Programmed death 1 and cytokine inducible SH2-containing protein dependent expansion of regulatory T cells upon stimulation with Mycobacterium tuberculosis

Journal of Infectious Diseases

Volumn 203, Issue 9, 2011, Pages 1256-1263

  Periasamy, Sivakumar ^a,b   Dhiman, Rohan ^a,b   Barnes, Peter F ^a,b,c   Paidipally, Padmaja ^a,b   Tvinnereim, Amy ^a,b   Bandaru, Anuradha ^d   Valluri, Vijaya Lakshmi ^d   Vankayalapati, Ramakrishna ^a,b,e  

^a Ctr Pulmon and Infect Dis Contr   (United States)

^b Department of Microbiology and Immunology ^*  (United States)

^c UNIVERSITY OF TEXAS HEALTH CENTER   (United States)

^d LEPRA Society   (India)

^e UNIVERSITY OF TEXAS AT TYLER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR4; CYTOKINE; CYTOKINE INDUCIBLE SH2 CONTAINING PROTEIN; GAMMA INTERFERON; INTERLEUKIN 10; PROGRAMMED DEATH 1 RECEPTOR; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CD4+ CCR4+ T LYMPHOCYTE; CD4+ CD25+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL EXPANSION; CONTROLLED STUDY; CYTOKINE PRODUCTION; HUMAN; HUMAN CELL; MICROARRAY ANALYSIS; MYCOBACTERIUM TUBERCULOSIS; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; TUBERCULOSIS;

ADOLESCENT; ADULT; AGED; ANTIGENS, CD; ANTIGENS, CD4; APOPTOSIS REGULATORY PROTEINS; HUMANS; MIDDLE AGED; MYCOBACTERIUM TUBERCULOSIS; RECEPTORS, CCR4; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, REGULATORY; TUBERCULOSIS; YOUNG ADULT;

EID: 79954607405     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1093/infdis/jir011     Document Type: Article

References (50)

