-
1
-
-
33645455490
-
Metabonomic strategy for the investigation of the mode of action of the phytotoxin (5S,8R,13S,16R)-(-)-pyrenophorol using H nuclear magnetic resonance fingerprinting
-
Aliferis K.A., Chrysayi-Tokousbalides M. Metabonomic strategy for the investigation of the mode of action of the phytotoxin (5S,8R,13S,16R)-(-)-pyrenophorol using H nuclear magnetic resonance fingerprinting. J. Agric. Food Chem. 2005, 54:1687-1692.
-
(2005)
J. Agric. Food Chem.
, vol.54
, pp. 1687-1692
-
-
Aliferis, K.A.1
Chrysayi-Tokousbalides, M.2
-
2
-
-
0038699591
-
High-throughput classification of yeast mutants for functional genomics using metabolic footprinting
-
Allen J., Davey H.M., Broadhurst D., Heald J.K., Rowland J.J., Oliver S.G., Kell D.B. High-throughput classification of yeast mutants for functional genomics using metabolic footprinting. Nat. Biotechnol. 2003, 21:692-696.
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 692-696
-
-
Allen, J.1
Davey, H.M.2
Broadhurst, D.3
Heald, J.K.4
Rowland, J.J.5
Oliver, S.G.6
Kell, D.B.7
-
3
-
-
8144230574
-
Discrimination of modes of action of antifungal substances by use of metabolic footprinting
-
Allen J., Davey H.M., Broadhurst D., Rowland J.J., Oliver S.G., Kell D.B. Discrimination of modes of action of antifungal substances by use of metabolic footprinting. Appl. Environ. Microbiol. 2004, 70:6157-6165.
-
(2004)
Appl. Environ. Microbiol.
, vol.70
, pp. 6157-6165
-
-
Allen, J.1
Davey, H.M.2
Broadhurst, D.3
Rowland, J.J.4
Oliver, S.G.5
Kell, D.B.6
-
4
-
-
67650027307
-
Lipidomic analysis of endocannabinoid metabolism in biological samples
-
Astarita G., Piomelli D. Lipidomic analysis of endocannabinoid metabolism in biological samples. J. Chromatogr. B 2009, 877:2755-2767.
-
(2009)
J. Chromatogr. B
, vol.877
, pp. 2755-2767
-
-
Astarita, G.1
Piomelli, D.2
-
5
-
-
0033947573
-
19F-NMR to analyze the mode of action and the metabolism of the herbicide isoxaflutole
-
19F-NMR to analyze the mode of action and the metabolism of the herbicide isoxaflutole. Plant Physiol. Biochem. 2000, 38:517-523.
-
(2000)
Plant Physiol. Biochem.
, vol.38
, pp. 517-523
-
-
Aubert, S.1
Pallett, K.E.2
-
6
-
-
42949089041
-
Capillary electrophoresis-Fourier transform ion cyclotron resonance mass spectrometry for the identification of cationic metabolites via a pH-mediated stacking-transient isotachophoretic method
-
Baidoo E.E.K., Benke P.I., Neusuess C., Pelzing M., Kruppa G., Leary J.A., Keasling J.D. Capillary electrophoresis-Fourier transform ion cyclotron resonance mass spectrometry for the identification of cationic metabolites via a pH-mediated stacking-transient isotachophoretic method. Anal. Chem. 2008, 80:3112-3122.
-
(2008)
Anal. Chem.
, vol.80
, pp. 3112-3122
-
-
Baidoo, E.E.K.1
Benke, P.I.2
Neusuess, C.3
Pelzing, M.4
Kruppa, G.5
Leary, J.A.6
Keasling, J.D.7
-
7
-
-
21144441213
-
Spatial tissue distribution of polyacetylenes in carrot root
-
Baranska M., Schulz H. Spatial tissue distribution of polyacetylenes in carrot root. Analyst 2005, 130:855-859.
-
(2005)
Analyst
, vol.130
, pp. 855-859
-
-
Baranska, M.1
Schulz, H.2
-
8
-
-
0142039110
-
NMR-based metabonomic toxicity classification: hierarchical cluster analysis and k-nearest-neighbour approaches
-
Beckonert O., Bollard M.E., Ebbels T.M.D., Keun H.C., Antti H., Holmes E., Lindon J.C., Nicholson J.K. NMR-based metabonomic toxicity classification: hierarchical cluster analysis and k-nearest-neighbour approaches. Anal. Chim. Acta 2003, 490:3-15.
-
(2003)
Anal. Chim. Acta
, vol.490
, pp. 3-15
-
-
Beckonert, O.1
Bollard, M.E.2
Ebbels, T.M.D.3
Keun, H.C.4
Antti, H.5
Holmes, E.6
Lindon, J.C.7
Nicholson, J.K.8
-
9
-
-
41049099137
-
Current and emerging mass-spectrometry technologies for metabolomics
-
Bedair M., Sumner L.W. Current and emerging mass-spectrometry technologies for metabolomics. Trends Anal. Chem. 2008, 27:238-250.
-
(2008)
Trends Anal. Chem.
, vol.27
, pp. 238-250
-
-
Bedair, M.1
Sumner, L.W.2
-
10
-
-
30744460897
-
Large-scale human metabolomics studies: a strategy for data (pre-)processing and validation
-
Bijlsma S., Bobeldijk I., Verheij E.R., Ramaker R., Kochhar S., Macdonald I.A., Van Ommen B., Smilde A.K. Large-scale human metabolomics studies: a strategy for data (pre-)processing and validation. Anal. Chem. 2006, 78:567-574.
-
(2006)
Anal. Chem.
, vol.78
, pp. 567-574
-
-
Bijlsma, S.1
Bobeldijk, I.2
Verheij, E.R.3
Ramaker, R.4
Kochhar, S.5
Macdonald, I.A.6
Van Ommen, B.7
Smilde, A.K.8
-
11
-
-
11344249260
-
Metabolome analysis: the potential of in vivo labeling with stable isotopes for metabolite profiling
-
Birkemeyer C., Luedemann A., Wagner C., Erban A., Kopka J. Metabolome analysis: the potential of in vivo labeling with stable isotopes for metabolite profiling. Trends Biotechnol. 2005, 23:28-33.
-
(2005)
Trends Biotechnol.
, vol.23
, pp. 28-33
-
-
Birkemeyer, C.1
Luedemann, A.2
Wagner, C.3
Erban, A.4
Kopka, J.5
-
12
-
-
0022385560
-
Comparison of the urinary metabolite profile of caffeine in young and elderly males
-
Blanchard J., Sawers S.J., Jonkman J.H., Tang-Liu D.D. Comparison of the urinary metabolite profile of caffeine in young and elderly males. Br. J. Clin. Pharmacol. 1985, 19:225-232.
-
(1985)
Br. J. Clin. Pharmacol.
, vol.19
, pp. 225-232
-
-
Blanchard, J.1
Sawers, S.J.2
Jonkman, J.H.3
Tang-Liu, D.D.4
-
13
-
-
27144450537
-
Systems biology. Less is more in modeling large genetic networks
-
Bornholdt S. Systems biology. Less is more in modeling large genetic networks. Science 2005, 310:449-451.
-
(2005)
Science
, vol.310
, pp. 449-451
-
-
Bornholdt, S.1
-
15
-
-
1942422633
-
Metabolomic analysis of adrenal lipids during hypoxia in the neonatal rat: Implications in steroidogenesis
-
Bruder E.D., Lee P.C., Raff H. Metabolomic analysis of adrenal lipids during hypoxia in the neonatal rat: Implications in steroidogenesis. Am. J. Physiol. Endocrinol. Metab. 2004, 286:E697-E703.
-
(2004)
Am. J. Physiol. Endocrinol. Metab.
, vol.286
-
-
Bruder, E.D.1
Lee, P.C.2
Raff, H.3
-
16
-
-
0035968112
-
An NMR-based metabonomic approach to the investigation of coelomic fluid biochemistry in earthworms under toxic stress
-
Bundy J.G., Osborn D., Weeks J.M., Lindon J.C., Nicholson J.K. An NMR-based metabonomic approach to the investigation of coelomic fluid biochemistry in earthworms under toxic stress. FEBS Lett. 2001, 500:31-35.
-
(2001)
FEBS Lett.
, vol.500
, pp. 31-35
-
-
Bundy, J.G.1
Osborn, D.2
Weeks, J.M.3
Lindon, J.C.4
Nicholson, J.K.5
-
17
-
-
0036707692
-
Metabonomic assessment of toxicity of 4-fluoroaniline, 3,5-difluoroaniline and 2-fluoro-4-methylaniline to the earthworm Eisenia veneta (Rosa): Identification of new endogenous biomarkers
-
Bundy J.G., Lenz E.M., Bailey N.J., Gavaghan C.L., Svendsen C., Spurgeon D., Hankard P.K., Osborn D., Weeks J.M., Trauger S.A. Metabonomic assessment of toxicity of 4-fluoroaniline, 3,5-difluoroaniline and 2-fluoro-4-methylaniline to the earthworm Eisenia veneta (Rosa): Identification of new endogenous biomarkers. Environ. Toxicol. Chem. 2002, 21:1966-1972.
