메뉴 건너뛰기




Volumn 8, Issue 2, 1998, Pages 135-139

Mixed backbone oligonucleotides: Improvement in oligonucleotide-induced toxicity in vivo

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CYCLIC AMP DEPENDENT PROTEIN KINASE; OLIGODEOXYNUCLEOTIDE PHOSPHOROTHIOATE;

EID: 0031948835     PISSN: 10872906     EISSN: None     Source Type: Journal    
DOI: 10.1089/oli.1.1998.8.135     Document Type: Conference Paper
Times cited : (86)

References (20)
  • 1
    • 0030271959 scopus 로고    scopus 로고
    • Antisense oligonucleotides: Towards clinical trials
    • AGRAWAL, S. (1996). Antisense oligonucleotides: Towards clinical trials Trends Biotechnol. 14, 376-387.
    • (1996) Trends Biotechnol. , vol.14 , pp. 376-387
    • Agrawal, S.1
  • 2
    • 0031457918 scopus 로고    scopus 로고
    • Toxicological effects of an oligodeoxynucleotide phosphorothioate and its analogs following intravenous administration in rats
    • AGRAWAL, S., ZHAO, Q., JIANG, Z., OLIVER, C., GILES, H., HEATH, J., and SEROTA, D. (1997a). Toxicological effects of an oligodeoxynucleotide phosphorothioate and its analogs following intravenous administration in rats. Antisense Nucleic Acid Drug Dev. 7, 575-584.
    • (1997) Antisense Nucleic Acid Drug Dev. , vol.7 , pp. 575-584
    • Agrawal, S.1    Zhao, Q.2    Jiang, Z.3    Oliver, C.4    Giles, H.5    Heath, J.6    Serota, D.7
  • 4
    • 0031027349 scopus 로고    scopus 로고
    • In vivo studies with antisense oligonucleotide
    • AKHTAR, S., and AGRAWAL, S. (1997). In vivo studies with antisense oligonucleotide. Trends Pharm Sci. 18, 12-18.
    • (1997) Trends Pharm Sci. , vol.18 , pp. 12-18
    • Akhtar, S.1    Agrawal, S.2
  • 5
    • 0031912506 scopus 로고    scopus 로고
    • Antisense oligonucleotides: Is the glass half full or half empty?
    • BENNETT, C.F. (1998). Antisense oligonucleotides: Is the glass half full or half empty? Biochem. Pharmacol. 55, 9-19.
    • (1998) Biochem. Pharmacol. , vol.55 , pp. 9-19
    • Bennett, C.F.1
  • 6
    • 0028029170 scopus 로고
    • Cytokines in the generation of immune responses and resolution of virus infection
    • BIRON, C.A. (1994). Cytokines in the generation of immune responses and resolution of virus infection. Crit. Rev. Immunol. 6, 530-538.
    • (1994) Crit. Rev. Immunol. , vol.6 , pp. 530-538
    • Biron, C.A.1
  • 7
    • 0030860337 scopus 로고    scopus 로고
    • Antisense-protein kinase A: A single-gene-based therapeutic approach
    • CHO-CHUNG, Y.S. (1997). Antisense-protein kinase A: A single-gene-based therapeutic approach. Antisense Nucleic Acid Drug Dev. 7, 495-502.
    • (1997) Antisense Nucleic Acid Drug Dev. , vol.7 , pp. 495-502
    • Cho-Chung, Y.S.1
  • 8
    • 0028596461 scopus 로고
    • Complement activation and hemodynamic changes following intravenous administration of phosphorothioate oligonucleotides in the monkey
    • GALBRAITH, W.M., HOBSON, W.C., GICLAS, P.C., SCHECHTER, P.J., and AGRAWAL, S. (1994). Complement activation and hemodynamic changes following intravenous administration of phosphorothioate oligonucleotides in the monkey. Antisense Res. Dev. 4, 201-206.
    • (1994) Antisense Res. Dev. , vol.4 , pp. 201-206
    • Galbraith, W.M.1    Hobson, W.C.2    Giclas, P.C.3    Schechter, P.J.4    Agrawal, S.5
  • 9
    • 0030922755 scopus 로고    scopus 로고
    • Activation of the alternative pathway of complement by a phosphorothioate oligonucleotide: Potential mechanism of action
