메뉴 건너뛰기




Volumn 2, Issue 1, 2010, Pages 22-29

IRAK-M regulation and function in host defense and immune homeostasis

Author keywords

Immune regulation; Inflammation; Sepsis

Indexed keywords

B7 ANTIGEN; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 3; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR; TRANSCRIPTION FACTOR AP 1;

EID: 79952505326     PISSN: None     EISSN: 20367449     Source Type: Journal    
DOI: 10.4081/idr.2010.e9     Document Type: Article
Times cited : (65)

References (74)
  • 1
    • 62649124147 scopus 로고    scopus 로고
    • Negative regulation of Toll-like receptor signaling pathway
    • Wang J, Hu Y, Deng WW, Sun B. Negative regulation of Toll-like receptor signaling pathway. Microbes Infect 2009;11:321-7.
    • (2009) Microbes Infect , vol.11 , pp. 321-327
    • Wang, J.1    Hu, Y.2    Deng, W.W.3    Sun, B.4
  • 2
    • 0037629646 scopus 로고    scopus 로고
    • PI3K and negative regulation of TLR signaling
    • Fukao T, Koyasu S. PI3K and negative regulation of TLR signaling. Trends Immunol 2003;24:358-63.
    • (2003) Trends Immunol , vol.24 , pp. 358-363
    • Fukao, T.1    Koyasu, S.2
  • 3
    • 0033516561 scopus 로고    scopus 로고
    • IRAK-M is a novel member of the Pelle/interleukin-1 receptor-associated kinase (IRAK) family
    • Wesche H, Gao X, Li X et al. IRAK-M is a novel member of the Pelle/interleukin-1 receptor-associated kinase (IRAK) family. J Biol Chem 1999;274:19403-10.
    • (1999) J Biol Chem , vol.274 , pp. 19403-10
    • Wesche, H.1    Gao, X.2    Li, X.3
  • 4
    • 3042686382 scopus 로고    scopus 로고
    • The murine IRAK2 gene encodes four alternatively spliced isoforms, two of which are inhibitory
    • Hardy M P, O'Neill LA. The murine IRAK2 gene encodes four alternatively spliced isoforms, two of which are inhibitory. J Biol Chem 2004;279:27699-708.
    • (2004) J Biol Chem , vol.279 , pp. 27699-708
    • Hardy, M.P.1    O'Neill, L.A.2
  • 5
    • 0036079362 scopus 로고    scopus 로고
    • Identification and characterization of murine IRAK-M
    • Rosati O, Martin MU. Identification and characterization of murine IRAK-M. Biochem Biophys Res Commun 2002; 293:1472-7.
    • (2002) Biochem Biophys Res Commun , vol.293 , pp. 1472-1477
    • Rosati, O.1    Martin, M.U.2
  • 6
    • 0037292275 scopus 로고    scopus 로고
    • Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members
    • Janssens S, Beyaert R. Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members. Mol Cell 2003;11:293-302.
    • (2003) Mol Cell , vol.11 , pp. 293-302
    • Janssens, S.1    Beyaert, R.2
  • 7
    • 0037178785 scopus 로고    scopus 로고
    • IRAK-M is a negative regulator of Tolllike receptor signaling
    • Kobayashi K, Hernandez LD, Galan JE et al. IRAK-M is a negative regulator of Tolllike receptor signaling. Cell 2002;110:191-202.
    • (2002) Cell , vol.110 , pp. 191-202
    • Kobayashi, K.1    Hernandez, L.D.2    Galan, J.E.3
  • 8
    • 34250805968 scopus 로고    scopus 로고
    • IRAK-M is involved in the pathogenesis of early-onset persistent asthma
    • Balaci L, Spada MC, Olla N et al. IRAK-M is involved in the pathogenesis of early-onset persistent asthma. Am J Hum Genet 2007; 80:1103-14.
    • (2007) Am J Hum Genet , vol.80 , pp. 1103-1114
    • Balaci, L.1    Spada, M.C.2    Olla, N.3
  • 9
    • 68149169644 scopus 로고    scopus 로고
    • TREM-1 activation alters the dynamics of pulmonary IRAK-M expression in vivo and improves host defense during pneumococcal pneumonia
    • Lagler H, Sharif O, Haslinger I et al. TREM-1 activation alters the dynamics of pulmonary IRAK-M expression in vivo and improves host defense during pneumococcal pneumonia. J Immunol 2009;183:2027-36.
    • (2009) J Immunol , vol.183 , pp. 2027-2036
    • Lagler, H.1    Sharif, O.2    Haslinger, I.3
  • 10
    • 77949313888 scopus 로고    scopus 로고
    • Critical role of IL-1 receptor-associated kinase-M in regulating chemokine-dependent deleterious inflammation in murine influenza pneumonia
    • Seki M, Kohno S, Newstead MW et al. Critical role of IL-1 receptor-associated kinase-M in regulating chemokine-dependent deleterious inflammation in murine influenza pneumonia. J Immunol 2010;184:1410-8.
