Antisense gapmers selectively suppress individual oncogenic p73 splice isoforms and inhibit tumor growth in vivo

Molecular Cancer

Volumn 8, Issue , 2009, Pages

  Emmrich, Stephan ^a   Wang, Weiwei ^a   John, Katja ^a   Li, Wenzhong ^a   Pützer, Brigitte M ^a  

^a UNIVERSITY OF ROSTOCK   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; LOCKED NUCLEIC ACID; POLYETHYLENEIMINE DERIVATIVE; PROTEIN P73; SHORT HAIRPIN RNA; DNA BINDING PROTEIN; GREEN FLUORESCENT PROTEIN; ISOPROTEIN; MESSENGER RNA; NUCLEAR PROTEIN; SMALL INTERFERING RNA; TUMOR SUPPRESSOR PROTEIN; TUMOR SUPPRESSOR PROTEIN P73;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER INHIBITION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG DESIGN; DRUG EFFICACY; DRUG SPECIFICITY; DRUG TARGETING; EXON; FEMALE; GENE OVEREXPRESSION; GENE REPRESSION; HUMAN; HUMAN CELL; IN VIVO STUDY; MELANOMA; MOUSE; NONHUMAN; NUCLEIC ACID ANALYSIS; RNA SPLICING; WILD TYPE; ALTERNATIVE RNA SPLICING; ANIMAL; CELL LINE; DRUG SCREENING; EXPERIMENTAL MELANOMA; FLUORESCENCE MICROSCOPY; GENETIC TRANSFECTION; GENETICS; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; NUDE MOUSE; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL LINE; TUMOR VOLUME; WESTERN BLOTTING;

ALTERNATIVE SPLICING; ANIMALS; APOPTOSIS; BASE SEQUENCE; BLOTTING, WESTERN; CELL LINE; CELL LINE, TUMOR; DNA-BINDING PROTEINS; FEMALE; GREEN FLUORESCENT PROTEINS; HUMANS; MELANOMA, EXPERIMENTAL; MICE; MICE, NUDE; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; OLIGONUCLEOTIDES, ANTISENSE; PROTEIN ISOFORMS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; TRANSFECTION; TUMOR BURDEN; TUMOR SUPPRESSOR PROTEINS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 69849096670     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-8-61     Document Type: Article

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