1,3-Dioxo-4-methyl-2,3-dihydro-1H-pyrrolo[3,4-c]quinolines as potent caspase-3 inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 7, 2005, Pages 1841-1845

  Kravchenko, Dmitri V ^a   Kysil, Vladimir V ^b   Ilyn, Alexey P ^b   Tkachenko, Sergey E ^a,b   Maliarchouk, Sergey ^a,b   Okun, Ilya M ^a,b   Ivachtchenko, Alexandre V ^b  

^a Chemical Diversity Research Institute   (Russian Federation)

^b CHEMDIV INC   (United States)

Author keywords

1H pyrrolo 3,4 c quinoline; Caspase 3; Inhibitor

Indexed keywords

CASPASE 3 INHIBITOR; QUINOLINE DERIVATIVE; SULFAMIDE DERIVATIVE;

ARTICLE; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; IC 50; STRUCTURE ACTIVITY RELATION;

EID: 15044358314     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.02.027     Document Type: Article

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