-
(2002)
Environ. Toxicol. Chem.
, vol.21
, pp. 1966-1972
-
-
Bundy, J.G.1
Lenz, E.M.2
Bailey, N.J.3
Gavaghan, C.L.4
Svendsen, C.5
Spurgeon, D.6
Hankard, P.K.7
Osborn, D.8
Weeks, J.M.9
Trauger, S.A.10
-
18
-
-
0036307203
-
Metabolism of 4-fluoroaniline and 4-fluoro-biphenyl in the earthworm Eisenia veneta characterized by high-resolution NMR spectroscopy with directly coupled HPLC-NMR and HPLC-MS
-
Bundy J.G., Lenz E.M., Osborn D., Weeks J.M., Lindon J.C., Nicholson J.K. Metabolism of 4-fluoroaniline and 4-fluoro-biphenyl in the earthworm Eisenia veneta characterized by high-resolution NMR spectroscopy with directly coupled HPLC-NMR and HPLC-MS. Xenobiotica 2002, 32:479-490.
-
(2002)
Xenobiotica
, vol.32
, pp. 479-490
-
-
Bundy, J.G.1
Lenz, E.M.2
Osborn, D.3
Weeks, J.M.4
Lindon, J.C.5
Nicholson, J.K.6
-
19
-
-
45449111362
-
"Systems toxicology" approach identifies coordinated metabolic responses to copper in a terrestrial non-model invertebrate, the earthworm Lumbricus rubellus
-
Bundy J.G., Sidhu J.K., Rana F., Spurgeon D.J., Svendsen C., Wren J.F., Stürzenbaum S.R., Morgan A.J., Kille P. "Systems toxicology" approach identifies coordinated metabolic responses to copper in a terrestrial non-model invertebrate, the earthworm Lumbricus rubellus. BMC Biol. 2008, 6:25.
-
(2008)
BMC Biol.
, vol.6
, pp. 25
-
-
Bundy, J.G.1
Sidhu, J.K.2
Rana, F.3
Spurgeon, D.J.4
Svendsen, C.5
Wren, J.F.6
Stürzenbaum, S.R.7
Morgan, A.J.8
Kille, P.9
-
20
-
-
61849165638
-
Environmental metabolomics: a critical review and future perspectives
-
Bundy J.G., Davey M.P., Viant M.R. Environmental metabolomics: a critical review and future perspectives. Metabolomics 2009, 5:3-21.
-
(2009)
Metabolomics
, vol.5
, pp. 3-21
-
-
Bundy, J.G.1
Davey, M.P.2
Viant, M.R.3
-
21
-
-
64649089947
-
Cross-platform comparison of methods for quantitative metabolomics of primary metabolism
-
Buscher J.M., Czernik D., Ewald J.C., Sauer U., Zamboni N. Cross-platform comparison of methods for quantitative metabolomics of primary metabolism. Anal. Chem. 2009, 81:2135-2143.
-
(2009)
Anal. Chem.
, vol.81
, pp. 2135-2143
-
-
Buscher, J.M.1
Czernik, D.2
Ewald, J.C.3
Sauer, U.4
Zamboni, N.5
-
22
-
-
34250164588
-
Chemoselective probes for metabolite enrichment and profiling
-
Carlson E.E., Cravatt B.F. Chemoselective probes for metabolite enrichment and profiling. Nat. Methods 2007, 4:429-435.
-
(2007)
Nat. Methods
, vol.4
, pp. 429-435
-
-
Carlson, E.E.1
Cravatt, B.F.2
-
23
-
-
37549027670
-
Enrichment tags for enhanced-resolution profiling of the polar metabolome
-
Carlson E.E., Cravatt B.F. Enrichment tags for enhanced-resolution profiling of the polar metabolome. J. Am. Chem. Soc. 2007, 129:15780-15782.
-
(2007)
J. Am. Chem. Soc.
, vol.129
, pp. 15780-15782
-
-
Carlson, E.E.1
Cravatt, B.F.2
-
24
-
-
26444548613
-
Hierarchical metabolomics demonstrates substantial compositional similarity between genetically modified and conventional potato crops
-
Catchpole G.S., Beckmann M., Enot D.P., Mondhe M., Zywicki B., Taylor J., Hardy N., Smith A., King R.D., Kell D.B., Fiehn O., Draper J. Hierarchical metabolomics demonstrates substantial compositional similarity between genetically modified and conventional potato crops. Proc. Natl. Acad. Sci. USA 2005, 102:14458-14462.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 14458-14462
-
-
Catchpole, G.S.1
Beckmann, M.2
Enot, D.P.3
Mondhe, M.4
Zywicki, B.5
Taylor, J.6
Hardy, N.7
Smith, A.8
King, R.D.9
Kell, D.B.10
Fiehn, O.11
Draper, J.12
-
25
-
-
60249102576
-
Challenges and developments in tandem mass spectrometry based clinical metabolomics
-
Ceglarek U., Leichtle A., Brugel M., Kortz L., Brauer R., Bresler K., Thiery J., Fiedler G.M. Challenges and developments in tandem mass spectrometry based clinical metabolomics. Mol. Cell. Endocrinol. 2009, 301:266-271.
-
(2009)
Mol. Cell. Endocrinol.
, vol.301
, pp. 266-271
-
-
Ceglarek, U.1
Leichtle, A.2
Brugel, M.3
Kortz, L.4
Brauer, R.5
Bresler, K.6
Thiery, J.7
Fiedler, G.M.8
-
26
-
-
55249122149
-
Direct profiling and imaging of plant metabolites in intact tissues by using colloidal graphite-assisted laser desorption ionization mass spectrometry
-
Cha S.W., Zhang H., Ilarslan H.I., Wurtele E.S., Brachova L., Nikolau B.J., Yeung E.S. Direct profiling and imaging of plant metabolites in intact tissues by using colloidal graphite-assisted laser desorption ionization mass spectrometry. Plant J. 2008, 55:348-360.
-
(2008)
Plant J.
, vol.55
, pp. 348-360
-
-
Cha, S.W.1
Zhang, H.2
Ilarslan, H.I.3
Wurtele, E.S.4
Brachova, L.5
Nikolau, B.J.6
Yeung, E.S.7
-
28
-
-
44349165818
-
Shotgun lipidomics reveals the temporally dependent, highly diversified cardiolipin profile in the mammalian brain: Temporally coordinated postnatal diversification of cardiolipin molecular species with neuronal remodelling
-
Cheng H., Mancuso D.J., Jiang X.T., Guan S.P., Yang J.Y., Yang K., Sun G., Gross R.W., Han X.L. Shotgun lipidomics reveals the temporally dependent, highly diversified cardiolipin profile in the mammalian brain: Temporally coordinated postnatal diversification of cardiolipin molecular species with neuronal remodelling. Biochemistry 2008, 47:5869-5880.
-
(2008)
Biochemistry
, vol.47
, pp. 5869-5880
-
-
Cheng, H.1
Mancuso, D.J.2
Jiang, X.T.3
Guan, S.P.4
Yang, J.Y.5
Yang, K.6
Sun, G.7
Gross, R.W.8
Han, X.L.9
-
29
-
-
35349030199
-
Raman spectroscopy-based metabolomics for differentiating exposures to triazole fungicides using rat urine
-
Cherney D.P., Ekman D.R., Dix D.J., Collette T.W. Raman spectroscopy-based metabolomics for differentiating exposures to triazole fungicides using rat urine. Anal. Chem. 2007, 79:7324-7332.
-
(2007)
Anal. Chem.
, vol.79
, pp. 7324-7332
-
-
Cherney, D.P.1
Ekman, D.R.2
Dix, D.J.3
Collette, T.W.4
-
30
-
-
20444387276
-
Hyphenation of solid-phase extraction with liquid chromatography and nuclear magnetic resonance: application of HPLC-DAD-SPE-NMR to identification of constituents of Kanahia laniflora
-
Clarkson C., Staerk D., Hansen S.H., Jaroszewski J.W. Hyphenation of solid-phase extraction with liquid chromatography and nuclear magnetic resonance: application of HPLC-DAD-SPE-NMR to identification of constituents of Kanahia laniflora. Anal. Chem. 2005, 77:3547-3553.
-
(2005)
Anal. Chem.
, vol.77
, pp. 3547-3553
-
-
Clarkson, C.1
Staerk, D.2
Hansen, S.H.3
Jaroszewski, J.W.4
-
31
-
-
0037348405
-
An integrated metabonomic investigation of acetaminophen toxicity in the mouse using NMR spectroscopy
-
Coen M., Lenz E.M., Nicholson J.K., Wilson I.D., Pognan F., Lindon J.C. An integrated metabonomic investigation of acetaminophen toxicity in the mouse using NMR spectroscopy. Chem. Res. Toxicol. 2003, 16:295-303.
