-
1
-
-
0026551144
-
Antisense oligonucleotides as antiviral agents
-
AGRAWAL, S.: Antisense oligonucleotides as antiviral agents. Trends Biotechnol. 10: 152-158, 1992.
-
(1992)
Trends Biotechnol.
, vol.10
, pp. 152-158
-
-
Agrawal, S.1
-
2
-
-
45949121173
-
Oligodeoxynucleotide methylphosphonate: Synthesis and enzyme degradation
-
AGRAWAL, S. AND GOODCHILD, J.: Oligodeoxynucleotide methylphosphonate: Synthesis and enzyme degradation. Tetrahedron Lett. 28: 3539-3542, 1987.
-
(1987)
Tetrahedron Lett.
, vol.28
, pp. 3539-3542
-
-
Agrawal, S.1
Goodchild, J.2
-
3
-
-
0023755696
-
Oligodeoxynucleoside phosphoramidates and phosphorothioates as inhibitors of human immunodeficiency virus
-
AGRAWAL, S., GOODCHILD, J., CIVIERA, M. P., THORTON, A. H., SARIN, P. S. AND ZAMECNIK, P. C.: Oligodeoxynucleoside phosphoramidates and phosphorothioates as inhibitors of human immunodeficiency virus. Proc. Natl. Acad. Sci. U.S.A. 85: 7079-7083, 1988.
-
(1988)
Proc. Natl. Acad. Sci. U.S.A.
, vol.85
, pp. 7079-7083
-
-
Agrawal, S.1
Goodchild, J.2
Civiera, M.P.3
Thorton, A.H.4
Sarin, P.S.5
Zamecnik, P.C.6
-
4
-
-
0028921636
-
Modified oligonucleotides as therapeutic and diagnostic agents
-
AGRAWAL, S. AND IYER, R. P.: Modified oligonucleotides as therapeutic and diagnostic agents. Curr. Opin. Biotechnol. 6: 112-119, 1995.
-
(1995)
Curr. Opin. Biotechnol.
, vol.6
, pp. 112-119
-
-
Agrawal, S.1
Iyer, R.P.2
-
5
-
-
0025015229
-
Site specific excision from RNA by RNase H and mixed phosphate backbone oligodeoxynucleotides
-
AGRAWAL, S., MAYRAND, S., ZAMECNIK, P. C. AND PEDERSON, T.: Site specific excision from RNA by RNase H and mixed phosphate backbone oligodeoxynucleotides. Proc. Natl. Acad. Sci. U.S.A. 87: 1401-1405, 1990.
-
(1990)
Proc. Natl. Acad. Sci. U.S.A.
, vol.87
, pp. 1401-1405
-
-
Agrawal, S.1
Mayrand, S.2
Zamecnik, P.C.3
Pederson, T.4
-
6
-
-
0027023642
-
GEM 91: An antisense oligonucleotide phosphorothioate as a therapeutic agent for AIDS
-
AGRAWAL, S. AND TANG, J. Y.: GEM 91: An antisense oligonucleotide phosphorothioate as a therapeutic agent for AIDS. Antisense Res. Dev. 2: 261-266, 1992.
-
(1992)
Antisense Res. Dev.
, vol.2
, pp. 261-266
-
-
Agrawal, S.1
Tang, J.Y.2
-
7
-
-
0027220416
-
Self-stabilized antisense oligodeoxynucleotide phosphorothioates: Properties and anti-HIV activity
-
AGRAWAL, S. AND TANG, J. Y.: Self-stabilized antisense oligodeoxynucleotide phosphorothioates: Properties and anti-HIV activity. Nucleic Acids Res. 21: 27-35, 1993.
-
(1993)
Nucleic Acids Res.
, vol.21
, pp. 27-35
-
-
Agrawal, S.1
Tang, J.Y.2
-
8
-
-
0025743216
-
Pharmacokinetics, biodistribution and stability of oligodeoxynucleotide phosphorothioates in mice
-
AGRAWAL, S., TEMSAMANI, J. AND TANG, J. Y.: Pharmacokinetics, biodistribution and stability of oligodeoxynucleotide phosphorothioates in mice. Proc. Natl. Acad. Sci. U.S.A. 88: 7595-7599, 1991.