    • (2010) J Immunol , vol.184 , pp. 1410-1418
    • Seki, M.1    Kohno, S.2    Newstead, M.W.3
  • 11
    • 77953374321 scopus 로고    scopus 로고
    • A role for IL-1 Receptor-associated kinase-M in Prostaglandin E(2)-induced immunosuppression post-bone marrow transplantation
    • Hubbard LL, Ballinger MN, Thomas PE et al. A role for IL-1 Receptor-associated kinase-M in Prostaglandin E(2)-induced immunosuppression post-bone marrow transplantation. J Immunol 2010;184:6299-308.
    • (2010) J Immunol , vol.184 , pp. 6299-6308
    • Hubbard, L.L.1    Ballinger, M.N.2    Thomas, P.E.3
  • 12
    • 37549034962 scopus 로고    scopus 로고
    • B cell intrinsic TLR signals amplify but are not required for humoral immunity
    • Meyer-Bahlburg A, Khim S, Rawlings DJ. B cell intrinsic TLR signals amplify but are not required for humoral immunity. J Exp Med 2007;204:3095-101.
    • (2007) J Exp Med , vol.204 , pp. 3095-3101
    • Meyer-Bahlburg, A.1    Khim, S.2    Rawlings, D.J.3
  • 13
    • 35348822432 scopus 로고    scopus 로고
    • Biliary innate immunity and cholangiopathy
    • Harada K, Nakanuma Y. Biliary innate immunity and cholangiopathy. Hepatol Res 2007;37:S430-7.
    • (2007) Hepatol Res , vol.37
    • Harada, K.1    Nakanuma, Y.2
  • 14
    • 72949102226 scopus 로고    scopus 로고
    • A20 is an early responding negative regulator of Toll-like receptor 5 signalling in intestinal epithelial cells during inflammation
    • Oshima N, Ishihara S, Rumi MA et al. A20 is an early responding negative regulator of Toll-like receptor 5 signalling in intestinal epithelial cells during inflammation. Clin Exp Immunol 2010;159:185-98.
    • (2010) Clin Exp Immunol , vol.159 , pp. 185-198
    • Oshima, N.1    Ishihara, S.2    Rumi, M.A.3
  • 15
    • 34548487143 scopus 로고    scopus 로고
    • Beyond IkappaBs: Alternative regulation of NF-kappaB activity
    • Neumann M, Naumann M. Beyond IkappaBs: alternative regulation of NF-kappaB activity. FASEB J 2007;21:2642-54.
    • (2007) FASEB J , vol.21 , pp. 2642-2654
    • Neumann, M.1    Naumann, M.2
  • 16
    • 33745852665 scopus 로고    scopus 로고
    • Alternative pathways of NF-kappaB activation: A double-edged sword in health and disease
    • Xiao G, Rabson AB, Young W et al. Alternative pathways of NF-kappaB activation: a double-edged sword in health and disease. Cytokine Growth Factor Rev 2006; 17:281-93.
    • (2006) Cytokine Growth Factor Rev , vol.17 , pp. 281-293
    • Xiao, G.1    Rabson, A.B.2    Young, W.3
  • 17
    • 77952395705 scopus 로고    scopus 로고
    • Potent phagocytic activity with impaired antigen presentation identifying lipopolysaccharide-tolerant human monocytes: Demonstration in isolated monocytes from cystic fibrosis patients
    • del Fresno C, Garcia-Rio F, Gomez-Pina V et al. Potent phagocytic activity with impaired antigen presentation identifying lipopolysaccharide-tolerant human monocytes: demonstration in isolated monocytes from cystic fibrosis patients. J Immunol 2009;182:6494-507.
    • (2009) J Immunol , vol.182 , pp. 6494-6507
    • del Fresno, C.1    Garcia-Rio, F.2    Gomez-Pina, V.3
  • 18
    • 77953432630 scopus 로고    scopus 로고
    • The Interleukin-1 Receptor-Associated Kinase M Selectively Inhibits the Alternative, Instead of the Classical NFkappaB Pathway
    • Su J, Zhang T, Tyson J, Li L. The Interleukin-1 Receptor-Associated Kinase M Selectively Inhibits the Alternative, Instead of the Classical NFkappaB Pathway. J Innate Immun 2009;1:164-74.
    • (2009) J Innate Immun , vol.1 , pp. 164-174
    • Su, J.1    Zhang, T.2    Tyson, J.3    Li, L.4
  • 19
    • 28844460239 scopus 로고    scopus 로고
    • The tumor suppressor cylindromatosis (CYLD) acts as a negative regulator for toll-like receptor 2 signaling via negative cross-talk with TRAF6 AND TRAF7
    • Yoshida H, Jono H, Kai H, Li JD. The tumor suppressor cylindromatosis (CYLD) acts as a negative regulator for toll-like receptor 2 signaling via negative cross-talk with TRAF6 AND TRAF7. J Biol Chem 2005;280: 41111-21.