-
(2003)
Chem. Res. Toxicol.
, vol.16
, pp. 295-303
-
-
Coen, M.1
Lenz, E.M.2
Nicholson, J.K.3
Wilson, I.D.4
Pognan, F.5
Lindon, J.C.6
-
32
-
-
1642345498
-
Integrated application of transcriptomics and metabonomics yields new insight into the toxicity due to paracetamol in the mouse
-
Coen M., Ruepp S.U., Lindon J.C., Nicholson J.K., Pognan F., Lenz E.M., Wilson I.D. Integrated application of transcriptomics and metabonomics yields new insight into the toxicity due to paracetamol in the mouse. J. Pharm. Biomed. Anal. 2004, 35:93-105.
-
(2004)
J. Pharm. Biomed. Anal.
, vol.35
, pp. 93-105
-
-
Coen, M.1
Ruepp, S.U.2
Lindon, J.C.3
Nicholson, J.K.4
Pognan, F.5
Lenz, E.M.6
Wilson, I.D.7
-
33
-
-
0034523338
-
Comparative metabolism of chloroacetamide herbicides and selected metabolites in human and rat liver microsomes
-
Coleman S., Linderman R., Hodgson E., Rose R.L. Comparative metabolism of chloroacetamide herbicides and selected metabolites in human and rat liver microsomes. Environ. Health Perspect. 2000, 108:1151-1157.
-
(2000)
Environ. Health Perspect.
, vol.108
, pp. 1151-1157
-
-
Coleman, S.1
Linderman, R.2
Hodgson, E.3
Rose, R.L.4
-
34
-
-
58949099722
-
Lipidomic approaches to measuring isoprostanes and other markers of oxidative stress
-
Davies S.D. Lipidomic approaches to measuring isoprostanes and other markers of oxidative stress. Eur. J. Lipid Sci. Technol. 2009, 111:64-74.
-
(2009)
Eur. J. Lipid Sci. Technol.
, vol.111
, pp. 64-74
-
-
Davies, S.D.1
-
35
-
-
84882807503
-
Metabolomics
-
Wiley, Hoboken, NJ, R.C. Smart, E. Hodgson (Eds.)
-
Deighton N. Metabolomics. Molecular and Biochemical Toxicology 2008, 67-80. Wiley, Hoboken, NJ. 4th ed. R.C. Smart, E. Hodgson (Eds.).
-
(2008)
Molecular and Biochemical Toxicology
, pp. 67-80
-
-
Deighton, N.1
-
37
-
-
16244402990
-
Metabolomics: Current analytical platforms and methodologies
-
Dunn W.B., Ellis D.I. Metabolomics: Current analytical platforms and methodologies. Trend Anal. Chem. 2005, 24:285-294.
-
(2005)
Trend Anal. Chem.
, vol.24
, pp. 285-294
-
-
Dunn, W.B.1
Ellis, D.I.2
-
38
-
-
33746911582
-
Metabolomic evaluation of rat liver and testis to characterize the toxicity of triazole fungicides
-
Ekman D.R., Keun H.C., Eads C.D., Furnish C.M., Murrell R.N., Rockett J.C., Dix D.J. Metabolomic evaluation of rat liver and testis to characterize the toxicity of triazole fungicides. Metabolomics 2006, 2:63-73.
-
(2006)
Metabolomics
, vol.2
, pp. 63-73
-
-
Ekman, D.R.1
Keun, H.C.2
Eads, C.D.3
Furnish, C.M.4
Murrell, R.N.5
Rockett, J.C.6
Dix, D.J.7
-
39
-
-
34848869926
-
NMR analysis of male fathead minnow urinary metabolites: a potential approach for studying impacts of chemical exposures
-
Ekman D.R., Teng Q., Jensen K.M., Martinovic D., Villeneuve D.L., Ankley G.T., Collette T.W. NMR analysis of male fathead minnow urinary metabolites: a potential approach for studying impacts of chemical exposures. Aquat. Toxicol. 2007, 85:104-112.
-
(2007)
Aquat. Toxicol.
, vol.85
, pp. 104-112
-
-
Ekman, D.R.1
Teng, Q.2
Jensen, K.M.3
Martinovic, D.4
Villeneuve, D.L.5
Ankley, G.T.6
Collette, T.W.7
-
40
-
-
0034959944
-
Combining genomics, metabolome analysis, and biochemical modeling to understand metabolic networks
-
Fiehn O. Combining genomics, metabolome analysis, and biochemical modeling to understand metabolic networks. Comp. Funct. Genom. 2001, 2:155-168.
-
(2001)
Comp. Funct. Genom.
, vol.2
, pp. 155-168
-
-
Fiehn, O.1
-
41
-
-
0036007687
-
Metabolomics - The link between genotypes and phenotypes
-
Fiehn O. Metabolomics - The link between genotypes and phenotypes. Plant Mol. Biol. 2002, 48:155-171.
-
(2002)
Plant Mol. Biol.
, vol.48
, pp. 155-171
-
-
Fiehn, O.1
-
42
-
-
0034254574
-
Identification of uncommon plant metabolites based on calculation of elemental compositions using gas chromatography and quadrupole mass spectrometry
-
Fiehn O., Kopka J., Trethewey R.N., Willmitzer L. Identification of uncommon plant metabolites based on calculation of elemental compositions using gas chromatography and quadrupole mass spectrometry. Anal. Chem. 2000, 72:3573-3580.
-
(2000)
Anal. Chem.
, vol.72
, pp. 3573-3580
-
-
Fiehn, O.1
Kopka, J.2
Trethewey, R.N.3
Willmitzer, L.4
-
43
-
-
34748838949
-
The metabolomics standards initiative (MSI)
-
Fiehn O., Robertson D., Griffin J., van der Werf M., Nikolau B., Morrison N., et al. The metabolomics standards initiative (MSI). Metabolomics 2007, 3:175-178.
-
(2007)
Metabolomics
, vol.3
, pp. 175-178
-
-
Fiehn, O.1
Robertson, D.2
Griffin, J.3
van der Werf, M.4
Nikolau, B.5
Morrison, N.6
-
44
-
-
0035029632
-
1H NMR and magic angle spinning NMR spectroscopic investigation of the biochemical effects of 2-bromoethanamine in intact renal and hepatic tissue
-
1H NMR and magic angle spinning NMR spectroscopic investigation of the biochemical effects of 2-bromoethanamine in intact renal and hepatic tissue. Magn. Reson. Med. 2001, 45:781-790.
-
(2001)
Magn. Reson. Med.
, vol.45
, pp. 781-790
-
-
Garrod, S.1
Humpher, E.2
Connor, S.C.3
Connelly, J.C.4
Spraul, M.5
Nicholson, J.K.6
Holmes, E.7
-
45
-
-
1942470073
-
Metabolomics by numbers: acquiring and understanding global metabolite data
-
Goodacre R., Vaidyanathan S., Dunn W.B., Harrigan G.G., Kell D.B. Metabolomics by numbers: acquiring and understanding global metabolite data. Trends Biotechnol. 2004, 22:245-251.
-
(2004)
Trends Biotechnol.
, vol.22
, pp. 245-251
-
-
Goodacre, R.1
Vaidyanathan, S.2
Dunn, W.B.3
Harrigan, G.G.4
Kell, D.B.5
-
46
-
-
34748839546
-
Proposed minimum reporting standards for data analysis in metabolomics
-
Goodacre R., Broadhurst D., Smilde A.K., Kristal B.S., Baker J.D., Beger R., et al. Proposed minimum reporting standards for data analysis in metabolomics. Metabolomics 2007, 3:231-241.
-
(2007)
Metabolomics
, vol.3
, pp. 231-241
-
-
Goodacre, R.1
Broadhurst, D.2
Smilde, A.K.3
Kristal, B.S.4
Baker, J.D.5
Beger, R.6
-
47
-
-
0142138236
-
Metabonomics: NMR spectroscopy and pattern recognition analysis of body fluids and tissues for characterisation of xenobiotic toxicity and disease diagnosis
-
Griffin J.L. Metabonomics: NMR spectroscopy and pattern recognition analysis of body fluids and tissues for characterisation of xenobiotic toxicity and disease diagnosis. Curr. Opin. Chem. Biol. 2003, 7:648-654.
-
(2003)
Curr. Opin. Chem. Biol.
, vol.7
, pp. 648-654
-
-
Griffin, J.L.1
-
48
-
-
33847370301
-
Tumour metabolomics in animal models of human cancer
-
Griffin J.L., Kauppinen R.A. Tumour metabolomics in animal models of human cancer. J. Proteome Res. 2006, 6:498-505.
