Novel oligonucleotides containing two 3′-ends complementary to target mRNA show optimal gene-silencing activity

Journal of Medicinal Chemistry

Volumn 54, Issue 8, 2011, Pages 3027-3036

  Bhagat, Lakshmi ^a   Putta, Mallikarjuna Reddy ^a   Wang, Daqing ^a   Yu, Dong ^a   Lan, Tao ^a   Jiang, Weiwen ^a   Sun, Zhenhua ^a   Wang, Hao ^a   Tang, Jimmy X ^a   La Monica, Nicola ^a   Kandimalla, Ekambar R ^a   Agrawal, Sudhir ^a  

^a HYBRIDON INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; MYELOID DIFFERENTIATION FACTOR 88; OLIGODEOXYRIBONUCLEOTIDE; OLIGONUCLEOTIDE PHOSPHOROTHIOATE; OLIGORIBONUCLEOTIDE; TOLL LIKE RECEPTOR 9; VASCULOTROPIN;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; GENE SILENCING; HUMAN; HUMAN CELL;

ANIMALS; BASE SEQUENCE; CELL LINE; DNA PRIMERS; GENE SILENCING; HUMANS; MICE; MYELOID DIFFERENTIATION FACTOR 88; OLIGONUCLEOTIDES; RNA, MESSENGER;

EID: 79955394091     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm200113t     Document Type: Article

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