVERSITY OF NAVARRA   (Spain)

Author keywords

Anti tuberculosis agents; Mycobacterium tuberculosis (M.Tb.); Quinoxaline 1,4 di N oxide derivatives; Rifampin

Indexed keywords

1,4 DI N OXIDE 3 METHYL 7 TRIFLUOROMETHYLQUINOXALINE 2 CARBOXYLIC ACID 2 BENZYLAMIDE; 1,4 DI N OXIDE 3 METHYL 7 TRIFLUOROMETHYLQUINOXALINE 2 CARBOXYLIC ACID 2 PHENYLETHYLAMIDE; 6,7 DICHLORO 1,4 DI N OXIDE 3 METHYLQUINOXALINE 2 CARBOXYLIC ACID 2 BENZYLAMIDE; 6,7 DICHLORO 1,4 DI N OXIDE 3 METHYLQUINOXALINE 2 CARBOXYLIC ACID 2 PHENYLETHYLAMIDE; AMIDE; ANTIMYCOBACTERIAL AGENT; QUINOXALINE DERIVATIVE; RIFAMPICIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG POTENCY; DRUG SCREENING; DRUG SELECTIVITY; DRUG SYNTHESIS; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; STRUCTURE ACTIVITY RELATION; TUBERCULOSIS;

ANIMALS; ANTITUBERCULAR AGENTS; CERCOPITHECUS AETHIOPS; CHROMATOGRAPHY, THIN LAYER; HUMANS; INDICATORS AND REAGENTS; MAGNETIC RESONANCE SPECTROSCOPY; MICROBIAL SENSITIVITY TESTS; MYCOBACTERIUM TUBERCULOSIS; QUINOXALINES; SPECTROPHOTOMETRY, INFRARED; SPECTROPHOTOMETRY, ULTRAVIOLET; STRUCTURE-ACTIVITY RELATIONSHIP; TUBERCULOSIS; VERO CELLS;

MYCOBACTERIUM TUBERCULOSIS;

EID: 77950031328     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.02.024     Document Type: Article

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