Challenges and developments in tandem mass spectrometry based clinical metabolomics

Molecular and Cellular Endocrinology

Volumn 301, Issue 1-2, 2009, Pages 266-271

  Ceglarek, Uta ^a   Leichtle, Alexander ^a   Brügel, Mathias ^a   Kortz, Linda ^a   Brauer, Romy ^a   Bresler, Kristin ^a   Thiery, Joachim ^a   Fiedler, Georg Martin ^a  

^a UNIVERSITY HOSPITAL LEIPZIG   (Germany)

Author keywords

Clinical metabolomics; Linear ion trap; Metabolite profiling; Tandem mass spectrometry; Targeted metabolomics

Indexed keywords

ARTICLE; ELECTROSPRAY; GAS CHROMATOGRAPHY; ION TRAP MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLOME; METABOLOMICS; METHODOLOGY; PRIORITY JOURNAL; TANDEM MASS SPECTROMETRY; TIME OF FLIGHT MASS SPECTROMETRY;

AMINO ACIDS; BIOMETRY; CARNITINE; EICOSANOIDS; ESTRADIOL; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; INFANT, NEWBORN; MACROPHAGES; METABOLOME; METABOLOMICS; NEONATAL SCREENING; TANDEM MASS SPECTROMETRY; TESTOSTERONE;

EID: 60249102576     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mce.2008.10.013     Document Type: Article

References (31)

1. Arn P.H. Newborn screening: current status. Health Aff. (Millwood) 26 2 (2007) 559-566
2. Baumann S., Ceglarek U., et al. Standardized approach to proteome profiling of human serum based on magnetic bead separation and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Clin. Chem. 51 6 (2005) 973-980
3. Ceglarek U., Muller P., et al. Validation of the phenylalanine/tyrosine ratio determined by tandem mass spectrometry: sensitive newborn screening for phenylketonuria. Clin. Chem. Lab. Med. 40 7 (2002) 693-697
4. Chace D.H., and Kalas T.A. A biochemical perspective on the use of tandem mass spectrometry for newborn screening and clinical testing. Clin. Biochem. 38 4 (2005) 296-309 (PMID 15766731)
5. Deems R.A., Buczynski M.W., et al. Detection and quantitation of eicosanoids via high performance liquid chromatography/electrospray ionization mass spectrometry. Meth. Enzymol. vol. 432 (2007), Academic Press
6. Dettmer K., Aronov P.A., et al. Mass spectrometry-based metabolomics. Mass Spectrom. Rev. 26 1 (2007) 51-78
7. Dunn W.B. Current trends and future requirements for the mass spectrometric investigation of microbial, mammalian and plant metabolomes. Phys. Biol. 5 1 (2008) 11001
8. Dunn W.B., Bailey N.J., et al. Measuring the metabolome: current analytical technologies. Analyst 130 5 (2005) 606-625
9. Fiedler G.M., Baumann S., et al. Standardized peptidome profiling of human urine by magnetic bead separation and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Clin. Chem. 53 3 (2007) 421-428
10. Fingerhut R. Recall rate and positive predictive value of MSUD screening is not influenced by hydroxyproline. Eur. J. Pediatr. (2008)
11. Goodacre R., Vaidyanathan S., et al. Metabolomics by numbers: acquiring and understanding global metabolite data. Trends Biotechnol. 22 5 (2004) 245-252
12. Hall R.D. Plant metabolomics: from holistic hope, to hype, to hot topic. New Phytol. 169 3 (2006) 453-468
13. Hoffmann G., Aramaki S., et al. Quantitative analysis for organic acids in biological samples: batch isolation followed by gas chromatographic-mass spectrometric analysis. Clin. Chem. 35 4 (1989) 587-595
14. Jellum E. Profiling of human body fluids in healthy and diseased states using gas chromatography and mass spectrometry, with special reference to organic acids. J. Chromatogr. 143 5 (1977) 427-462
15. Kayton A. Newborn screening: a literature review. Neonatal Netw. 26 2 (2007) 85-95
16. King R., and Fernandez-Metzler C. The use of Qtrap technology in drug metabolism. Curr. Drug Metab. 7 5 (2006) 541-545
17. Marquet P. Progress of liquid chromatography-mass spectrometry in clinical and forensic toxicology. Ther. Drug Monit. 24 2 (2002) 255-276
18. Martin D.B., Holzman T., et al. MRMer: an interactive open-source and cross-platform system for data extraction and visualization of multiple reaction monitoring experiments. Mol. Cell Proteomics (2008)
19. Mashego M.R., Rumbold K., et al. Microbial metabolomics: past, present and future methodologies. Biotechnol. Lett. 29 1 (2007) 1-16
20. McCabe L.L., and McCabe E.R. Expanded newborn screening: implications for genomic medicine. Annu. Rev. Med. 59 (2008) 163-175
21. Pasikanti K.K., Ho P.C., et al. Development and validation of a gas chromatography/mass spectrometry metabonomic platform for the global profiling of urinary metabolites. Rapid Commun. Mass Spectrom. 22 19 (2008) 2984-2992
22. Pattin K.A., and Moore J.H. Exploiting the proteome to improve the genome-wide genetic analysis of epistasis in common human diseases. Hum. Genet. 124 1 (2008) 19-29
23. Rashed M.S., Ozand P.T., et al. Diagnosis of inborn errors of metabolism from blood spots by acylcarnitines and amino acids profiling using automated electrospray tandem mass spectrometry. Pediatr. Res. 38 3 (1995) 324-331
24. Schulze A., Lindner M., et al. Expanded newborn screening for inborn errors of metabolism by electrospray ionization-tandem mass spectrometry: results, outcome, and implications. Pediatrics 111 6 (2003) 1399-1406
25. Steinfath M., Repsilber D., et al. Integrated data analysis for genome-wide research. Exs 97 (2007) 309-329
26. Tarini B.A. The current revolution in newborn screening: new technology, old controversies. Arch. Pediatr. Adolesc. Med. 161 8 (2007) 767-772
27. Weigel J.F., Janzen N., et al. Tandem mass spectrometric determination of succinylacetone in dried blood spots enables presymptomatic detection in a case of hepatorenal tyrosinaemia. J. Inherit. Metab. Dis. 30 4 (2007) 610
28. Wilcken B. Recent advances in newborn screening. J. Inherit. Metab. Dis. 30 2 (2007) 129-133
29. Wilcken B., and Wiley V. Newborn screening. Pathology 40 2 (2008) 104-115
30. 1H NMR and HPLC-TOF MS. Mol. Biosyst. 1 2 (2005) 166-175
31. Wilson I.D., Plumb R., et al. HPLC-MS-based methods for the study of metabonomics. J. Chromatogr. B: Analyt. Technol. Biomed. Life Sci. 817 1 (2005) 67-76