메뉴 건너뛰기




Volumn 1, Issue , 2009, Pages 275-287

Targeting the Cannabinoid system to produce Analgesia

Author keywords

Arthritis; Endocannabinoid; Fatty acid amide hydrolase; Inflammation; Neuropathic

Indexed keywords

AMIDASE; CANNABINOID; CANNABINOID RECEPTOR; ENDOCANNABINOID; FATTY ACID AMIDASE; FATTY-ACID AMIDE HYDROLASE;

EID: 79952118399     PISSN: 18663370     EISSN: 18663389     Source Type: Book Series    
DOI: 10.1007/978-3-540-88955-7_11     Document Type: Article
Times cited : (10)

References (94)
  • 1
    • 34347342722 scopus 로고    scopus 로고
    • Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors
    • Agarwal N, Pacher P, Tegeder I et al. (2007) Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors. Nat Neurosci 10:870-879
    • (2007) Nat Neurosci , vol.10 , pp. 870-879
    • Agarwal, N.1    Pacher, P.2    Tegeder, I.3
  • 2
    • 42349086864 scopus 로고    scopus 로고
    • Endocannabinoids and the regulation of bone metabolism
    • Bab I, Ofek O, Tam J et al. (2008) Endocannabinoids and the regulation of bone metabolism. J Neuroendocrinol 20(Suppl 1):69-74
    • (2008) J Neuroendocrinol , vol.20 , Issue.SUPPL.1 , pp. 69-74
    • Bab, I.1    Ofek, O.2    Tam, J.3
  • 3
    • 0034685843 scopus 로고    scopus 로고
    • Role of the endogenous cannabinoid system in the formalin test of persistent pain in the rat
    • Beaulieu P, Bisogno T, Punwar S et al. (2000) Role of the endogenous cannabinoid system in the formalin test of persistent pain in the rat. Eur J Pharmacol 396:85-92
    • (2000) Eur J Pharmacol , vol.396 , pp. 85-92
    • Beaulieu, P.1    Bisogno, T.2    Punwar, S.3
  • 4
    • 33645106816 scopus 로고    scopus 로고
    • CB2 receptor-mediated antihyperalgesia: Possible direct involvement of neural mechanisms
    • Beltramo M, Bernardini N, Bertorelli R et al. (2006) CB2 receptor-mediated antihyperalgesia: possible direct involvement of neural mechanisms. Eur J Neurosci 23:1530-1538
    • (2006) Eur J Neurosci , vol.23 , pp. 1530-1538
    • Beltramo, M.1    Bernardini, N.2    Bertorelli, R.3
  • 5
    • 29844435136 scopus 로고    scopus 로고
    • Preliminary assessment of the efficacy, tolerability and safety of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis
    • Blake DR, Robson P, Ho M et al. (2006) Preliminary assessment of the efficacy, tolerability and safety of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis. Rheumatology (Oxford) 45:50-52
    • (2006) Rheumatology (Oxford) , vol.45 , pp. 50-52
    • Blake, D.R.1    Robson, P.2    Ho, M.3
  • 6
    • 35748973885 scopus 로고    scopus 로고
    • Novel cannabinoid receptors
    • Brown AJ (2007) Novel cannabinoid receptors. Br J Pharmacol 152:567-575
    • (2007) Br J Pharmacol , vol.152 , pp. 567-575
    • Brown, A.J.1
  • 7
    • 33646431125 scopus 로고    scopus 로고
    • Inhibition of fatty acid amide hydrolase produces analgesia by multiple mechanisms
    • Chang L, Luo L, Palmer JA et al. (2006) Inhibition of fatty acid amide hydrolase produces analgesia by multiple mechanisms. Br J Pharmacol 148:102-113
    • (2006) Br J Pharmacol , vol.148 , pp. 102-113
    • Chang, L.1    Luo, L.2    Palmer, J.A.3
  • 8
    • 0032588146 scopus 로고    scopus 로고
    • The cannabinoid CB1 receptor antagonist, SR141716A, selectively facilitates nociceptive responses of dorsal horn neurones in the rat
    • Chapman V (1999) The cannabinoid CB1 receptor antagonist, SR141716A, selectively facilitates nociceptive responses of dorsal horn neurones in the rat. Br J Pharmacol 127:1765-1767
    • (1999) Br J Pharmacol , vol.127 , pp. 1765-1767
    • Chapman, V.1
  • 9
    • 38349117232 scopus 로고    scopus 로고
    • Differential effects of cannabinoid receptor agonists on regional brain activity using pharmacological MRI
    • Chin CL, Tovcimak AE, Hradil VP et al. (2008) Differential effects of cannabinoid receptor agonists on regional brain activity using pharmacological MRI. Br J Pharmacol 153:367-379
    • (2008) Br J Pharmacol , vol.153 , pp. 367-379
    • Chin, C.L.1    Tovcimak, A.E.2    Hradil, V.P.3
  • 10
    • 0036221971 scopus 로고    scopus 로고
    • CB1 and CB2 cannabinoid receptors are implicated in inflammatory pain
    • Clayton N, Marshall FH, Bountra C et al. (2002) CB1 and CB2 cannabinoid receptors are implicated in inflammatory pain. Pain 96:253-260
    • (2002) Pain , vol.96 , pp. 253-260
    • Clayton, N.1    Marshall, F.H.2    Bountra, C.3
  • 11
    • 2942579681 scopus 로고    scopus 로고
    • The antinociceptive effect of Delta9-tetrahydrocannabinol in the arthritic rat
    • Cox ML, Welch SP (2004) The antinociceptive effect of Delta9-tetrahydrocannabinol in the arthritic rat. Eur J Pharmacol 493:65-74
    • (2004) Eur J Pharmacol , vol.493 , pp. 65-74
    • Cox, M.L.1    Welch, S.P.2
  • 12
    • 34547837599 scopus 로고    scopus 로고
    • The antinociceptive effect of Delta9-tetrahydrocannabinol in the arthritic rat involves the CB(2) cannabinoid receptor
