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Volumn 41, Issue 9, 2002, Pages 2970-2981

3D structure of Torpedo californica acetylcholinesterase complexed with huprine X at 2.1 Å resolution: Kinetic and molecular dynamic correlates

(11) Dvir, H a Wong, D M a Harel, M a Barril, X b Orozco, M b Luque, F J b Munoz Torrero D b Camps, P b Rosenberry, T L c Silman, I a Sussman, Joel L a

a WEIZMANN INSTITUTE OF SCIENCE (Israel)

b UNIVERSITY OF BARCELONA (Spain)

c MAYO CLINIC (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SUBSTRUCTURES;

CHLORINE; DRUG PRODUCTS; ENZYME INHIBITION;

ENZYMES;

ACETYLCHOLINESTERASE; CHOLINESTERASE INHIBITOR; HUPERZINE A; HUPRINE X; HUPRINE Y; TACRINE; UNCLASSIFIED DRUG;

ARTICLE; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DRUG MECHANISM; ENZYME CONFORMATION; ENZYME INHIBITOR INTERACTION; INHIBITION KINETICS; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; TORPEDO CALIFORNICA;

ACETYLCHOLINESTERASE; AMINOQUINOLINES; ANIMALS; BINDING SITES; CHLORINE; CHOLINESTERASE INHIBITORS; COMPUTER SIMULATION; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; HETEROCYCLIC COMPOUNDS WITH 4 OR MORE RINGS; KINETICS; LIGANDS; MODELS, MOLECULAR; PROTEIN CONFORMATION; SESQUITERPENES; SPECIES SPECIFICITY; TACRINE; TORPEDO;

TORPEDO; TORPEDO CALIFORNICA;

EID: 0037022789 PISSN: 00062960 EISSN: None Source Type: Journal
DOI: 10.1021/bi011652i Document Type: Article

Times cited : (132)

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