    • (2005) J Biol Chem , vol.280 , pp. 41111-21
    • Yoshida, H.1    Jono, H.2    Kai, H.3    Li, J.D.4
  • 20
    • 34249283423 scopus 로고    scopus 로고
    • Differential regulation and role of interleukin-1 receptor associated kinase-M in innate immunity signaling
    • Su J, Xie Q, Wilson I, Li L. Differential regulation and role of interleukin-1 receptor associated kinase-M in innate immunity signaling. Cell Signal 2007;19:1596-601.
    • (2007) Cell Signal , vol.19 , pp. 1596-1601
    • Su, J.1    Xie, Q.2    Wilson, I.3    Li, L.4
  • 21
    • 9244231842 scopus 로고    scopus 로고
    • CD28 induces immunostimulatory signals in dendritic cells via CD80 and CD86
    • Orabona C, Grohmann U, Belladonna ML et al. CD28 induces immunostimulatory signals in dendritic cells via CD80 and CD86. Nat Immunol 2004;5:1134-42.
    • (2004) Nat Immunol , vol.5 , pp. 1134-1142
    • Orabona, C.1    Grohmann, U.2    Belladonna, M.L.3
  • 22
    • 68949158556 scopus 로고    scopus 로고
    • Differential role for CD80 and CD86 in the regulation of the innate immune response in murine polymicrobial sepsis
    • Nolan A, Kobayashi H, Naveed B et al. Differential role for CD80 and CD86 in the regulation of the innate immune response in murine polymicrobial sepsis. PLoS One 2009;4:e6600.
    • (2009) PLoS One , vol.4
    • Nolan, A.1    Kobayashi, H.2    Naveed, B.3
  • 23
    • 37049018219 scopus 로고    scopus 로고
    • A genome-wide analysis of LPS tolerance in macrophages
    • Mages J, Dietrich H, Lang R. A genome-wide analysis of LPS tolerance in macrophages. Immunobiology 2007;212: 723-37.
    • (2007) Immunobiology , vol.212 , pp. 723-737
    • Mages, J.1    Dietrich, H.2    Lang, R.3
  • 24
    • 10744223303 scopus 로고    scopus 로고
    • Involvement of IRAK-M in peptidoglycan-induced tolerance in macrophages
    • Nakayama K, Okugawa S, Yanagimoto S et al. Involvement of IRAK-M in peptidoglycan-induced tolerance in macrophages. J Biol Chem 2004;279:6629-34.
    • (2004) J Biol Chem , vol.279 , pp. 6629-6634
    • Nakayama, K.1    Okugawa, S.2    Yanagimoto, S.3
  • 25
    • 42149114549 scopus 로고    scopus 로고
    • Lipoteichoic acid isolated from Lactobacillus plantarum inhibits lipopoly -saccharide-induced TNF-alpha production in THP-1 cells and endotoxin shock in mice
    • Kim HG, Kim NR, Gim MG et al. Lipoteichoic acid isolated from Lactobacillus plantarum inhibits lipopoly -saccharide-induced TNF-alpha production in THP-1 cells and endotoxin shock in mice. J Immunol 2008;180:2553-61.
    • (2008) J Immunol , vol.180 , pp. 2553-2561
    • Kim, H.G.1    Kim, N.R.2    Gim, M.G.3
  • 26
    • 61849108166 scopus 로고    scopus 로고
    • Involvement of interleukin-1 receptor-associated kinase (IRAK)-M in toll-like receptor (TLR) 7-mediated tolerance in RAW 264.7 macrophage-like cells
    • Hassan F, Islam S, Tumurkhuu G et al. Involvement of interleukin-1 receptor-associated kinase (IRAK)-M in toll-like receptor (TLR) 7-mediated tolerance in RAW 264.7 macrophage-like cells. Cell Immunol 2009;256:99-103.
    • (2009) Cell Immunol , vol.256 , pp. 99-103
    • Hassan, F.1    Islam, S.2    Tumurkhuu, G.3
  • 27
    • 62449295455 scopus 로고    scopus 로고
    • Prevention of autoimmune disease by induction of tolerance to Toll-like receptor 7
    • Hayashi T, Gray CS, Chan M et al. Prevention of autoimmune disease by induction of tolerance to Toll-like receptor 7. Proc Natl Acad Sci USA 2009;106:2764-9.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 2764-2769
    • Hayashi, T.1    Gray, C.S.2    Chan, M.3
  • 28
    • 47249088365 scopus 로고    scopus 로고
    • CpG DNA prevents liver injury and shock-mediated death by modulating expression of interleukin-1 receptor-associated kinases
    • Kim YI, Park JE, Martinez-Hernandez A, Yi AK. CpG DNA prevents liver injury and shock-mediated death by modulating expression of interleukin-1 receptor-associated kinases. J Biol Chem 2008;283: 15258-70.