-
(2006)
J. Proteome Res.
, vol.6
, pp. 498-505
-
-
Griffin, J.L.1
Kauppinen, R.A.2
-
50
-
-
1842430173
-
Defining a metabolic phenotype in the brain of a transgenic mouse model of spinocerebellar ataxia 3
-
Griffin J.L., Cemal C.K., Pook M.A. Defining a metabolic phenotype in the brain of a transgenic mouse model of spinocerebellar ataxia 3. Physiol. Genomics 2004, 16:334-340.
-
(2004)
Physiol. Genomics
, vol.16
, pp. 334-340
-
-
Griffin, J.L.1
Cemal, C.K.2
Pook, M.A.3
-
51
-
-
33846205679
-
Monitoring diet effects via biofluids and their implications for metabolomics studies
-
Gu H., Chen H., Pan Z., Jackson A.U., Talaty N., Xi B., Kissinger C., Duda C., Mann D., Raftery D., Cooks R.G. Monitoring diet effects via biofluids and their implications for metabolomics studies. Anal. Chem. 2007, 79:89-97.
-
(2007)
Anal. Chem.
, vol.79
, pp. 89-97
-
-
Gu, H.1
Chen, H.2
Pan, Z.3
Jackson, A.U.4
Talaty, N.5
Xi, B.6
Kissinger, C.7
Duda, C.8
Mann, D.9
Raftery, D.10
Cooks, R.G.11
-
52
-
-
61849146324
-
Validation of metabolomics for toxic mechanism of action screening with the earthworm Lumbricus rubellus.
-
Guo Q., Sidhu J.K., Ebbels T.M.D., Rana F., Spurgeon D.J., Svendsen C., Sturzenbaum S.R., Kille P., Morgan A.J., Bundy J.G. Validation of metabolomics for toxic mechanism of action screening with the earthworm Lumbricus rubellus. Metabolomics 2009, 5:72-83.
-
(2009)
Metabolomics
, vol.5
, pp. 72-83
-
-
Guo, Q.1
Sidhu, J.K.2
Ebbels, T.M.D.3
Rana, F.4
Spurgeon, D.J.5
Svendsen, C.6
Sturzenbaum, S.R.7
Kille, P.8
Morgan, A.J.9
Bundy, J.G.10
-
53
-
-
0346366560
-
Application of high-throughput Fourier-transform infrared spectroscopy in toxicology studies: contribution to a study on the development of an animal model for idiosyncratic toxicity
-
Harrigan G.G., LaPlante R.H., Cosma G.N., Cockerell G., Goodacre R., Maddox J.F., Luyendyk J.P., Ganey P.E., Roth R.A. Application of high-throughput Fourier-transform infrared spectroscopy in toxicology studies: contribution to a study on the development of an animal model for idiosyncratic toxicity. Toxicol. Lett. 2004, 146:197-205.
-
(2004)
Toxicol. Lett.
, vol.146
, pp. 197-205
-
-
Harrigan, G.G.1
LaPlante, R.H.2
Cosma, G.N.3
Cockerell, G.4
Goodacre, R.5
Maddox, J.F.6
Luyendyk, J.P.7
Ganey, P.E.8
Roth, R.A.9
-
54
-
-
34548618455
-
Urinary metabolic fingerprinting for amiodarone-induced phospholipidosis in rats using FT-ICR MS
-
Hasegawa M., Takenaka S., Kuwamura M., Yamate J., Tsuyama S. Urinary metabolic fingerprinting for amiodarone-induced phospholipidosis in rats using FT-ICR MS. Exp. Toxicol. Pathol. 2007, 59:115-120.
-
(2007)
Exp. Toxicol. Pathol.
, vol.59
, pp. 115-120
-
-
Hasegawa, M.1
Takenaka, S.2
Kuwamura, M.3
Yamate, J.4
Tsuyama, S.5
-
55
-
-
0035194774
-
In vitro human phase I metabolism of xenobiotics I: pesticides and related chemicals used in agriculture and public health
-
Hodgson E. In vitro human phase I metabolism of xenobiotics I: pesticides and related chemicals used in agriculture and public health. J. Biochem. Mol. Toxicol. 2001, 15:296-299.
-
(2001)
J. Biochem. Mol. Toxicol.
, vol.15
, pp. 296-299
-
-
Hodgson, E.1
-
56
-
-
67849133745
-
Analytical strategies in lipidomics and applications in disease biomarker discovery
-
Hu C., van der Heijden R., Wang M., van der Greef J., Hankemeier T., Xu G. Analytical strategies in lipidomics and applications in disease biomarker discovery. J. Chromatogr. B 2009, 877:2836-2846.
-
(2009)
J. Chromatogr. B
, vol.877
, pp. 2836-2846
-
-
Hu, C.1
van der Heijden, R.2
Wang, M.3
van der Greef, J.4
Hankemeier, T.5
Xu, G.6
-
57
-
-
41149085180
-
Differential metabolomics using stable isotope labeling and two-dimensional gas chromatography with time-of-flight mass spectrometry
-
Huang X., Regnier F.E. Differential metabolomics using stable isotope labeling and two-dimensional gas chromatography with time-of-flight mass spectrometry. Anal. Chem. 2008, 80:107-114.
-
(2008)
Anal. Chem.
, vol.80
, pp. 107-114
-
-
Huang, X.1
Regnier, F.E.2
-
58
-
-
22244441842
-
An integrated functional genomics and metabolomics approach for defining poor prognosis in human neuroendocrine cancers
-
Ippolito J.E., Xu J., Jain S., Moulder K., Mennerick S., Crowley J.R., Townsend R.R., Gordon J.I. An integrated functional genomics and metabolomics approach for defining poor prognosis in human neuroendocrine cancers. Proc. Natl. Acad. Sci. USA 2005, 102:9901-9906.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 9901-9906
-
-
Ippolito, J.E.1
Xu, J.2
Jain, S.3
Moulder, K.4
Mennerick, S.5
Crowley, J.R.6
Townsend, R.R.7
Gordon, J.I.8
-
61
-
-
46749087881
-
Metabolomic profiling using Orbitrap Fourier transform mass spectrometry with hydrophilic interaction chromatography: a method with wide applicability to analysis of biomolecules
-
Kamleh A., Barrett M.P., Wildridge D., Burchmore R.J.S., Scheltema R.A., Watson D.G. Metabolomic profiling using Orbitrap Fourier transform mass spectrometry with hydrophilic interaction chromatography: a method with wide applicability to analysis of biomolecules. Rapid Commun. Mass Spectrom. 2008, 22:1912-1918.
-
(2008)
Rapid Commun. Mass Spectrom.
, vol.22
, pp. 1912-1918
-
-
Kamleh, A.1
Barrett, M.P.2
Wildridge, D.3
Burchmore, R.J.S.4
Scheltema, R.A.5
Watson, D.G.6
-
62
-
-
33845810018
-
Data correction strategy for metabolomics analysis using gas chromatography-mass spectrometry
-
Kanani H., Klapa M.I. Data correction strategy for metabolomics analysis using gas chromatography-mass spectrometry. Metab. Eng. 2007, 9:39-51.
-
(2007)
Metab. Eng.
, vol.9
, pp. 39-51
-
-
Kanani, H.1
Klapa, M.I.2
-
63
-
-
51849132351
-
Comparative metabolomic analysis of Sinorhizobium sp. C4 during the degradation of phenanthrene
-
Keum Y.S., Seo J.S., Li Q.X., Kim J.H. Comparative metabolomic analysis of Sinorhizobium sp. C4 during the degradation of phenanthrene. Appl. Microbiol. Biotechnol. 2008, 80:863-872.
-
(2008)
Appl. Microbiol. Biotechnol.
, vol.80
, pp. 863-872
-
-
Keum, Y.S.1
Seo, J.S.2
Li, Q.X.3
Kim, J.H.4
-
64
-
-
4644255326
-
Stable isotope labeling of Arabidopsis thaliana for an NMR-based metabolomics approach
-
Kikuchi J., Shinozaki K., Hirayama T. Stable isotope labeling of Arabidopsis thaliana for an NMR-based metabolomics approach. Plant Cell Physiol. 2004, 45:1099-1104.
-
(2004)
Plant Cell Physiol.
, vol.45
, pp. 1099-1104
-
-
Kikuchi, J.1
Shinozaki, K.2
Hirayama, T.3
-
65
-
-
33947216093
-
A comprehensive urinary metabolomic approach for identifying kidney cancer
-
Kind T., Tolstikov V., Fiehn O., Weiss R.H. A comprehensive urinary metabolomic approach for identifying kidney cancer. Anal. Biochem. 2007, 363:185-195.
-
(2007)
Anal. Biochem.
