Design, synthesis, and preliminary biological evaluation of a novel triazole analogue of ceramide

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 16, 2007, Pages 4584-4587

  Kim, Sanghee ^a   Cho, Minjae ^a   Lee, Taeho ^a   Lee, Sukjin ^a   Min, Hye Young ^b   Lee, Sang Kook ^b  

^a Seoul National University   (South Korea)

^b Ewha Womans University   (South Korea)

Author keywords

1,2,3 Triazole; Apoptosis; Bioisosteric substitution; Ceramide; Click chemistry

Indexed keywords

CERAMIDE; TRIAZOLE;

ARTICLE; CYTOTOXICITY; DRUG ACTIVITY; DRUG DESIGN; DRUG MECHANISM; DRUG POTENCY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HYDROLYSIS;

APOPTOSIS; CELL LINE; CERAMIDES; DRUG DESIGN; HUMANS; TRIAZOLES;

EID: 34447515534     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.05.086     Document Type: Article

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