    • (2008) J Biol Chem , vol.283 , pp. 15258-70
    • Kim, Y.I.1    Park, J.E.2    Martinez-Hernandez, A.3    Yi, A.K.4
  • 29
    • 33745845536 scopus 로고    scopus 로고
    • Upregulation of TNF-alpha production signaling pathways in monocytes from patients with advanced cirrhosis: Possible role of Akt and IRAK-M
    • Tazi KA, Quioc JJ, Saada V et al. Upregulation of TNF-alpha production signaling pathways in monocytes from patients with advanced cirrhosis: possible role of Akt and IRAK-M. J Hepatol 2006; 45:280-9.
    • (2006) J Hepatol , vol.45 , pp. 280-289
    • Tazi, K.A.1    Quioc, J.J.2    Saada, V.3
  • 30
    • 0242362818 scopus 로고    scopus 로고
    • Rapid up-regulation of IRAK-M expression following a second endotoxin challenge in human monocytes and in monocytes isolated from septic patients
    • Escoll P, del Fresno C, Garcia L et al. Rapid up-regulation of IRAK-M expression following a second endotoxin challenge in human monocytes and in monocytes isolated from septic patients. Biochem Biophys Res Commun 2003;311:465-72.
    • (2003) Biochem Biophys Res Commun , vol.311 , pp. 465-472
    • Escoll, P.1    del Fresno, C.2    Garcia, L.3
  • 31
    • 77950290067 scopus 로고    scopus 로고
    • Adiponectin promotes endotoxin tolerance in macrophages by inducing IRAK-M expression
    • Zacharioudaki V, Androulidaki A, Arranz A et al. Adiponectin promotes endotoxin tolerance in macrophages by inducing IRAK-M expression. J Immunol 2009;182:6444-51.
    • (2009) J Immunol , vol.182 , pp. 6444-6451
    • Zacharioudaki, V.1    Androulidaki, A.2    Arranz, A.3
  • 32
    • 77949493588 scopus 로고    scopus 로고
    • Leptin and adiponectin: From energy and metabolic dysbalance to inflammation and autoimmunity
    • Stofkova A. Leptin and adiponectin: from energy and metabolic dysbalance to inflammation and autoimmunity. Endocr Regul 2009;43:157-68.
    • (2009) Endocr Regul , vol.43 , pp. 157-168
    • Stofkova, A.1
  • 33
    • 17044392279 scopus 로고    scopus 로고
    • The immunomodulating neuropeptide alpha-melanocyte-stimulating hormone (alpha-MSH) suppresses LPS-stimulated TLR4 with IRAK-M in macrophages
    • Taylor AW. The immunomodulating neuropeptide alpha-melanocyte-stimulating hormone (alpha-MSH) suppresses LPS-stimulated TLR4 with IRAK-M in macrophages. J Neuroimmunol 2005;162: 43-50.
    • (2005) J Neuroimmunol , vol.162 , pp. 43-50
    • Taylor, A.W.1
  • 34
    • 44449154904 scopus 로고    scopus 로고
    • Inhibition of TLR activation and up-regulation of IL-1R-associated kinase-M expression by exogenous gangliosides
    • Shen W, Stone K, Jales A et al. Inhibition of TLR activation and up-regulation of IL-1R-associated kinase-M expression by exogenous gangliosides. J Immunol 2008;180: 4425-32.
    • (2008) J Immunol , vol.180 , pp. 4425-4432
    • Shen, W.1    Stone, K.2    Jales, A.3
  • 35
    • 61849139634 scopus 로고    scopus 로고
    • Hyaluronan inhibits expression of ADAMTS4 (aggrecanase-1) in human osteoarthritic chondrocytes
    • Yatabe T, Mochizuki S, Takizawa M et al. Hyaluronan inhibits expression of ADAMTS4 (aggrecanase-1) in human osteoarthritic chondrocytes. Ann Rheum Dis 2009;68:1051-8.
    • (2009) Ann Rheum Dis , vol.68 , pp. 1051-1058
    • Yatabe, T.1    Mochizuki, S.2    Takizawa, M.3
  • 36
    • 20044381107 scopus 로고    scopus 로고
    • Tumor cells deactivate human monocytes by up-regulating IL-1 receptor associated kinase-M expression via CD44 and TLR4
    • del Fresno C, Otero K, Gomez-Garcia L et al. Tumor cells deactivate human monocytes by up-regulating IL-1 receptor associated kinase-M expression via CD44 and TLR4. J Immunol 2005;174:3032-40.
    • (2005) J Immunol , vol.174 , pp. 3032-3040
    • del Fresno, C.1    Otero, K.2    Gomez-Garcia, L.3
  • 37
    • 62349138124 scopus 로고    scopus 로고
    • The COX-2/PGE2 pathway: Key roles in the hallmarks of cancer and adaptation to the tumour microenvironment
    • Greenhough A, Smartt HJ, Moore AE et al. The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment. Carcinogenesis 2009;30:377-86.
