-
1
-
-
34347342722
-
Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors
-
Agarwal N, Pacher P, Tegeder I et al. (2007) Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors. Nat Neurosci 10:870-879
-
(2007)
Nat Neurosci
, vol.10
, pp. 870-879
-
-
Agarwal, N.1
Pacher, P.2
Tegeder, I.3
-
2
-
-
42349086864
-
Endocannabinoids and the regulation of bone metabolism
-
Bab I, Ofek O, Tam J et al. (2008) Endocannabinoids and the regulation of bone metabolism. J Neuroendocrinol 20(Suppl 1):69-74
-
(2008)
J Neuroendocrinol
, vol.20
, Issue.SUPPL.1
, pp. 69-74
-
-
Bab, I.1
Ofek, O.2
Tam, J.3
-
3
-
-
0034685843
-
Role of the endogenous cannabinoid system in the formalin test of persistent pain in the rat
-
Beaulieu P, Bisogno T, Punwar S et al. (2000) Role of the endogenous cannabinoid system in the formalin test of persistent pain in the rat. Eur J Pharmacol 396:85-92
-
(2000)
Eur J Pharmacol
, vol.396
, pp. 85-92
-
-
Beaulieu, P.1
Bisogno, T.2
Punwar, S.3
-
4
-
-
33645106816
-
CB2 receptor-mediated antihyperalgesia: Possible direct involvement of neural mechanisms
-
Beltramo M, Bernardini N, Bertorelli R et al. (2006) CB2 receptor-mediated antihyperalgesia: possible direct involvement of neural mechanisms. Eur J Neurosci 23:1530-1538
-
(2006)
Eur J Neurosci
, vol.23
, pp. 1530-1538
-
-
Beltramo, M.1
Bernardini, N.2
Bertorelli, R.3
-
5
-
-
29844435136
-
Preliminary assessment of the efficacy, tolerability and safety of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis
-
Blake DR, Robson P, Ho M et al. (2006) Preliminary assessment of the efficacy, tolerability and safety of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis. Rheumatology (Oxford) 45:50-52
-
(2006)
Rheumatology (Oxford)
, vol.45
, pp. 50-52
-
-
Blake, D.R.1
Robson, P.2
Ho, M.3
-
6
-
-
35748973885
-
Novel cannabinoid receptors
-
Brown AJ (2007) Novel cannabinoid receptors. Br J Pharmacol 152:567-575
-
(2007)
Br J Pharmacol
, vol.152
, pp. 567-575
-
-
Brown, A.J.1
-
7
-
-
33646431125
-
Inhibition of fatty acid amide hydrolase produces analgesia by multiple mechanisms
-
Chang L, Luo L, Palmer JA et al. (2006) Inhibition of fatty acid amide hydrolase produces analgesia by multiple mechanisms. Br J Pharmacol 148:102-113
-
(2006)
Br J Pharmacol
, vol.148
, pp. 102-113
-
-
Chang, L.1
Luo, L.2
Palmer, J.A.3
-
8
-
-
0032588146
-
The cannabinoid CB1 receptor antagonist, SR141716A, selectively facilitates nociceptive responses of dorsal horn neurones in the rat
-
Chapman V (1999) The cannabinoid CB1 receptor antagonist, SR141716A, selectively facilitates nociceptive responses of dorsal horn neurones in the rat. Br J Pharmacol 127:1765-1767
-
(1999)
Br J Pharmacol
, vol.127
, pp. 1765-1767
-
-
Chapman, V.1
-
9
-
-
38349117232
-
Differential effects of cannabinoid receptor agonists on regional brain activity using pharmacological MRI
-
Chin CL, Tovcimak AE, Hradil VP et al. (2008) Differential effects of cannabinoid receptor agonists on regional brain activity using pharmacological MRI. Br J Pharmacol 153:367-379
-
(2008)
Br J Pharmacol
, vol.153
, pp. 367-379
-
-
Chin, C.L.1
Tovcimak, A.E.2
Hradil, V.P.3
-
10
-
-
0036221971
-
CB1 and CB2 cannabinoid receptors are implicated in inflammatory pain
-
Clayton N, Marshall FH, Bountra C et al. (2002) CB1 and CB2 cannabinoid receptors are implicated in inflammatory pain. Pain 96:253-260
-
(2002)
Pain
, vol.96
, pp. 253-260
-
-
Clayton, N.1
Marshall, F.H.2
Bountra, C.3
-
11
-
-
2942579681
-
The antinociceptive effect of Delta9-tetrahydrocannabinol in the arthritic rat
-
Cox ML, Welch SP (2004) The antinociceptive effect of Delta9-tetrahydrocannabinol in the arthritic rat. Eur J Pharmacol 493:65-74
-
(2004)
Eur J Pharmacol
, vol.493
, pp. 65-74
-
-
Cox, M.L.1
Welch, S.P.2
-
12
-
-
34547837599
-
The antinociceptive effect of Delta9-tetrahydrocannabinol in the arthritic rat involves the CB(2) cannabinoid receptor
-
Cox ML, Haller VL, Welch SP (2007a) The antinociceptive effect of Delta9-tetrahydrocannabinol in the arthritic rat involves the CB(2) cannabinoid receptor. Eur J Pharmacol 570:50-56
-
(2007)
Eur J Pharmacol
, vol.570
, pp. 50-56
-
-
Cox, M.L.1
Haller, V.L.2
Welch, S.P.3
-
13
-
-
34249108566
-
Synergy between delta9-tetrahydrocannabinol and morphine in the arthritic rat
-
Cox ML, Haller VL, Welch SP (2007b) Synergy between delta9-tetrahydrocannabinol and morphine in the arthritic rat. Eur J Pharmacol 567:125-130
-
(2007)
Eur J Pharmacol
, vol.567
, pp. 125-130
-
-
Cox, M.L.1
Haller, V.L.2
Welch, S.P.3
-
14
-
-
0029904838
-
Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides
-
Cravatt BF, Giang DK, Mayfield SP et al. (1996) Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides. Nature 384:83-87
-
(1996)
Nature
, vol.384
, pp. 83-87
-
-
Cravatt, B.F.1
Giang, D.K.2
Mayfield, S.P.3