1. Hori S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 2003;299:1057-61. (Pubitemid 36222930)
2. Chatila TA. Role of regulatory T cells in human diseases. J Allergy Clin Immunol 2005;116:949-59.
3. Sakaguchi S. Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses. Annu Rev Immunol 2004;22:531-62. (Pubitemid 38680433)
4. Rouse BT, Suvas S. Regulatory cells and infectious agents: detentes cordiale and contraire. J Immunol 2004;173:2211-5. (Pubitemid 39063072)
5. Belkaid Y, Piccirillo CA, Mendez S, Shevach EM, Sacks DL. CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity. Nature 2002;420:502-7. (Pubitemid 35477041)
6. Ordway D, Henao-Tamayo M, Harton M, et al. The hypervirulent Mycobacterium tuberculosis strain HN878 induces a potent TH1 response followed by rapid down-regulation. J Immunol 2007;179:522-31. (Pubitemid 46986569)
7. Scott-Browne JP, Shafiani S, Tucker-Heard G, et al. Expansion and function of Foxp3-expressing T regulatory cells during tuberculosis. J Exp Med 2007;204:2159-69. (Pubitemid 47360876)
8. Kursar M, Koch M, Mittrucker HW, et al. Cutting edge: regulatory T cells prevent efficient clearance of Mycobacterium tuberculosis. J Immunol 2007;178:2661-5. (Pubitemid 46333142)
9. Hirsch CS, Toossi Z, Othieno C, et al. Depressed T-cell interferon-gamma responses in pulmonary tuberculosis: analysis of underlying mechanisms and modulation with therapy. J Infect Dis 1999;180:2069-73.
10. Li L, Lao SH, Wu CY. Increased frequency of CD4 (+) CD25 (high) Treg cells inhibit BCG-specific induction of IFN-gamma by CD4 (+) T cells from TB patients. Tuberculosis (Edinb) 2007;87:526-34. (Pubitemid 47595478)
11. Garg A, Barnes PF, Roy S, et al. Mannose-capped lipoarabinomannanand prostaglandin E2-dependent expansion of regulatory T cells in human Mycobacterium tuberculosis infection. Eur J Immunol 2008;38:459-69.
12. Mahan CS, Thomas JJ, Boom WH, Rojas RE. CD4 (+) CD25 (high) Foxp3 (3+) regulatory T cells downregulate human Vdelta2 (+) T-lymphocyte function triggered by anti-CD3 or phosphoantigen. Immunology 2009;127:398-407.
13. Liu W, Putnam AL, Xu-Yu Z, et al. CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ Treg cells. J Exp Med 2006;203:1701-11. (Pubitemid 44036276)
14. Banham AH. Cell-surface IL-7 receptor expression facilitates the purification of FOXP3 (+) regulatory T cells. Trends Immunol 2006;27:541-4. (Pubitemid 44780852)
15. Bayry J, Tchilian EZ, Davies MN, et al. In silico identified CCR4 antagonists target regulatory T cells and exert adjuvant activity in vaccination. Proc Natl Acad Sci U S A 2008;105:10221-6.
16. Zhao Z, Yu S, Fitzgerald DC, et al. IL-12R beta 2 promotes the development of CD4+CD25+ regulatory T cells. J Immunol 2008;181:3870-6.
17. Strauss L, Bergmann C, Szczepanski MJ, Lang S, Kirkwood JM, Whiteside TL. Expression of ICOS on human melanoma-infiltrating CD4+CD25highFoxp3+ T regulatory cells: implications and impact on tumor-mediated immune suppression. J Immunol 2008;180:2967-80.
18. Tang AL, Teijaro JR, Njau MN, et al. CTLA4 expression is an indicator and regulator of steady-state CD4+ FoxP3+ T cell homeostasis. J Immunol 2008;181:1806-13.
19. Li S, Chen S, Xu X, et al. Cytokine-induced Src homology 2 protein (CIS) promotes T cell receptor-mediated proliferation and prolongs survival of activated T cells. J Exp Med 2000;191:985-94.
20. Tenbrock K, Juang YT, Tolnay M, Tsokos GC. The cyclic adenosine 5'-monophosphate response element modulator suppresses IL-2 production in stimulated T cells by a chromatin-dependent mechanism. J Immunol 2003;170:2971-6. (Pubitemid 36302169)
21. Cavassani KA, Campanelli AP, Moreira AP, et al. Systemic and local characterization of regulatory T cells in a chronic fungal infection in humans. J Immunol 2006;177:5811-8. (Pubitemid 44628794)
22. Yamazaki S, Iyoda T, Tarbell K, et al. Direct expansion of functional CD25+ CD4+ regulatory T cells by antigen-processing dendritic cells. J Exp Med 2003;198:235-47. (Pubitemid 37009740)
23. Akbari O, Freeman GJ, Meyer EH, et al. Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity. Nat Med 2002;8:1024-32. (Pubitemid 35033708)
24. Chen W, Jin W, Hardegen N, et al. Conversion of peripheral CD4+. J Exp Med 2003;198:1875-86.
25. Baratelli F, Lin Y, Zhu L, et al. Prostaglandin E2 induces FOXP3 gene expression and T regulatory cell function in human CD4+ T cells. J Immunol 2005;175:1483-90. (Pubitemid 41023048)