    • (2009) Carcinogenesis , vol.30 , pp. 377-386
    • Greenhough, A.1    Smartt, H.J.2    Moore, A.E.3
  • 38
    • 33846101642 scopus 로고    scopus 로고
    • GM-CSF Regulates a PU. 1-Dependent Transcriptional Program Determining the Pulmonary Response to LPS
    • Berclaz PY, Carey B, Fillipi MD et al. GM-CSF Regulates a PU.1-Dependent Transcriptional Program Determining the Pulmonary Response to LPS. Am J Respir Cell Mol Biol 2007;36:114-21.
    • (2007) Am J Respir Cell Mol Biol , vol.36 , pp. 114-121
    • Berclaz, P.Y.1    Carey, B.2    Fillipi, M.D.3
  • 39
    • 34548437576 scopus 로고    scopus 로고
    • Nitric oxide induces SOCS-1 expression in human monocytes in a TNF-alpha-dependent manner
    • Gonzalez-Leon MC, Soares-Schanoski A, del Fresno C et al. Nitric oxide induces SOCS-1 expression in human monocytes in a TNF-alpha-dependent manner. J Endotoxin Res 2006;12:296-306.
    • (2006) J Endotoxin Res , vol.12 , pp. 296-306
    • Gonzalez-Leon, M.C.1    Soares-Schanoski, A.2    del Fresno, C.3
  • 40
    • 3242676995 scopus 로고    scopus 로고
    • Nitric oxide activates the expression of IRAK-M via the release of TNF-alpha in human monocytes
    • del Fresno C, Gomez-Garcia L, Caveda L et al. Nitric oxide activates the expression of IRAK-M via the release of TNF-alpha in human monocytes. Nitric Oxide 2004; 10:213-20.
    • (2004) Nitric Oxide , vol.10 , pp. 213-220
    • del Fresno, C.1    Gomez-Garcia, L.2    Caveda, L.3
  • 41
    • 38449086201 scopus 로고    scopus 로고
    • Induction of IRAK-M is associated with lipopolysaccharide tolerance in a human endotoxemia model
    • van't Veer C, van den Pangaart PS, van Zoelen MA et al. Induction of IRAK-M is associated with lipopolysaccharide tolerance in a human endotoxemia model. J Immunol 2007;179:7110-20.
    • (2007) J Immunol , vol.179 , pp. 7110-7120
    • van't Veer, C.1    van den Pangaart, P.S.2    van Zoelen, M.A.3
  • 42
    • 77954695244 scopus 로고    scopus 로고
    • SMAD4 is required for development of maximal endotoxin tolerance
    • Pan H, Ding E, Hu M. SMAD4 is required for development of maximal endotoxin tolerance. J Immunol 2010;184:5502-9.
    • (2010) J Immunol , vol.184 , pp. 5502-5509
    • Pan, H.1    Ding, E.2    Hu, M.3
  • 43
    • 0037237593 scopus 로고    scopus 로고
    • Mycobacteria target DC-SIGN to suppress dendritic cell function
    • Geijtenbeek TB, Van Vliet SJ, Koppel EA et al. Mycobacteria target DC-SIGN to suppress dendritic cell function. J Exp Med 2003;197:7-17.
    • (2003) J Exp Med , vol.197 , pp. 7-17
    • Geijtenbeek, T.B.1    Van Vliet, S.J.2    Koppel, E.A.3
  • 44
    • 0037458706 scopus 로고    scopus 로고
    • The cell surface receptor DC-SIGN discriminates between Mycobacterium species through selective recognition of the man-nose caps on lipoarabinomannan
    • Maeda N, Nigou J, Herrmann JL et al. The cell surface receptor DC-SIGN discriminates between Mycobacterium species through selective recognition of the man-nose caps on lipoarabinomannan. J Biol Chem 2003;278:5513-6.
    • (2003) J Biol Chem , vol.278 , pp. 5513-5516
    • Maeda, N.1    Nigou, J.2    Herrmann, J.L.3
  • 45
    • 0035876915 scopus 로고    scopus 로고
    • Mannosylated lipoarabinomannans inhibit IL-12 production by human dendritic cells: Evidence for a negative signal delivered through the mannose receptor
    • Nigou J, Zelle-Rieser C, Gilleron M et al. Mannosylated lipoarabinomannans inhibit IL-12 production by human dendritic cells: evidence for a negative signal delivered through the mannose receptor. J Immunol 2001;166:7477-85.