-
15
-
-
0035979244
-
Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase
-
Cravatt BF, Demarest K, Patricelli MP et al. (2001) Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase. Proc Natl Acad Sci USA 98:9371-9376
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 9371-9376
-
-
Cravatt, B.F.1
Demarest, K.2
Patricelli, M.P.3
-
16
-
-
0027180394
-
Enzymatic synthesis and degradation of anandamide, a cannabinoid receptor agonist
-
Deutsch DG, Chin SA (1993) Enzymatic synthesis and degradation of anandamide, a cannabinoid receptor agonist. Biochem Pharmacol 46:791-796
-
(1993)
Biochem Pharmacol
, vol.46
, pp. 791-796
-
-
Deutsch, D.G.1
Chin, S.A.2
-
17
-
-
0027078685
-
Isolation and structure of a brain constituent that binds to the cannabinoid receptor
-
Devane WA, Hanus L, Breuer A et al. (1992) Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science 258:1946-1949
-
(1992)
Science
, vol.258
, pp. 1946-1949
-
-
Devane, W.A.1
Hanus, L.2
Breuer, A.3
-
18
-
-
0036678094
-
Brain monoglyceride lipase participating in endocannabinoid inactivation
-
Dinh TP, Carpenter D, Leslie FM et al. (2002) Brain monoglyceride lipase participating in endocannabinoid inactivation. Proc Natl Acad Sci USA 99:10819-10824
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 10819-10824
-
-
Dinh, T.P.1
Carpenter, D.2
Leslie, F.M.3
-
19
-
-
0034717944
-
Localisation of cannabinoid receptors in the rat brain using antibodies to the intracellular C-terminal tail of CB
-
Egertova M, Elphick MR (2000) Localisation of cannabinoid receptors in the rat brain using antibodies to the intracellular C-terminal tail of CB. J Comp Neurol 422:159-171
-
(2000)
J Comp Neurol
, vol.422
, pp. 159-171
-
-
Egertova, M.1
Elphick, M.R.2
-
20
-
-
8144229133
-
Cannabinoid CB2 receptor activation inhibits mechanically evoked responses of wide dynamic range dorsal horn neurons in naive rats and in rat models of inflammatory and neuropathic pain
-
Elmes SJ, JhaveriMD, Smart D et al. (2004) Cannabinoid CB2 receptor activation inhibits mechanically evoked responses of wide dynamic range dorsal horn neurons in naive rats and in rat models of inflammatory and neuropathic pain. Eur J Neurosci 20:2311-2320
-
(2004)
Eur J Neurosci
, vol.20
, pp. 2311-2320
-
-
Elmes, S.J.1
Jhaveri, M.D.2
Smart, D.3
-
21
-
-
28644451441
-
Activation of CB1 and CB2 receptors attenuates the induction and maintenance of inflammatory pain in the rat
-
Elmes SJ, Winyard LA, Medhurst SJ et al. (2005) Activation of CB1 and CB2 receptors attenuates the induction and maintenance of inflammatory pain in the rat. Pain 118:327-335
-
(2005)
Pain
, vol.118
, pp. 327-335
-
-
Elmes, S.J.1
Winyard, L.A.2
Medhurst, S.J.3
-
22
-
-
15744385109
-
Characterization of the fatty acid amide hydrolase inhibitor cyclohexyl carbamic acid 30-carbamoyl-biphenyl-3-yl ester (URB597): Effects on anandamide and oleoylethanolamide deactivation
-
Fegley D, Gaetani S, Duranti A et al. (2005) Characterization of the fatty acid amide hydrolase inhibitor cyclohexyl carbamic acid 30-carbamoyl-biphenyl-3-yl ester (URB597): effects on anandamide and oleoylethanolamide deactivation. J Pharmacol Exp Ther 313:352-358
-
(2005)
J Pharmacol Exp Ther
, vol.313
, pp. 352-358
-
-
Fegley, D.1
Gaetani, S.2
Duranti, A.3
-
23
-
-
0043073239
-
Effects of direct periaqueductal grey administration of a cannabinoid receptor agonist on nociceptive and aversive responses in rats
-
Finn DP, Jhaveri MD, Beckett SR et al. (2003) Effects of direct periaqueductal grey administration of a cannabinoid receptor agonist on nociceptive and aversive responses in rats. Neuropharmacology 45:594-604
-
(2003)
Neuropharmacology
, vol.45
, pp. 594-604
-
-
Finn, D.P.1
Jhaveri, M.D.2
Beckett, S.R.3
-
24
-
-
35649011495
-
The contribution of cyclooxygenase-2 to endocannabinoid metabolism and action
-
Fowler CJ (2007) The contribution of cyclooxygenase-2 to endocannabinoid metabolism and action. Br J Pharmacol 152:594-601
-
(2007)
Br J Pharmacol
, vol.152
, pp. 594-601
-
-
Fowler, C.J.1
-
25
-
-
0029094470
-
Expression of central and peripheral cannabinoid receptors in human immune tissues and leukocyte subpopulations
-
Galiegue S, Mary S, Marchand J et al. (1995) Expression of central and peripheral cannabinoid receptors in human immune tissues and leukocyte subpopulations. Eur J Biochem 232:54-61
-
(1995)
Eur J Biochem
, vol.232
, pp. 54-61
-
-
Galiegue, S.1
Mary, S.2
Marchand, J.3
-
26
-
-
0035112856
-
Anandamide activates peripheral nociceptors in normal and arthritic rat knee joints
-
Gauldie SD, McQueen DS, Pertwee R et al. (2001) Anandamide activates peripheral nociceptors in normal and arthritic rat knee joints. Br J Pharmacol 132:617-621
-
(2001)
Br J Pharmacol
, vol.132
, pp. 617-621
-
-
Gauldie, S.D.1
McQueen, D.S.2