-
(1991)
Proc. Natl. Acad. Sci. U.S.A.
, vol.88
, pp. 7595-7599
-
-
Agrawal, S.1
Temsamani, J.2
Tang, J.Y.3
-
9
-
-
0028850751
-
Pharmacokinetics of antisense oligonucleotides
-
AGRAWAL, S., TEMSAMANI, J., GALBRAITH, W. AND TANG, J. Y.: Pharmacokinetics of antisense oligonucleotides. Clin. Pharm. 28: 7-16, 1995a.
-
(1995)
Clin. Pharm.
, vol.28
, pp. 7-16
-
-
Agrawal, S.1
Temsamani, J.2
Galbraith, W.3
Tang, J.Y.4
-
10
-
-
85053356721
-
Self-stabilized oligonucleotides as novel antisense agents
-
ed. by S. Akhtar, CRC Press, New York
-
AGRAWAL, S., TEMSAMANI, J. AND TANG, J. Y.: Self-stabilized oligonucleotides as novel antisense agents. In Delivery Strategies: Antisense Oligonucleotide Therapeutics, ed. by S. Akhtar, pp. 105-121, CRC Press, New York, 1995b.
-
(1995)
Delivery Strategies: Antisense Oligonucleotide Therapeutics
, pp. 105-121
-
-
Agrawal, S.1
Temsamani, J.2
Tang, J.Y.3
-
11
-
-
0029100397
-
Absorption, tissue distribution and in vivo stability in rats of a hybrid antisenae oligonucleotide following oral administration
-
AGRAWAL, S., ZHANG, X., ZHAO, H., LU, Z., YAN, J., CAI, H., DIASIO, R. B., HABUS, I., JIANG, Z., IYER, R. P., YU, D. AND ZHANG, R.: Absorption, tissue distribution and in vivo stability in rats of a hybrid antisenae oligonucleotide following oral administration. Biochem. Pharmacol. 50: 571-576, 1995c.
-
(1995)
Biochem. Pharmacol.
, vol.50
, pp. 571-576
-
-
Agrawal, S.1
Zhang, X.2
Zhao, H.3
Lu, Z.4
Yan, J.5
Cai, H.6
Diasio, R.B.7
Habus, I.8
Jiang, Z.9
Iyer, R.P.10
Yu, D.11
Zhang, R.12
-
12
-
-
0029588561
-
Novel enzymatic and immunological responses to oligonucleotides
-
AGRAWAL, S., RUSTOGI, P. K. AND SHAW, D. R.: Novel enzymatic and immunological responses to oligonucleotides. Toxicol. Lett. 83: 431-434, 1995d.
-
(1995)
Toxicol. Lett.
, vol.83
, pp. 431-434
-
-
Agrawal, S.1
Rustogi, P.K.2
Shaw, D.R.3
-
13
-
-
0027729703
-
Systemic administration of a phosphorothioate oligonucleotide with a sequence complementary to p53 for acute myelogenous leukemia and myelodysplastic syndrome: Initial results of a phase 1 trial
-
BAYEVER, E., IVERSON, P. L., BISHOP, M. R., SHARP, J. G., TEWARY, H. K., ARNESON, M. A., PIRRUCCELLO, S. J., RUDDON, R. W., KESSINGER, A., ZON, G. AND ARMITAGE, O.: Systemic administration of a phosphorothioate oligonucleotide with a sequence complementary to p53 for acute myelogenous leukemia and myelodysplastic syndrome: Initial results of a phase 1 trial. Antisense Res. Dev. 3: 383-390, 1993.
-
(1993)
Antisense Res. Dev.
, vol.3
, pp. 383-390
-
-
Bayever, E.1
Iverson, P.L.2
Bishop, M.R.3
Sharp, J.G.4
Tewary, H.K.5
Arneson, M.A.6
Pirruccello, S.J.7
Ruddon, R.W.8
Kessinger, A.9
Zon, G.10
Armitage, O.11
-
14
-
-
0025175236
-
Disposition and metabolism of oligodeoxynucleoside methylphosphonate following a single IV injection in mice
-
CHEN, T. L., MILLER, P. S., Ts'O, P. O. P. AND COLVIN, O. M.: Disposition and metabolism of oligodeoxynucleoside methylphosphonate following a single IV injection in mice. Drug Metab. Dispos. 18: 815-518, 1990.
