메뉴 건너뛰기




Volumn 30, Issue 3, 2011, Pages 182-188

Advancement and prospects of tumor gene therapy

Author keywords

Angiogenesis; Antisense RNA; Dendritic cells; Gene therapy; Non viral vector; Oxidative stress; RNA interference; Suicide gene; Tumor suppressor gene; Viral vector

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CYTOKINE; INTERLEUKIN 12; LIPOSOME; MINICIRCLE DNA; NAKED DNA; NANOPARTICLE; VIRUS VECTOR;

EID: 79954565713     PISSN: 1000467X     EISSN: 1944446X     Source Type: Journal    
DOI: 10.5732/cjc.010.10074     Document Type: Article
Times cited : (22)

References (77)
  • 1
    • 85036712432 scopus 로고    scopus 로고
    • http://en.wikipedia.org/wiki/Gene_therapy.
  • 2
    • 0028807727 scopus 로고
    • T lymphocyte-directed gene therapy for ADASC ID: Initial trial results after 4 years [J]
    • Blaese RM, Culver KW, Miller AD, et al. T lymphocyte-directed gene therapy for ADASC ID: initial trial results after 4 years [J]. Science, 1995,270(5235):475-480.
    • (1995) Science , vol.270 , Issue.5235 , pp. 475-480
    • Blaese, R.M.1    Culver, K.W.2    Miller, A.D.3
  • 3
    • 4444370799 scopus 로고    scopus 로고
    • Gene therapy clinical trials worldwide 19892004an overview [J]
    • Edelstein ML, Abedi MR, Wixon J, et al. Gene therapy clinical trials worldwide 19892004an overview [J]. J Gene Med, 2004,6 (6):597-602.
    • (2004) J Gene Med , vol.6 , Issue.6 , pp. 597-602
    • Edelstein, M.L.1    Abedi, M.R.2    Wixon, J.3
  • 4
    • 41949120595 scopus 로고    scopus 로고
    • Gene therapy: Some history, applications, problems, and prospects [J]
    • Cotrim AP, Baum BJ. Gene therapy: some history, applications, problems, and prospects [J]. Toxicol Pathology, 2008,36(1):97-103.
    • (2008) Toxicol Pathology , vol.36 , Issue.1 , pp. 97-103
    • Cotrim, A.P.1    Baum, B.J.2
  • 5
    • 0347365764 scopus 로고    scopus 로고
    • An overview of current delivery systems in cancer gene therapy [J]
    • El-Aneed A. An overview of current delivery systems in cancer gene therapy [J]. J Control Release, 2004,94(1):1-14.
    • (2004) J Control Release , vol.94 , Issue.1 , pp. 1-14
    • El-Aneed, A.1
  • 6
    • 33645540841 scopus 로고    scopus 로고
    • Nonvi ral vectors for cancer therapy [J]
    • Kaneda Y, Tabata Y. Nonvi ral vectors for cancer therapy [J]. Cancer Sci, 2006,97(5):348-354.
    • (2006) Cancer Sci , vol.97 , Issue.5 , pp. 348-354
    • Kaneda, Y.1    Tabata, Y.2
  • 7
    • 35348882024 scopus 로고    scopus 로고
    • Nanotechnology applications in cancer [J]
    • Nie S, Xing Y, Kim GJ, et al. Nanotechnology applications in cancer [J]. Annu Rev Biomed Eng, 2007,9:257-288.
    • (2007) Annu Rev Biomed Eng , vol.9 , pp. 257-288
    • Nie, S.1    Xing, Y.2    Kim, G.J.3
  • 8
    • 0037391751 scopus 로고    scopus 로고
    • Efficacy and safety of HLAB7 / beta-2 microglobulin plasmid DNA/lipid complex (Allovectin-7) in patients with metastatic melanoma [J]
    • Bergen M, Chen R, Gonzalez R. Efficacy and safety of HLAB7 / beta-2 microglobulin plasmid DNA/lipid complex (Allovectin-7) in patients with metastatic melanoma [J]. Expert Opin Biol Ther, 2003,3(2):377-384.
    • (2003) Expert Opin Biol Ther , vol.3 , Issue.2 , pp. 377-384
    • Bergen, M.1    Chen, R.2    Gonzalez, R.3
  • 9
    • 0742290161 scopus 로고    scopus 로고
    • Human gene therapy for malignant gliomas (glioblastoma multiforme and anaplastic astrocytoma) by in vivo transduction with human interferon beta gene using cationic liposomes [J]
    • Yoshida J, Mizuno M, Fujii M, et al. Human gene therapy for malignant gliomas (glioblastoma multiforme and anaplastic astrocytoma) by in vivo transduction with human interferon beta gene using cationic liposomes [J]. Hum Gene Ther, 2004,15(1): 77-86.