, vol.363
, pp. 185-195
-
-
Kind, T.1
Tolstikov, V.2
Fiehn, O.3
Weiss, R.H.4
-
66
-
-
40649088623
-
Higher mass loadability in comprehensive two-dimensional gas chromatography-mass spectrometry for improved analytical performance in metabolomics analysis
-
Koek M.M., Muilwijk B., van Stee L.L.P., Hankemeier T. Higher mass loadability in comprehensive two-dimensional gas chromatography-mass spectrometry for improved analytical performance in metabolomics analysis. J. Chromatogr. A 2008, 1186:420-429.
-
(2008)
J. Chromatogr. A
, vol.1186
, pp. 420-429
-
-
Koek, M.M.1
Muilwijk, B.2
van Stee, L.L.P.3
Hankemeier, T.4
-
67
-
-
34447562825
-
Noninvasive human metabolome analysis for differential diagnosis of inborn errors of metabolism
-
Kuhara T. Noninvasive human metabolome analysis for differential diagnosis of inborn errors of metabolism. J. Chromatogr. B 2007, 855:42-50.
-
(2007)
J. Chromatogr. B
, vol.855
, pp. 42-50
-
-
Kuhara, T.1
-
68
-
-
28644445655
-
A two-dimensional electrophoresis proteomic reference map and systematic identification of 1367 proteins from a cell suspension culture of the model legume Medicago truncatula
-
Lei Z., Elmer A.M., Watson B.S., Dixon R.A., Mendes P.J., Sumner L.W. A two-dimensional electrophoresis proteomic reference map and systematic identification of 1367 proteins from a cell suspension culture of the model legume Medicago truncatula. Mol. Cell. Proteomics 2006, 4:1812-1825.
-
(2006)
Mol. Cell. Proteomics
, vol.4
, pp. 1812-1825
-
-
Lei, Z.1
Elmer, A.M.2
Watson, B.S.3
Dixon, R.A.4
Mendes, P.J.5
Sumner, L.W.6
-
69
-
-
20344368357
-
1H-NMR spectroscopy for the characterization of endogenous metabolites in earthworms with biochemical biomarker potential
-
1H-NMR spectroscopy for the characterization of endogenous metabolites in earthworms with biochemical biomarker potential. Metabolomics 2005, 1:123-136.
-
(2005)
Metabolomics
, vol.1
, pp. 123-136
-
-
Lenz, E.M.1
Weeks, J.M.2
Lindon, J.C.3
Osborn, D.4
Nicholson, J.K.5
-
70
-
-
41149120469
-
Analytical technologies for metabonomics and metabolomics, and multi-omic information recovery
-
Lindon J.C., Nicholson J.K. Analytical technologies for metabonomics and metabolomics, and multi-omic information recovery. Trends Anal. Chem. 2008, 27:194-204.
-
(2008)
Trends Anal. Chem.
, vol.27
, pp. 194-204
-
-
Lindon, J.C.1
Nicholson, J.K.2
-
71
-
-
66349087823
-
Spectroscopic and statistical techniques for information recovery in metabonomics and metabolomics
-
Lindon J.C., Nicholson J.K. Spectroscopic and statistical techniques for information recovery in metabonomics and metabolomics. Annu. Rev. Anal. Chem. 2008, 1:45-69.
-
(2008)
Annu. Rev. Anal. Chem.
, vol.1
, pp. 45-69
-
-
Lindon, J.C.1
Nicholson, J.K.2
-
72
-
-
0004151258
-
-
Springer-Verlag, New York, pp 16-23
-
Luckner M. Secondary Metabolism in Microorganisms, Plants, and Animals 1990, Springer-Verlag, New York, pp 16-23.
-
(1990)
Secondary Metabolism in Microorganisms, Plants, and Animals
-
-
Luckner, M.1
-
73
-
-
4344654116
-
31P nuclear magnetic resonance spectroscopy
-
31P nuclear magnetic resonance spectroscopy. Planta 2004, 219:661-672.
-
(2004)
Planta
, vol.219
, pp. 661-672
-
-
Lundberg, P.1
Lundquist, P.-O.2
-
74
-
-
0024603174
-
Pesticides effects on secondary metabolism of higher plants
-
Lydon J., Duke S.O. Pesticides effects on secondary metabolism of higher plants. Pestic. Sci. 1988, 25:361-373.
-
(1988)
Pestic. Sci.
, vol.25
, pp. 361-373
-
-
Lydon, J.1
Duke, S.O.2
-
75
-
-
42949111593
-
Direct introduction of biological samples into a LTQ-Orbitrap hybrid mass spectrometer as a tool for fast metabolome analysis
-
Madalinski G., Godat E., Alves S., Lesage D., Genin E., Levi P., Labarre J., Tabet J.-C., Ezan E., Junot C. Direct introduction of biological samples into a LTQ-Orbitrap hybrid mass spectrometer as a tool for fast metabolome analysis. Anal. Chem. 2008, 80:3291-3303.
-
(2008)
Anal. Chem.
, vol.80
, pp. 3291-3303
-
-
Madalinski, G.1
Godat, E.2
Alves, S.3
Lesage, D.4
Genin, E.5
Levi, P.6
Labarre, J.7
Tabet, J.-C.8
Ezan, E.9
Junot, C.10
-
77
-
-
65249146628
-
UPLC-MS-based analysis of human plasma for metabonomics using solvent precipitation or solid phase extraction
-
Michopoulos F., Lai L., Gika H., Theodoridis G., Wilson I. UPLC-MS-based analysis of human plasma for metabonomics using solvent precipitation or solid phase extraction. J. Proteome Res. 2009, 8:2114-2121.
-
(2009)
J. Proteome Res.
, vol.8
, pp. 2114-2121
-
-
Michopoulos, F.1
Lai, L.2
Gika, H.3
Theodoridis, G.4
Wilson, I.5
-
78
-
-
33847356478
-
Environmental metabolomics: A SWOT analysis (strengths, weaknesses, opportunities, and threats)
-
Miller M.G. Environmental metabolomics: A SWOT analysis (strengths, weaknesses, opportunities, and threats). J. Proteome Res. 2007, 6:540-545.
-
(2007)
J. Proteome Res.
, vol.6
, pp. 540-545
-
-
Miller, M.G.1
-
79
-
-
34748869539
-
Standard reporting requirements for biological samples in metabolomics experiments: environmental context
-
Morrison N., Bearden D., Bundy J.G., Collette T., Currie F., Davey M.P., et al. Standard reporting requirements for biological samples in metabolomics experiments: environmental context. Metabolomics 3 2007, 3:203-210.
-
(2007)
Metabolomics 3
, vol.3
, pp. 203-210
-
-
Morrison, N.1
Bearden, D.2
Bundy, J.G.3
Collette, T.4
Currie, F.5
Davey, M.P.6
-
81
-
-
0022261909
-
A high resolution proton nuclear magnetic resonance approach to the study of hepatocyte and drug metabolism. Application to acetaminophen
-
Nicholson J.K., Timbrell J.A., Bales J.R., Sadler P.J. A high resolution proton nuclear magnetic resonance approach to the study of hepatocyte and drug metabolism. Application to acetaminophen. Mol. Pharmacol. 1985, 27:634-643.
-
(1985)
Mol. Pharmacol.
, vol.27
, pp. 634-643
-
-
Nicholson, J.K.1
Timbrell, J.A.2
Bales, J.R.3
Sadler, P.J.4
-
82
-
-
0036463681
-
Metabonomics: A platform for studying drug toxicity and gene function
-
Nicholson J.K., Connelly J., Lindon J.C., Holmes E. Metabonomics: A platform for studying drug toxicity and gene function. Nat. Rev. Drug Discov. 2002, 1:153-161.
-
(2002)
Nat. Rev. Drug Discov.
, vol.1
, pp. 153-161
-
-
Nicholson, J.K.1
Connelly, J.2
Lindon, J.C.3
Holmes, E.4
-
83
-
-
35648961364
-
Metabolic profiling using Fourier-transform ion-cyclotron-resonance mass spectrometry
-
Ohta D., Shibata D., Kanaya S. Metabolic profiling using Fourier-transform ion-cyclotron-resonance mass spectrometry. Anal. Bioanal. Chem. 2007, 389:1469-1475.
-
(2007)
Anal. Bioanal. Chem.
, vol.389
, pp. 1469-1475
-
-
Ohta, D.1
Shibata, D.2
Kanaya, S.3
-
84
-
-
33750055741
-
Clarification of pathway-specific inhibition by Fourier transform ion cyclotron resonance/mass spectrometry-based metabolic fingerprinting studies
-
Oikawa A., Nakamura Y., Ogura T., Kimura A., Suzuki H., Sakurai N., Shinbo Y., Shibata D., Kanaya S., Ohta D. Clarification of pathway-specific inhibition by Fourier transform ion cyclotron resonance/mass spectrometry-based metabolic fingerprinting studies. Plant Physiol. 2006, 142:398-413.
-
(2006)
Plant Physiol.
