Inhibition of insulin-like growth factor I activity contributes to the premature apoptosis of cerebellar granule neuron in weaver mutant mice: In vitro analysis

Journal of Neuroscience Research

Volumn 70, Issue 1, 2002, Pages 36-45

  Zhong, Jin ^a   Deng, Jixian ^a   Ghetti, Bernardino ^a   Lee, Wei Hua ^a,b  

^a INDIANA UNIVERSITY   (United States)

^b INDIANA UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Apoptosis; Caspase 3; Insulin like growth factor I; PI3 Akt; Weaver mice

Indexed keywords

PROTEIN KINASE B; SOMATOMEDIN BINDING PROTEIN 5; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; GRANULE CELL; MOUSE; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

ANALYSIS OF VARIANCE; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CASPASE 3; CASPASES; CELL SURVIVAL; CELLS, CULTURED; CEREBELLUM; GENOTYPE; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 5; INSULIN-LIKE GROWTH FACTOR I; MICE; MICE, MUTANT STRAINS; MICE, NEUROLOGIC MUTANTS; NEURONS; ONCOGENE PROTEINS; PHOSPHORYLATION; POINT MUTATION; POTASSIUM CHANNELS; PRECIPITIN TESTS; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, IGF TYPE 1; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 0036786241     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.10360     Document Type: Article

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