    • (2004) Hum Gene Ther , vol.15 , Issue.1 , pp. 77-86
    • Yoshida, J.1    Mizuno, M.2    Fujii, M.3
  • 10
    • 33749983751 scopus 로고    scopus 로고
    • Codelivery of drugs and DNA from cationic core-shell nanoparticles self-assembled from a biodegradable copolymer [J]
    • Wang Y, Gao S, Ye WH, et al. Codelivery of drugs and DNA from cationic core-shell nanoparticles self-assembled from a biodegradable copolymer [J]. Nat Mater, 2006,5(10):791-796.
    • (2006) Nat Mater , vol.5 , Issue.10 , pp. 791-796
    • Wang, Y.1    Gao, S.2    Ye, W.H.3
  • 11
    • 51049090204 scopus 로고    scopus 로고
    • Nanoparticle therapeutics: An emerging treatment modality for cancer [J]
    • Davis ME, Chen ZG, Shin DM. Nanoparticle therapeutics: an emerging treatment modality for cancer [J]. Nat Rev Drug Discov, 2008,7(9):771-782.
    • (2008) Nat Rev Drug Discov , vol.7 , Issue.9 , pp. 771-782
    • Davis, M.E.1    Chen, Z.G.2    Shin, D.M.3
  • 12
    • 67349190843 scopus 로고    scopus 로고
    • The use of folate-PEG-grafted-hybranched-PEI nonviral vector for the inhibition of glioma growth in the rat [J]
    • Liang B, He ML, Chan CY, et al. The use of folate-PEG-grafted-hybranched-PEI nonviral vector for the inhibition of glioma growth in the rat [J]. Biomaterials, 2009,30(23-24):4014-4020.
    • (2009) Biomaterials , vol.30 , Issue.23-24 , pp. 4014-4020
    • Liang, B.1    He, M.L.2    Chan, C.Y.3
  • 13
    • 42749091133 scopus 로고    scopus 로고
    • Polymer-drug conjugates: Recent development in clinical oncology [J]
    • Li C, Wallace S. Polymer-drug conjugates: recent development in clinical oncology [J]. Adv Drug Deliv Rev, 2008,60(8):886-898.
    • (2008) Adv Drug Deliv Rev , vol.60 , Issue.8 , pp. 886-898
    • Li, C.1    Wallace, S.2
  • 14
    • 42649145864 scopus 로고    scopus 로고
    • Poly (amino acid) micelle nanocarriers in preclinical and clinical studies [J]
    • Matsumura Y. Poly (amino acid) micelle nanocarriers in preclinical and clinical studies [J]. Adv Drug Deliv Rev, 2008,60(8):899-914.
    • (2008) Adv Drug Deliv Rev , vol.60 , Issue.8 , pp. 899-914
    • Matsumura, Y.1
  • 15
    • 33750626735 scopus 로고    scopus 로고
    • In vivo electroporation for gene therapy [J]
    • Heller LC, Heller R. In vivo electroporation for gene therapy [J]. Hum Gene Ther, 2006,17(9):890-897.
    • (2006) Hum Gene Ther , vol.17 , Issue.9 , pp. 890-897
    • Heller, L.C.1    Heller, R.2
  • 16
    • 5444270495 scopus 로고    scopus 로고
    • DNA electrotransfer: Its principles and an updated review of its therapeutic applications [J]
    • Andre F, Mir LM. DNA electrotransfer: its principles and an updated review of its therapeutic applications [J]. Gene Ther, 2004,11(Suppl 1):S33-S42.
    • (2004) Gene Ther , vol.11 , Issue.SUPPL. 1
    • Andre, F.1    Mir, L.M.2
  • 17
    • 58049200809 scopus 로고    scopus 로고
    • Phase I trial of interleukin-12 plasmid electroporation in patients with metastatic melanoma [J]
    • Daud AI, DeConti RC, Andrews S, et al. Phase I trial of interleukin-12 plasmid electroporation in patients with metastatic melanoma [J]. J Clin Oncol, 2008,26(36):5896-5903.
    • (2008) J Clin Oncol , vol.26 , Issue.36 , pp. 5896-5903
    • Daud, A.I.1    Deconti, R.C.2    Andrews, S.3
  • 18
    • 76749135226 scopus 로고    scopus 로고
    • Electroporation and ultrasound enhanced non-viral gene delivery in vitro and in vivo [J]
    • Wells DJ. Electroporation and ultrasound enhanced non-viral gene delivery in vitro and in vivo [J]. Cell Biol Toxicol, 2010,26(1):21-28.
    • (2010) Cell Biol Toxicol , vol.26 , Issue.1 , pp. 21-28
    • Wells, D.J.1
  • 19
    • 44249123015 scopus 로고    scopus 로고
    • Ultrasound mediated delivery of drugs and genes to solid tumors [J]
    • Frenkel V. Ultrasound mediated delivery of drugs and genes to solid tumors [J]. Adv Drug Deliv Rev, 2008,60(10):1193-1208.