, vol.142
, pp. 398-413
-
-
Oikawa, A.1
Nakamura, Y.2
Ogura, T.3
Kimura, A.4
Suzuki, H.5
Sakurai, N.6
Shinbo, Y.7
Shibata, D.8
Kanaya, S.9
Ohta, D.10
-
85
-
-
48449090785
-
KEGG Atlas mapping for global analysis of metabolic pathways
-
Okuda S., Yamada T., Hamajima M., Itoh M., Katayama T., Bork P., Goto S., Kanehisa M. KEGG Atlas mapping for global analysis of metabolic pathways. Nucleic Acids Res. 2008, 36(web server):W423-W426.
-
(2008)
Nucleic Acids Res.
, vol.36
, Issue.WEB SERVER
-
-
Okuda, S.1
Yamada, T.2
Hamajima, M.3
Itoh, M.4
Katayama, T.5
Bork, P.6
Goto, S.7
Kanehisa, M.8
-
86
-
-
0032168794
-
Systematic functional analysis of the yeast genome
-
Oliver S.G., Winson M.K., Kell D.B., Baganz F. Systematic functional analysis of the yeast genome. Trends Biotechnol. 1998, 16(9):373-378.
-
(1998)
Trends Biotechnol.
, vol.16
, Issue.9
, pp. 373-378
-
-
Oliver, S.G.1
Winson, M.K.2
Kell, D.B.3
Baganz, F.4
-
87
-
-
60649084394
-
A multi-analytical approach for metabolomic profiling of zebrafish (Danio rerio) livers
-
Ong E.S., Chor C.F., Zou L., Ong C.N. A multi-analytical approach for metabolomic profiling of zebrafish (Danio rerio) livers. Mol. BioSyst. 2009, 5:288-298.
-
(2009)
Mol. BioSyst.
, vol.5
, pp. 288-298
-
-
Ong, E.S.1
Chor, C.F.2
Zou, L.3
Ong, C.N.4
-
88
-
-
0037371851
-
Metabonomics classifies pathways affected by bioactive compounds. Artificial neural network classification of NMR spectra of plant extracts
-
Ott K.H., Araníbar N., Singh B., Stockton G.W. Metabonomics classifies pathways affected by bioactive compounds. Artificial neural network classification of NMR spectra of plant extracts. Phytochemistry 2003, 62:971-985.
-
(2003)
Phytochemistry
, vol.62
, pp. 971-985
-
-
Ott, K.H.1
Araníbar, N.2
Singh, B.3
Stockton, G.W.4
-
89
-
-
48849114188
-
Gas chromatography/mass spectrometry in metabolic profiling of biological fluids
-
Pasikanti K.K., Ho P.C., Chan E.C.Y. Gas chromatography/mass spectrometry in metabolic profiling of biological fluids. J. Chromatogr. B 2008, 871:202-211.
-
(2008)
J. Chromatogr. B
, vol.871
, pp. 202-211
-
-
Pasikanti, K.K.1
Ho, P.C.2
Chan, E.C.Y.3
-
90
-
-
0036388279
-
Use of liquid chromatography/time-of-flight mass spectrometry and multivariate statistical analysis shows promise for the detection of drug metabolites in biological fluids
-
Plumb R.S., Stumpf C.L., Gorenstein M.V., Castro-Perez J.M., Dear G.J., Anthony M., Sweatman B.C., Connor S.C., Haselden J.N. Use of liquid chromatography/time-of-flight mass spectrometry and multivariate statistical analysis shows promise for the detection of drug metabolites in biological fluids. Rapid Commun. Mass Spectrom. 2002, 16:1991-1996.
-
(2002)
Rapid Commun. Mass Spectrom.
, vol.16
, pp. 1991-1996
-
-
Plumb, R.S.1
Stumpf, C.L.2
Gorenstein, M.V.3
Castro-Perez, J.M.4
Dear, G.J.5
Anthony, M.6
Sweatman, B.C.7
Connor, S.C.8
Haselden, J.N.9
-
91
-
-
55349094997
-
Multivariate classification analysis of metabolomic data for candidate biomarker discovery in type 2 diabetes mellitus
-
Qiu Y., Rajagopalan D., Connor S.C., Damian D., Zhu L., Handzel A., Hu G., Amanullah A., Bao S., Woody N., MacLean D., Lee K., Vanderwall D., Ryan T. Multivariate classification analysis of metabolomic data for candidate biomarker discovery in type 2 diabetes mellitus. Metabolomics 2008, 4:337-346.
-
(2008)
Metabolomics
, vol.4
, pp. 337-346
-
-
Qiu, Y.1
Rajagopalan, D.2
Connor, S.C.3
Damian, D.4
Zhu, L.5
Handzel, A.6
Hu, G.7
Amanullah, A.8
Bao, S.9
Woody, N.10
MacLean, D.11
Lee, K.12
Vanderwall, D.13
Ryan, T.14
-
92
-
-
43049167370
-
Development of GCxGC/TOF-MS metabolomics for use in ecotoxicological studies with invertebrates
-
Ralston-Hooper K., Hopf A., Oh C., Zhang X., Adamec J., Sepulveda M.S. Development of GCxGC/TOF-MS metabolomics for use in ecotoxicological studies with invertebrates. Aquat. Toxicol. 2008, 88:48-52.
-
(2008)
Aquat. Toxicol.
, vol.88
, pp. 48-52
-
-
Ralston-Hooper, K.1
Hopf, A.2
Oh, C.3
Zhang, X.4
Adamec, J.5
Sepulveda, M.S.6
-
94
-
-
17844368603
-
Urinary markers of adrenarche: reference values in healthy subjects, aged 3-18 years
-
Remer T., Boye K.R., Hartmann M.F., Wudy S.A. Urinary markers of adrenarche: reference values in healthy subjects, aged 3-18 years. J. Clin. Endocrinol. Metab. 2005, 90:2015-2021.
-
(2005)
J. Clin. Endocrinol. Metab.
, vol.90
, pp. 2015-2021
-
-
Remer, T.1
Boye, K.R.2
Hartmann, M.F.3
Wudy, S.A.4
-
95
-
-
20544466649
-
Metabonomics in toxicology: A review
-
Robertson D.G. Metabonomics in toxicology: A review. Toxicol. Sci. 2005, 85:809-822.
-
(2005)
Toxicol. Sci.
, vol.85
, pp. 809-822
-
-
Robertson, D.G.1
-
96
-
-
61849091454
-
NMR-based metabolomics using earthworms as potential indicators for soil health
-
Rochfort S.J., Ezernieks V., Yen A.L. NMR-based metabolomics using earthworms as potential indicators for soil health. Metabolomics 2009, 5:95-107.
-
(2009)
Metabolomics
, vol.5
, pp. 95-107
-
-
Rochfort, S.J.1
Ezernieks, V.2
Yen, A.L.3
-
97
-
-
33746909835
-
Assessing the performance of statistical validation tools for megavariate metabolomics data
-
Rubingh C.M., Bijlsma S., Derks E.P.P.A., Bobeldijk I., Verheij E.R., Kochhar S., Smilde A.K. Assessing the performance of statistical validation tools for megavariate metabolomics data. Metabolomics 2006, 2:53-61.
-
(2006)
Metabolomics
, vol.2
, pp. 53-61
-
-
Rubingh, C.M.1
Bijlsma, S.2
Derks, E.P.P.A.3
Bobeldijk, I.4
Verheij, E.R.5
Kochhar, S.6
Smilde, A.K.7
-
98
-
-
33745212063
-
Using NMR metabolomics to identify responses of an environmental estrogen in blood plasma of fish
-
Samuelsson L.M., Forlin L., Karlsson G., Adolfsson-Erici M., Larsson D.G.J. Using NMR metabolomics to identify responses of an environmental estrogen in blood plasma of fish. Aquat. Toxicol. 2006, 78:341-349.
-
(2006)
Aquat. Toxicol.
, vol.78
, pp. 341-349
-
-
Samuelsson, L.M.1
Forlin, L.2
Karlsson, G.3
Adolfsson-Erici, M.4
Larsson, D.G.J.5
-
99
-
-
33645698674
-
The early responses of Arabidopsis thaliana cells to cadmium exposure explored by protein and metabolite profiling analyses
-
Sarry J.E., Kuhn L., Ducruix C., Lafaye A., Junot C., Hugouvieux V., Jourdain A., Bastien O., Fievet J.B., Vailhen D., Amekraz B., Moulin C., Ezan E., Garin J., Bourguignon J. The early responses of Arabidopsis thaliana cells to cadmium exposure explored by protein and metabolite profiling analyses. Proteomics 2006, 6:2180-2198.
-
(2006)
Proteomics
, vol.6
, pp. 2180-2198
-
-
Sarry, J.E.1
Kuhn, L.2
Ducruix, C.3
Lafaye, A.4
Junot, C.5
Hugouvieux, V.6
Jourdain, A.7
Bastien, O.8
Fievet, J.B.9
Vailhen, D.10
Amekraz, B.11
Moulin, C.12
Ezan, E.13
Garin, J.14
Bourguignon, J.15
-
100
-
-
33947392610
-
Urine stability for metabolomic studies: effects of preparation and storage.
