Regulation of insulin-regulated membrane aminopeptidase activity by its C-terminal domain

Biochemistry

Volumn 50, Issue 13, 2011, Pages 2611-2622

  Ascher, David B ^a   Cromer, Brett A ^a   Morton, Craig J ^a   Volitakis, Irene ^b,c   Cherny, Robert A ^b,c   Albiston, Anthony L ^b   Chai, Siew Yeen ^b   Parker, Michael W ^a,d  

^a ST VINCENT'S INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c FLOREY INSTITUTE OF NEUROSCIENCE AND MENTAL HEALTH   (Australia)

^d UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; ALZHEIMER'S DISEASE; AMINO PEPTIDASE; BIOCHEMICAL PROPERTIES; C-TERMINAL DOMAINS; CONFORMATIONAL CHANGE; DIMER INTERFACE; DOMAIN BOUNDARY; EXTRACELLULAR; EXTRACELLULAR REGION; HOMOLOGY MODELS; MEMBRANE-BOUND; MEMORY LOSS; METALLOPEPTIDASES; PARTIAL PROTEOLYSIS; SECONDARY STRUCTURE PREDICTION; SEQUENCE ALIGNMENTS;

BINDING SITES; INSULIN; MASS SPECTROMETRY; ZINC;

DISEASES;

AMINOPEPTIDASE; ANGIOTENSIN II [3-8]; DIMER; INSULIN REGULATED MEMBRANE AMINOPEPTIDASE; METALLOPROTEINASE; UNCLASSIFIED DRUG; ZINC ION;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CHEMICAL ANALYSIS; CONTROLLED STUDY; DIMERIZATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME KINETICS; ENZYME REGULATION; EXTRACELLULAR MATRIX; FRAGMENTATION REACTION; ISOTOPE LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN PURIFICATION;

ALZHEIMER DISEASE; ANGIOTENSIN II; BINDING SITES; CATALYTIC DOMAIN; CYSTINYL AMINOPEPTIDASE; DATABASES, PROTEIN; HUMANS; HYDROLYSIS; KINETICS; MODELS, MOLECULAR; MOLECULAR TARGETED THERAPY; PEPTIDE FRAGMENTS; PROTEASE INHIBITORS; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY; ZINC;

EID: 79953166764     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi101893w     Document Type: Article

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