    • (2008) Adv Drug Deliv Rev , vol.60 , Issue.10 , pp. 1193-1208
    • Frenkel, V.1
  • 20
    • 85036722438 scopus 로고    scopus 로고
    • Merk&Co. Whitehouse Station, NJ
    • Merk&Co. Whitehouse Station, NJ: http://www.merk.com.
  • 21
    • 11844304311 scopus 로고    scopus 로고
    • Spatial and temporal control of expression of therapeutic genes using heat shock protein promoters [J]
    • Rome C, Couillaud F, Moonen CT. Spatial and temporal control of expression of therapeutic genes using heat shock protein promoters [J]. Methods, 2005,35(2):188-198.
    • (2005) Methods , vol.35 , Issue.2 , pp. 188-198
    • Rome, C.1    Couillaud, F.2    Moonen, C.T.3
  • 22
    • 27744469013 scopus 로고    scopus 로고
    • High intensity focused ultrasound-induced gene activation in sublethally injured tumor cells in vitro [J]
    • Liu Y, Kon T, Li C, et al. High intensity focused ultrasound-induced gene activation in sublethally injured tumor cells in vitro [J]. J Acoust Soc Am, 2005,118(5):3328-3336.
    • (2005) J Acoust Soc Am , vol.118 , Issue.5 , pp. 3328-3336
    • Liu, Y.1    Kon, T.2    Li, C.3
  • 23
    • 33745737337 scopus 로고    scopus 로고
    • High intensity focused ultrasound-induced gene activation in solid tumors [J]
    • Liu Y, Kon T, Li C, et al. High intensity focused ultrasound-induced gene activation in solid tumors [J]. J Acoust Soc Am, 2006,120(1): 492-501.
    • (2006) J Acoust Soc Am , vol.120 , Issue.1 , pp. 492-501
    • Liu, Y.1    Kon, T.2    Li, C.3
  • 24
    • 33751001045 scopus 로고    scopus 로고
    • Microbubble-enhanced ultrasound to deliver an antisense oligodeoxynucleotide targeting the human androgen receptor into prostate tumours [J]
    • Haag P, Frauscher F, Gradl J, et al. Microbubble-enhanced ultrasound to deliver an antisense oligodeoxynucleotide targeting the human androgen receptor into prostate tumours [J]. J Steroid Biochem Mol Biol, 2006,102(1-5):103-113.
    • (2006) J Steroid Biochem Mol Biol , vol.102 , Issue.1-5 , pp. 103-113
    • Haag, P.1    Frauscher, F.2    Gradl, J.3
  • 25
    • 0037314610 scopus 로고    scopus 로고
    • A phase I/II trial of intratumoral endoscopic ultrasound injection of ONYX015 with intravenous gemcitabine in unresectable pancreatic carcinoma [J]
    • Hecht JR, Bedford R, Abbruzzese JL, et al. A phase I/II trial of intratumoral endoscopic ultrasound injection of ONYX015 with intravenous gemcitabine in unresectable pancreatic carcinoma [J]. Clin Cancer Res, 2003,9(2):555-561.
    • (2003) Clin Cancer Res , vol.9 , Issue.2 , pp. 555-561
    • Hecht, J.R.1    Bedford, R.2    Abbruzzese, J.L.3
  • 26
    • 0032805251 scopus 로고    scopus 로고
    • Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA [J]
    • Liu F, Song Y, Liu D. Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA [J]. Gene Ther, 1999,6(7):1258-1266.
    • (1999) Gene Ther , vol.6 , Issue.7 , pp. 1258-1266
    • Liu, F.1    Song, Y.2    Liu, D.3
  • 27
    • 0027140509 scopus 로고
    • DNA vaccines: Protective immunizations by parenteral, mucosal, and gene-gun inoculations [J]
    • Fynan EF, Webster RG, Fuller DH, et al. DNA vaccines: protective immunizations by parenteral, mucosal, and gene-gun inoculations [J]. Proc Natl Acad Sci USA, 1993,90(24):11478-11482.
    • (1993) Proc Natl Acad Sci USA , vol.90 , Issue.24 , pp. 11478-11482
    • Fynan, E.F.1    Webster, R.G.2    Fuller, D.H.3
  • 28
    • 0031436820 scopus 로고    scopus 로고
    • A new DNA vehicle for nonviral gene delivery: Supercoiled minicircle [J]
    • Darquet AM, Cameron B, Wils P, et al. A new DNA vehicle for nonviral gene delivery: supercoiled minicircle [J]. Gene Ther, 1997,4(12):1341-1349.