    • Cox ML, Haller VL, Welch SP (2007a) The antinociceptive effect of Delta9-tetrahydrocannabinol in the arthritic rat involves the CB(2) cannabinoid receptor. Eur J Pharmacol 570:50-56
    • (2007) Eur J Pharmacol , vol.570 , pp. 50-56
    • Cox, M.L.1    Haller, V.L.2    Welch, S.P.3
  • 13
    • 34249108566 scopus 로고    scopus 로고
    • Synergy between delta9-tetrahydrocannabinol and morphine in the arthritic rat
    • Cox ML, Haller VL, Welch SP (2007b) Synergy between delta9-tetrahydrocannabinol and morphine in the arthritic rat. Eur J Pharmacol 567:125-130
    • (2007) Eur J Pharmacol , vol.567 , pp. 125-130
    • Cox, M.L.1    Haller, V.L.2    Welch, S.P.3
  • 14
    • 0029904838 scopus 로고    scopus 로고
    • Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides
    • Cravatt BF, Giang DK, Mayfield SP et al. (1996) Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides. Nature 384:83-87
    • (1996) Nature , vol.384 , pp. 83-87
    • Cravatt, B.F.1    Giang, D.K.2    Mayfield, S.P.3
  • 15
    • 0035979244 scopus 로고    scopus 로고
    • Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase
    • Cravatt BF, Demarest K, Patricelli MP et al. (2001) Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase. Proc Natl Acad Sci USA 98:9371-9376
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 9371-9376
    • Cravatt, B.F.1    Demarest, K.2    Patricelli, M.P.3
  • 16
    • 0027180394 scopus 로고
    • Enzymatic synthesis and degradation of anandamide, a cannabinoid receptor agonist
    • Deutsch DG, Chin SA (1993) Enzymatic synthesis and degradation of anandamide, a cannabinoid receptor agonist. Biochem Pharmacol 46:791-796
    • (1993) Biochem Pharmacol , vol.46 , pp. 791-796
    • Deutsch, D.G.1    Chin, S.A.2
  • 17
    • 0027078685 scopus 로고
    • Isolation and structure of a brain constituent that binds to the cannabinoid receptor
    • Devane WA, Hanus L, Breuer A et al. (1992) Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science 258:1946-1949
    • (1992) Science , vol.258 , pp. 1946-1949
    • Devane, W.A.1    Hanus, L.2    Breuer, A.3
  • 18
    • 0036678094 scopus 로고    scopus 로고
    • Brain monoglyceride lipase participating in endocannabinoid inactivation
    • Dinh TP, Carpenter D, Leslie FM et al. (2002) Brain monoglyceride lipase participating in endocannabinoid inactivation. Proc Natl Acad Sci USA 99:10819-10824
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 10819-10824
    • Dinh, T.P.1    Carpenter, D.2    Leslie, F.M.3
  • 19
    • 0034717944 scopus 로고    scopus 로고
    • Localisation of cannabinoid receptors in the rat brain using antibodies to the intracellular C-terminal tail of CB
    • Egertova M, Elphick MR (2000) Localisation of cannabinoid receptors in the rat brain using antibodies to the intracellular C-terminal tail of CB. J Comp Neurol 422:159-171
    • (2000) J Comp Neurol , vol.422 , pp. 159-171
    • Egertova, M.1    Elphick, M.R.2
  • 20
    • 8144229133 scopus 로고    scopus 로고
    • Cannabinoid CB2 receptor activation inhibits mechanically evoked responses of wide dynamic range dorsal horn neurons in naive rats and in rat models of inflammatory and neuropathic pain
    • Elmes SJ, JhaveriMD, Smart D et al. (2004) Cannabinoid CB2 receptor activation inhibits mechanically evoked responses of wide dynamic range dorsal horn neurons in naive rats and in rat models of inflammatory and neuropathic pain. Eur J Neurosci 20:2311-2320
    • (2004) Eur J Neurosci , vol.20 , pp. 2311-2320
    • Elmes, S.J.1    Jhaveri, M.D.2    Smart, D.3
  • 21
    • 28644451441 scopus 로고    scopus 로고
    • Activation of CB1 and CB2 receptors attenuates the induction and maintenance of inflammatory pain in the rat
    • Elmes SJ, Winyard LA, Medhurst SJ et al. (2005) Activation of CB1 and CB2 receptors attenuates the induction and maintenance of inflammatory pain in the rat. Pain 118:327-335
    • (2005) Pain , vol.118 , pp. 327-335
    • Elmes, S.J.1    Winyard, L.A.2    Medhurst, S.J.3
  • 22
    • 15744385109 scopus 로고    scopus 로고
    • Characterization of the fatty acid amide hydrolase inhibitor cyclohexyl carbamic acid 30-carbamoyl-biphenyl-3-yl ester (URB597): Effects on anandamide and oleoylethanolamide deactivation
    • Fegley D, Gaetani S, Duranti A et al. (2005) Characterization of the fatty acid amide hydrolase inhibitor cyclohexyl carbamic acid 30-carbamoyl-biphenyl-3-yl ester (URB597): effects on anandamide and oleoylethanolamide deactivation. J Pharmacol Exp Ther 313:352-358
    • (2005) J Pharmacol Exp Ther , vol.313 , pp. 352-358
    • Fegley, D.1    Gaetani, S.2    Duranti, A.3
  • 23
    • 0043073239 scopus 로고    scopus 로고
    • Effects of direct periaqueductal grey administration of a cannabinoid receptor agonist on nociceptive and aversive responses in rats
    • Finn DP, Jhaveri MD, Beckett SR et al. (2003) Effects of direct periaqueductal grey administration of a cannabinoid receptor agonist on nociceptive and aversive responses in rats. Neuropharmacology 45:594-604
