In vivo antitumor activity of pegylated zinc protoporphyrin: Targeted inhibition of heme oxygenase in solid tumor

Cancer Research

Volumn 63, Issue 13, 2003, Pages 3567-3574

  Fang, Jun ^a   Sawa, Tomohiro ^a,c   Akaike, Takaaki ^a   Akuta, Teruo ^a   Sahoo, Sanjeeb K ^a   Khaled, Greish ^a   Hamada, Akinobu ^b   Maeda, Hiroshi ^a  

^a KUMAMOTO UNIV SCHOOL OF MEDICINE   (Japan)

^b KUMAMOTO UNIVERSITY   (Japan)

^c INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

HEME OXYGENASE; MACROGOL; PEGYLATED ZINC PROTOPORPHYRIN; PROTOPORPHYRIN ZINC; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACCUMULATION; DRUG CONJUGATION; DRUG EFFECT; DRUG MECHANISM; DRUG PENETRATION; DRUG POTENCY; DRUG RETENTION; DRUG TARGETING; DRUG TISSUE LEVEL; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SOLID TUMOR;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; COLONIC NEOPLASMS; ENZYME INHIBITORS; HEME OXYGENASE (DECYCLIZING); HEME OXYGENASE-1; HUMANS; IN SITU NICK-END LABELING; MALE; MEMBRANE PROTEINS; METALLOPORPHYRINS; MICE; MICE, INBRED STRAINS; POLYETHYLENE GLYCOLS; SARCOMA, EXPERIMENTAL; TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED;

EID: 0038418359     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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