    • (1997) Gene Ther , vol.4 , Issue.12 , pp. 1341-1349
    • Darquet, A.M.1    Cameron, B.2    Wils, P.3
  • 29
    • 0041315884 scopus 로고    scopus 로고
    • Minicircle DNA vectors devoid of bacterial DNA result in persistent and high-level transgene expression in vivo [J]
    • Chen ZY, He CY, Ehrhardt A, et al. Minicircle DNA vectors devoid of bacterial DNA result in persistent and high-level transgene expression in vivo [J]. Mol Ther, 2003,8(3):495-500.
    • (2003) Mol Ther , vol.8 , Issue.3 , pp. 495-500
    • Chen, Z.Y.1    He, C.Y.2    Ehrhardt, A.3
  • 30
    • 13844292517 scopus 로고    scopus 로고
    • Improved production and purification of minicircle DNA vector free of plasmid bacterial sequences and capable of persistent transgene expression in vivo [J]
    • Chen ZY, He CY, Kay MA. Improved production and purification of minicircle DNA vector free of plasmid bacterial sequences and capable of persistent transgene expression in vivo [J]. Hum Gene Ther, 2005,16(1):126-131.
    • (2005) Hum Gene Ther , vol.16 , Issue.1 , pp. 126-131
    • Chen, Z.Y.1    He, C.Y.2    Kay, M.A.3
  • 31
    • 0035933760 scopus 로고    scopus 로고
    • An araC-controlled bacterial cre expression system to produce DNA minicircle vectors for nuclear and itochondrial gene therapy [J]
    • Bigger BW, Tolmachov O, Collombet JM, et al. An araC-controlled bacterial cre expression system to produce DNA minicircle vectors for nuclear and itochondrial gene therapy [J]. J Biol Chem, 2001,276(25):23018-23027.
    • (2001) J Biol Chem , vol.276 , Issue.25 , pp. 23018-23027
    • Bigger, B.W.1    Tolmachov, O.2    Collombet, J.M.3
  • 32
    • 0033023054 scopus 로고    scopus 로고
    • Minicircle: An improved DNA molecule for in vitro and in vivo gene transfer [J]
    • Darquet AM, Rangara R, Kreiss P, et al. Minicircle: an improved DNA molecule for in vitro and in vivo gene transfer [J]. Gene Ther, 1999,6(2):209-218.
    • (1999) Gene Ther , vol.6 , Issue.2 , pp. 209-218
    • Darquet, A.M.1    Rangara, R.2    Kreiss, P.3
  • 33
    • 33748050464 scopus 로고    scopus 로고
    • Minicircle-IFNgamma induces antiproliferative and antitumoral effects in human nasopharyngeal carcinoma [J]
    • Wu J, Xiao X, Zhao P, et al. Minicircle-IFNgamma induces antiproliferative and antitumoral effects in human nasopharyngeal carcinoma [J]. Clin Cancer Res, 2006,12(15):4702-4713.
    • (2006) Clin Cancer Res , vol.12 , Issue.15 , pp. 4702-4713
    • Wu, J.1    Xiao, X.2    Zhao, P.3
  • 34
    • 85036722843 scopus 로고    scopus 로고
    • http://www.sibiono.com/en/introduce.html.
  • 35
    • 0029856574 scopus 로고    scopus 로고
    • Adenoviralmediated wild type p53 gene expression sensitizes colorectal cancer cells to ionizing radiation [J]
    • Spitz FR, Nguyen D, Skibber JM, et al. Adenoviralmediated wild type p53 gene expression sensitizes colorectal cancer cells to ionizing radiation [J]. Clin Cancer Res, 1996,2(10):1665-1671.
    • (1996) Clin Cancer Res , vol.2 , Issue.10 , pp. 1665-1671
    • Spitz, F.R.1    Nguyen, D.2    Skibber, J.M.3
  • 36
    • 0036181023 scopus 로고    scopus 로고
    • Cancer gene therapy: Scientific basis [J]
    • Wadhwa PD, Zielske SP, Roth JC, et al. Cancer gene therapy: scientific basis [J]. Annu Rev Med, 2002,53:437-452.
    • (2002) Annu Rev Med , vol.53 , pp. 437-452
    • Wadhwa, P.D.1    Zielske, S.P.2    Roth, J.C.3
  • 37
    • 52149089437 scopus 로고    scopus 로고
    • Prodrug cancer gene therapy [J]
    • Altaner C. Prodrug cancer gene therapy [J]. Cancer Lett, 2008,270 (2):191-201.
    • (2008) Cancer Lett , vol.270 , Issue.2 , pp. 191-201
    • Altaner, C.1
  • 38
    • 0038685423 scopus 로고    scopus 로고
    • Prodrugs for Gene-Directed Enzyme-Prodrug Therapy (Suicide Gene Therapy) [J]
    • Denny WA. Prodrugs for Gene-Directed Enzyme-Prodrug Therapy (Suicide Gene Therapy) [J]. J Biomed Biotechnol, 2003,2003(1): 48-70.