    • (2003) Neuropharmacology , vol.45 , pp. 594-604
    • Finn, D.P.1    Jhaveri, M.D.2    Beckett, S.R.3
  • 24
    • 35649011495 scopus 로고    scopus 로고
    • The contribution of cyclooxygenase-2 to endocannabinoid metabolism and action
    • Fowler CJ (2007) The contribution of cyclooxygenase-2 to endocannabinoid metabolism and action. Br J Pharmacol 152:594-601
    • (2007) Br J Pharmacol , vol.152 , pp. 594-601
    • Fowler, C.J.1
  • 25
    • 0029094470 scopus 로고
    • Expression of central and peripheral cannabinoid receptors in human immune tissues and leukocyte subpopulations
    • Galiegue S, Mary S, Marchand J et al. (1995) Expression of central and peripheral cannabinoid receptors in human immune tissues and leukocyte subpopulations. Eur J Biochem 232:54-61
    • (1995) Eur J Biochem , vol.232 , pp. 54-61
    • Galiegue, S.1    Mary, S.2    Marchand, J.3
  • 26
    • 0035112856 scopus 로고    scopus 로고
    • Anandamide activates peripheral nociceptors in normal and arthritic rat knee joints
    • Gauldie SD, McQueen DS, Pertwee R et al. (2001) Anandamide activates peripheral nociceptors in normal and arthritic rat knee joints. Br J Pharmacol 132:617-621
    • (2001) Br J Pharmacol , vol.132 , pp. 617-621
    • Gauldie, S.D.1    McQueen, D.S.2    Pertwee, R.3
  • 27
    • 32844465920 scopus 로고    scopus 로고
    • Cannabinoid CB2 receptors: Immunohistochemical localization in rat brain
    • Gong JP, Onaivi ES, Ishiguro H et al. (2006) Cannabinoid CB2 receptors: immunohistochemical localization in rat brain. Brain Res 1071:10-23
    • (2006) Brain Res , vol.1071 , pp. 10-23
    • Gong, J.P.1    Onaivi, E.S.2    Ishiguro, H.3
  • 28
    • 38349119715 scopus 로고    scopus 로고
    • Cannabinoid CB2 receptors: A therapeutic target for the treatment of inflammatory and neuropathic pain
    • Guindon J, Hohmann AG (2008) Cannabinoid CB2 receptors: a therapeutic target for the treatment of inflammatory and neuropathic pain. Br J Pharmacol 153:319-334
    • (2008) Br J Pharmacol , vol.153 , pp. 319-334
    • Guindon, J.1    Hohmann, A.G.2
  • 29
    • 33947302244 scopus 로고    scopus 로고
    • The antinociceptive effects of intraplantar injections of 2-arachidonoyl glycerol are mediated by cannabinoid CB2 receptors
    • Guindon J, Desroches J, Beaulieu P (2007) The antinociceptive effects of intraplantar injections of 2-arachidonoyl glycerol are mediated by cannabinoid CB2 receptors. Br J Pharmacol 150:693-701
    • (2007) Br J Pharmacol , vol.150 , pp. 693-701
    • Guindon, J.1    Desroches, J.2    Beaulieu, P.3
  • 30
    • 0035957425 scopus 로고    scopus 로고
    • 2-Arachidonyl glyceryl ether, an endogenous agonist of the cannabinoid CB1 receptor
    • Hanus L, Abu-Lafi S, Fride E et al. (2001) 2-Arachidonyl glyceryl ether, an endogenous agonist of the cannabinoid CB1 receptor. Proc Natl Acad Sci USA 98:3662-3665
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 3662-3665
    • Hanus, L.1    Abu-Lafi, S.2    Fride, E.3
  • 31
    • 0034699017 scopus 로고    scopus 로고
    • Spinal anandamide inhibits nociceptive transmission via cannabinoid receptor activation in vivo
    • Harris J, Drew LJ, Chapman V (2000) Spinal anandamide inhibits nociceptive transmission via cannabinoid receptor activation in vivo. NeuroReport 11:2817-2819
    • (2000) NeuroReport , vol.11 , pp. 2817-2819
    • Harris, J.1    Drew, L.J.2    Chapman, V.3
  • 32
    • 0025760879 scopus 로고
    • Neuronal localization of cannabinoid receptors and second messengers in mutant mouse cerebellum
    • Herkenham M, Groen BG, Lynn AB et al. (1991) Neuronal localization of cannabinoid receptors and second messengers in mutant mouse cerebellum. Brain Res 552:301-310
    • (1991) Brain Res , vol.552 , pp. 301-310
    • Herkenham, M.1    Groen, B.G.2    Lynn, A.B.3
  • 33
    • 0037207078 scopus 로고    scopus 로고
    • Spinal and peripheral mechanisms of cannabinoid antinociception: Behavioral, neurophysiological and neuroanatomical perspectives
    • Hohmann AG (2002) Spinal and peripheral mechanisms of cannabinoid antinociception: behavioral, neurophysiological and neuroanatomical perspectives. Chem Phys Lipids 121:173-190
    • (2002) Chem Phys Lipids , vol.121 , pp. 173-190
    • Hohmann, A.G.1
  • 34
    • 0032484245 scopus 로고    scopus 로고
    • Cannabinoid modulation of wide dynamic range neurons in the lumbar dorsal horn of the rat by spinally administered WIN55, 212-2
    • Hohmann AG, Tsou K, Walker JM (1998) Cannabinoid modulation of wide dynamic range neurons in the lumbar dorsal horn of the rat by spinally administered WIN55, 212-2. Neurosci Lett 257:119-122
    • (1998) Neurosci Lett , vol.257 , pp. 119-122
    • Hohmann, A.G.1    Tsou, K.2    Walker, J.M.3
  • 35
    • 27144431754 scopus 로고    scopus 로고
    • Inhibitors of fatty acid amide hydrolase reduce carrageenaninduced hind paw inflammation in pentobarbital-treated mice: Comparison with indomethacin and possible involvement of cannabinoid receptors