Pertwee, R.3
-
27
-
-
32844465920
-
Cannabinoid CB2 receptors: Immunohistochemical localization in rat brain
-
Gong JP, Onaivi ES, Ishiguro H et al. (2006) Cannabinoid CB2 receptors: immunohistochemical localization in rat brain. Brain Res 1071:10-23
-
(2006)
Brain Res
, vol.1071
, pp. 10-23
-
-
Gong, J.P.1
Onaivi, E.S.2
Ishiguro, H.3
-
28
-
-
38349119715
-
Cannabinoid CB2 receptors: A therapeutic target for the treatment of inflammatory and neuropathic pain
-
Guindon J, Hohmann AG (2008) Cannabinoid CB2 receptors: a therapeutic target for the treatment of inflammatory and neuropathic pain. Br J Pharmacol 153:319-334
-
(2008)
Br J Pharmacol
, vol.153
, pp. 319-334
-
-
Guindon, J.1
Hohmann, A.G.2
-
29
-
-
33947302244
-
The antinociceptive effects of intraplantar injections of 2-arachidonoyl glycerol are mediated by cannabinoid CB2 receptors
-
Guindon J, Desroches J, Beaulieu P (2007) The antinociceptive effects of intraplantar injections of 2-arachidonoyl glycerol are mediated by cannabinoid CB2 receptors. Br J Pharmacol 150:693-701
-
(2007)
Br J Pharmacol
, vol.150
, pp. 693-701
-
-
Guindon, J.1
Desroches, J.2
Beaulieu, P.3
-
30
-
-
0035957425
-
2-Arachidonyl glyceryl ether, an endogenous agonist of the cannabinoid CB1 receptor
-
Hanus L, Abu-Lafi S, Fride E et al. (2001) 2-Arachidonyl glyceryl ether, an endogenous agonist of the cannabinoid CB1 receptor. Proc Natl Acad Sci USA 98:3662-3665
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 3662-3665
-
-
Hanus, L.1
Abu-Lafi, S.2
Fride, E.3
-
31
-
-
0034699017
-
Spinal anandamide inhibits nociceptive transmission via cannabinoid receptor activation in vivo
-
Harris J, Drew LJ, Chapman V (2000) Spinal anandamide inhibits nociceptive transmission via cannabinoid receptor activation in vivo. NeuroReport 11:2817-2819
-
(2000)
NeuroReport
, vol.11
, pp. 2817-2819
-
-
Harris, J.1
Drew, L.J.2
Chapman, V.3
-
32
-
-
0025760879
-
Neuronal localization of cannabinoid receptors and second messengers in mutant mouse cerebellum
-
Herkenham M, Groen BG, Lynn AB et al. (1991) Neuronal localization of cannabinoid receptors and second messengers in mutant mouse cerebellum. Brain Res 552:301-310
-
(1991)
Brain Res
, vol.552
, pp. 301-310
-
-
Herkenham, M.1
Groen, B.G.2
Lynn, A.B.3
-
33
-
-
0037207078
-
Spinal and peripheral mechanisms of cannabinoid antinociception: Behavioral, neurophysiological and neuroanatomical perspectives
-
Hohmann AG (2002) Spinal and peripheral mechanisms of cannabinoid antinociception: behavioral, neurophysiological and neuroanatomical perspectives. Chem Phys Lipids 121:173-190
-
(2002)
Chem Phys Lipids
, vol.121
, pp. 173-190
-
-
Hohmann, A.G.1
-
34
-
-
0032484245
-
Cannabinoid modulation of wide dynamic range neurons in the lumbar dorsal horn of the rat by spinally administered WIN55, 212-2
-
Hohmann AG, Tsou K, Walker JM (1998) Cannabinoid modulation of wide dynamic range neurons in the lumbar dorsal horn of the rat by spinally administered WIN55, 212-2. Neurosci Lett 257:119-122
-
(1998)
Neurosci Lett
, vol.257
, pp. 119-122
-
-
Hohmann, A.G.1
Tsou, K.2
Walker, J.M.3
-
35
-
-
27144431754
-
Inhibitors of fatty acid amide hydrolase reduce carrageenaninduced hind paw inflammation in pentobarbital-treated mice: Comparison with indomethacin and possible involvement of cannabinoid receptors
-
Holt S, Comelli F, Costa B et al. (2005) Inhibitors of fatty acid amide hydrolase reduce carrageenaninduced hind paw inflammation in pentobarbital-treated mice: comparison with indomethacin and possible involvement of cannabinoid receptors. Br J Pharmacol 146:467-476
-
(2005)
Br J Pharmacol
, vol.146
, pp. 467-476
-
-
Holt, S.1
Comelli, F.2
Costa, B.3
-
36
-
-
0037062411
-
An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors
-
Huang SM, Bisogno T, Trevisani M et al. (2002) An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors. Proc Natl Acad Sci USA 99:8400-8405
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 8400-8405
-
-
Huang, S.M.1
Bisogno, T.2
Trevisani, M.3
-
37
-
-
20044368975
-
CB2 cannabinoid receptor activation produces antinociception by stimulating peripheral release of endogenous opioids
-
Ibrahim MM, Porreca F, Lai J et al. (2005) CB2 cannabinoid receptor activation produces antinociception by stimulating peripheral release of endogenous opioids. Proc Natl Acad Sci USA 102:3093-3098
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 3093-3098
-
-
Ibrahim, M.M.1
Porreca, F.2
Lai, J.3
-
38
-
-
33646062552
-
CB2 cannabinoid receptor mediation of antinociception
-
Ibrahim MM, Rude ML, Stagg NJ et al. (2006) CB2 cannabinoid receptor mediation of antinociception. Pain 122:36-42
-
(2006)
Pain
, vol.122
, pp. 36-42
-
-
Ibrahim, M.M.1
Rude, M.L.2
Stagg, N.J.3
-
39
-
-
0036462447
-
Cannabinoids: A real prospect for pain relief?