    • (2003) J Biomed Biotechnol , vol.2003 , Issue.1 , pp. 48-70
    • Denny, W.A.1
  • 39
    • 0031437780 scopus 로고    scopus 로고
    • A cell surface tethered enzyme improves efficiency in gene-directed enzyme prodrug therapy [J]
    • Marais R, Spooner RA, Stribbling SM, et al. A cell surface tethered enzyme improves efficiency in gene-directed enzyme prodrug therapy [J]. Nat Biotechnol, 1997,15(13):1373-1377.
    • (1997) Nat Biotechnol , vol.15 , Issue.13 , pp. 1373-1377
    • Marais, R.1    Spooner, R.A.2    Stribbling, S.M.3
  • 41
    • 0036045454 scopus 로고    scopus 로고
    • Hydroxyurea significantly enhances tumor growth delay in vivo with herpes simplex virus thymidine kinase/ganciclovir gene therapy [J]
    • Boucher PD, Ostruszka LJ, Murphy PJ, et al. Hydroxyurea significantly enhances tumor growth delay in vivo with herpes simplex virus thymidine kinase/ganciclovir gene therapy [J]. Gene Ther, 2002,9(15):1023-1030.
    • (2002) Gene Ther , vol.9 , Issue.15 , pp. 1023-1030
    • Boucher, P.D.1    Ostruszka, L.J.2    Murphy, P.J.3
  • 42
    • 0034654516 scopus 로고    scopus 로고
    • Synergistic enhancement of herpes simplex virus thymidine kinase/ganciclovir-mediated cytoxicity by hydroxyurea [J]
    • Boucher PD, Ostruszka LJ, Shewach DS. Synergistic enhancement of herpes simplex virus thymidine kinase/ganciclovir-mediated cytoxicity by hydroxyurea [J]. Cancer Res, 2000,60(6):1631-1636.
    • (2000) Cancer Res , vol.60 , Issue.6 , pp. 1631-1636
    • Boucher, P.D.1    Ostruszka, L.J.2    Shewach, D.S.3
  • 43
    • 0030937485 scopus 로고    scopus 로고
    • Gap junctions promote the bystander effect of herpes simplex virus thymidine kinase in vivo [J]
    • Dilber MS, Abedi MR, Christensson B, et al. Gap junctions promote the bystander effect of herpes simplex virus thymidine kinase in vivo [J]. Cancer Res, 1997,57(8):1523-1528.
    • (1997) Cancer Res , vol.57 , Issue.8 , pp. 1523-1528
    • Dilber, M.S.1    Abedi, M.R.2    Christensson, B.3
  • 44
    • 33847247850 scopus 로고    scopus 로고
    • Antiangiogenic gene therapy of cancer: Current status and future prospects [J]
    • ersano L, Crescenzi M, Indraccolo S. Antiangiogenic gene therapy of cancer: current status and future prospects [J]. Mol Aspects Med, 2007,28(1):87-114.
    • (2007) Mol Aspects Med , vol.28 , Issue.1 , pp. 87-114
    • Ersano, L.1    Crescenzi, M.2    Indraccolo, S.3
  • 45
    • 33645213896 scopus 로고    scopus 로고
    • Adenovirusm ediated intratumoral delivery of the human endostatin gene inhibits tumor growth in nasopharyngeal carcinoma [J]
    • Li L, Liu RY, Huang JL, et al. Adenovirusm ediated intratumoral delivery of the human endostatin gene inhibits tumor growth in nasopharyngeal carcinoma [J]. Int J Cancer, 2006,118(8):2064-2071.
    • (2006) Int J Cancer , vol.118 , Issue.8 , pp. 2064-2071
    • Li, L.1    Liu, R.Y.2    Huang, J.L.3
  • 46
    • 67650744372 scopus 로고    scopus 로고
    • Immune therapy for cancer [J]
    • Dougan M, Dranoff G. Immune therapy for cancer [J]. Annu Rev Immunol, 2009,27:83-117.
    • (2009) Annu Rev Immunol , vol.27 , pp. 83-117
    • Dougan, M.1    Dranoff, G.2
  • 47
    • 77949424738 scopus 로고    scopus 로고
    • PhaseI clinical trial of IL-12 plasmid/lipopolymer complexes for the treatment of recurrent ovarian cancer [J]
    • Anwer K, Barnes MN, Fewell J, et al. PhaseI clinical trial of IL-12 plasmid/lipopolymer complexes for the treatment of recurrent ovarian cancer [J]. Gene Ther, 2009,17(3):360-369.
    • (2009) Gene Ther , vol.17 , Issue.3 , pp. 360-369
    • Anwer, K.1    Barnes, M.N.2    Fewell, J.3
  • 48
    • 85036721484 scopus 로고    scopus 로고
    • http://clinicaltrials.gov/ct2/show/NCT00406939.
  • 49
    • 0028966431 scopus 로고
    • A novel cancer therapy based on oxygen radicals [J]
    • Yoshikawa T, Kokura S, Tainaka K, et al. A novel cancer therapy based on oxygen radicals [J]. Cancer Res, 1995,55(8):1617-1620.