    • Holt S, Comelli F, Costa B et al. (2005) Inhibitors of fatty acid amide hydrolase reduce carrageenaninduced hind paw inflammation in pentobarbital-treated mice: comparison with indomethacin and possible involvement of cannabinoid receptors. Br J Pharmacol 146:467-476
    • (2005) Br J Pharmacol , vol.146 , pp. 467-476
    • Holt, S.1    Comelli, F.2    Costa, B.3
  • 36
    • 0037062411 scopus 로고    scopus 로고
    • An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors
    • Huang SM, Bisogno T, Trevisani M et al. (2002) An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors. Proc Natl Acad Sci USA 99:8400-8405
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 8400-8405
    • Huang, S.M.1    Bisogno, T.2    Trevisani, M.3
  • 37
    • 20044368975 scopus 로고    scopus 로고
    • CB2 cannabinoid receptor activation produces antinociception by stimulating peripheral release of endogenous opioids
    • Ibrahim MM, Porreca F, Lai J et al. (2005) CB2 cannabinoid receptor activation produces antinociception by stimulating peripheral release of endogenous opioids. Proc Natl Acad Sci USA 102:3093-3098
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 3093-3098
    • Ibrahim, M.M.1    Porreca, F.2    Lai, J.3
  • 38
    • 33646062552 scopus 로고    scopus 로고
    • CB2 cannabinoid receptor mediation of antinociception
    • Ibrahim MM, Rude ML, Stagg NJ et al. (2006) CB2 cannabinoid receptor mediation of antinociception. Pain 122:36-42
    • (2006) Pain , vol.122 , pp. 36-42
    • Ibrahim, M.M.1    Rude, M.L.2    Stagg, N.J.3
  • 39
    • 0036462447 scopus 로고    scopus 로고
    • Cannabinoids: A real prospect for pain relief?
    • Iversen L, Chapman V (2002) Cannabinoids: a real prospect for pain relief? Curr Opin Pharmacol 2:50-55
    • (2002) Curr Opin Pharmacol , vol.2 , pp. 50-55
    • Iversen, L.1    Chapman, V.2
  • 40
    • 32244432341 scopus 로고    scopus 로고
    • Actions of the FAAH inhibitor URB597 in neuropathic and inflammatory chronic pain models
    • Jayamanne A, Greenwood R, Mitchell VA et al. (2006) Actions of the FAAH inhibitor URB597 in neuropathic and inflammatory chronic pain models. Br J Pharmacol 147:281-288
    • (2006) Br J Pharmacol , vol.147 , pp. 281-288
    • Jayamanne, A.1    Greenwood, R.2    Mitchell, V.A.3
  • 41
    • 33845799619 scopus 로고    scopus 로고
    • Analgesic effects of fatty acid amide hydrolase inhibition in a rat model of neuropathic pain
    • Jhaveri MD, Richardson D, Kendall DA et al. (2006) Analgesic effects of fatty acid amide hydrolase inhibition in a rat model of neuropathic pain. J Neurosci 26:13318-13327
    • (2006) J Neurosci , vol.26 , pp. 13318-13327
    • Jhaveri, M.D.1    Richardson, D.2    Kendall, D.A.3
  • 42
    • 35648999552 scopus 로고    scopus 로고
    • Endocannabinoid metabolism and uptake: Novel targets for neuropathic and inflammatory pain
    • Jhaveri MD, Richardson D, Chapman V (2007a) Endocannabinoid metabolism and uptake: novel targets for neuropathic and inflammatory pain. Br J Pharmacol 152:624-632
    • (2007) Br J Pharmacol , vol.152 , pp. 624-632
    • Jhaveri, M.D.1    Richardson, D.2    Chapman, V.3
  • 43
    • 38449119121 scopus 로고    scopus 로고
    • Cannabinoid CB(2) receptor-mediated antinociception in models of acute and chronic pain
    • Jhaveri MD, Sagar DR, Elmes SJ et al. (2007b) Cannabinoid CB(2) receptor-mediated antinociception in models of acute and chronic pain. Mol Neurobiol 36:26-35
    • (2007) Mol Neurobiol , vol.36 , pp. 26-35
    • Jhaveri, M.D.1    Sagar, D.R.2    Elmes, S.J.3
  • 44
    • 41549099628 scopus 로고    scopus 로고
    • Evidence for a novel functional role of cannabinoid CB receptors in the thalamus of neuropathic rats
    • Jhaveri MD, Elmes SJ, Richardson D et al. (2008a) Evidence for a novel functional role of cannabinoid CB receptors in the thalamus of neuropathic rats. Eur J Neurosci 27:1722-1730
    • (2008) Eur J Neurosci , vol.27 , pp. 1722-1730
    • Jhaveri, M.D.1    Elmes, S.J.2    Richardson, D.3
  • 45
    • 45849106100 scopus 로고    scopus 로고
    • Inhibition of fatty acid amide hydrolase and cyclooxygenase-2 increases levels of endocannabinoid related molecules and produces analgesia via peroxisome proliferator-activated receptor-alpha in a model of inflammatory pain
    • Jhaveri MD, Richardson D, Robinson I et al. (2008b) Inhibition of fatty acid amide hydrolase and cyclooxygenase-2 increases levels of endocannabinoid related molecules and produces analgesia via peroxisome proliferator-activated receptor-alpha in a model of inflammatory pain. Neuropharmacology 55:85-93
    • (2008) Neuropharmacology , vol.55 , pp. 85-93
    • Jhaveri, M.D.1    Richardson, D.2    Robinson, I.3
  • 46
    • 35648959293 scopus 로고    scopus 로고
    • The novel endocannabinoid receptor GPR55 is activated by atypical cannabinoids but does not mediate their vasodilator effects
    • Johns DG, Behm DJ, Walker DJ et al. (2007) The novel endocannabinoid receptor GPR55 is activated by atypical cannabinoids but does not mediate their vasodilator effects. Br J Pharmacol 152:825-831