-
Iversen L, Chapman V (2002) Cannabinoids: a real prospect for pain relief? Curr Opin Pharmacol 2:50-55
-
(2002)
Curr Opin Pharmacol
, vol.2
, pp. 50-55
-
-
Iversen, L.1
Chapman, V.2
-
40
-
-
32244432341
-
Actions of the FAAH inhibitor URB597 in neuropathic and inflammatory chronic pain models
-
Jayamanne A, Greenwood R, Mitchell VA et al. (2006) Actions of the FAAH inhibitor URB597 in neuropathic and inflammatory chronic pain models. Br J Pharmacol 147:281-288
-
(2006)
Br J Pharmacol
, vol.147
, pp. 281-288
-
-
Jayamanne, A.1
Greenwood, R.2
Mitchell, V.A.3
-
41
-
-
33845799619
-
Analgesic effects of fatty acid amide hydrolase inhibition in a rat model of neuropathic pain
-
Jhaveri MD, Richardson D, Kendall DA et al. (2006) Analgesic effects of fatty acid amide hydrolase inhibition in a rat model of neuropathic pain. J Neurosci 26:13318-13327
-
(2006)
J Neurosci
, vol.26
, pp. 13318-13327
-
-
Jhaveri, M.D.1
Richardson, D.2
Kendall, D.A.3
-
42
-
-
35648999552
-
Endocannabinoid metabolism and uptake: Novel targets for neuropathic and inflammatory pain
-
Jhaveri MD, Richardson D, Chapman V (2007a) Endocannabinoid metabolism and uptake: novel targets for neuropathic and inflammatory pain. Br J Pharmacol 152:624-632
-
(2007)
Br J Pharmacol
, vol.152
, pp. 624-632
-
-
Jhaveri, M.D.1
Richardson, D.2
Chapman, V.3
-
43
-
-
38449119121
-
Cannabinoid CB(2) receptor-mediated antinociception in models of acute and chronic pain
-
Jhaveri MD, Sagar DR, Elmes SJ et al. (2007b) Cannabinoid CB(2) receptor-mediated antinociception in models of acute and chronic pain. Mol Neurobiol 36:26-35
-
(2007)
Mol Neurobiol
, vol.36
, pp. 26-35
-
-
Jhaveri, M.D.1
Sagar, D.R.2
Elmes, S.J.3
-
44
-
-
41549099628
-
Evidence for a novel functional role of cannabinoid CB receptors in the thalamus of neuropathic rats
-
Jhaveri MD, Elmes SJ, Richardson D et al. (2008a) Evidence for a novel functional role of cannabinoid CB receptors in the thalamus of neuropathic rats. Eur J Neurosci 27:1722-1730
-
(2008)
Eur J Neurosci
, vol.27
, pp. 1722-1730
-
-
Jhaveri, M.D.1
Elmes, S.J.2
Richardson, D.3
-
45
-
-
45849106100
-
Inhibition of fatty acid amide hydrolase and cyclooxygenase-2 increases levels of endocannabinoid related molecules and produces analgesia via peroxisome proliferator-activated receptor-alpha in a model of inflammatory pain
-
Jhaveri MD, Richardson D, Robinson I et al. (2008b) Inhibition of fatty acid amide hydrolase and cyclooxygenase-2 increases levels of endocannabinoid related molecules and produces analgesia via peroxisome proliferator-activated receptor-alpha in a model of inflammatory pain. Neuropharmacology 55:85-93
-
(2008)
Neuropharmacology
, vol.55
, pp. 85-93
-
-
Jhaveri, M.D.1
Richardson, D.2
Robinson, I.3
-
46
-
-
35648959293
-
The novel endocannabinoid receptor GPR55 is activated by atypical cannabinoids but does not mediate their vasodilator effects
-
Johns DG, Behm DJ, Walker DJ et al. (2007) The novel endocannabinoid receptor GPR55 is activated by atypical cannabinoids but does not mediate their vasodilator effects. Br J Pharmacol 152:825-831
-
(2007)
Br J Pharmacol
, vol.152
, pp. 825-831
-
-
Johns, D.G.1
Behm, D.J.2
Walker, D.J.3
-
47
-
-
27944510259
-
Cannabinoid receptor type 2 gene is associated with human osteoporosis
-
Karsak M, Cohen-Solal M, Freudenberg J et al. (2005) Cannabinoid receptor type 2 gene is associated with human osteoporosis. Hum Mol Genet 14:3389-3396
-
(2005)
Hum Mol Genet
, vol.14
, pp. 3389-3396
-
-
Karsak, M.1
Cohen-Solal, M.2
Freudenberg, J.3
-
48
-
-
0037234363
-
Modulation of anxiety through blockade of anandamide hydrolysis
-
Kathuria S, Gaetani S, Fegley D et al. (2003) Modulation of anxiety through blockade of anandamide hydrolysis. Nat Med 9:76-81
-
(2003)
Nat Med
, vol.9
, pp. 76-81
-
-
Kathuria, S.1
Gaetani, S.2
Fegley, D.3
-
49
-
-
0034747415
-
Selective cannabinoid CB1 receptor activation inhibits spinal nociceptive transmission in vivo
-
Kelly S, Chapman V (2001) Selective cannabinoid CB1 receptor activation inhibits spinal nociceptive transmission in vivo. J Neurophysiol 86:3061-3064