    • (1995) Cancer Res , vol.55 , Issue.8 , pp. 1617-1620
    • Yoshikawa, T.1    Kokura, S.2    Tainaka, K.3
  • 50
    • 0034699513 scopus 로고    scopus 로고
    • Superoxide dismutase as a target for the selective killing of cancer cells [J]
    • Huang P, Feng L, Oldham EA, et al. Superoxide dismutase as a target for the selective killing of cancer cells [J]. Nature, 2000,407(6802):390-395.
    • (2000) Nature , vol.407 , Issue.6802 , pp. 390-395
    • Huang, P.1    Feng, L.2    Oldham, E.A.3
  • 51
    • 64149087422 scopus 로고    scopus 로고
    • Therapeutic strategies by modulating oxygen stress in cancer and inflammation [J]
    • Fang J, Seki T, Maeda H. Therapeutic strategies by modulating oxygen stress in cancer and inflammation [J]. Adv Drug Deliv Rev, 2009,61(4):290-302.
    • (2009) Adv Drug Deliv Rev , vol.61 , Issue.4 , pp. 290-302
    • Fang, J.1    Seki, T.2    Maeda, H.3
  • 52
    • 0032548411 scopus 로고    scopus 로고
    • Induction of cytotoxic oxidative stress by Dal anine in brain tumor cells expressing Rhodotorula gracilis D-am ino acid oxidase: A cancer gene therapy strategy [J]
    • Stegman LD, Zheng H, Neal ER, et al. Induction of cytotoxic oxidative stress by Dal anine in brain tumor cells expressing Rhodotorula gracilis D-am ino acid oxidase: a cancer gene therapy strategy [J]. Hum Gene Tther, 1998,9(2):185-193.
    • (1998) Hum Gene Tther , vol.9 , Issue.2 , pp. 185-193
    • Stegman, L.D.1    Zheng, H.2    Neal, E.R.3
  • 53
    • 0038418359 scopus 로고    scopus 로고
    • In vivo antitumor activity of pegylated zinc protoporphyrin: Targeted inhibition of heme oxygenase in solid tumor [J]
    • Fang J, Sawa T, Akaike T, et al. In vivo antitumor activity of pegylated zinc protoporphyrin: targeted inhibition of heme oxygenase in solid tumor [J]. Cancer Res, 2003,63(13):3567-3574.
    • (2003) Cancer Res , vol.63 , Issue.13 , pp. 3567-3574
    • Fang, J.1    Sawa, T.2    Akaike, T.3
  • 54
    • 33847036990 scopus 로고    scopus 로고
    • Strategies for silencing human disease using RNA interference [J]
    • Kim DH, Rossi JJ. Strategies for silencing human disease using RNA interference [J]. Nat Rev Genet, 2007,8(3):173-184.
    • (2007) Nat Rev Genet , vol.8 , Issue.3 , pp. 173-184
    • Kim, D.H.1    Rossi, J.J.2
  • 55
    • 43249091971 scopus 로고    scopus 로고
    • RNA interference and cancer: Endogenous pathways and therapeutic approaches [J]
    • Dykxhoorn DM, Chowdhury D, Lieberman J. RNA interference and cancer: endogenous pathways and therapeutic approaches [J]. Adv Exp Med Biol, 2008,615:299-329.
    • (2008) Adv Exp Med Biol , vol.615 , pp. 299-329
    • Dykxhoorn, D.M.1    Chowdhury, D.2    Lieberman, J.3
  • 56
    • 16244377103 scopus 로고    scopus 로고
    • A crucial test [J]
    • Check E. A crucial test [J]. Nature medicine, 2005,11(3):243-244.
    • (2005) Nature Medicine , vol.11 , Issue.3 , pp. 243-244
    • Check, E.1
  • 57
    • 1542306855 scopus 로고    scopus 로고
    • Interferon induction by siRNAs and ssRNAs synthesized by phage polymerase [J]
    • Kim DH, Longo M, Han Y, et al. Interferon induction by siRNAs and ssRNAs synthesized by phage polymerase [J]. Nat Biotechnol, 2004,22(3):321-325.
    • (2004) Nat Biotechnol , vol.22 , Issue.3 , pp. 321-325
    • Kim, D.H.1    Longo, M.2    Han, Y.3
  • 58
    • 33646848909 scopus 로고    scopus 로고
    • RNAi as a treatment for HIV1 infection [J]
    • Rossi JJ. RNAi as a treatment for HIV1 infection [J]. BioTechniques, 2006,40(S4):S25-S29.
