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Volumn 6, Issue 5, 2011, Pages 876-888

New huprine derivatives functionalized at position9 as highly potent acetylcholinesterase inhibitors

(7) Ronco, Cyril a,b Foucault, Richard c Gillon, Emilie c Bohn, Pierre b Nachon, Florian c Jean, Ludovic a,b Renard, Pierre Yves a,b,d

a Normandie Université (France)

b UNIVERSITÉ DE ROUEN (France)

c INSTITUT DE RECHERCHE BIOMÉDICALE DES ARMÉES (France)

d INSTITUT UNIVERSITAIRE DE FRANCE (France)

Author keywords

Acetylcholinesterase; Alzheimer's disease; Huprine; Inhibitors; Molecular modeling

Indexed keywords

2 (12 AMINO 3 CHLORO 6,7,10,11 TETRAHYDRO 7,11 METHANOCYCLOOCTA[B]QUINOLIN 9 YL)ETHANOL; 2 (12 AMINO 3 CHLORO 6,7,10,11 TETRAHYDRO 7,11 METHANOCYCLOOCTA[B]QUINOLIN 9 YL)ETHYL ACETATE; 2 (12 AMINO 3 CHLORO 6,7,10,11 TETRAHYDRO 7,11 METHANOCYCLOOCTA[B]QUINOLIN 9 YL)ETHYL TRIFLUOROACETATE; CHOLINESTERASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; BLOOD BRAIN BARRIER; CONTROLLED STUDY; DRUG POTENCY; DRUG SCREENING; DRUG SELECTIVITY; DRUG SYNTHESIS; HUMAN; IN VIVO STUDY; LD 50; MOLECULAR DOCKING; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 79955068835 PISSN: 18607179 EISSN: 18607187 Source Type: Journal
DOI: 10.1002/cmdc.201000523 Document Type: Article

Times cited : (36)

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