Activation of CB1 and CB2 receptors attenuates the induction and maintenance of inflammatory pain in the rat

Pain

Volumn 118, Issue 3, 2005, Pages 327-335

  Elmes, Steven J R ^a   Winyard, Lisa A ^b   Medhurst, Stephen J ^b   Clayton, Nick M ^b   Wilson, Alex W ^b   Kendall, David A ^a   Chapman, Victoria ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Cannabinoids; Carrageenan induced inflammation; CB1 cannabinoid receptor; CB2 cannabinoid receptor; Inflammatory hyperalgesia; Inflammatory oedema; Rat; Weight bearing

Indexed keywords

1 DEOXY 3 (1,1 DIMETHYLBUTYL) DELTA8 TETRAHYDROCANNABINOL; CANNABINOID 1 RECEPTOR; CANNABINOID 2 RECEPTOR; CANNABINOID RECEPTOR AGONIST; CARRAGEENAN; CYCLOOXYGENASE 2 INHIBITOR; DEXANABINOL; MORPHINE; MU OPIATE RECEPTOR AGONIST; ROFECOXIB; UNCLASSIFIED DRUG; 1,1 DIMETHYLBUTYL 1 DEOXY DELTA(9) THC; 1,1-DIMETHYLBUTYL-1-DEOXY-DELTA(9)-THC; ANALGESIC AGENT; CANNABINOID; CANNABINOID RECEPTOR CB2, RAT; DRUG DERIVATIVE; TETRAHYDROCANNABINOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; EDEMA; HYPERALGESIA; HYPERSENSITIVITY; INFLAMMATION; MALE; NONHUMAN; PAIN; PAW EDEMA; PRIORITY JOURNAL; RAT; WEIGHT BEARING; ANIMAL; CHEMICALLY INDUCED DISORDER; DRUG COMBINATION; DRUG POTENTIATION; PATHOPHYSIOLOGY; TREATMENT OUTCOME;

ANALGESICS; ANIMALS; CANNABINOIDS; CARRAGEENAN; DRUG COMBINATIONS; HYPERALGESIA; INFLAMMATION; MALE; RATS; RECEPTOR, CANNABINOID, CB1; RECEPTOR, CANNABINOID, CB2; TETRAHYDROCANNABINOL; TREATMENT OUTCOME; WEIGHT-BEARING;

EID: 28644451441     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pain.2005.09.005     Document Type: Article

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