-
(1990)
Drug Metab. Dispos.
, vol.18
, pp. 815-1518
-
-
Chen, T.L.1
Miller, P.S.2
Ts'o, P.O.P.3
Colvin, O.M.4
-
15
-
-
0027786912
-
14C-labeled phosphorothioate oligonucleotide ISIS 2105, after intravenous administration to rats
-
14C-labeled phosphorothioate oligonucleotide ISIS 2105, after intravenous administration to rats. J. Pharmacol. Exp. Ther. 267: 1181-1190, 1993.
-
(1993)
J. Pharmacol. Exp. Ther.
, vol.267
, pp. 1181-1190
-
-
Cossum, P.A.1
Sasmor, H.2
Delinger, S.3
Truong, L.4
Cummins, L.5
Owens, S.R.6
Markham, P.M.7
Shea, J.P.8
Crooke, S.9
-
17
-
-
0028568244
-
14C-labeled afovirsen sodium in patients with genital warts
-
14C-labeled afovirsen sodium in patients with genital warts. Clin. Pharmacol. Ther. 56: 641-646, 1994.
-
(1994)
Clin. Pharmacol. Ther.
, vol.56
, pp. 641-646
-
-
Crooke, S.T.1
Grillone, L.R.2
Tendolkar, A.3
Garrett, A.4
Fratkin, N.J.5
Leeds, J.6
Barr, W.H.7
-
18
-
-
0001900381
-
A dinucleoside phosphorothioate
-
ECKSTEIN, F.: A dinucleoside phosphorothioate. Tetrahedron Lett. 8: 1157-1160, 1967.
-
(1967)
Tetrahedron Lett.
, vol.8
, pp. 1157-1160
-
-
Eckstein, F.1
-
19
-
-
0028596461
-
Complement activation and hemodynamic changes following intravenous administration of phosphorothioate oligonucleotides in the monkey
-
GALBRAITH, W. M., HOBSON, W. C., GICLAS, P. C., SCHECHTER, P. I. AND AGRAWAL, S.: Complement activation and hemodynamic changes following intravenous administration of phosphorothioate oligonucleotides in the monkey. Antisense Res. Dev. 4: 201-206, 1994.
-
(1994)
Antisense Res. Dev.
, vol.4
, pp. 201-206
-
-
Galbraith, W.M.1
Hobson, W.C.2
Giclas, P.C.3
Schechter, P.I.4
Agrawal, S.5
-
20
-
-
0000064988
-
In vivo studies with phosphorothioate oligonucleotides: Rationale for systemic therapy
-
ed. by S. T. Crooke and B. Lebleu, CRC Press, Boca Raton, FL
-
IVERSON, P. L.: In vivo studies with phosphorothioate oligonucleotides: Rationale for systemic therapy. In Antisense Research and Applications, ed. by S. T. Crooke and B. Lebleu, pp. 461-469, CRC Press, Boca Raton, FL, 1993.
-
(1993)
Antisense Research and Applications
, pp. 461-469
-
-
Iverson, P.L.1
-
21
-
-
0028136417
-
Pharmacokinetics of an antisense phosphorothioate oligodeoxynucleotide against rev from human immunodeficiency virus type 1 in the adult male rat following single injections and continuous infusion
-
IVERSON, P., MATA, J., THACEWELL, W. G. AND ZON, G.: Pharmacokinetics of an antisense phosphorothioate oligodeoxynucleotide against rev from human immunodeficiency virus type 1 in the adult male rat following single injections and continuous infusion. Antisense Res. Dev. 4: 43-52, 1994.
-
(1994)
Antisense Res. Dev.
, vol.4
, pp. 43-52
-
-
Iverson, P.1
Mata, J.2
Thacewell, W.G.3
Zon, G.4
-
22
-
-
0028598284
-
Study of antisense oligonucleotide phosphorothioates containing segments of oligodeoxynucleotides and 2′-O-methyloligoribonucleotides
-
METELEV, V., LISZIEWICZ, J. AND AGRAWAL, S.: Study of antisense oligonucleotide phosphorothioates containing segments of oligodeoxynucleotides and 2′-O-methyloligoribonucleotides. Bioorg. Med. Chem. Lett. 4: 2929-2934, 1994.