-
Saude E.J., Sykes B.D. Urine stability for metabolomic studies: effects of preparation and storage. Metabolomics 2007, 3:19-27.
-
(2007)
Metabolomics
, vol.3
, pp. 19-27
-
-
Saude, E.J.1
Sykes, B.D.2
-
101
-
-
65049089975
-
Environmental metabolomics: new insights into earthworm ecotoxicity and contaminant bioavailability in soil
-
Simpson M.J., McKelvie J.R. Environmental metabolomics: new insights into earthworm ecotoxicity and contaminant bioavailability in soil. Anal. Bioanal. Chem. 2009, 394:137-149.
-
(2009)
Anal. Bioanal. Chem.
, vol.394
, pp. 137-149
-
-
Simpson, M.J.1
McKelvie, J.R.2
-
102
-
-
33750584707
-
Proteomics and metabolomics: The molecular make-up of toxic aromatic pollutant bioremediation
-
Singh O.V. Proteomics and metabolomics: The molecular make-up of toxic aromatic pollutant bioremediation. Proteomics 2006, 6:5481-5492.
-
(2006)
Proteomics
, vol.6
, pp. 5481-5492
-
-
Singh, O.V.1
-
103
-
-
0002301232
-
Metabonomic applications in toxicity screening and disease diagnosis
-
Shockcor J.P., Holmes E. Metabonomic applications in toxicity screening and disease diagnosis. Curr. Top. Med. Chem. 2002, 2:35-51.
-
(2002)
Curr. Top. Med. Chem.
, vol.2
, pp. 35-51
-
-
Shockcor, J.P.1
Holmes, E.2
-
104
-
-
61349135679
-
Metabolic changes in flatfish hepatic tumours revealed by NMR-based metabolomics and metabolic correlation networks
-
Southam A.D., Easton J.M., Stentiford G.D., Ludwig C., Arvanitis T.N., Viant M.R. Metabolic changes in flatfish hepatic tumours revealed by NMR-based metabolomics and metabolic correlation networks. J. Proteome Res. 2008, 7:5277-5285.
-
(2008)
J. Proteome Res.
, vol.7
, pp. 5277-5285
-
-
Southam, A.D.1
Easton, J.M.2
Stentiford, G.D.3
Ludwig, C.4
Arvanitis, T.N.5
Viant, M.R.6
-
105
-
-
60149091657
-
Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression
-
Sreekumar A., Poisson L.M., Rajendiran T.M., Khan A.P., Cao Q., Yu J., et al. Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression. Nature 2009, 457:910-914.
-
(2009)
Nature
, vol.457
, pp. 910-914
-
-
Sreekumar, A.1
Poisson, L.M.2
Rajendiran, T.M.3
Khan, A.P.4
Cao, Q.5
Yu, J.6
-
106
-
-
67349209541
-
Metabolic profiling of transgenic wheat over-expressing the high-molecular-weight Dx5 glutenin subunit
-
Stamova B.S., Roessner U., Suren S., Laudencia-Chingcuanco D., Bacic A., Beckles D.M. Metabolic profiling of transgenic wheat over-expressing the high-molecular-weight Dx5 glutenin subunit. Metabolomics 2009, 5:239-252.
-
(2009)
Metabolomics
, vol.5
, pp. 239-252
-
-
Stamova, B.S.1
Roessner, U.2
Suren, S.3
Laudencia-Chingcuanco, D.4
Bacic, A.5
Beckles, D.M.6
-
107
-
-
34347384910
-
Normalization method for metabolomics data using optimal selection of multiple internal standards
-
Sysi-Aho M., Katajamaa M., Yetukuri L., Orešič M. Normalization method for metabolomics data using optimal selection of multiple internal standards. BMC Bioinformatics 2007, 8:93.
-
(2007)
BMC Bioinformatics
, vol.8
, pp. 93
-
-
Sysi-Aho, M.1
Katajamaa, M.2
Yetukuri, L.3
Orešič, M.4
-
108
-
-
1642456637
-
Use of relaxation-edited one-dimensional and two-dimensional nuclear magnetic resonance spectroscopy to improve detection of small metabolites in blood plasma
-
Tang H., Wang Y., Nicholson J.K., Lindon J.C. Use of relaxation-edited one-dimensional and two-dimensional nuclear magnetic resonance spectroscopy to improve detection of small metabolites in blood plasma. Anal. Biochem. 2004, 325:260-272.
-
(2004)
Anal. Biochem.
, vol.325
, pp. 260-272
-
-
Tang, H.1
Wang, Y.2
Nicholson, J.K.3
Lindon, J.C.4
-
109
-
-
61849120270
-
A new approach to toxicity testing in Daphnia magna: application of high throughput FT-ICR mass spectrometry metabolomics
-
Taylor N.S., Weber R.J.M., Southam A.D., Payne T.G., Hrydziuszko O., Arvanitis T.N., Viant M.R. A new approach to toxicity testing in Daphnia magna: application of high throughput FT-ICR mass spectrometry metabolomics. Metabolomics 2009, 5:44-58.
-
(2009)
Metabolomics
, vol.5
, pp. 44-58
-
-
Taylor, N.S.1
Weber, R.J.M.2
Southam, A.D.3
Payne, T.G.4
Hrydziuszko, O.5
Arvanitis, T.N.6
Viant, M.R.7
-
110
-
-
30044452058
-
Aryl hydrocarbon receptor regulates distinct dioxin-dependent and dioxin-independent gene batteries
-
Tijet N., Boutros P.C., Moffat I.D., Okey A.B., Tuomisto J., Pohjanvirta R. Aryl hydrocarbon receptor regulates distinct dioxin-dependent and dioxin-independent gene batteries. Mol. Pharmacol. 2006, 69:140-153.
-
(2006)
Mol. Pharmacol.
, vol.69
, pp. 140-153
-
-
Tijet, N.1
Boutros, P.C.2
Moffat, I.D.3
Okey, A.B.4
Tuomisto, J.5
Pohjanvirta, R.6
-
111
-
-
70149116999
-
-
Temporally resolved GC-MS-based metabolic profiling of herbicide treated plants reveals that changes in polar primary metabolites alone can distinguish herbicides of differing mode of action. Metabolomics DOI: 10.1007/s11306-008-0149-8.
-
Trenkamp, S., Eckes, P., Busch, M., and Fernie, A. R. (2009). Temporally resolved GC-MS-based metabolic profiling of herbicide treated plants reveals that changes in polar primary metabolites alone can distinguish herbicides of differing mode of action. Metabolomics DOI: 10.1007/s11306-008-0149-8.
-
(2009)
-
-
Trenkamp, S.1
Eckes, P.2
Busch, M.3
Fernie, A.R.4
-
112
-
-
61849116270
-
1H NMR metabolomic study of the exposure of the marine mussel Mytilus edulis to atrazine, lindane, hypoxia and starvation
-
1H NMR metabolomic study of the exposure of the marine mussel Mytilus edulis to atrazine, lindane, hypoxia and starvation. Metabolomics 2009, 5:33-43.
-
(2009)
Metabolomics
, vol.5
, pp. 33-43
-
-
Tuffnail, W.1
Mills, G.A.2
Cary, P.3
Greenwood, R.4
-
113
-
-
0037459105
-
The depletion of protein signals in metabonomics analysis with the WET-CPMG pulse sequence
-
Van Q.N., Chmurny G.N., Veenstra T.D. The depletion of protein signals in metabonomics analysis with the WET-CPMG pulse sequence. Biochem. Biophys. Res. Commun. 2003, 301:952-959.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.301
, pp. 952-959
-
-
Van, Q.N.1
Chmurny, G.N.2
Veenstra, T.D.3
-
114
-
-
63249088844
-
Co-inhibition of Plasmodium falciparum S-adenosylmethionine decarboxylase/ornithine decarboxylase reveals perturbation-specific compensatory mechanisms by transcriptome, proteome, and metabolome analyses
-
van Brummelen A.C., Olszewski K.L., Wilinski D., Llinas M., Louw A.I., Birkholtz L.-M. Co-inhibition of Plasmodium falciparum S-adenosylmethionine decarboxylase/ornithine decarboxylase reveals perturbation-specific compensatory mechanisms by transcriptome, proteome, and metabolome analyses. J. Biol. Chem. 2009, 284:4635-4646.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 4635-4646
-
-
van Brummelen, A.C.1
Olszewski, K.L.2
Wilinski, D.3
Llinas, M.4
Louw, A.I.5
Birkholtz, L.-M.6
-
115
-
-
0141757204
-
Improved methods for the acquisition and interpretation of NMR metabolomic data
-
Viant M.R. Improved methods for the acquisition and interpretation of NMR metabolomic data. Biochem. Biophys. Res. Commun. 2003, 310:943-948.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.310
, pp. 943-948
-
-
Viant, M.R.1
-
116
-
-
34047109055
-
Metabolomics of aquatic organisms: The new "omics" on the block
-
Viant M.R. Metabolomics of aquatic organisms: The new "omics" on the block. Marine Ecol. Progr. Ser. 2007, 332:301-306.