    • (2007) Br J Pharmacol , vol.152 , pp. 825-831
    • Johns, D.G.1    Behm, D.J.2    Walker, D.J.3
  • 47
    • 27944510259 scopus 로고    scopus 로고
    • Cannabinoid receptor type 2 gene is associated with human osteoporosis
    • Karsak M, Cohen-Solal M, Freudenberg J et al. (2005) Cannabinoid receptor type 2 gene is associated with human osteoporosis. Hum Mol Genet 14:3389-3396
    • (2005) Hum Mol Genet , vol.14 , pp. 3389-3396
    • Karsak, M.1    Cohen-Solal, M.2    Freudenberg, J.3
  • 48
    • 0037234363 scopus 로고    scopus 로고
    • Modulation of anxiety through blockade of anandamide hydrolysis
    • Kathuria S, Gaetani S, Fegley D et al. (2003) Modulation of anxiety through blockade of anandamide hydrolysis. Nat Med 9:76-81
    • (2003) Nat Med , vol.9 , pp. 76-81
    • Kathuria, S.1    Gaetani, S.2    Fegley, D.3
  • 49
    • 0034747415 scopus 로고    scopus 로고
    • Selective cannabinoid CB1 receptor activation inhibits spinal nociceptive transmission in vivo
    • Kelly S, Chapman V (2001) Selective cannabinoid CB1 receptor activation inhibits spinal nociceptive transmission in vivo. J Neurophysiol 86:3061-3064
    • (2001) J Neurophysiol , vol.86 , pp. 3061-3064
    • Kelly, S.1    Chapman, V.2
  • 50
    • 0037052626 scopus 로고    scopus 로고
    • Spinal administration of capsazepine inhibits noxious evoked responses of dorsal horn neurons in non-inflamed and carrageenan inflamed rats
    • Kelly S, Chapman V (2002) Spinal administration of capsazepine inhibits noxious evoked responses of dorsal horn neurons in non-inflamed and carrageenan inflamed rats. Brain Res 935:103-108
    • (2002) Brain Res , vol.935 , pp. 103-108
    • Kelly, S.1    Chapman, V.2
  • 51
    • 0142102352 scopus 로고    scopus 로고
    • Cannabinoid CB(1) receptor inhibition of mechanically evoked responses of spinal neurones in control rats, but not in rats with hindpaw inflammation
    • Kelly S, Chapman V (2003) Cannabinoid CB(1) receptor inhibition of mechanically evoked responses of spinal neurones in control rats, but not in rats with hindpaw inflammation. Eur J Pharmacol 474:209-216
    • (2003) Eur J Pharmacol , vol.474 , pp. 209-216
    • Kelly, S.1    Chapman, V.2
  • 52
    • 1642422400 scopus 로고    scopus 로고
    • Activation of peripheral cannabinoid CB1 receptors inhibits mechanically evoked responses of spinal neurons in noninflamed rats and rats with hindpaw inflammation
    • Kelly S, Jhaveri MD, Sagar DR et al. (2003) Activation of peripheral cannabinoid CB1 receptors inhibits mechanically evoked responses of spinal neurons in noninflamed rats and rats with hindpaw inflammation. Eur J Neurosci 18:2239-2243
    • (2003) Eur J Neurosci , vol.18 , pp. 2239-2243
    • Kelly, S.1    Jhaveri, M.D.2    Sagar, D.R.3
  • 53
    • 40649102938 scopus 로고    scopus 로고
    • GPR55 is a cannabinoid receptor that increases intracellular calcium and inhibits M current
    • Lauckner JE, Jensen JB, Chen HY et al. (2008) GPR55 is a cannabinoid receptor that increases intracellular calcium and inhibits M current. Proc Natl Acad Sci USA 105:2699-2704
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 2699-2704
    • Lauckner, J.E.1    Jensen, J.B.2    Chen, H.Y.3
  • 54
    • 33645935391 scopus 로고    scopus 로고
    • Inactivation of N-acyl phosphatidylethanolamine phospholipase D reveals multiple mechanisms for the biosynthesis of endocannabinoids
    • Leung D, Saghatelian A, Simon GMet al. (2006) Inactivation of N-acyl phosphatidylethanolamine phospholipase D reveals multiple mechanisms for the biosynthesis of endocannabinoids. Biochemistry 45:4720-4726
    • (2006) Biochemistry , vol.45 , pp. 4720-4726
    • Leung, D.1    Saghatelian, A.2    Simon, G.M.3
  • 55
    • 0030087731 scopus 로고    scopus 로고
    • Investigation of brain sites mediating cannabinoidinduced antinociception in rats: Evidence supporting periaqueductal gray involvement
    • Lichtman AH, Cook SA, Martin BR (1996) Investigation of brain sites mediating cannabinoidinduced antinociception in rats: evidence supporting periaqueductal gray involvement. J Pharmacol Exp Ther 276:585-593
    • (1996) J Pharmacol Exp Ther , vol.276 , pp. 585-593
    • Lichtman, A.H.1    Cook, S.A.2    Martin, B.R.3
  • 56
    • 4644354869 scopus 로고    scopus 로고
    • Reversible inhibitors of fatty acid amide hydrolase that promote analgesia: Evidence for an unprecedented combination of potency and selectivity
    • Lichtman AH, Leung D, Shelton CC et al. (2004a) Reversible inhibitors of fatty acid amide hydrolase that promote analgesia: evidence for an unprecedented combination of potency and selectivity. J Pharmacol Exp Ther 311:441-448
    • (2004) J Pharmacol Exp Ther , vol.311 , pp. 441-448
    • Lichtman, A.H.1    Leung, D.2    Shelton, C.C.3
  • 57
    • 2442510225 scopus 로고    scopus 로고
    • Mice lacking fatty acid amide hydrolase exhibit a cannabinoid receptor-mediated phenotypic hypoalgesia