    • HENRY, S.P., GICLAS, P.C., LEEDS, J., PANGBURN, M., AULETTA, C., LEVIN, A.A., and KORNBRUST, D.J. (1997a). Activation of the alternative pathway of complement by a phosphorothioate oligonucleotide: Potential mechanism of action. J. Pharmacol. Exp. Ther. 281, 810-816.
    • (1997) J. Pharmacol. Exp. Ther. , vol.281 , pp. 810-816
    • Henry, S.P.1    Giclas, P.C.2    Leeds, J.3    Pangburn, M.4    Auletta, C.5    Levin, A.A.6    Kornbrust, D.J.7
  • 13
    • 0024814903 scopus 로고
    • Interleukin 6: A multifunctional cytokine regulating immune reactions and the acute phase protein response
    • LE, J.M., and VILCEK, J. (1989). Interleukin 6: A multifunctional cytokine regulating immune reactions and the acute phase protein response. Lab. Invest. 61, 588-602.
    • (1989) Lab. Invest. , vol.61 , pp. 588-602
    • Le, J.M.1    Vilcek, J.2
  • 14
    • 0029802563 scopus 로고    scopus 로고
    • Role of β-chemokines in suppressing HIV replication
    • LUSSO, P., and GALLO, R.C. (1996). Role of β-chemokines in suppressing HIV replication. Science 274, 1393-1395.
    • (1996) Science , vol.274 , pp. 1393-1395
    • Lusso, P.1    Gallo, R.C.2
  • 15
    • 0029050664 scopus 로고
    • A single-injection protein kinase A-directed antisense treatment to inhibit tumor growth
    • NESTEROVA, M., and CHO-CHUNG, Y.S. (1995). A single-injection protein kinase A-directed antisense treatment to inhibit tumor growth. Nature Med 1, 528-533.
    • (1995) Nature Med , vol.1 , pp. 528-533
    • Nesterova, M.1    Cho-Chung, Y.S.2
  • 16
    • 0030273086 scopus 로고    scopus 로고
    • Immune activation by bacterial DNA: A new genetic code
    • and references therein
    • PISETSKY, D.S. (1996). Immune activation by bacterial DNA: A new genetic code [Review]. Immunity 5, 303-310, and references therein.
    • (1996) Immunity , vol.5 , pp. 303-310
    • Pisetsky, D.S.1
  • 17
    • 0027933160 scopus 로고
    • In vivo toxicological effects of rel A antisense phosphorothioates in CD-1 mice
    • SARMIENTO, U.M., PEREZ, J.R., BECKER, J.M., and NARAYANA, R. (1994). In vivo toxicological effects of rel A antisense phosphorothioates in CD-1 mice. Antisense Res. Dev. 4, 99-107.
    • (1994) Antisense Res. Dev. , vol.4 , pp. 99-107
    • Sarmiento, U.M.1    Perez, J.R.2    Becker, J.M.3    Narayana, R.4
  • 19
    • 0030071007 scopus 로고    scopus 로고
    • Effect of different chemical modified oligodeoxynucleotides on immune stimulation
    • ZHAO, Q., TEMSAMANI, J., IADAROLA, P.L., JIANG, Z.W., and AGRAWAL, S. (1996). Effect of different chemical modified oligodeoxynucleotides on immune stimulation. Biochem. Pharmacol. 51, 173-182.
    • (1996) Biochem. Pharmacol. , vol.51 , pp. 173-182
    • Zhao, Q.1    Temsamani, J.2    Iadarola, P.L.3    Jiang, Z.W.4    Agrawal, S.5
  • 20
    • 0030772278 scopus 로고    scopus 로고
    • Pattern and kinetics of cytokine production following administration of phosphorothioate oligonucleotides in mice
    • ZHAO, Q., TEMSAMANI, J., ZHOU, R.Z., and AGRAWAL, S. (1997). Pattern and kinetics of cytokine production following administration of phosphorothioate oligonucleotides in mice. Antisense Nucleic Acid Drug Dev. 7, 495-502.
    • (1997) Antisense Nucleic Acid Drug Dev. , vol.7 , pp. 495-502
    • Zhao, Q.1    Temsamani, J.2    Zhou, R.Z.3    Agrawal, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.