-
(2001)
J Neurophysiol
, vol.86
, pp. 3061-3064
-
-
Kelly, S.1
Chapman, V.2
-
50
-
-
0037052626
-
Spinal administration of capsazepine inhibits noxious evoked responses of dorsal horn neurons in non-inflamed and carrageenan inflamed rats
-
Kelly S, Chapman V (2002) Spinal administration of capsazepine inhibits noxious evoked responses of dorsal horn neurons in non-inflamed and carrageenan inflamed rats. Brain Res 935:103-108
-
(2002)
Brain Res
, vol.935
, pp. 103-108
-
-
Kelly, S.1
Chapman, V.2
-
51
-
-
0142102352
-
Cannabinoid CB(1) receptor inhibition of mechanically evoked responses of spinal neurones in control rats, but not in rats with hindpaw inflammation
-
Kelly S, Chapman V (2003) Cannabinoid CB(1) receptor inhibition of mechanically evoked responses of spinal neurones in control rats, but not in rats with hindpaw inflammation. Eur J Pharmacol 474:209-216
-
(2003)
Eur J Pharmacol
, vol.474
, pp. 209-216
-
-
Kelly, S.1
Chapman, V.2
-
52
-
-
1642422400
-
Activation of peripheral cannabinoid CB1 receptors inhibits mechanically evoked responses of spinal neurons in noninflamed rats and rats with hindpaw inflammation
-
Kelly S, Jhaveri MD, Sagar DR et al. (2003) Activation of peripheral cannabinoid CB1 receptors inhibits mechanically evoked responses of spinal neurons in noninflamed rats and rats with hindpaw inflammation. Eur J Neurosci 18:2239-2243
-
(2003)
Eur J Neurosci
, vol.18
, pp. 2239-2243
-
-
Kelly, S.1
Jhaveri, M.D.2
Sagar, D.R.3
-
53
-
-
40649102938
-
GPR55 is a cannabinoid receptor that increases intracellular calcium and inhibits M current
-
Lauckner JE, Jensen JB, Chen HY et al. (2008) GPR55 is a cannabinoid receptor that increases intracellular calcium and inhibits M current. Proc Natl Acad Sci USA 105:2699-2704
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 2699-2704
-
-
Lauckner, J.E.1
Jensen, J.B.2
Chen, H.Y.3
-
54
-
-
33645935391
-
Inactivation of N-acyl phosphatidylethanolamine phospholipase D reveals multiple mechanisms for the biosynthesis of endocannabinoids
-
Leung D, Saghatelian A, Simon GMet al. (2006) Inactivation of N-acyl phosphatidylethanolamine phospholipase D reveals multiple mechanisms for the biosynthesis of endocannabinoids. Biochemistry 45:4720-4726
-
(2006)
Biochemistry
, vol.45
, pp. 4720-4726
-
-
Leung, D.1
Saghatelian, A.2
Simon, G.M.3
-
55
-
-
0030087731
-
Investigation of brain sites mediating cannabinoidinduced antinociception in rats: Evidence supporting periaqueductal gray involvement
-
Lichtman AH, Cook SA, Martin BR (1996) Investigation of brain sites mediating cannabinoidinduced antinociception in rats: evidence supporting periaqueductal gray involvement. J Pharmacol Exp Ther 276:585-593
-
(1996)
J Pharmacol Exp Ther
, vol.276
, pp. 585-593
-
-
Lichtman, A.H.1
Cook, S.A.2
Martin, B.R.3
-
56
-
-
4644354869
-
Reversible inhibitors of fatty acid amide hydrolase that promote analgesia: Evidence for an unprecedented combination of potency and selectivity
-
Lichtman AH, Leung D, Shelton CC et al. (2004a) Reversible inhibitors of fatty acid amide hydrolase that promote analgesia: evidence for an unprecedented combination of potency and selectivity. J Pharmacol Exp Ther 311:441-448
-
(2004)
J Pharmacol Exp Ther
, vol.311
, pp. 441-448
-
-
Lichtman, A.H.1
Leung, D.2
Shelton, C.C.3
-
57
-
-
2442510225
-
Mice lacking fatty acid amide hydrolase exhibit a cannabinoid receptor-mediated phenotypic hypoalgesia
-
Lichtman AH, Shelton CC, Advani T et al. (2004b) Mice lacking fatty acid amide hydrolase exhibit a cannabinoid receptor-mediated phenotypic hypoalgesia. Pain 109:319-327
-
(2004)
Pain
, vol.109
, pp. 319-327
-
-
Lichtman, A.H.1
Shelton, C.C.2
Advani, T.3
-
59
-
-
37349020974
-
Multiple pathways involved in the biosynthesis of anandamide
-
Liu J, Wang L, Harvey-White J et al. (2008) Multiple pathways involved in the biosynthesis of anandamide. Neuropharmacology 54:1-7
-
(2008)
Neuropharmacology
, vol.54
, pp. 1-7
-
-
Liu, J.1
Wang, L.2
Harvey-White, J.3
-
60
-
-
33144480327
-
Cannabinoid receptors as therapeutic targets
-