    • (2001) J Immunol , vol.166 , pp. 7477-7485
    • Nigou, J.1    Zelle-Rieser, C.2    Gilleron, M.3
  • 46
    • 30044450421 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis lipoarabinomannan-mediated IRAK-M induction negatively regulates Toll-like receptor-dependent interleukin-12 p40 production in macrophages
    • Pathak SK, Basu S, Bhattacharyya A et al. Mycobacterium tuberculosis lipoarabinomannan-mediated IRAK-M induction negatively regulates Toll-like receptor-dependent interleukin-12 p40 production in macrophages. J Biol Chem 2005;280: 42794-800.
    • (2005) J Biol Chem , vol.280 , pp. 42794-800
    • Pathak, S.K.1    Basu, S.2    Bhattacharyya, A.3
  • 47
    • 12144266586 scopus 로고    scopus 로고
    • Transcriptional profiling reveals complex regulation of the monocyte IL-1 beta system by IL-13
    • Scotton CJ, Martinez FO, Smelt MJ et al. Transcriptional profiling reveals complex regulation of the monocyte IL-1 beta system by IL-13. J Immunol 2005;174:834-45.
    • (2005) J Immunol , vol.174 , pp. 834-845
    • Scotton, C.J.1    Martinez, F.O.2    Smelt, M.J.3
  • 48
    • 70349559403 scopus 로고    scopus 로고
    • Endotoxin tolerance: New mechanisms, molecules and clinical significance
    • Biswas SK, Lopez-Collazo E. Endotoxin tolerance: new mechanisms, molecules and clinical significance. Trends Immunol 2009;30:475-87.
    • (2009) Trends Immunol , vol.30 , pp. 475-487
    • Biswas, S.K.1    Lopez-Collazo, E.2
  • 49
    • 62149130108 scopus 로고    scopus 로고
    • Oral tolerance induced by enterobacteria altered the process of lymphocyte recruitment to intestinal microvessels: Roles of endothelial cell adhesion molecules, TGF-beta and negative regulators of TLR signaling
    • Takebayashi K, Hokari R, Kurihara C et al. Oral tolerance induced by enterobacteria altered the process of lymphocyte recruitment to intestinal microvessels: roles of endothelial cell adhesion molecules, TGF-beta and negative regulators of TLR signaling. Microcirculation 2009;16:251-64.
    • (2009) Microcirculation , vol.16 , pp. 251-264
    • Takebayashi, K.1    Hokari, R.2    Kurihara, C.3
  • 50
    • 34250202513 scopus 로고    scopus 로고
    • Association of interleukin-1 receptor-associated kinase M (IRAK-M) and inflammatory bowel diseases
    • Weersma RK, Oostenbrug LE, Nolte IM et al. Association of interleukin-1 receptor-associated kinase M (IRAK-M) and inflammatory bowel diseases. Scand J Gastroenterol 2007;42:827-33.
    • (2007) Scand J Gastroenterol , vol.42 , pp. 827-833
    • Weersma, R.K.1    Oostenbrug, L.E.2    Nolte, I.M.3
  • 51
    • 65649131286 scopus 로고    scopus 로고
    • IL-6 and TNF-alpha synergistically inhibit allograft acceptance
    • Shen H, Goldstein DR. IL-6 and TNF-alpha synergistically inhibit allograft acceptance. J Am Soc Nephrol 2009;20:1032-40.
    • (2009) J Am Soc Nephrol , vol.20 , pp. 1032-1040
    • Shen, H.1    Goldstein, D.R.2
  • 52
    • 43249118968 scopus 로고    scopus 로고
    • Inhibition of pulmonary antibacterial defense by interferon-gamma during recovery from influenza infection
    • Sun K, Metzger DW. Inhibition of pulmonary antibacterial defense by interferon-gamma during recovery from influenza infection. Nat Med 2008;14:558-64.
    • (2008) Nat Med , vol.14 , pp. 558-564
    • Sun, K.1    Metzger, D.W.2
  • 53
    • 43349105185 scopus 로고    scopus 로고
    • Early and preferential induction of IL-1 receptor-associated kinase-M in THP-1 cells by LPS derived from Porphyromonas gingivalis
    • Domon H, Honda T, Oda T, et al. Early and preferential induction of IL-1 receptor-associated kinase-M in THP-1 cells by LPS derived from Porphyromonas gingivalis. J Leukoc Biol 2008;83:672-9.
    • (2008) J Leukoc Biol , vol.83 , pp. 672-679
    • Domon, H.1    Honda, T.2    Oda, T.3
  • 54
    • 67650401419 scopus 로고    scopus 로고
    • Immunosuppression associated with interleukin-1R-associated-kinase-M upregulation predicts mortality in Gram-negative sepsis (melioidosis)
    • Wiersinga WJ, van't Veer C, van den Pangaart PS et al. Immunosuppression associated with interleukin-1R-associated-kinase-M upregulation predicts mortality in Gram-negative sepsis (melioidosis). Crit Care Med 2009;37:569-76.
