The C-terminal domain, but not the interchain disulphide, is required for the activity and intracellular trafficking of aminopeptidase A

Biochemical Journal

Volumn 362, Issue 1, 2002, Pages 191-197

  Ofner, Lisa D ^a   Hooper, Nigel M ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

Aminopeptidase N; COS cells; Ectoenzyme; Pro domain; Zinc metallopeptidase

Indexed keywords

BIOLOGICAL MEMBRANES; CATALYSIS; CELLS; ENZYME KINETICS; FLUORESCENCE; IMMUNOLOGY; MICROSCOPIC EXAMINATION; PROTEINS;

INTERCELLULAR TRAFFICKING;

BIOCHEMISTRY;

GLUTAMYL AMINOPEPTIDASE;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DISULFIDE BOND; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME LOCALIZATION; INTRACELLULAR TRANSPORT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN TRANSPORT;

AMINOPEPTIDASES; ANIMALS; COS CELLS; DISULFIDES; GLUTAMYL AMINOPEPTIDASE; MICROSCOPY, FLUORESCENCE; PROTEIN TRANSPORT;

ANIMALIA; MAMMALIA; MURINAE;

EID: 0037084123     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3620191     Document Type: Article

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