Palmitoyl-protein thioesterase-1 deficiency leads to the activation of caspase-9 and contributes to rapid neurodegeneration in INCL

Human Molecular Genetics

Volumn 15, Issue 10, 2006, Pages 1580-1586

  Kim, Sung Jo ^a   Zhang, Zhongjian ^a   Lee, Yi Ching ^a   Mukherjee, Anil B ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 12; CASPASE 3; CASPASE 9; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PALMITOYL PROTEIN THIOESTERASE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CALCIUM HOMEOSTASIS; CELL FUNCTION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME DEFICIENCY; ENZYME DEGRADATION; ENZYME LOCALIZATION; GENE INACTIVATION; GENE MUTATION; GENETIC CODE; GENETIC LINKAGE; GENETIC PREDISPOSITION; GENETIC RISK; HUMAN; HUMAN CELL; HUMAN TISSUE; MITOCHONDRIAL MEMBRANE; MOUSE; NERVE CELL DEGENERATION; NERVE DEGENERATION; NEURONAL CEROID LIPOFUSCINOSIS; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION;

ANIMALS; APOPTOSIS; BRAIN; CALCIUM; CASPASE 3; CASPASE 9; CASPASES; CELLS, CULTURED; COLLAGEN TYPE XI; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; HUMANS; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; NERVE DEGENERATION; NEURONAL CEROID-LIPOFUSCINOSES; POLY(ADP-RIBOSE) POLYMERASES; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE;

EID: 33744761561     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddl078     Document Type: Article

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