Mackie K (2006) Cannabinoid receptors as therapeutic targets. Annu Rev Pharmacol Toxicol 46:101-122
-
(2006)
Annu Rev Pharmacol Toxicol
, vol.46
, pp. 101-122
-
-
Mackie, K.1
-
61
-
-
33947319316
-
Analgesic actions of N-arachidonoylserotonin, a fatty acid amide hydrolase inhibitor with antagonistic activity at vanilloid TRPV1 receptors
-
Maione S, De Petrocellis L, de Novellis V et al. (2007) Analgesic actions of N-arachidonoylserotonin, a fatty acid amide hydrolase inhibitor with antagonistic activity at vanilloid TRPV1 receptors. Br J Pharmacol 150:766-781
-
(2007)
Br J Pharmacol
, vol.150
, pp. 766-781
-
-
Maione, S.1
de Petrocellis, L.2
de Novellis, V.3
-
62
-
-
0034886018
-
CB2 cannabinoid receptor-mediated peripheral antinociception
-
Malan TP Jr, Ibrahim MM, Deng H et al. (2001) CB2 cannabinoid receptor-mediated peripheral antinociception. Pain 93:239-245
-
(2001)
Pain
, vol.93
, pp. 239-245
-
-
Malan Jr., T.P.1
Ibrahim, M.M.2
Deng, H.3
-
63
-
-
0037302086
-
CB2 cannabinoid receptor agonists: Pain relief without psychoactive effects?
-
Malan TP Jr, Ibrahim MM, Lai J et al. (2003) CB2 cannabinoid receptor agonists: pain relief without psychoactive effects? Curr Opin Pharmacol 3:62-67
-
(2003)
Curr Opin Pharmacol
, vol.3
, pp. 62-67
-
-
Malan Jr., T.P.1
Ibrahim, M.M.2
Lai, J.3
-
64
-
-
0033586315
-
Anatomical basis for cannabinoid-induced antinociception as revealed by intracerebral microinjections
-
Martin WJ, Coffin PO, Attias E et al. (1999) Anatomical basis for cannabinoid-induced antinociception as revealed by intracerebral microinjections. Brain Res 822:237-242
-
(1999)
Brain Res
, vol.822
, pp. 237-242
-
-
Martin, W.J.1
Coffin, P.O.2
Attias, E.3
-
65
-
-
0029012014
-
Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors
-
Mechoulam R, Ben-Shabat S, Hanus L et al. (1995) Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors. Biochem Pharmacol 50:83-90
-
(1995)
Biochem Pharmacol
, vol.50
, pp. 83-90
-
-
Mechoulam, R.1
Ben-Shabat, S.2
Hanus, L.3
-
66
-
-
0032563792
-
An analgesia circuit activated by cannabinoids
-
Meng ID, Manning BH, Martin WJ et al. (1998) An analgesia circuit activated by cannabinoids. Nature 395:381-383
-
(1998)
Nature
, vol.395
, pp. 381-383
-
-
Meng, I.D.1
Manning, B.H.2
Martin, W.J.3
-
67
-
-
33751244807
-
Site-specific increases in peripheral cannabinoid receptors and their endogenous ligands in a model of neuropathic pain
-
Mitrirattanakul S, Ramakul N, Guerrero AV et al. (2006) Site-specific increases in peripheral cannabinoid receptors and their endogenous ligands in a model of neuropathic pain. Pain 126:102-114
-
(2006)
Pain
, vol.126
, pp. 102-114
-
-
Mitrirattanakul, S.1
Ramakul, N.2
Guerrero, A.V.3
-
68
-
-
31444437185
-
Peripheral cannabinoid receptor, CB2, regulates bone mass
-
Ofek O, Karsak M, Leclerc N et al. (2006) Peripheral cannabinoid receptor, CB2, regulates bone mass. Proc Natl Acad Sci USA 103:696-701
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 696-701
-
-
Ofek, O.1
Karsak, M.2
Leclerc, N.3
-
69
-
-
0035150352
-
Cannabinoid receptors and pain
-
Pertwee RG (2001) Cannabinoid receptors and pain. Prog Neurobiol 63:569-611
-
(2001)
Prog Neurobiol
, vol.63
, pp. 569-611
-
-
Pertwee, R.G.1
-
70
-
-
33846389346
-
Changes in spinal and supraspinal endocannabinoid levels in neuropathic rats
-
Petrosino S, Palazzo E, de Novellis V et al. (2007) Changes in spinal and supraspinal endocannabinoid levels in neuropathic rats. Neuropharmacology 52:415-422
-
(2007)
Neuropharmacology
, vol.52
, pp. 415-422
-
-
Petrosino, S.1
Palazzo, E.2
de Novellis, V.3
-
71
-
-
0036260823
-
Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at theCB1 receptor
-
Porter AC, Sauer JM, Knierman MD et al. (2002) Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at theCB1 receptor. J Pharmacol Exp Ther 301:1020-1024
-
(2002)
J Pharmacol Exp Ther
, vol.301
, pp. 1020-1024
-
-
Porter, A.C.1
Sauer, J.M.2
Knierman, M.D.3
-
73
-
-
0031779305
-
Cannabinoids reduce hyperalgesia and inflammation via interaction with peripheral CB1 receptors
-