-
(1994)
Bioorg. Med. Chem. Lett.
, vol.4
, pp. 2929-2934
-
-
Metelev, V.1
Lisziewicz, J.2
Agrawal, S.3
-
23
-
-
0028574140
-
Large-scale synthesis, purification and analysis of oligodeoxynucleotide phosphorothioates
-
PADMAPRIYA, A. P., TANG, J. Y. AND AGRAWAL, S.: Large-scale synthesis, purification and analysis of oligodeoxynucleotide phosphorothioates. Antisense Res. Dev. 4: 185-199, 1994.
-
(1994)
Antisense Res. Dev.
, vol.4
, pp. 185-199
-
-
Padmapriya, A.P.1
Tang, J.Y.2
Agrawal, S.3
-
25
-
-
0001476029
-
Inhibition of acquired immunodeficiency syndrome virus by oligonucleoside methylphosphonates
-
SARIN, P. S., AGRAWAL, S., CIVIERA, M. P., GOODCHILD, J., IKEUCHI, T. AND ZAMECNIK, P. C.: Inhibition of acquired immunodeficiency syndrome virus by oligonucleoside methylphosphonates. Proc. Natl. Acad. Sci. U.S.A. 85: 7448-7451, 1988.
-
(1988)
Proc. Natl. Acad. Sci. U.S.A.
, vol.85
, pp. 7448-7451
-
-
Sarin, P.S.1
Agrawal, S.2
Civiera, M.P.3
Goodchild, J.4
Ikeuchi, T.5
Zamecnik, P.C.6
-
26
-
-
0027933160
-
In vivo toxicological effects of rel A antisense phoephorothioates in CD-1 mice
-
SARMIENTO, U. M., FEREZ, J. R., BECKER, J. M. AND NARAYANAN, R.: In vivo toxicological effects of rel A antisense phoephorothioates in CD-1 mice. Antisense Res. Dev. 4: 99-107, 1994.
-
(1994)
Antisense Res. Dev.
, vol.4
, pp. 99-107
-
-
Sarmiento, U.M.1
Ferez, J.R.2
Becker, J.M.3
Narayanan, R.4
-
27
-
-
0027756125
-
Pharmacokinetics, biodistribution, and stability of capped oligonucleotide phosphorothioates in mice
-
TEMSAMANI, J., TANG, J. Y., PADMAPRIYA, A., KUBERT, M. AND AGRAWAL, S.: Pharmacokinetics, biodistribution, and stability of capped oligonucleotide phosphorothioates in mice. Antisense Res. Dev. 3: 277-284, 1993.
-
(1993)
Antisense Res. Dev.
, vol.3
, pp. 277-284
-
-
Temsamani, J.1
Tang, J.Y.2
Padmapriya, A.3
Kubert, M.4
Agrawal, S.5
-
28
-
-
0026215190
-
Nonionic oligonucleotide analogues (Matagen) as anticodic agents in duplex and triplex formation
-
Ts'O, P. O. P.: Nonionic oligonucleotide analogues (Matagen) as anticodic agents in duplex and triplex formation. Antisense Res. Dev. 1: 273-283, 1991.
-
(1991)
Antisense Res. Dev.
, vol.1
, pp. 273-283
-
-
Ts'o, P.O.P.1
-
29
-
-
11944267365
-
Antisense oligonucleotide: A new therapeutic principle
-
UHLMANN, E. AND PEYMAN, A.: Antisense oligonucleotide: A new therapeutic principle. Chem. Rev. 90: 544-584, 1990.
-
(1990)
Chem. Rev.
, vol.90
, pp. 544-584
-
-
Uhlmann, E.1
Peyman, A.2
-
30
-
-
0002142465
-
Oligonucleotide base hybridization as a modulator of genetic message readout
-
ed. by E. Wickstrom, Wiley Liss, New York
-
ZAMECNIK, P. C.: Oligonucleotide base hybridization as a modulator of genetic message readout. In Prospects for Antisense Nucleic Therapy of Cancer and AIDS, ed. by E. Wickstrom, pp. 1-6, Wiley Liss, New York, 1991.