-
(2007)
Marine Ecol. Progr. Ser.
, vol.332
, pp. 301-306
-
-
Viant, M.R.1
-
117
-
-
52649126218
-
Recent developments in environmental metabolomics
-
Viant M.R. Recent developments in environmental metabolomics. Mol. Biosyst. 2008, 4:980-986.
-
(2008)
Mol. Biosyst.
, vol.4
, pp. 980-986
-
-
Viant, M.R.1
-
118
-
-
60449084070
-
Applications of metabolomics to the environmental sciences
-
Viant M.R. Applications of metabolomics to the environmental sciences. Metabolomics 2009, 5:1-2.
-
(2009)
Metabolomics
, vol.5
, pp. 1-2
-
-
Viant, M.R.1
-
119
-
-
0242628319
-
NMR-based metabolomics: A powerful approach for characterizing the effects of environmental stressors on organism health
-
Viant M.R., Rosenblum E.S., Tieerdema R.S. NMR-based metabolomics: A powerful approach for characterizing the effects of environmental stressors on organism health. Environ. Sci. Technol. 2003, 37:4982-4989.
-
(2003)
Environ. Sci. Technol.
, vol.37
, pp. 4982-4989
-
-
Viant, M.R.1
Rosenblum, E.S.2
Tieerdema, R.S.3
-
122
-
-
19644385170
-
Mass spectrometry in metabolome analysis
-
Villas-Boas S.G., Mas S., Akesson M., Smedsgaard J., Nielsen J. Mass spectrometry in metabolome analysis. Mass Spectrom. Rev. 2005, 24:613-646.
-
(2005)
Mass Spectrom. Rev.
, vol.24
, pp. 613-646
-
-
Villas-Boas, S.G.1
Mas, S.2
Akesson, M.3
Smedsgaard, J.4
Nielsen, J.5
-
123
-
-
0242690435
-
1H nuclear magnetic resonance spectroscopy of liver tissues
-
1H nuclear magnetic resonance spectroscopy of liver tissues. Anal. Biochem. 2003, 323:26-32.
-
(2003)
Anal. Biochem.
, vol.323
, pp. 26-32
-
-
Wang, Y.1
Bollard, M.E.2
Keun, H.3
Antti, H.4
Beckonert, O.5
Ebbels, T.M.6
Lindon, J.C.7
Holmes, E.8
Tang, H.9
Nicholson, J.K.10
-
124
-
-
0142040405
-
Metabolomics in system biology
-
Weckwerth W. Metabolomics in system biology. Annu. Rev. Plant Biol. 2003, 54:669-689.
-
(2003)
Annu. Rev. Plant Biol.
, vol.54
, pp. 669-689
-
-
Weckwerth, W.1
-
125
-
-
0942265392
-
Process for the integrated extraction, identification and quantification of metabolites, proteins and RNA to reveal their co-regulation in biochemical networks.
-
Weckwerth W., Wenzel K., Fiehn O. Process for the integrated extraction, identification and quantification of metabolites, proteins and RNA to reveal their co-regulation in biochemical networks. Proteomics 2004, 4:78-83.
-
(2004)
Proteomics
, vol.4
, pp. 78-83
-
-
Weckwerth, W.1
Wenzel, K.2
Fiehn, O.3
-
126
-
-
34248141676
-
Fluxomics: mass spectrometry versus quantitative imaging
-
Wiechert W., Schweissgut O., Takanaga H., Frommer W.B. Fluxomics: mass spectrometry versus quantitative imaging. Curr. Opin. Plant Biol. 2007, 10:323-330.
-
(2007)
Curr. Opin. Plant Biol.
, vol.10
, pp. 323-330
-
-
Wiechert, W.1
Schweissgut, O.2
Takanaga, H.3
Frommer, W.B.4
-
127
-
-
12944320855
-
HPLC-MS-based methods for the study of metabonomics
-
Wilson I.D., Plumb R., Granger J., Major H., Williams R., Lenz E.M. HPLC-MS-based methods for the study of metabonomics. J. Chromatogr. B 2005, 817:67-76.
-
(2005)
J. Chromatogr. B
, vol.817
, pp. 67-76
-
-
Wilson, I.D.1
Plumb, R.2
Granger, J.3
Major, H.4
Williams, R.5
Lenz, E.M.6
-
128
-
-
17444404226
-
High resolution "ultra performance" liquid chromatography coupled to oa-TOF mass spectrometry as a tool for differential metabolic pathway profiling in functional genomic studies
-
Wilson I.D., Nicholson J.K., Castro-Perez J., Granger J.H., Johnson K.A., Smith B.W., Plumb R.S. High resolution "ultra performance" liquid chromatography coupled to oa-TOF mass spectrometry as a tool for differential metabolic pathway profiling in functional genomic studies. J. Proteome Res. 2005, 4:591-598.
-
(2005)
J. Proteome Res.
, vol.4
, pp. 591-598
-
-
Wilson, I.D.1
Nicholson, J.K.2
Castro-Perez, J.3
Granger, J.H.4
Johnson, K.A.5
Smith, B.W.6
Plumb, R.S.7
-
129
-
-
41049096359
-
Quantitative metabolomics using NMR
-
Wishart D.S. Quantitative metabolomics using NMR. Trends Anal. Chem. 2008, 27:228-237.
-
(2008)
Trends Anal. Chem.
, vol.27
, pp. 228-237
-
-
Wishart, D.S.1
-
130
-
-
33846227380
-
Automated screening for metabolites in complex mixtures using 2D COSY NMR spectroscopy
-
Xi Y., deRopp J.S., Viant M.R., Woodruff D.L., Yu P. Automated screening for metabolites in complex mixtures using 2D COSY NMR spectroscopy. Metabolomics 2007, 2:221-233.
-
(2007)
Metabolomics
, vol.2
, pp. 221-233
-
-
Xi, Y.1
deRopp, J.S.2
Viant, M.R.3
Woodruff, D.L.4
Yu, P.5
-
132
-
-
38349045405
-
Integrated NMR-based metabonomic investigation of early metabolic effects of ethylene glycol monomethyl ether (EGME) on male reproductive organs in rats
-
Yamamoto T., Horii I., Yoshida T. Integrated NMR-based metabonomic investigation of early metabolic effects of ethylene glycol monomethyl ether (EGME) on male reproductive organs in rats. J. Toxicol. Sci. 2007, 32:515-528.
-
(2007)
J. Toxicol. Sci.
, vol.32
, pp. 515-528
-
-
Yamamoto, T.1
Horii, I.2
Yoshida, T.3
-
133
-
-
63649128102
-
Development of a robust and repeatable UPLC-MS method for the long-term metabolomic study of human serum
-
Zelena E., Dunn W.B., Broadhurst D., Francis-McIntyre S., Carroll K.M., Begley P., O'Hagan S., Knowles J.D., Halsall A., Wilson I.D., Kell D.B. Development of a robust and repeatable UPLC-MS method for the long-term metabolomic study of human serum. Anal. Chem. 2009, 81:1357-1364.
-
(2009)
Anal. Chem.
, vol.81
, pp. 1357-1364
-
-
Zelena, E.1
Dunn, W.B.2
Broadhurst, D.3
Francis-McIntyre, S.4
Carroll, K.M.5
Begley, P.6
O'Hagan, S.7
Knowles, J.D.8
Halsall, A.9
Wilson, I.D.10
Kell, D.B.11
-
134
-
-
0037879092
-
A reference map of a human pituitary adenoma proteome
-
Zhan X., Desiderio D.M. A reference map of a human pituitary adenoma proteome. Proteomics 2003, 3(5):699-713.
-
(2003)
Proteomics
, vol.3
, Issue.5
, pp. 699-713
-
-
Zhan, X.1
Desiderio, D.M.2
-
135
-
-
61649091386
-
Metabolic profiling of transgenic rice with cryIAc and sck genes: an evaluation of unintended effects at metabolic level by using GC-FID and GC-MS
-
Zhou J., Ma C., Xu H., Yuan K., Lu X., Zhu Z., Wu Y., Xu G. Metabolic profiling of transgenic rice with cryIAc and sck genes: an evaluation of unintended effects at metabolic level by using GC-FID and GC-MS. J. Chromatogr. B 2009, 877:725-732.
-
(2009)
J. Chromatogr. B
, vol.877
, pp. 725-732
-
-
Zhou, J.1
Ma, C.2
Xu, H.3
Yuan, K.4
Lu, X.5
Zhu, Z.6
Wu, Y.7
Xu, G.8
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