    • Lichtman AH, Shelton CC, Advani T et al. (2004b) Mice lacking fatty acid amide hydrolase exhibit a cannabinoid receptor-mediated phenotypic hypoalgesia. Pain 109:319-327
    • (2004) Pain , vol.109 , pp. 319-327
    • Lichtman, A.H.1    Shelton, C.C.2    Advani, T.3
  • 59
    • 37349020974 scopus 로고    scopus 로고
    • Multiple pathways involved in the biosynthesis of anandamide
    • Liu J, Wang L, Harvey-White J et al. (2008) Multiple pathways involved in the biosynthesis of anandamide. Neuropharmacology 54:1-7
    • (2008) Neuropharmacology , vol.54 , pp. 1-7
    • Liu, J.1    Wang, L.2    Harvey-White, J.3
  • 60
    • 33144480327 scopus 로고    scopus 로고
    • Cannabinoid receptors as therapeutic targets
    • Mackie K (2006) Cannabinoid receptors as therapeutic targets. Annu Rev Pharmacol Toxicol 46:101-122
    • (2006) Annu Rev Pharmacol Toxicol , vol.46 , pp. 101-122
    • Mackie, K.1
  • 61
    • 33947319316 scopus 로고    scopus 로고
    • Analgesic actions of N-arachidonoylserotonin, a fatty acid amide hydrolase inhibitor with antagonistic activity at vanilloid TRPV1 receptors
    • Maione S, De Petrocellis L, de Novellis V et al. (2007) Analgesic actions of N-arachidonoylserotonin, a fatty acid amide hydrolase inhibitor with antagonistic activity at vanilloid TRPV1 receptors. Br J Pharmacol 150:766-781
    • (2007) Br J Pharmacol , vol.150 , pp. 766-781
    • Maione, S.1    de Petrocellis, L.2    de Novellis, V.3
  • 62
    • 0034886018 scopus 로고    scopus 로고
    • CB2 cannabinoid receptor-mediated peripheral antinociception
    • Malan TP Jr, Ibrahim MM, Deng H et al. (2001) CB2 cannabinoid receptor-mediated peripheral antinociception. Pain 93:239-245
    • (2001) Pain , vol.93 , pp. 239-245
    • Malan Jr., T.P.1    Ibrahim, M.M.2    Deng, H.3
  • 63
    • 0037302086 scopus 로고    scopus 로고
    • CB2 cannabinoid receptor agonists: Pain relief without psychoactive effects?
    • Malan TP Jr, Ibrahim MM, Lai J et al. (2003) CB2 cannabinoid receptor agonists: pain relief without psychoactive effects? Curr Opin Pharmacol 3:62-67
    • (2003) Curr Opin Pharmacol , vol.3 , pp. 62-67
    • Malan Jr., T.P.1    Ibrahim, M.M.2    Lai, J.3
  • 64
    • 0033586315 scopus 로고    scopus 로고
    • Anatomical basis for cannabinoid-induced antinociception as revealed by intracerebral microinjections
    • Martin WJ, Coffin PO, Attias E et al. (1999) Anatomical basis for cannabinoid-induced antinociception as revealed by intracerebral microinjections. Brain Res 822:237-242
    • (1999) Brain Res , vol.822 , pp. 237-242
    • Martin, W.J.1    Coffin, P.O.2    Attias, E.3
  • 65
    • 0029012014 scopus 로고
    • Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors
    • Mechoulam R, Ben-Shabat S, Hanus L et al. (1995) Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors. Biochem Pharmacol 50:83-90
    • (1995) Biochem Pharmacol , vol.50 , pp. 83-90
    • Mechoulam, R.1    Ben-Shabat, S.2    Hanus, L.3
  • 66
    • 0032563792 scopus 로고    scopus 로고
    • An analgesia circuit activated by cannabinoids
    • Meng ID, Manning BH, Martin WJ et al. (1998) An analgesia circuit activated by cannabinoids. Nature 395:381-383
    • (1998) Nature , vol.395 , pp. 381-383
    • Meng, I.D.1    Manning, B.H.2    Martin, W.J.3
  • 67
    • 33751244807 scopus 로고    scopus 로고
    • Site-specific increases in peripheral cannabinoid receptors and their endogenous ligands in a model of neuropathic pain
    • Mitrirattanakul S, Ramakul N, Guerrero AV et al. (2006) Site-specific increases in peripheral cannabinoid receptors and their endogenous ligands in a model of neuropathic pain. Pain 126:102-114
    • (2006) Pain , vol.126 , pp. 102-114
    • Mitrirattanakul, S.1    Ramakul, N.2    Guerrero, A.V.3
  • 68
    • 31444437185 scopus 로고    scopus 로고
    • Peripheral cannabinoid receptor, CB2, regulates bone mass
    • Ofek O, Karsak M, Leclerc N et al. (2006) Peripheral cannabinoid receptor, CB2, regulates bone mass. Proc Natl Acad Sci USA 103:696-701
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 696-701
    • Ofek, O.1    Karsak, M.2    Leclerc, N.3
  • 69
    • 0035150352 scopus 로고    scopus 로고
    • Cannabinoid receptors and pain
    • Pertwee RG (2001) Cannabinoid receptors and pain. Prog Neurobiol 63:569-611
    • (2001) Prog Neurobiol , vol.63 , pp. 569-611
    • Pertwee, R.G.1
  • 70
    • 33846389346 scopus 로고    scopus 로고
    • Changes in spinal and supraspinal endocannabinoid levels in neuropathic rats
    • Petrosino S, Palazzo E, de Novellis V et al. (2007) Changes in spinal and supraspinal endocannabinoid levels in neuropathic rats. Neuropharmacology 52:415-422
    • (2007) Neuropharmacology , vol.52 , pp. 415-422
    • Petrosino, S.1    Palazzo, E.2    de Novellis, V.3
  • 71
    • 0036260823 scopus 로고    scopus 로고
    • Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at theCB1 receptor
    • Porter AC, Sauer JM, Knierman MD et al. (2002) Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at theCB1 receptor. J Pharmacol Exp Ther 301:1020-1024