-
(1991)
Prospects for Antisense Nucleic Therapy of Cancer and AIDS
, pp. 1-6
-
-
Zamecnik, P.C.1
-
31
-
-
0029127845
-
Pharmacokinetks of an oligodeoxynucleotide phosphorothioate (GEM 91) in HIV-infected subjects
-
ZHANG, R., YAN, J., SHAHINIAN, H., AMIN, G., LU, Z., LIU, T., SAAG, M. S., JIANG, Z., TEMSAMANI, J., MARTIN, R. R., SCHECHTER, P., AGRAWAL, S. AND DIASIO, R. B.: Pharmacokinetks of an oligodeoxynucleotide phosphorothioate (GEM 91) in HIV-infected subjects. Clin. Pharmacol. Ther. 58: 44-53, 1995a.
-
(1995)
Clin. Pharmacol. Ther.
, vol.58
, pp. 44-53
-
-
Zhang, R.1
Yan, J.2
Shahinian, H.3
Amin, G.4
Lu, Z.5
Liu, T.6
Saag, M.S.7
Jiang, Z.8
Temsamani, J.9
Martin, R.R.10
Schechter, P.11
Agrawal, S.12
Diasio, R.B.13
-
32
-
-
0028934855
-
Pharmacokinetks and tissue distribution in rats of an oligodeoxynucleotide phosphorothioate (GEM 91) developed as a therapeutic agent for human immunodeficiency virus type-1
-
ZHANG, R., DIASIO, R. B., LU, Z., LIU, T. P., JIANG, Z., GALBRAITH, W. AND AGRAWAL, S.: Pharmacokinetks and tissue distribution in rats of an oligodeoxynucleotide phosphorothioate (GEM 91) developed as a therapeutic agent for human immunodeficiency virus type-1. Biochem. Pharmacol. 49: 929-939, 1995b.
-
(1995)
Biochem. Pharmacol.
, vol.49
, pp. 929-939
-
-
Zhang, R.1
Diasio, R.B.2
Lu, Z.3
Liu, T.P.4
Jiang, Z.5
Galbraith, W.6
Agrawal, S.7
-
33
-
-
0029002066
-
In vivo stability and disposition of a self-stabilized oligodeoxynucleotide phosphorothioate in rats
-
ZHANG, R., LU, Z., ZHANG, X., ZHAO, H., DIASIO, R. B., LIU, T., JIANG, Z. AND AGRAWAL, S.: In vivo stability and disposition of a self-stabilized oligodeoxynucleotide phosphorothioate in rats. Clin. Chem. 41: 836-843, 1995c.
-
(1995)
Clin. Chem.
, vol.41
, pp. 836-843
-
-
Zhang, R.1
Lu, Z.2
Zhang, X.3
Zhao, H.4
Diasio, R.B.5
Liu, T.6
Jiang, Z.7
Agrawal, S.8
-
34
-
-
0029134526
-
In vivo stability, disposition and metabolism of a 'hybrid' oligonucleotide phosphorothioate in rats
-
ZHANG, R., LU, Z., ZHAO, X., DIASIO, R. B., HABUS, I., IYER, R. P., YU, D. AND AGRAWAL, S.: In vivo stability, disposition and metabolism of a 'hybrid' oligonucleotide phosphorothioate in rats. Biochem. Pharmacol. 50: 545-556, 1995d.
-
(1995)
Biochem. Pharmacol.
, vol.50
, pp. 545-556
-
-
Zhang, R.1
Lu, Z.2
Zhao, X.3
Diasio, R.B.4
Habus, I.5
Iyer, R.P.6
Yu, D.7
Agrawal, S.8
-
35
-
-
0030071007
-
Effect of different modified oligodeoxynucleotides on immune stimulation
-
ZHAO, Q., TEMSAMANI, J., IADAROLA, P. L., JIANG, Z. AND AGRAWAL, S.: Effect of different modified oligodeoxynucleotides on immune stimulation. Biochem. Pharmacol. 51: 173-182, 1996.
-
(1996)
Biochem. Pharmacol.
, vol.51
, pp. 173-182
-
-
Zhao, Q.1
Temsamani, J.2
Iadarola, P.L.3
Jiang, Z.4
Agrawal, S.5
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