    • (2009) Crit Care Med , vol.37 , pp. 569-576
    • Wiersinga, W.J.1    van't Veer, C.2    van den Pangaart, P.S.3
  • 55
    • 33748317968 scopus 로고    scopus 로고
    • Sepsis-induced suppression of lung innate immunity is mediated by IRAK-M
    • Deng JC, Cheng G, Newstead MW et al. Sepsis-induced suppression of lung innate immunity is mediated by IRAK-M. J Clin Invest 2006;116:2532-42.
    • (2006) J Clin Invest , vol.116 , pp. 2532-2542
    • Deng, J.C.1    Cheng, G.2    Newstead, M.W.3
  • 56
    • 20044381107 scopus 로고    scopus 로고
    • Tumor cells deactivate human monocytes by up-regulating IL-1 receptor associated kinase-M expression via CD44 and TLR4
    • del Fresno C, Otero K, Gomez-Garcia L et al. Tumor cells deactivate human monocytes by up-regulating IL-1 receptor associated kinase-M expression via CD44 and TLR4. J Immunol 2005;174:3032-40.
    • (2005) J Immunol , vol.174 , pp. 3032-3040
    • del Fresno, C.1    Otero, K.2    Gomez-Garcia, L.3
  • 57
    • 34248587897 scopus 로고    scopus 로고
    • Loss of the innate immunity negative regulator IRAK-M leads to enhanced host immune defense against tumor growth
    • Xie Q, Gan L, Wang J et al. Loss of the innate immunity negative regulator IRAK-M leads to enhanced host immune defense against tumor growth. Mol Immunol 2007;44:3453-61.
    • (2007) Mol Immunol , vol.44 , pp. 3453-3461
    • Xie, Q.1    Gan, L.2    Wang, J.3
  • 58
    • 18744407631 scopus 로고    scopus 로고
    • Immune restoration following hematopoietic stem cell transplantation: An evolving target
    • Auletta JJ, Lazarus HM. Immune restoration following hematopoietic stem cell transplantation: an evolving target. Bone Marrow Transplant 2005;35:835-57.
    • (2005) Bone Marrow Transplant , vol.35 , pp. 835-857
    • Auletta, J.J.1    Lazarus, H.M.2
  • 59
    • 3242886732 scopus 로고    scopus 로고
    • Pulmonary complications of solid organ and hematopoietic stem cell transplantation
    • Kotloff R, Ahya V, Crawford SW. Pulmonary complications of solid organ and hematopoietic stem cell transplantation. Am J Respir Crit Care Med 2004;170:22-48.
    • (2004) Am J Respir Crit Care Med , vol.170 , pp. 22-48
    • Kotloff, R.1    Ahya, V.2    Crawford, S.W.3
  • 60
    • 33749526328 scopus 로고    scopus 로고
    • Critical Role of Prostaglandin E2 Overproduction in Impaired Pulmonary Host Response Following Bone Marrow Transplantation
    • Ballinger MN, Aronoff DM, McMillan TR, et al. Critical Role of Prostaglandin E2 Overproduction in Impaired Pulmonary Host Response Following Bone Marrow Transplantation. J Immunol 2006;177: 5499-508.
    • (2006) J Immunol , vol.177 , pp. 5499-5508
    • Ballinger, M.N.1    Aronoff, D.M.2    McMillan, T.R.3
  • 61
    • 0141958113 scopus 로고    scopus 로고
    • Defective phagocytosis and clearance of Pseudomonas aeruginosa in the Lung Following Bone Marrow Transplantation
    • Ojielo C, Cooke KR, Mancuso P et al. Defective phagocytosis and clearance of Pseudomonas aeruginosa in the Lung Following Bone Marrow Transplantation. J Immunol 2003;171:4416-24.
    • (2003) J Immunol , vol.171 , pp. 4416-4424
    • Ojielo, C.1    Cooke, K.R.2    Mancuso, P.3
  • 62
    • 2442643942 scopus 로고    scopus 로고
    • Triad3A, an E3 ubiquitin-protein ligase regulating Tolllike receptors
    • Chuang TH, Ulevitch RJ. Triad3A, an E3 ubiquitin-protein ligase regulating Tolllike receptors. Nat Immunol 2004;5:495-502.
    • (2004) Nat Immunol , vol.5 , pp. 495-502
    • Chuang, T.H.1    Ulevitch, R.J.2
  • 63
    • 31344467156 scopus 로고    scopus 로고
    • Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation
    • Mansell A, Smith R, Doyle SL et al. Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation. Nat Immunol 2006;7:148-55.
    • (2006) Nat Immunol , vol.7 , pp. 148-155
    • Mansell, A.1    Smith, R.2    Doyle, S.L.3
  • 64
    • 33744499683 scopus 로고    scopus 로고
    • Negative regulation of interferon-regulatory factor 3-dependent innate antiviral response by the prolyl isomerase Pin1
    • Saitoh T, Tun-Kyi A, Ryo A et al. Negative regulation of interferon-regulatory factor 3-dependent innate antiviral response by the prolyl isomerase Pin1. Nat Immunol 2006;7:598-605.