    • (2002) J Pharmacol Exp Ther , vol.301 , pp. 1020-1024
    • Porter, A.C.1    Sauer, J.M.2    Knierman, M.D.3
  • 72
    • 0036019404 scopus 로고    scopus 로고
    • Endocannabinoids and pain: Spinal and peripheral analgesia in inflammation and neuropathy
    • Rice AS, Farquhar-Smith WP, Nagy I (2002) Endocannabinoids and pain: spinal and peripheral analgesia in inflammation and neuropathy. Prostaglandins Leukot Essent Fatty Acids 66:243-256
    • (2002) Prostaglandins Leukot Essent Fatty Acids , vol.66 , pp. 243-256
    • Rice, A.S.1    Farquhar-Smith, W.P.2    Nagy, I.3
  • 73
    • 0031779305 scopus 로고    scopus 로고
    • Cannabinoids reduce hyperalgesia and inflammation via interaction with peripheral CB1 receptors
    • Richardson JD, Kilo S, Hargreaves KM (1998) Cannabinoids reduce hyperalgesia and inflammation via interaction with peripheral CB1 receptors. Pain 75:111-119
    • (1998) Pain , vol.75 , pp. 111-119
    • Richardson, J.D.1    Kilo, S.2    Hargreaves, K.M.3
  • 74
    • 43249115359 scopus 로고    scopus 로고
    • Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis
    • Richardson D, Pearson RG, Kurian N et al. (2008) Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis. Arthritis Res Ther 10:R43
    • (2008) Arthritis Res Ther , vol.10
    • Richardson, D.1    Pearson, R.G.2    Kurian, N.3
  • 75
    • 41149137558 scopus 로고    scopus 로고
    • Spinal microglial and perivascular cell cannabinoid receptor type 2 activation reduces behavioral hypersensitivity without tolerance after peripheral nerve injury
    • Romero-Sandoval A, Nutile-McMenemy N, DeLeo JA (2008) Spinal microglial and perivascular cell cannabinoid receptor type 2 activation reduces behavioral hypersensitivity without tolerance after peripheral nerve injury. Anesthesiology 108:722-734
    • (2008) Anesthesiology , vol.108 , pp. 722-734
    • Romero-Sandoval, A.1    Nutile-McMenemy, N.2    DeLeo, J.A.3
  • 76
    • 34250750792 scopus 로고    scopus 로고
    • The fatty-acid amide hydrolase inhibitor URB597 (cyclohexyl carbamic acid 30-carbamoyl-biphenyl-3-yl ester) reduces neuropathic pain after oral administration in mice
    • Russo R, Loverme J, La Rana G et al. (2007) The fatty-acid amide hydrolase inhibitor URB597 (cyclohexyl carbamic acid 30-carbamoyl-biphenyl-3-yl ester) reduces neuropathic pain after oral administration in mice. J Pharmacol Exp Ther 322:236-242
    • (2007) J Pharmacol Exp Ther , vol.322 , pp. 236-242
    • Russo, R.1    Loverme, J.2    La Rana, G.3
  • 77
    • 35649015179 scopus 로고    scopus 로고
    • The orphan receptor GPR55 is a novel cannabinoid receptor
    • Ryberg E, Larsson N, Sjogren S et al. (2007) The orphan receptor GPR55 is a novel cannabinoid receptor. Br J Pharmacol 152:1092-1101
    • (2007) Br J Pharmacol , vol.152 , pp. 1092-1101
    • Ryberg, E.1    Larsson, N.2    Sjogren, S.3
  • 78
    • 23244444097 scopus 로고    scopus 로고
    • Inhibitory effects of CB1 and CB2 receptor agonists on responses of DRG neurons and dorsal horn neurons in neuropathic rats
    • Sagar DR, Kelly S, Millns PJ et al. (2005) Inhibitory effects of CB1 and CB2 receptor agonists on responses of DRG neurons and dorsal horn neurons in neuropathic rats. Eur J Neurosci 22:371-379
    • (2005) Eur J Neurosci , vol.22 , pp. 371-379
    • Sagar, D.R.1    Kelly, S.2    Millns, P.J.3
  • 79
    • 38149076483 scopus 로고    scopus 로고
    • Cannabinoid-mediated antinociception is enhanced in rat osteoarthritic knees
    • Schuelert N, McDougall JJ (2008) Cannabinoid-mediated antinociception is enhanced in rat osteoarthritic knees. Arthritis Rheum 58:145-153
    • (2008) Arthritis Rheum , vol.58 , pp. 145-153
    • Schuelert, N.1    McDougall, J.J.2
  • 80
    • 1842685334 scopus 로고    scopus 로고
    • Evidence that CB-1 and CB-2 cannabinoid receptors mediate antinociception in neuropathic pain in the rat
    • Scott DA, Wright CE, Angus JA (2004) Evidence that CB-1 and CB-2 cannabinoid receptors mediate antinociception in neuropathic pain in the rat. Pain 109:124-131
    • (2004) Pain , vol.109 , pp. 124-131
    • Scott, D.A.1    Wright, C.E.2    Angus, J.A.3
  • 81
    • 44049087532 scopus 로고    scopus 로고
    • Anandamide biosynthesis catalyzed by the phosphodiesterase GDE1 and detection of glycerophospho-N-acyl ethanolamine precursors in mouse brain
    • Simon GM, Cravatt BF (2008) Anandamide biosynthesis catalyzed by the phosphodiesterase GDE1 and detection of glycerophospho-N-acyl ethanolamine precursors in mouse brain. J Biol Chem 283:9341-9349
    • (2008) J Biol Chem , vol.283 , pp. 9341-9349
    • Simon, G.M.1    Cravatt, B.F.2
  • 82
    • 0032056333 scopus 로고    scopus 로고
    • Characterization of delta9-tetrahydrocannabinol and anandamide antinociception in nonarthritic and arthritic rats
    • Smith FL, Fujimori K, Lowe J et al. (1998) Characterization of delta9-tetrahydrocannabinol and anandamide antinociception in nonarthritic and arthritic rats. Pharmacol Biochem Behav 60:183-191