26. Imamichi H, Sereti I, Lane HC. IL-15 acts as a potent inducer of CD4 (+) CD25 (hi) cells expressing FOXP3. Eur J Immunol 2008;38:1621-30.
27. Netea MG, Sutmuller R, Hermann C, et al. Toll-like receptor 2 suppresses immunity against Candida albicans through induction of IL-10 and regulatory T cells. J Immunol 2004;172:3712-8. (Pubitemid 38337955)
28. Riley JL. PD-1 signaling in primary T cells. Immunol Rev 2009;229:114-25.
29. Sharpe AH, Wherry EJ, Ahmed R, Freeman GJ. The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection. Nat Immunol 2007;8:239-45. (Pubitemid 46745373)
30. Wang L, Pino-Lagos K, de Vries VC, Guleria I, Sayegh MH, Noelle RJ. Programmed death 1 ligand signaling regulates the generation of adaptive Foxp3+CD4+ regulatory T cells. Proc Natl Acad Sci U S A 2008;105:9331-6.
31. Francisco LM, Salinas VH, Brown KE, et al. PD-L1 regulates the development, maintenance, and function of induced regulatory T cells. J Exp Med 2009;206:3015-29.
32. Franceschini D, Paroli M, Francavilla V, et al. PD-L1 negatively regulates CD4+CD25+Foxp3+ Tregs by limiting STAT-5 phosphorylation in patients chronically infected with HCV. J Clin Invest 2009;119:551-64.
33. Huber S, Schrader J, Fritz G, et al. P38 MAP kinase signaling is required for the conversion of CD4+. PLoS One 2008;3:e3302.
34. Koonpaew S, Shen S, Flowers L, Zhang W. LAT-mediated signaling in CD4+CD25+ regulatory T cell development. J Exp Med 2006;203:119-29. (Pubitemid 43139651)
35. Samon JB, Champhekar A, Minter LM, et al. Notch1 and TGFbeta1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T cells. Blood 2008;112:1813-21.
36. Ou-Yang HF, Zhang HW, Wu CG, et al. Notch signaling regulates the FOXP3 promoter through RBP-J-and Hes1-dependent mechanisms. Mol Cell Biochem 2009;320:109-14.
37. Kubo M, Hanada T, Yoshimura A. Suppressors of cytokine signaling and immunity. Nat Immunol 2003;4:1169-76. (Pubitemid 37540685)
38. Horino J, Fujimoto M, Terabe F, et al. Suppressor of cytokine signaling-1 ameliorates dextran sulfate sodium-induced colitis in mice. Int Immunol 2008;20:753-62. (Pubitemid 351791519)
39. Orr SJ, Morgan NM, Elliott J, et al. CD33 responses are blocked by SOCS3 through accelerated proteasomal-mediated turnover. Blood 2007;109:1061-8. (Pubitemid 46220652)
40. Chen S, Anderson PO, Li L, Sjogren HO, Wang P, Li SL. Functional association of cytokine-induced SH2 protein and protein kinase C in activated T cells. Int Immunol 2003;15:403-9. (Pubitemid 36336553)
41. Gupta S, Manicassamy S, Vasu C, Kumar A, Shang W, Sun Z. Differential requirement of PKC-theta in the development and function of natural regulatory T cells. Mol Immunol 2008;46:213-24.
42. Tone Y, Furuuchi K, Kojima Y, Tykocinski ML, Greene MI, Tone M. Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer. Nat Immunol 2008;9:194-202.
43. Burchill MA, Yang J, Vogtenhuber C, Blazar BR, Farrar MA. IL-2 receptor beta-dependent STAT5 activation is required for the development of Foxp3+ regulatory T cells. J Immunol 2007;178:280-90. (Pubitemid 46033611)
44. Kim HP, Leonard WJ. CREB/ATF-dependent T cell receptor-induced FoxP3 gene expression: a role for DNA methylation. J Exp Med 2007;204:1543-51. (Pubitemid 47048022)
45. Mantel PY, Ouaked N, Ruckert B, et al. Molecular mechanisms underlying FOXP3 induction in human T cells. J Immunol 2006;176:3593-602. (Pubitemid 43364007)
46. Takaki H, Ichiyama K, Koga K, et al. STAT6 inhibits TGF-beta1-mediated Foxp3 induction through direct binding to the Foxp3 promoter, which is reverted by retinoic acid receptor. J Biol Chem 2008;283:14955-62.
47. Guyot-Revol V, Innes JA, Hackforth S, Hinks T, Lalvani A. Regulatory T cells are expanded in blood and disease sites in patients with tuberculosis. Am J Respir Crit Care Med 2006;173:803-10.
48. Sharma PK, Saha PK, Singh A, Sharma SK, Ghosh B, Mitra DK. FoxP3+ regulatory T cells suppress effector T-cell function at pathologic site in miliary tuberculosis. Am J Respir Crit Care Med 2009;179:1061-70.
49. Shafiani S, Tucker-Heard G, Kariyone A, Takatsu K, Urdahl KB. Pathogen-specific regulatory T cells delay the arrival of effector T cells in the lung during early tuberculosis. J Exp Med 2010;207:1409-20.
50. Green AM, Mattila JT, Bigbee CL, Bongers KS, Lin PL, Flynn JL. CD4 (+) regulatory T cells in a cynomolgus macaque model of Mycobacterium tuberculosis infection. J Infect Dis 2010;202:533-41.