Disruption of adaptive energy metabolism and elevated ribosomal p-S6K1 levels contribute to INCL pathogenesis: Partial rescue by resveratrol

Human Molecular Genetics

Volumn 20, Issue 6, 2011, Pages 1111-1121

  Wei, Hui ^a   Zhang, Zhongjian ^a   Saha, Arjun ^a   Peng, Shiyong ^a   Chandra, Goutam ^a   Quezado, Zenaide ^b   Mukherjee, Anil B ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; ADENYLATE KINASE; NICOTINAMIDE ADENINE DINUCLEOTIDE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; RESVERATROL; S6 KINASE; SIRTUIN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN TISSUE; CELL CULTURE; CONTROLLED STUDY; DEGENERATIVE DISEASE; DOWN REGULATION; ENERGY METABOLISM; FIBROBLAST; HUMAN; HUMAN CELL; LIFESPAN; LONGEVITY; LYSOSOME STORAGE DISEASE; METABOLIC DISORDER; MOUSE; NEURONAL CEROID LIPOFUSCINOSIS INFANTILE FINNISH TYPE; NEWBORN; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

ANIMALS; CELLS, CULTURED; ENERGY METABOLISM; FIBROBLASTS; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NAD; NEURONAL CEROID-LIPOFUSCINOSES; OXIDATIVE STRESS; PHOSPHORYLATION; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; RIBOSOMAL PROTEIN S6 KINASES, 90-KDA; RIBOSOMES; STILBENES; THIOLESTER HYDROLASES; UP-REGULATION;

MUS; RICE STRIPE VIRUS;

EID: 79952019175     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddq555     Document Type: Article

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