Richardson JD, Kilo S, Hargreaves KM (1998) Cannabinoids reduce hyperalgesia and inflammation via interaction with peripheral CB1 receptors. Pain 75:111-119
-
(1998)
Pain
, vol.75
, pp. 111-119
-
-
Richardson, J.D.1
Kilo, S.2
Hargreaves, K.M.3
-
74
-
-
43249115359
-
Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis
-
Richardson D, Pearson RG, Kurian N et al. (2008) Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis. Arthritis Res Ther 10:R43
-
(2008)
Arthritis Res Ther
, vol.10
-
-
Richardson, D.1
Pearson, R.G.2
Kurian, N.3
-
75
-
-
41149137558
-
Spinal microglial and perivascular cell cannabinoid receptor type 2 activation reduces behavioral hypersensitivity without tolerance after peripheral nerve injury
-
Romero-Sandoval A, Nutile-McMenemy N, DeLeo JA (2008) Spinal microglial and perivascular cell cannabinoid receptor type 2 activation reduces behavioral hypersensitivity without tolerance after peripheral nerve injury. Anesthesiology 108:722-734
-
(2008)
Anesthesiology
, vol.108
, pp. 722-734
-
-
Romero-Sandoval, A.1
Nutile-McMenemy, N.2
DeLeo, J.A.3
-
76
-
-
34250750792
-
The fatty-acid amide hydrolase inhibitor URB597 (cyclohexyl carbamic acid 30-carbamoyl-biphenyl-3-yl ester) reduces neuropathic pain after oral administration in mice
-
Russo R, Loverme J, La Rana G et al. (2007) The fatty-acid amide hydrolase inhibitor URB597 (cyclohexyl carbamic acid 30-carbamoyl-biphenyl-3-yl ester) reduces neuropathic pain after oral administration in mice. J Pharmacol Exp Ther 322:236-242
-
(2007)
J Pharmacol Exp Ther
, vol.322
, pp. 236-242
-
-
Russo, R.1
Loverme, J.2
La Rana, G.3
-
77
-
-
35649015179
-
The orphan receptor GPR55 is a novel cannabinoid receptor
-
Ryberg E, Larsson N, Sjogren S et al. (2007) The orphan receptor GPR55 is a novel cannabinoid receptor. Br J Pharmacol 152:1092-1101
-
(2007)
Br J Pharmacol
, vol.152
, pp. 1092-1101
-
-
Ryberg, E.1
Larsson, N.2
Sjogren, S.3
-
78
-
-
23244444097
-
Inhibitory effects of CB1 and CB2 receptor agonists on responses of DRG neurons and dorsal horn neurons in neuropathic rats
-
Sagar DR, Kelly S, Millns PJ et al. (2005) Inhibitory effects of CB1 and CB2 receptor agonists on responses of DRG neurons and dorsal horn neurons in neuropathic rats. Eur J Neurosci 22:371-379
-
(2005)
Eur J Neurosci
, vol.22
, pp. 371-379
-
-
Sagar, D.R.1
Kelly, S.2
Millns, P.J.3
-
79
-
-
38149076483
-
Cannabinoid-mediated antinociception is enhanced in rat osteoarthritic knees
-
Schuelert N, McDougall JJ (2008) Cannabinoid-mediated antinociception is enhanced in rat osteoarthritic knees. Arthritis Rheum 58:145-153
-
(2008)
Arthritis Rheum
, vol.58
, pp. 145-153
-
-
Schuelert, N.1
McDougall, J.J.2
-
80
-
-
1842685334
-
Evidence that CB-1 and CB-2 cannabinoid receptors mediate antinociception in neuropathic pain in the rat
-
Scott DA, Wright CE, Angus JA (2004) Evidence that CB-1 and CB-2 cannabinoid receptors mediate antinociception in neuropathic pain in the rat. Pain 109:124-131
-
(2004)
Pain
, vol.109
, pp. 124-131
-
-
Scott, D.A.1
Wright, C.E.2
Angus, J.A.3
-
81
-
-
44049087532
-
Anandamide biosynthesis catalyzed by the phosphodiesterase GDE1 and detection of glycerophospho-N-acyl ethanolamine precursors in mouse brain
-
Simon GM, Cravatt BF (2008) Anandamide biosynthesis catalyzed by the phosphodiesterase GDE1 and detection of glycerophospho-N-acyl ethanolamine precursors in mouse brain. J Biol Chem 283:9341-9349
-
(2008)
J Biol Chem
, vol.283
, pp. 9341-9349
-
-
Simon, G.M.1
Cravatt, B.F.2
-
82
-
-
0032056333
-
Characterization of delta9-tetrahydrocannabinol and anandamide antinociception in nonarthritic and arthritic rats
-
Smith FL, Fujimori K, Lowe J et al. (1998) Characterization of delta9-tetrahydrocannabinol and anandamide antinociception in nonarthritic and arthritic rats. Pharmacol Biochem Behav 60:183-191
-
(1998)
Pharmacol Biochem Behav
, vol.60
, pp. 183-191
-
-
Smith, F.L.1
Fujimori, K.2
Lowe, J.3
-
83
-
-
0037966402
-
Intraplantar injection of anandamide inhibits mechanically-evoked responses of spinal neurones via activation of CB2 receptors in anaesthetised rats
-