    • (1998) Pharmacol Biochem Behav , vol.60 , pp. 183-191
    • Smith, F.L.1    Fujimori, K.2    Lowe, J.3
  • 83
    • 0037966402 scopus 로고    scopus 로고
    • Intraplantar injection of anandamide inhibits mechanically-evoked responses of spinal neurones via activation of CB2 receptors in anaesthetised rats
    • Sokal DM, Elmes SJ, Kendall DA et al. (2003) Intraplantar injection of anandamide inhibits mechanically-evoked responses of spinal neurones via activation of CB2 receptors in anaesthetised rats. Neuropharmacology 45:404-411
    • (2003) Neuropharmacology , vol.45 , pp. 404-411
    • Sokal, D.M.1    Elmes, S.J.2    Kendall, D.A.3
  • 84
    • 33747598488 scopus 로고    scopus 로고
    • Involvement of neuronal cannabinoid receptor CB1 in regulation of bone mass and bone remodeling
    • Tam J, Ofek O, Fride E et al. (2006) Involvement of neuronal cannabinoid receptor CB1 in regulation of bone mass and bone remodeling. Mol Pharmacol 70:786-792
    • (2006) Mol Pharmacol , vol.70 , pp. 786-792
    • Tam, J.1    Ofek, O.2    Fride, E.3
  • 85
    • 0031929438 scopus 로고    scopus 로고
    • Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous system
    • Tsou K, Brown S, Sanudo-Pena MC et al. (1998) Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous system. Neuroscience 83:393-411
    • (1998) Neuroscience , vol.83 , pp. 393-411
    • Tsou, K.1    Brown, S.2    Sanudo-Pena, M.C.3
  • 86
    • 34548513526 scopus 로고    scopus 로고
    • The N-acylethanolamine-hydrolyzing acid amidase (NAAA)
    • Tsuboi K, Takezaki N, Ueda N (2007) The N-acylethanolamine-hydrolyzing acid amidase (NAAA). Chem Biodivers 4:1914-1925
    • (2007) Chem Biodivers , vol.4 , pp. 1914-1925
    • Tsuboi, K.1    Takezaki, N.2    Ueda, N.3
  • 87
    • 20144388149 scopus 로고    scopus 로고
    • Pharmacological and pharmacokinetic characterization of the cannabinoid receptor 2 agonist, GW405833, utilizing rodent models of acute and chronic pain, anxiety, ataxia and catalepsy
    • Valenzano KJ, Tafesse L, Lee G et al. (2005) Pharmacological and pharmacokinetic characterization of the cannabinoid receptor 2 agonist, GW405833, utilizing rodent models of acute and chronic pain, anxiety, ataxia and catalepsy. Neuropharmacology 48:658-672
    • (2005) Neuropharmacology , vol.48 , pp. 658-672
    • Valenzano, K.J.1    Tafesse, L.2    Lee, G.3
  • 88
    • 26844504226 scopus 로고    scopus 로고
    • Identification and functional characterization of brainstem cannabinoid CB2 receptors
    • Van Sickle MD, Duncan M, Kingsley PJ et al. (2005) Identification and functional characterization of brainstem cannabinoid CB2 receptors. Science 310:329-332
    • (2005) Science , vol.310 , pp. 329-332
    • van Sickle, M.D.1    Duncan, M.2    Kingsley, P.J.3
  • 90
    • 0032716177 scopus 로고    scopus 로고
    • Pain modulation by release of the endogenous cannabinoid anandamide
    • Walker JM, Huang SM, Strangman NMet al. (1999) Pain modulation by release of the endogenous cannabinoid anandamide. Proc Natl Acad Sci USA 96:12198-12203
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 12198-12203
    • Walker, J.M.1    Huang, S.M.2    Strangman, N.M.3
  • 91
    • 0026639295 scopus 로고
    • Antinociceptive activity of intrathecally administered cannabinoids alone, and in combination with morphine, in mice
    • Welch SP, Stevens DL (1992) Antinociceptive activity of intrathecally administered cannabinoids alone, and in combination with morphine, in mice. J Pharmacol Exp Ther 262:10-18
    • (1992) J Pharmacol Exp Ther , vol.262 , pp. 10-18
    • Welch, S.P.1    Stevens, D.L.2
  • 92
    • 0032160418 scopus 로고    scopus 로고
    • Differential blockade of the antinociceptive effects of centrally administered cannabinoids by SR141716A
    • Welch SP, Huffman JW, Lowe J (1998) Differential blockade of the antinociceptive effects of centrally administered cannabinoids by SR141716A. J Pharmacol Exp Ther 286:1301-1308
    • (1998) J Pharmacol Exp Ther , vol.286 , pp. 1301-1308
    • Welch, S.P.1    Huffman, J.W.2    Lowe, J.3
  • 93
    • 33745618444 scopus 로고    scopus 로고
    • The use of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis
    • (Oxford) author reply 781-782
    • Wright S, Ware M, Guy G (2006) The use of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis. Rheumatology (Oxford) 45, 781; author reply 781-782
    • (2006) Rheumatology , vol.45 , pp. 781
    • Wright, S.1    Ware, M.2    Guy, G.3
  • 94
    • 39749122600 scopus 로고    scopus 로고
    • Involvement of central cannabinoid CB2 receptor in reducing mechanical allodynia in a mouse model of neuropathic pain
    • Yamamoto W, Mikami T, Iwamura H (2008) Involvement of central cannabinoid CB2 receptor in reducing mechanical allodynia in a mouse model of neuropathic pain. Eur J Pharmacol 583:56-61
    • (2008) Eur J Pharmacol , vol.583 , pp. 56-61
    • Yamamoto, W.1    Mikami, T.2    Iwamura, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.