Isatin 1,2,3-triazoles as potent inhibitors against caspase-3

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 6, 2011, Pages 1626-1629

  Jiang, Yang ^a   Hansen, Trond Vidar ^a  

^a UNIVERSITY OF OSLO   (Norway)

Author keywords

1,2,3 Triazole; Caspase 3; Inhibitors; Isatin

Indexed keywords

1 [(1 BENZYL 1H 1,2,3 TRIAZOL 5 YL)METHYL] 5 [[2 (METHOXYMETHYL)PYRROLIDIN 1 YL]SULFONYL]INDOLINE 2,3 DIONE; 1 [[1 (2,3 DIHYDRO BENZO[B][1,4]DIOXIN 6 YL) 1H 1,2,3 TRIAZOL 4 YL]METHYL] 5 [[2 (METHOXYMETHYL)PYRROLIDIN 1 YL]SULFONYL]INDOLINE 2,3 DIONE; CASPASE 3; CASPASE 3 INHIBITOR; ISATIN 1,2,3 TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CHEMICAL MODIFICATION; CONTROLLED STUDY; CYCLOADDITION; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; IC 50; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION;

CASPASE 3; ENZYME INHIBITORS; ISATIN; TRIAZOLES;

EID: 79952362107     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.01.110     Document Type: Article

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