    • (2006) BioTechniques , vol.40 , Issue.S4
    • Rossi, J.J.1
  • 59
    • 69849096670 scopus 로고    scopus 로고
    • Antisense gapmers selectively suppress individual oncogenic p73 splice isoforms and inhibit tumor growth in vivo [J]
    • Emmrich S, Wang W, John K, et al. Antisense gapmers selectively suppress individual oncogenic p73 splice isoforms and inhibit tumor growth in vivo [J]. Mol Cancer, 2009,8:61.
    • (2009) Mol Cancer , vol.8 , pp. 61
    • Emmrich, S.1    Wang, W.2    John, K.3
  • 60
    • 67650403364 scopus 로고    scopus 로고
    • Controlled delivery of antisense oligonucleotides: A brief review of current strategies [J]
    • Zhao X, Pan F, Holt CM, et al. Controlled delivery of antisense oligonucleotides: a brief review of current strategies [J]. Expert Opin Drug Deliv, 2009,6(7):673-686.
    • (2009) Expert Opin Drug Deliv , vol.6 , Issue.7 , pp. 673-686
    • Zhao, X.1    Pan, F.2    Holt, C.M.3
  • 61
    • 32644456874 scopus 로고    scopus 로고
    • Antiviral innate immunity pathways [J]
    • Seth RB, Sun L, Chen ZJ. Antiviral innate immunity pathways [J]. Cell Res, 2006,16(2):141-147.
    • (2006) Cell Res , vol.16 , Issue.2 , pp. 141-147
    • Seth, R.B.1    Sun, L.2    Chen, Z.J.3
  • 62
    • 36849026128 scopus 로고    scopus 로고
    • Applications of RNA interference in mammalian systems [J]
    • Martin SE, Caplen NJ. Applications of RNA interference in mammalian systems [J]. Ann Rev Genom Hum G, 2007,8:81-108.
    • (2007) Ann Rev Genom Hum G , vol.8 , pp. 81-108
    • Martin, S.E.1    Caplen, N.J.2
  • 63
    • 29144509665 scopus 로고    scopus 로고
    • Drosophila microRNAs exhibit diverse spatial expression patterns during embryonic development [J]
    • Aboobaker AA, Tomancak P, Patel N, et al. Drosophila microRNAs exhibit diverse spatial expression patterns during embryonic development [J]. Proc Natl Acad Sci USA, 2005,102(50):18017-18022.
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.50 , pp. 18017-18022
    • Aboobaker, A.A.1    Tomancak, P.2    Patel, N.3
  • 64
    • 27644469434 scopus 로고    scopus 로고
    • Spatial regulation of microRNA gene expression in the Drosophila embryo [J]
    • Biemar F, Zinzen R, Ronshaugen M, et al. Spatial regulation of microRNA gene expression in the Drosophila embryo [J]. Proc Natl Acad Sci USA, 2005,102(44):15907-15911.
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.44 , pp. 15907-15911
    • Biemar, F.1    Zinzen, R.2    Ronshaugen, M.3
  • 65
    • 74549174260 scopus 로고    scopus 로고
    • Dendritic cellbased cancer gene therapy [J]
    • Smits EL, Anguille S, Cools N, et al. Dendritic cellbased cancer gene therapy [J]. Hum Gene Ther, 2009,20(10):1106-1108.
    • (2009) Hum Gene Ther , vol.20 , Issue.10 , pp. 1106-1108
    • Smits, E.L.1    Anguille, S.2    Cools, N.3
  • 66
    • 33746900019 scopus 로고    scopus 로고
    • Immunogene therapy of cancer with tumour-mRNA transfected dendritic cells [J]
    • Kyte JA, Gaudernack G. Immunogene therapy of cancer with tumour-mRNA transfected dendritic cells [J]. Cancer Immunol Immunother, 2006,55(11):1432-1442.
    • (2006) Cancer Immunol Immunother , vol.55 , Issue.11 , pp. 1432-1442
    • Kyte, J.A.1    Gaudernack, G.2
  • 67
    • 0034962640 scopus 로고    scopus 로고
    • Adenovirusmediated CD40 ligand gene therapy in a rat model of orthotopic hepatocellular carcinoma [J]
    • Schmitz V, Barajas M, Wang L, et al. Adenovirusmediated CD40 ligand gene therapy in a rat model of orthotopic hepatocellular carcinoma [J]. Hepatology, 2001,34(1):72-81.
    • (2001) Hepatology , vol.34 , Issue.1 , pp. 72-81
    • Schmitz, V.1    Barajas, M.2    Wang, L.3
  • 68
    • 0042526005 scopus 로고    scopus 로고
    • Gene therapy to target dendritic cells from blood to lymph nodes [J]
    • Robert C, Klein C, Cheng G, et al. Gene therapy to target dendritic cells from blood to lymph nodes [J]. Gene Ther, 2003,10 (17): 1479-1486.