    • (2006) Nat Immunol , vol.7 , pp. 598-605
    • Saitoh, T.1    Tun-Kyi, A.2    Ryo, A.3
  • 65
    • 5444223519 scopus 로고    scopus 로고
    • The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses
    • Boone DL, Turer EE, Lee EG et al. The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses. Nat Immunol 2004;5:1052-60.
    • (2004) Nat Immunol , vol.5 , pp. 1052-1060
    • Boone, D.L.1    Turer, E.E.2    Lee, E.G.3
  • 66
    • 36448943427 scopus 로고    scopus 로고
    • DUBA: A deubiquitinase that regulates type I interferon production
    • Kayagaki N, Phung Q, Chan S et al. DUBA: a deubiquitinase that regulates type I interferon production. Science 2007;318: 1628-32.
    • (2007) Science , vol.318 , pp. 1628-1632
    • Kayagaki, N.1    Phung, Q.2    Chan, S.3
  • 67
    • 33748871187 scopus 로고    scopus 로고
    • The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling
    • Carty M, Goodbody R, Schroder M et al. The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling. Nat Immunol 2006;7:1074-81.
    • (2006) Nat Immunol , vol.7 , pp. 1074-1081
    • Carty, M.1    Goodbody, R.2    Schroder, M.3
  • 68
    • 20644450101 scopus 로고    scopus 로고
    • Negative regulation of Toll-like receptor 4 signaling by the Toll-like receptor homolog RP105
    • Divanovic S, Trompette A, Atabani SF et al. Negative regulation of Toll-like receptor 4 signaling by the Toll-like receptor homolog RP105. Nat Immunol 2005;6:571-8.
    • (2005) Nat Immunol , vol.6 , pp. 571-578
    • Divanovic, S.1    Trompette, A.2    Atabani, S.F.3
  • 69
    • 0036006290 scopus 로고    scopus 로고
    • Regulation of interleukin-1- and lipopolysaccharide-induced NF-kappaB activation by alternative splicing of MyD88
    • Janssens S, Burns K, Tschopp J, Beyaert R. Regulation of interleukin-1- and lipopolysaccharide-induced NF-kappaB activation by alternative splicing of MyD88. Curr Biol 2002;12:467-71.
    • (2002) Curr Biol , vol.12 , pp. 467-471
    • Janssens, S.1    Burns, K.2    Tschopp, J.3    Beyaert, R.4
  • 70
    • 10344260656 scopus 로고    scopus 로고
    • TRAIL-R as a negative regulator of innate immune cell responses
    • Diehl GE, Yue HH, Hsieh K et al. TRAIL-R as a negative regulator of innate immune cell responses. Immunity 2004;21:877-89.
    • (2004) Immunity , vol.21 , pp. 877-889
    • Diehl, G.E.1    Yue, H.H.2    Hsieh, K.3
  • 71
    • 33646547951 scopus 로고    scopus 로고
    • Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4
    • Gilchrist M, Thorsson V, Li B et al. Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4. Nature 2006;441:173-8.
    • (2006) Nature , vol.441 , pp. 173-178
    • Gilchrist, M.1    Thorsson, V.2    Li, B.3
  • 72
    • 0034672088 scopus 로고    scopus 로고
    • Cutting edge: Naturally occurring soluble form of mouse Toll-like receptor 4 inhibits lipopolysaccharide signaling
    • Iwami KI, Matsuguchi T, Masuda A et al. Cutting edge: naturally occurring soluble form of mouse Toll-like receptor 4 inhibits lipopolysaccharide signaling. J Immunol 2000;165:6682-6.
    • (2000) J Immunol , vol.165 , pp. 6682-6686
    • Iwami, K.I.1    Matsuguchi, T.2    Masuda, A.3
  • 73
    • 42449121356 scopus 로고    scopus 로고
    • Phosphatase SHP-1 promotes TLR- and RIG-I-activated production of type I interferon by inhibiting the kinase IRAK1
    • An H, Hou J, Zhou J et al. Phosphatase SHP-1 promotes TLR- and RIG-I-activated production of type I interferon by inhibiting the kinase IRAK1. Nat Immunol 2008; 9:542-50.
    • (2008) Nat Immunol , vol.9 , pp. 542-550
    • An, H.1    Hou, J.2    Zhou, J.3
  • 74
    • 33845438110 scopus 로고    scopus 로고
    • SHP-2 phosphatase negatively regulates the TRIF adaptor protein-dependent type I interferon and proinflammatory cytokine production
    • An H, Zhao W, Hou J et al. SHP-2 phosphatase negatively regulates the TRIF adaptor protein-dependent type I interferon and proinflammatory cytokine production. Immunity 2006;25:919-28.
    • (2006) Immunity , vol.25 , pp. 919-928
    • An, H.1    Zhao, W.2    Hou, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.