Sokal DM, Elmes SJ, Kendall DA et al. (2003) Intraplantar injection of anandamide inhibits mechanically-evoked responses of spinal neurones via activation of CB2 receptors in anaesthetised rats. Neuropharmacology 45:404-411
-
(2003)
Neuropharmacology
, vol.45
, pp. 404-411
-
-
Sokal, D.M.1
Elmes, S.J.2
Kendall, D.A.3
-
84
-
-
33747598488
-
Involvement of neuronal cannabinoid receptor CB1 in regulation of bone mass and bone remodeling
-
Tam J, Ofek O, Fride E et al. (2006) Involvement of neuronal cannabinoid receptor CB1 in regulation of bone mass and bone remodeling. Mol Pharmacol 70:786-792
-
(2006)
Mol Pharmacol
, vol.70
, pp. 786-792
-
-
Tam, J.1
Ofek, O.2
Fride, E.3
-
85
-
-
0031929438
-
Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous system
-
Tsou K, Brown S, Sanudo-Pena MC et al. (1998) Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous system. Neuroscience 83:393-411
-
(1998)
Neuroscience
, vol.83
, pp. 393-411
-
-
Tsou, K.1
Brown, S.2
Sanudo-Pena, M.C.3
-
86
-
-
34548513526
-
The N-acylethanolamine-hydrolyzing acid amidase (NAAA)
-
Tsuboi K, Takezaki N, Ueda N (2007) The N-acylethanolamine-hydrolyzing acid amidase (NAAA). Chem Biodivers 4:1914-1925
-
(2007)
Chem Biodivers
, vol.4
, pp. 1914-1925
-
-
Tsuboi, K.1
Takezaki, N.2
Ueda, N.3
-
87
-
-
20144388149
-
Pharmacological and pharmacokinetic characterization of the cannabinoid receptor 2 agonist, GW405833, utilizing rodent models of acute and chronic pain, anxiety, ataxia and catalepsy
-
Valenzano KJ, Tafesse L, Lee G et al. (2005) Pharmacological and pharmacokinetic characterization of the cannabinoid receptor 2 agonist, GW405833, utilizing rodent models of acute and chronic pain, anxiety, ataxia and catalepsy. Neuropharmacology 48:658-672
-
(2005)
Neuropharmacology
, vol.48
, pp. 658-672
-
-
Valenzano, K.J.1
Tafesse, L.2
Lee, G.3
-
88
-
-
26844504226
-
Identification and functional characterization of brainstem cannabinoid CB2 receptors
-
Van Sickle MD, Duncan M, Kingsley PJ et al. (2005) Identification and functional characterization of brainstem cannabinoid CB2 receptors. Science 310:329-332
-
(2005)
Science
, vol.310
, pp. 329-332
-
-
van Sickle, M.D.1
Duncan, M.2
Kingsley, P.J.3
-
90
-
-
0032716177
-
Pain modulation by release of the endogenous cannabinoid anandamide
-
Walker JM, Huang SM, Strangman NMet al. (1999) Pain modulation by release of the endogenous cannabinoid anandamide. Proc Natl Acad Sci USA 96:12198-12203
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 12198-12203
-
-
Walker, J.M.1
Huang, S.M.2
Strangman, N.M.3
-
91
-
-
0026639295
-
Antinociceptive activity of intrathecally administered cannabinoids alone, and in combination with morphine, in mice
-
Welch SP, Stevens DL (1992) Antinociceptive activity of intrathecally administered cannabinoids alone, and in combination with morphine, in mice. J Pharmacol Exp Ther 262:10-18
-
(1992)
J Pharmacol Exp Ther
, vol.262
, pp. 10-18
-
-
Welch, S.P.1
Stevens, D.L.2
-
92
-
-
0032160418
-
Differential blockade of the antinociceptive effects of centrally administered cannabinoids by SR141716A
-
Welch SP, Huffman JW, Lowe J (1998) Differential blockade of the antinociceptive effects of centrally administered cannabinoids by SR141716A. J Pharmacol Exp Ther 286:1301-1308
-
(1998)
J Pharmacol Exp Ther
, vol.286
, pp. 1301-1308
-
-
Welch, S.P.1
Huffman, J.W.2
Lowe, J.3
-
93
-
-
33745618444
-
The use of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis
-
(Oxford) author reply 781-782
-
Wright S, Ware M, Guy G (2006) The use of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis. Rheumatology (Oxford) 45, 781; author reply 781-782
-
(2006)
Rheumatology
, vol.45
, pp. 781
-
-
Wright, S.1
Ware, M.2
Guy, G.3
-
94
-
-
39749122600
-
Involvement of central cannabinoid CB2 receptor in reducing mechanical allodynia in a mouse model of neuropathic pain
-
Yamamoto W, Mikami T, Iwamura H (2008) Involvement of central cannabinoid CB2 receptor in reducing mechanical allodynia in a mouse model of neuropathic pain. Eur J Pharmacol 583:56-61
-
(2008)
Eur J Pharmacol
, vol.583
, pp. 56-61
-
-
Yamamoto, W.1
Mikami, T.2
Iwamura, H.3
|