    • (2003) Gene Ther , vol.10 , Issue.17 , pp. 1479-1486
    • Robert, C.1    Klein, C.2    Cheng, G.3
  • 69
    • 13644263499 scopus 로고    scopus 로고
    • Comparative analysis of dendritic cells transduced with different anti-apoptotic molecules: Sensitivity to tumorinduced apoptosis [J]
    • Balkir L, Tourkova IL, Makarenkova VP, et al. Comparative analysis of dendritic cells transduced with different anti-apoptotic molecules: sensitivity to tumorinduced apoptosis [J]. J Gene Med, 2004,6(5):537-544.
    • (2004) J Gene Med , vol.6 , Issue.5 , pp. 537-544
    • Balkir, L.1    Tourkova, I.L.2    Makarenkova, V.P.3
  • 70
    • 34249868241 scopus 로고    scopus 로고
    • Adoptive T cell therapy for cancer in the clinic [J]
    • June CH. Adoptive T cell therapy for cancer in the clinic [J]. J Clin Invest, 2007,117(6):1466-1476.
    • (2007) J Clin Invest , vol.117 , Issue.6 , pp. 1466-1476
    • June, C.H.1
  • 71
    • 70149114880 scopus 로고    scopus 로고
    • Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen [J]
    • Johnson LA, Morgan RA, Dudley ME, et al. Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen [J]. Blood, 2009,114(3): 535-546.
    • (2009) Blood , vol.114 , Issue.3 , pp. 535-546
    • Johnson, L.A.1    Morgan, R.A.2    Dudley, M.E.3
  • 72
    • 0036635506 scopus 로고    scopus 로고
    • T-cell-receptor gene therapy [J]
    • Schumacher TN. T-cell-receptor gene therapy [J]. Nat Rev Immunol, 2002,2(7):512-519.
    • (2002) Nat Rev Immunol , vol.2 , Issue.7 , pp. 512-519
    • Schumacher, T.N.1
  • 73
    • 0035159470 scopus 로고    scopus 로고
    • Redirecting mouse CTL against colon carcinoma: Superior signaling efficacy of single-chain variable domain chimeras containing TCRzeta vs Fc epsilon RI-gamma [J]
    • Haynes NM, Snook MB, Trapani JA, et al. Redirecting mouse CTL against colon carcinoma: superior signaling efficacy of single-chain variable domain chimeras containing TCRzeta vs Fc epsilon RI-gamma [J]. J Immunol, 2001,166(1):182-187.
    • (2001) J Immunol , vol.166 , Issue.1 , pp. 182-187
    • Haynes, N.M.1    Snook, M.B.2    Trapani, J.A.3
  • 74
    • 0032589575 scopus 로고    scopus 로고
    • The role of CCR7 in TH1 and TH2 cell localization and delivery of B cell help in vivo [J]
    • Randolph DA, Huang G, Carruthers CJ, et al. The role of CCR7 in TH1 and TH2 cell localization and delivery of B cell help in vivo [J]. Science, 1999,286(5447):2159-2162.
    • (1999) Science , vol.286 , Issue.5447 , pp. 2159-2162
    • Randolph, D.A.1    Huang, G.2    Carruthers, C.J.3
  • 75
    • 0033543128 scopus 로고    scopus 로고
    • Expression of chimeric granulocyte-macrophage colony-stimulating factor/interleukin 2 receptors in human cytotoxic T lymphocyte clones results in granulocyte-macrophage colony-stimulating factor-dependent growth [J]
    • Evans LS, Witte PR, Feldhaus AL, et al. Expression of chimeric granulocyte-macrophage colony-stimulating factor/interleukin 2 receptors in human cytotoxic T lymphocyte clones results in granulocyte-macrophage colony-stimulating factor-dependent growth [J]. Hum Gene Ther, 1999,10(12):1941-1951.
    • (1999) Hum Gene Ther , vol.10 , Issue.12 , pp. 1941-1951
    • Evans, L.S.1    Witte, P.R.2    Feldhaus, A.L.3
  • 76
    • 65249096622 scopus 로고    scopus 로고
    • Preclinical development of T cell receptor gene therapy [J]
    • Bendle GM, Haanen JB, Schumacher TN. Preclinical development of T cell receptor gene therapy [J]. Curr Opin Immunol, 2009,21(2): 209-214.
    • (2009) Curr Opin Immunol , vol.21 , Issue.2 , pp. 209-214
    • Bendle, G.M.1    Haanen, J.B.2    Schumacher, T.N.3
  • 77
    • 54249148553 scopus 로고    scopus 로고
    • Balancing between antitumor efficacy and autoimmune pathology in T-cell-mediated targeting of carcinoembryonic antigen [J]
    • Bos R, van Duikeren S, Morreau H, et al. Balancing between antitumor efficacy and autoimmune pathology in T-cell-mediated targeting of carcinoembryonic antigen [J]. Cancer Res, 2008,68 (20):8446-8455.
    • (2008) Cancer Res , vol.68 , Issue.20 , pp. 8446-8455
    • Bos, R.1    van Duikeren, S.2    Morreau, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.